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Volumn 88, Issue 5, 2011, Pages 388-401

A scaffold-free multicellular three-dimensional in vitro model of osteogenesis

Author keywords

Bone tissue engineering; In vitro model; Marrow explant culture; Osteogenesis; Scaffold free

Indexed keywords

CALCIUM; CD45 ANTIGEN; HERMES ANTIGEN; PHOSPHORUS; TISSUE SCAFFOLD;

EID: 79955627807     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-011-9467-3     Document Type: Article
Times cited : (19)

References (82)
  • 1
    • 0037376627 scopus 로고    scopus 로고
    • Fracture healing as a post-natal developmental process: Molecular, spatial, and temporal aspects of its regulation
    • DOI 10.1002/jcb.10435
    • Gerstenfeld LC, Cullinane DM, Barnes GL, Graves DT, Einhorn TA (2003) Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 88:873-884 (Pubitemid 36337032)
    • (2003) Journal of Cellular Biochemistry , vol.88 , Issue.5 , pp. 873-884
    • Gerstenfeld, L.C.1    Cullinane, D.M.2    Barnes, G.L.3    Graves, D.T.4    Einhorn, T.A.5
  • 3
    • 77954503120 scopus 로고    scopus 로고
    • The sequential production profiles of growth factors and their relations to bone volume in ossifying bone marrow explants
    • Gurkan UA, Gargac J, Akkus O (2010) The sequential production profiles of growth factors and their relations to bone volume in ossifying bone marrow explants. Tissue Eng A 16:2295-2306
    • (2010) Tissue Eng A , vol.16 , pp. 2295-2306
    • Gurkan, U.A.1    Gargac, J.2    Akkus, O.3
  • 5
    • 56449086365 scopus 로고    scopus 로고
    • The mechanical environment of bone marrow: A review
    • Gurkan UA, Akkus O (2008) The mechanical environment of bone marrow: a review. Ann Biomed Eng 36:1978-1991
    • (2008) Ann Biomed Eng , vol.36 , pp. 1978-1991
    • Gurkan, U.A.1    Akkus, O.2
  • 6
    • 79551528372 scopus 로고    scopus 로고
    • Ossifying bone marrow explant culture as a three-dimensional mechanoresponsive in vitro model of osteogenesis
    • Gurkan UA, Krueger A, Akkus O (2010) Ossifying bone marrow explant culture as a three-dimensional mechanoresponsive in vitro model of osteogenesis. Tissue Eng A 17(3-4):417-428
    • (2010) Tissue Eng A , vol.17 , Issue.3-4 , pp. 417-428
    • Gurkan, U.A.1    Krueger, A.2    Akkus, O.3
  • 8
    • 58049196868 scopus 로고    scopus 로고
    • Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues
    • Moioli EK, Clark PA, Chen M, Dennis JE, Erickson HP, Gerson SL, Mao JJ (2008) Synergistic actions of hematopoietic and mesenchymal stem/progenitor cells in vascularizing bioengineered tissues. Plos One 3:e3922
    • (2008) Plos One , vol.3
    • Moioli, E.K.1    Clark, P.A.2    Chen, M.3    Dennis, J.E.4    Erickson, H.P.5    Gerson, S.L.6    Mao, J.J.7
  • 9
    • 65949115924 scopus 로고    scopus 로고
    • Role of the osteoblast lineage in the bone marrow hematopoietic niches
    • Wu JY, Scadden DT, Kronenberg HM (2009) Role of the osteoblast lineage in the bone marrow hematopoietic niches. J Bone Miner Res 24:759-764
    • (2009) J Bone Miner Res , vol.24 , pp. 759-764
    • Wu, J.Y.1    Scadden, D.T.2    Kronenberg, H.M.3
  • 10
    • 42749089216 scopus 로고    scopus 로고
    • Communications between bone cells and hematopoietic stem cells
    • Porter RL, Calvi LM (2008) Communications between bone cells and hematopoietic stem cells. Arch Biochem Biophys 473: 193-200
    • (2008) Arch Biochem Biophys , vol.473 , pp. 193-200
    • Porter, R.L.1    Calvi, L.M.2
  • 11
    • 0034125271 scopus 로고    scopus 로고
    • Bone marrow accessory cells regulate human bone precursor cell development
    • DOI 10.1016/S0301-472X(00)00183-1, PII S0301472X00001831
