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Volumn 89, Issue 7, 2011, Pages 969-978

Vascular endothelial growth factor in cerebral ischemia

Author keywords

Angiogenesis; Neurogenesis; Neuroprotection; Stroke; VEGF

Indexed keywords

ANGIOPOIETIN 1; VASCULOTROPIN; VASCULOTROPIN RECEPTOR;

EID: 79955623913     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22628     Document Type: Review
Times cited : (34)

References (93)
  • 1
    • 20444477494 scopus 로고    scopus 로고
    • Aggravation of hemorrhagic transformation by early intraarterial infusion of low-dose vascular endothelial growth factor after transient focal cerebral ischemia in rats
    • Abumiya T, Yokota C, Kuge Y, Minematsu K. 2005. Aggravation of hemorrhagic transformation by early intraarterial infusion of low-dose vascular endothelial growth factor after transient focal cerebral ischemia in rats. Brain Res 1049: 95-103.
    • (2005) Brain Res , vol.1049 , pp. 95-103
    • Abumiya, T.1    Yokota, C.2    Kuge, Y.3    Minematsu, K.4
  • 2
    • 60649108674 scopus 로고    scopus 로고
    • VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
    • Argaw AT, Gurfein BT, Zhang Y, Zameer A, John GR. 2009. VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown. Proc Natl Acad Sci U S A 106: 1977-1882.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1977-1882
    • Argaw, A.T.1    Gurfein, B.T.2    Zhang, Y.3    Zameer, A.4    John, G.R.5
  • 3
    • 64449086483 scopus 로고    scopus 로고
    • Angiogenesis after cerebral ischemia
    • Beck H, Plate KH. 2009. Angiogenesis after cerebral ischemia. Acta Neuropathol 117: 481-496.
    • (2009) Acta Neuropathol , vol.117 , pp. 481-496
    • Beck, H.1    Plate, K.H.2
  • 5
    • 0035933126 scopus 로고    scopus 로고
    • Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF
    • Cao R, Brakenhielm E, Wahlestedt C, Thyberg J, Cao Y. 2001. Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF. Proc Natl Acad Sci U S A 98: 6390-6395.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 6390-6395
    • Cao, R.1    Brakenhielm, E.2    Wahlestedt, C.3    Thyberg, J.4    Cao, Y.5
  • 6
    • 0041378074 scopus 로고    scopus 로고
    • Blood vessels and nerves: common signals, pathways and diseases
    • Carmeliet P. 2003. Blood vessels and nerves: common signals, pathways and diseases. Nat Rev Genet 4: 710-720.
    • (2003) Nat Rev Genet , vol.4 , pp. 710-720
    • Carmeliet, P.1
  • 7
    • 0342872023 scopus 로고    scopus 로고
    • Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
    • Chen H, Chedotal A, He Z, Goodman CS, Tessier-Lavigne M. 1997. Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III. Neuron 19: 547-559.
    • (1997) Neuron , vol.19 , pp. 547-559
    • Chen, H.1    Chedotal, A.2    He, Z.3    Goodman, C.S.4    Tessier-Lavigne, M.5
  • 8
    • 33847332493 scopus 로고    scopus 로고
    • Effects of anti-VEGF antibody on blood-brain barrier disruption in focal cerebral ischemia
    • Chi OZ, Hunter C, Liu X, Weiss HR. 2007. Effects of anti-VEGF antibody on blood-brain barrier disruption in focal cerebral ischemia. Exp Neurol 204: 283-287.
    • (2007) Exp Neurol , vol.204 , pp. 283-287
    • Chi, O.Z.1    Hunter, C.2    Liu, X.3    Weiss, H.R.4
  • 11
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
    • Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. 1999. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell 4: 915-924.
    • (1999) Mol Cell , vol.