    • Eipers PG, Kale S, Taichman RS, Pipia GG, Swords NA, Mann KG, Long MW (2000) Bone marrow accessory cells regulate human bone precursor cell development. Exp Hematol 28:815-825 (Pubitemid 30411987)
    • (2000) Experimental Hematology , vol.28 , Issue.7 , pp. 815-825
    • Eipers, P.G.1    Kale, S.2    S, T.R.3    Pipia, G.G.4    Swords, N.A.5    Mann, K.G.6    Long, M.W.7
  • 12
    • 33749557618 scopus 로고    scopus 로고
    • Enrichment of osteogenic cell populations from rat bone marrow stroma
    • DOI 10.1016/j.biomaterials.2006.08.048, PII S014296120600754X
    • van den Dolder J, Jansen JA (2007) Enrichment of osteogenic cell populations from rat bone marrow stroma. Biomaterials 28: 249-255 (Pubitemid 44537388)
    • (2007) Biomaterials , vol.28 , Issue.2 , pp. 249-255
    • Van Den, D.J.1    Jansen, J.A.2
  • 13
    • 0030051856 scopus 로고    scopus 로고
    • Human osteoblasts support human hematopoietic progenitor cells in in vitro bone marrow cultures
    • Taichman RS, Reilly MJ, Emerson SG (1996) Human osteoblasts support human hematopoietic progenitor cells in in vitro bone marrow cultures. Blood 87:518-524 (Pubitemid 26030307)
    • (1996) Blood , vol.87 , Issue.2 , pp. 518-524
    • Taichman, R.S.1    Reilly, M.J.2    Emerson, S.G.3
  • 14
    • 0035120769 scopus 로고    scopus 로고
    • Hepatocyte growth factor is secreted by osteoblasts and cooperatively permits the survival of haematopoietic progenitors
    • DOI 10.1046/j.1365-2141.2001.02568.x
    • Taichman RS, Reilly MJ, Verma RS, Ehrenman K, Emerson SG (2001) Hepatocyte growth factor is secreted by osteoblasts and cooperatively permits the survival of haematopoietic progenitors. Br J Haematol 112:438-448 (Pubitemid 32183492)
    • (2001) British Journal of Haematology , vol.112 , Issue.2 , pp. 438-448
    • Taichman, R.S.1    Reilly, M.J.2    Verma, R.S.3    Ehrenman, K.4    Emerson, S.G.5
  • 16
    • 77951455778 scopus 로고    scopus 로고
    • Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function
    • Chitteti BR, Cheng Y-H, Poteat B, Rodriguez-Rodriguez S, Goebel WS, Carlesso N, Kacena MA, Srour EF (2010) Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function. Blood 115:3239-3248
    • (2010) Blood , vol.115 , pp. 3239-3248
    • Chitteti, B.R.1    Cheng, Y.-H.2    Poteat, B.3    Rodriguez-Rodriguez, S.4    Goebel, W.S.5    Carlesso, N.6    Kacena, M.A.7    Srour, E.F.8
  • 17
    • 0036545423 scopus 로고    scopus 로고
    • Progressive development of the osteoblast phenotype during differentiation of osteoprogenitor cells derived from fetal rat calvaria: Model for in vitro bone formation
    • DOI 10.1248/bpb.25.509
    • Yamamoto N, Furuya K, Hanada K (2002) Progressive development of the osteoblast phenotype during differentiation of osteoprogenitor cells derived from fetal rat calvaria: model for in vitro bone formation. Biol Pharm Bull 25:509-515 (Pubitemid 40036744)
    • (2002) Biological and Pharmaceutical Bulletin , vol.25 , Issue.4 , pp. 509-515
    • Yamamoto, N.1    Furuya, K.2    Hanada, K.3
  • 18
    • 34548642562 scopus 로고    scopus 로고
    • The sequential expression profiles of growth factors from osteroprogenitors to osteoblasts in vitro
    • DOI 10.1089/ten.2006.0423
    • Huang ZN, Nelson ER, Smith RL, Goodman SB (2007) The sequential expression profiles of growth factors from osteroprogenitors to osteoblasts in vitro. Tissue Eng 13:2311-2320 (Pubitemid 47404446)
    • (2007) Tissue Engineering , vol.13 , Issue.9 , pp. 2311-2320
    • Huang, Z.1    Nelson, E.R.2    Smith, R.L.3    Goodman, S.B.4
  • 19
    • 0027395886 scopus 로고
    • Formation of mineralized nodules by bone derived cells in vitro: A model of bone formation?
    • DOI 10.1002/ajmg.1320450205
    • Beresford JN, Graves SE, Smoothy CA (1993) Formation of mineralized nodules by bone derived cells in vitro - a model of bone formation. Am J Med Genet 45:163-178 (Pubitemid 23030688)
    • (1993) American Journal of Medical Genetics , vol.45 , Issue.2 , pp. 163-178
    • Beresford, J.N.1    Graves, S.E.2    Smoothy, C.A.3
  • 20
    • 0028346280 scopus 로고
    • Cellular expression of bone-related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures
    • Malaval L, Modrowski D, Gupta AK, Aubin JE (1994) Cellular expression of bone-related proteins during in-vitro osteogenesis in rat bone-marrow stromal cell cultures. J Cell Physiol 158: 555-572 (Pubitemid 24094439)
    • (1994) Journal of Cellular Physiology , vol.158 , Issue.3 , pp. 555-572
    • Malaval, L.1    Modrowski, D.2    Gupta, A.K.3    Aubin, J.E.4
  • 21
    • 0036359415 scopus 로고    scopus 로고
    • Tissue culture models for studies of hormone and vitamin action in bone cells
    • PII S008367290264004X
    • Bodine PVN, Komm BS (2002) Tissue culture models for studies of hormone and vitamin action in bone cells. Vitam Horm 64:101-151 (Pubitemid 135763163)
    • (2002) Vitamins and Hormones , vol.64 , pp. 101-151
    • Bodine, P.V.N.1    Komm, B.S.2
  • 22
    • 0028331071 scopus 로고
    • 3on osteoclast formation in fetal mouse metatarsal organ cultures
    • DOI 10.1016/8756-3282(94)90711-0
    • Tao H, Minkin C (1994) The effects of 1,25-dihydroxyvitamin D3 on osteoclast formation in fetal mouse metatarsal organ cultures. Bone 15:217-223 (Pubitemid 24116087)
    • (1994) Bone , vol.15 , Issue.2 , pp. 217-223
    • Tao, H.1    Minkin, C.2
  • 23
    • 76949090691 scopus 로고    scopus 로고
    • Nonviral transfection of mouse calvarial organ in vitro using accell-modified siRNA
    • Gupta AK, Eshraghi Y, Gliniak C, Gosain AK (2010) Nonviral transfection of mouse calvarial organ in vitro using accell-modified siRNA. Plast Reconstr Surg 125:494-501
    • (2010) Plast Reconstr Surg , vol.125 , pp. 494-501
    • Gupta, A.K.1    Eshraghi, Y.2    Gliniak, C.3    Gosain, A.K.4
  • 24
    • 0036181393 scopus 로고    scopus 로고
    • Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing
    • Cho TJ, Gerstenfeld LC, Einhorn TA (2002) Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing. J Bone Miner Res 17:513-520 (Pubitemid 34171766)
    • (2002) Journal of Bone and Mineral Research , vol.17 , Issue.3 , pp. 513-520
    • Cho, T.-J.1    Gerstenfeld, L.C.2    Einhorn, T.A.3
  • 25
    • 0035075677 scopus 로고    scopus 로고
    • Molecular aspects of healing in stabilized and non-stabilized fractures
    • DOI 10.1016/S0736-0266(00)00006-1, PII S0736026600000061
    • Le AX, Miclau T, Hu D, Helms JA (2001) Molecular aspects of healing in stabilized and non-stabilized fractures. J Orthop Res 19:78-84 (Pubitemid 32288639)
    • (2001) Journal of Orthopaedic Research , vol.19 , Issue.1 , pp. 78-84
    • Le, A.X.1    Miclau, T.2    Hu, D.3    Helms, J.A.4
  • 26
    • 0033768358 scopus 로고    scopus 로고
    • Expression of various growth factors for cell proliferation and cytodifferentiation during fracture repair of bone
    • Tatsuyama K, Maezawa Y, Baba H, Imamura Y, Fukuda M (2000) Expression of various growth factors for cell proliferation and cytodifferentiation during fracture repair of bone. Eur J Histochem 44:269-278
    • (2000) Eur J Histochem , vol.44 , pp. 269-278
    • Tatsuyama, K.1    Maezawa, Y.2    Baba, H.3    Imamura, Y.4    Fukuda, M.5
  • 27
    • 0031949178 scopus 로고    scopus 로고
    • A nude mouse model for human bone formation in unloaded conditions
    • Muraglia A, Martin I, Cancedda R, Quarto R (1998) A nude mouse model for human bone formation in unloaded conditions. Bone 22:131s-134s
    • (1998) Bone , vol.22
    • Muraglia, A.1    Martin, I.2    Cancedda, R.3    Quarto, R.4
  • 29
    • 0036376885 scopus 로고    scopus 로고
    • A model for intramembranous ossification during fracture healing
    • Thompson Z, Miclau T, Hu D, Helms JA (2002) A model for intramembranous ossification during fracture healing. J Orthop Res 20:1091-1098
    • (2002) J Orthop Res , vol.20 , pp. 1091-1098
    • Thompson, Z.1    Miclau, T.2    Hu, D.3    Helms, J.A.4
  • 30
    • 23744472983 scopus 로고    scopus 로고
    • Gene expression perturbation in vitro - A growing case for three-dimensional (3D) culture systems
    • DOI 10.1016/j.semcancer.2005.06.009, PII S1044579X05000416
    • Birgersdotter A, Sandberg R, Ernberg I (2005) Gene expression perturbation in vitro - a growing case for three-dimensional (3D) culture systems. Semin Cancer Biol 15:405-412 (Pubitemid 41140308)
    • (2005) Seminars in Cancer Biology , vol.15 , Issue.5 SPEC. ISS , pp. 405-412
    • Birgersdotter, A.1    Sandberg, R.2    Ernberg, I.3
  • 31
    • 34547931078 scopus 로고    scopus 로고
    • Modeling Tissue Morphogenesis and Cancer in 3D
    • DOI 10.1016/j.cell.2007.08.006, PII S0092867407010288
    • Yamada KM, Cukierman E (2007) Modeling tissue morphogenesis and cancer in 3D. Cell 130:601-610 (Pubitemid 47268064)
    • (2007) Cell , vol.130 , Issue.4 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 32
    • 67650169752 scopus 로고    scopus 로고
    • Hydrogels as extracellular matrix mimics for 3D cell culture
    • Tibbitt MW, Anseth KS (2009) Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng 103:655-663
    • (2009) Biotechnol Bioeng , vol.103 , pp. 655-663
    • Tibbitt, M.W.1    Anseth, K.S.2
  • 33
    • 77049124474 scopus 로고    scopus 로고
    • Modelling tissues in 3D: The next future of pharmaco-toxicology and food research?
    • Mazzoleni G, Di Lorenzo D, Steimberg N (2009) Modelling tissues in 3D: the next future of pharmaco-toxicology and food research? Genes Nutr 4:13-22
    • (2009) Genes Nutr , vol.4 , pp. 13-22
    • Mazzoleni, G.1    Di Lorenzo, D.2    Steimberg, N.3
  • 34
    • 16544380146 scopus 로고    scopus 로고
    • The use of 3-D cultures for high-throughput screening: The multicellular spheroid model
    • Kunz-Schughart LA, Freyer JP, Hofstaedter F, Ebner R (2004) The use of 3-D cultures for high-throughput screening: the multicellular spheroid model. J Biomol Screen 9:273-285
    • (2004) J Biomol Screen , vol.9 , pp. 273-285
    • Kunz-Schughart, L.A.1    Freyer, J.P.2    Hofstaedter, F.3    Ebner, R.4
  • 35
  • 36
    • 0014403633 scopus 로고
    • Transplantation of marrow to extramedullary sites
    • Tavassoli M, Crosby WH (1968) Transplantation of marrow to extramedullary sites. Science 161:54-56
    • (1968) Science , vol.161 , pp. 54-56
    • Tavassoli, M.1    Crosby, W.H.2
  • 37
    • 0023095856 scopus 로고
    • Bone formation in organ cultures of bone marrow
    • Luria EA, Owen ME, Friedenstein AJ, Morris JF, Kuznetsow SA (1987) Bone formation in organ cultures of bone marrow. Cell Tissue Res 248:449-454 (Pubitemid 17042743)
    • (1987) Cell and Tissue Research , vol.248 , Issue.2 , pp. 449-454
    • Luria, E.A.1    Owen, M.E.2    Friedenstein, A.J.3
  • 38
    • 0028534864 scopus 로고
    • 3on osteogenic differentiation of human marrow stromal cells in vitro
    • DOI 10.1016/0003-9969(94)90077-9
    • Beresford JN, Joyner CJ, Devlin C, Triffitt JT (1994) The effects of dexamethasone and 1,25-dihydroxyvitamin D3 on osteogenic differentiation of human marrow stromal cells in-vitro. Arch Oral Biol 39:941-947 (Pubitemid 124034578)
    • (1994) Archives of Oral Biology , vol.39 , Issue.11 , pp. 941-947
    • Beresford, J.N.1    Joyner, C.J.2    Devlin, C.3    Triffitt, J.T.4
  • 39
    • 0031012411 scopus 로고    scopus 로고
    • Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro
    • DOI 10.1002/(SICI)1097-4644(199702)64:2<295::AID-JCB12>3.0.CO;2-I
    • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP (1997) Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 64:295-312 (Pubitemid 27065443)
    • (1997) Journal of Cellular Biochemistry , vol.64 , Issue.2 , pp. 295-312
    • Jaiswal, N.1    Haynesworth, S.E.2    Caplan, A.I.3    Bruder, S.P.4
  • 40
    • 58249119459 scopus 로고    scopus 로고
    • Micro-computed tomography assessment of fracture healing: Relationships among callus structure, composition, and mechanical function
    • Morgan EF, Mason ZD, Chien KB, Pfeiffer AJ, Barnes GL, Einhorn TA, Gerstenfeld LC (2009) Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function. Bone 44:335-344
    • (2009) Bone , vol.44 , pp. 335-344
    • Morgan, E.F.1    Mason, Z.D.2    Chien, K.B.3    Pfeiffer, A.J.4    Barnes, G.L.5    Einhorn, T.A.6    Gerstenfeld, L.C.7
  • 41
    • 0345596449 scopus 로고    scopus 로고
    • Morphometric analysis of human bone biopsies: A quantitative structural comparison of histological sections and micro-computed tomography
    • DOI 10.1016/S8756-3282(98)00068-4
    • Muller R, Van Campenhout H, Van Damme B, Van Der Perre G, Dequeker J, Hildebrand T, Ruegsegger P (1998) Morphometric analysis of human bone biopsies: a quantitative structural comparison of histological sections and micro-computed tomography. Bone 23:59-66 (Pubitemid 28327502)
    • (1998) Bone , vol.23 , Issue.1 , pp. 59-66
    • Muller, R.1    Van Campenhout, H.2    Van Damme, B.3    Van Der, P.G.4    Dequeker, J.5    Hildebrand, T.6    Ruegsegger, P.7
  • 42
    • 34447253328 scopus 로고    scopus 로고
    • Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects
    • DOI 10.1002/jor.20372
    • Oest ME, Dupont KM, Kong HJ, Mooney DJ, Guldberg RE (2007) Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25:941-950 (Pubitemid 47046441)
    • (2007) Journal of Orthopaedic Research , vol.25 , Issue.7 , pp. 941-950
    • Oest, M.E.1    Dupont, K.M.2    Kong, H.-J.3    Mooney, D.J.4    Guldberg, R.E.5
  • 43
    • 70649095070 scopus 로고    scopus 로고
    • Accelerated healing of the rat Achilles tendon in response to autologous conditioned serum
    • Majewski M, Ochsner PE, Liu F, Fluckiger R, Evans CH (2009) Accelerated healing of the rat Achilles tendon in response to autologous conditioned serum. Am J Sports Med 37:2117-2125
    • (2009) Am J Sports Med , vol.37 , pp. 2117-2125
    • Majewski, M.1    Ochsner, P.E.2    Liu, F.3    Fluckiger, R.4    Evans, C.H.5
  • 45
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
    • DOI 10.1210/en.2005-0239
    • Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, Manolagas SC, Jilka RL (2005) Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 146:4577-4583 (Pubitemid 41446595)
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3    Plotkin, L.I.4    Fu, Q.5    O'Brien, C.A.6    Manolagas, S.C.7    Jilka, R.L.8
  • 47
    • 0023337322 scopus 로고
    • Structural variants of human T200 glycoprotein (leukocytecommon antigen)
    • Ralph SJ, Thomas ML, Morton CC, Trowbridge IS (1987) Structural variants of human T200 glycoprotein (leukocytecommon antigen). EMBO J 6:1251-1257
    • (1987) EMBO J , vol.6 , pp. 1251-1257
    • Ralph, S.J.1    Thomas, M.L.2    Morton, C.C.3    Trowbridge, I.S.4
  • 48
    • 0141862027 scopus 로고    scopus 로고
    • Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow
    • DOI 10.1016/S0165-2478(03)00108-1
    • De Ugarte DA, Alfonso Z, Zuk PA, Elbarbary A, Zhu M, Ashjian P, Benhaim P, Hedrick MH, Fraser JK (2003) Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow. Immunol Lett 89:267-270 (Pubitemid 37222456)
    • (2003) Immunology Letters , vol.89 , Issue.2-3 , pp. 267-270
    • De Ugarte, D.A.1    Alfonso, Z.2    Zuk, P.A.3    Elbarbary, A.4    Zhu, M.5    Ashjian, P.6    Benhaim, P.7    Hedrick, M.H.8    Fraser, J.K.9
  • 50
    • 0028102611 scopus 로고
    • + fraction of adult human bone marrow contains the osteogenic precursors
    • Gronthos S, Graves SE, Ohta S, Simmons PJ (1994) The Stro-1+ fraction of adult human bone-marrow contains the osteogenic precursors. Blood 84:4164-4173 (Pubitemid 24371919)
    • (1994) Blood , vol.84 , Issue.12 , pp. 4164-4173
    • Gronthos, S.1    Graves, S.E.2    Ohta, S.3    Simmons, P.J.4
  • 51
    • 0025741349 scopus 로고
    • Identification of stromal cell precursors in human bone-marrow by a novel monoclonal-antibody, Stro-1
    • Simmons PJ, Torokstorb B (1991) Identification of stromal cell precursors in human bone-marrow by a novel monoclonal-antibody, Stro-1. Blood 78:55-62
    • (1991) Blood , vol.78 , pp. 55-62
    • Simmons, P.J.1    Torokstorb, B.2
  • 52
    • 0032895854 scopus 로고    scopus 로고
    • Osteoblastic differentiation and mRNA analysis of STRO-1-positive human bone marrow stromal cells using primary in vitro culture and poly (A) PCR
    • DOI 10.1002/(SICI)1096-9896(199902)187:3<374::AID-PATH257>3.0.CO;2- V
    • Byers RJ, Brown J, Brandwood C, Wood P, Staley W, Hainey L, Freemont AJ, Hoyland JA (1999) Osteoblastic differentiation and mRNA analysis of STRO-1-positive human bone marrow stromal cells using primary in vitro culture and poly (A) PCR. J Pathol 187:374-381 (Pubitemid 29064166)
    • (1999) Journal of Pathology , vol.187 , Issue.3 , pp. 374-381
    • Byers, R.J.1    Brown, J.2    Brandwood, C.3    Wood, P.4    Staley, W.5    Hainey, L.6    Freemont, A.J.7    Hoyland, J.A.8
  • 53
    • 65449129670 scopus 로고    scopus 로고
    • Confocal laser Raman microspectroscopy of biomineralization foci in UMR 106 osteoblastic cultures reveals temporally synchronized protein changes preceding and accompanying mineral crystal deposition
    • Wang CY, Wang Y, Huffman NT, Cui CY, Yao XM, Midura S, Midura RJ, Gorski JP (2009) Confocal laser Raman microspectroscopy of biomineralization foci in UMR 106 osteoblastic cultures reveals temporally synchronized protein changes preceding and accompanying mineral crystal deposition. J Biol Chem 284:7100-7113
    • (2009) J Biol Chem , vol.284 , pp. 7100-7113
    • Wang, C.Y.1    Wang, Y.2    Huffman, N.T.3    Cui, C.Y.4    Yao, X.M.5    Midura, S.6    Midura, R.J.7    Gorski, J.P.8
  • 54
    • 34547872020 scopus 로고    scopus 로고
    • Raman imaging for quantification of the volume fraction of biodegradable polymers in histological preparations
    • DOI 10.1002/jbm.a.31182
    • Nandagawali ST, Yerramshetty JS, Akkus O (2007) Raman imaging for quantification of the volume fraction of biodegradable polymers in histological preparations. J Biomed Mater Res A 82:611-617 (Pubitemid 47258575)
    • (2007) Journal of Biomedical Materials Research - Part A , vol.82 , Issue.3 , pp. 611-617
    • Nandagawali, S.T.1    Yerramshetty, J.S.2    Akkus, O.3
  • 55
    • 39149145476 scopus 로고    scopus 로고
    • The associations between mineral crystallinity and the mechanical properties of human cortical bone
    • Yerramshetty JS, Akkus O (2008) The associations between mineral crystallinity and the mechanical properties of human cortical bone. Bone 42:476-482
    • (2008) Bone , vol.42 , pp. 476-482
    • Yerramshetty, J.S.1    Akkus, O.2
  • 56
    • 33751530439 scopus 로고    scopus 로고
    • The compositional and physicochemical homogeneity of male femoral cortex increases after the sixth decade
    • DOI 10.1016/j.bone.2006.06.002, PII S8756328206005576
    • Yerramshetty JS, Lind C, Akkus O (2006) The compositional and physicochemical homogeneity of male femoral cortex increases after the sixth decade. Bone 39:1236-1243 (Pubitemid 44834503)
    • (2006) Bone , vol.39 , Issue.6 , pp. 1236-1243
    • Yerramshetty, J.S.1    Lind, C.2    Akkus, O.3
  • 57
    • 75749111384 scopus 로고    scopus 로고
    • Effects of tissue age on bone tissue material composition and nanomechanical properties in the rat cortex
    • Donnelly E, Boskey AL, Baker SP, van der Meulen MCH (2010) Effects of tissue age on bone tissue material composition and nanomechanical properties in the rat cortex. J Biomed Mater Res A 92A:1048-1056
    • (2010) J Biomed Mater Res A , vol.92 A , pp. 1048-1056
    • Donnelly, E.1    Boskey, A.L.2    Baker, S.P.3    Van Der Meulen, M.C.H.4
  • 58
    • 0026733404 scopus 로고
    • On the rat model of human osteopenias and osteoporosis
    • Frost HM, Jee WSS (1992) On the rat model of human osteopenias and osteoporosis. Bone Miner 18:227-236
    • (1992) Bone Miner , vol.18 , pp. 227-236
    • Frost, H.M.1    Jee, W.S.S.2
  • 59
    • 34250206639 scopus 로고    scopus 로고
    • Exocytotic process as a novel model for mineralization by osteoblasts in vitro and in vivo determined by electron microscopic analysis
    • DOI 10.1007/s00223-007-9013-5
    • Rohde M, Mayer H (2007) Exocytotic process as a novel model for mineralization by osteoblasts in vitro and in vivo determined by electron microscopic analysis. Calcif Tissue Int 80:323-336 (Pubitemid 46897446)
    • (2007) Calcified Tissue International , vol.80 , Issue.5 , pp. 323-336
    • Rohde, M.1    Mayer, H.2
  • 60
    • 1342302686 scopus 로고    scopus 로고
    • Sex and age related Ca/P ratio in cortical bone of iliac crest of healthy humans
    • DOI 10.1023/B:JRNC.0000017316.20693.45
    • Tzaphlidou M, Zaichick V (2004) Sex and age related Ca/P ratio in cortical bone of iliac crest of healthy humans. J Radioanal Nuclear Chem 259:347-349 (Pubitemid 38250101)
    • (2004) Journal of Radioanalytical and Nuclear Chemistry , vol.259 , Issue.2 , pp. 347-349
    • Tzaphlidou, M.1    Zaichick, V.2
  • 61
    • 0013887585 scopus 로고
    • Microscopic hardness of bone
    • Weaver JK (1966) Microscopic hardness of bone. J Bone Joint Surg Am 48:273-288
    • (1966) J Bone Joint Surg Am , vol.48 , pp. 273-288
    • Weaver, J.K.1
  • 62
    • 35148887758 scopus 로고    scopus 로고
    • The effect of tissue condition and applied load on Vickers hardness of human trabecular bone
    • DOI 10.1016/j.jbiomech.2007.04.007, PII S0021929007001650
    • Dall'Ara E, Ohman C, Baleani M, Viceconti M (2007) The effect of tissue condition and applied load on Vickers hardness of human trabecular bone. J Biomech 40:3267-3270 (Pubitemid 47542325)
    • (2007) Journal of Biomechanics , vol.40 , Issue.14 , pp. 3267-3270
    • Dall'Ara, E.1    Ohman, C.2    Baleani, M.3    Viceconti, M.4
  • 63
    • 0027973996 scopus 로고
    • Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy
    • DOI 10.1002/jcb.240560303
    • Bruder SP, Fink DJ, Caplan AI (1994) Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem 56:283-294 (Pubitemid 24360045)
    • (1994) Journal of Cellular Biochemistry , vol.56 , Issue.3 , pp. 283-294
    • Bruder, S.P.1    Fink, D.J.2    Caplan, A.I.3
  • 64
    • 0026228558 scopus 로고
    • Mesenchymal stem cells
    • Caplan AI (1991) Mesenchymal stem cells. J Orthop Res 9:641-650
    • (1991) J Orthop Res , vol.9 , pp. 641-650
    • Caplan, A.I.1
  • 65
    • 74949112657 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells
    • Ohishi M, Schipani E (2010) Bone marrow mesenchymal stem cells. J Cell Biochem 109:277-282
    • (2010) J Cell Biochem , vol.109 , pp. 277-282
    • Ohishi, M.1    Schipani, E.2
  • 66
    • 33644851676 scopus 로고    scopus 로고
    • Nonadherent cell population of human marrow culture is a complementary source of mesenchymal stem cells (MSCs)
    • DOI 10.1002/jor.20023
    • Wan C, He Q, McCaigue M, Marsh D, Li G (2006) Nonadherent cell population of human marrow culture is a complementary source of mesenchymal stem cells (MSCs). J Orthop Res 24:21-28 (Pubitemid 43772604)
    • (2006) Journal of Orthopaedic Research , vol.24 , Issue.1 , pp. 21-28
    • Wan, C.1    He, Q.2    McCaigue, M.3    Marsh, D.4    Li, G.5
  • 67
    • 0026331350 scopus 로고
    • Ultrastructure of mineralized nodules formed in rat bone-marrow stromal cell culture in vitro
    • Satomura K, Nagayama M (1991) Ultrastructure of mineralized nodules formed in rat bone-marrow stromal cell culture in vitro. Acta Anat 142:97-104
    • (1991) Acta Anat , vol.142 , pp. 97-104
    • Satomura, K.1    Nagayama, M.2
  • 68
    • 0036433359 scopus 로고    scopus 로고
    • Transplanted bone marrow cells localize to fracture callus in a mouse model
    • DOI 10.1016/S0736-0266(02)00051-7, PII S0736026602000517
    • Devine MJ, Mierisch CM, Jang E, Anderson PC, Balian G (2002) Transplanted bone marrow cells localize to fracture callus in a mouse model. J Orthop Res 20:1232-1239 (Pubitemid 35363980)
    • (2002) Journal of Orthopaedic Research , vol.20 , Issue.6 , pp. 1232-1239
    • Devine, M.J.1    Mierisch, C.M.2    Jang, E.3    Anderson, P.C.4    Balian, G.5
  • 70
    • 0035069575 scopus 로고    scopus 로고
    • Age- And gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors
    • DOI 10.1016/S0736-0266(00)00010-3, PII S0736026600000103
    • Muschler GF, Nitto H, Boehm CA, Easley KA (2001) Age- and gender-related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors. J Orthop Res 19:117-125 (Pubitemid 32288644)
    • (2001) Journal of Orthopaedic Research , vol.19 , Issue.1 , pp. 117-125
    • Muschler, G.F.1    Nitto, H.2    Boehm, C.A.3    Easley, K.A.4
  • 71
    • 0014261390 scopus 로고
    • Heterotopic transplants of bone marrow - Analysis of precursor cells for osteogenic and hematopoietic tissues
    • Friedenstein AJ, Petrakov KV, Kuroleso AI, Frolova GP (1968) Heterotopic transplants of bone marrow - analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 6:230-247
    • (1968) Transplantation , vol.6 , pp. 230-247
    • Friedenstein, A.J.1    Petrakov, K.V.2    Kuroleso, A.I.3    Frolova, G.P.4
  • 73
    • 0025903342 scopus 로고
    • Immunolocalization of collagen type I and type III, tenascin, and fibronectin in intramembranous bone
    • Carter DH, Sloan P, Aaron JE (1991) Immunolocalization of collagen type I and type III, tenascin, and fibronectin in intramembranous bone. J Histochem Cytochem 39:599-606
    • (1991) J Histochem Cytochem , vol.39 , pp. 599-606
    • Carter, D.H.1    Sloan, P.2    Aaron, J.E.3
  • 75
    • 0032841147 scopus 로고    scopus 로고
    • Does adult fracture repair recapitulate embryonic skeletal formation?
    • Ferguson C, Alpern E, Miclau T, Helms JA (1999) Does adult fracture repair recapitulate embryonic skeletal formation? Mech Dev 87:57-66
    • (1999) Mech Dev , vol.87 , pp. 57-66
    • Ferguson, C.1    Alpern, E.2    Miclau, T.3    Helms, J.A.4
  • 76
    • 0033662265 scopus 로고    scopus 로고
    • Cranial sutures as intramembranous bone growth sites
    • Opperman LA (2000) Cranial sutures as intramembranous bone growth sites. Dev Dyn 219:472-485
    • (2000) Dev Dyn , vol.219 , pp. 472-485
    • Opperman, L.A.1
  • 77
    • 5344271161 scopus 로고    scopus 로고
    • The relative contribution of cysteine proteinases and matrix metalloproteinases to the resorption process in osteoclasts derived from long bone and scapula
    • DOI 10.1016/j.bone.2004.06.002, PII S8756328204002534
    • Shorey S, Heersche JNM, Manolson MF (2004) The relative contribution of cysteine proteinases and matrix metalloproteinases to the resorption process in osteoclasts derived from long bone and scapula. Bone 35:909-917 (Pubitemid 39349222)
    • (2004) Bone , vol.35 , Issue.4 , pp. 909-917
    • Shorey, S.1    Heersche, J.N.M.2    Manolson, M.F.3
  • 78
    • 0035865852 scopus 로고    scopus 로고
    • Development of the clavicles in birds and mammals
    • Hall BK (2001) Development of the clavicles in birds and mammals. J Exp Zool 289:153-161
    • (2001) J Exp Zool , vol.289 , pp. 153-161
    • Hall, B.K.1
  • 79
    • 33746148506 scopus 로고    scopus 로고
    • Comparison of bone formation ingrafted periosteum harvested from tibia and calvaria
    • DOI 10.1002/jemt.20274
    • Fujii T, Ueno T, Kagawa T, Sakata Y, Sugahara T (2006) Comparison of bone formation ingrafted periosteum harvested from tibia and calvaria. Microsc Res Tech 69:580-584 (Pubitemid 44087207)
    • (2006) Microscopy Research and Technique , vol.69 , Issue.7 , pp. 580-584
    • Fujii, T.1    Ueno, T.2    Kagawa, T.3    Sakata, Y.4    Sugahara, T.5
  • 80
    • 58649117944 scopus 로고    scopus 로고
    • Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration
    • Colnot C (2009) Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration. J Bone Miner Res 24:274-282
    • (2009) J Bone Miner Res , vol.24 , pp. 274-282
    • Colnot, C.1
  • 81
    • 0017815136 scopus 로고
    • Origin of bone marrow stromal mechanocytes in radiochimeras and heterotopic transplants
    • Friedenstein AJ, Ivanovsmolenski AA, Chajlakjan RK, Gorskaya UF, Kuralesova AI, Latzinik NW, Gerasimow UW (1978) Origin of bone-marrow stromal mechanocytes in radiochimeras and heterotopic transplants. Exp Hematol 6:440-444 (Pubitemid 8350843)
    • (1978) Experimental Hematology , vol.6 , Issue.5 , pp. 440-444
    • Friedenstein, A.J.1    Ivanov-Smolenski, A.A.2    Chajlakjan, R.K.3
  • 82
    • 0036462473 scopus 로고    scopus 로고
    • Unravelling novel intracellular pathways in cell-based assays
    • DOI 10.1016/S1359-6446(01)02126-2, PII S1359644602021262
    • Giese K, Kaufmann J, Pronk GJ, Klippel A (2002) Unravelling novel intracellular pathways in cell-based assays. Drug Discov Today 7:179-186 (Pubitemid 34123293)
    • (2002) Drug Discovery Today , vol.7 , Issue.3 , pp. 179-186
    • Giese, K.1    Kaufmann, J.2    Pronk, G.J.3    Klippel, A.4


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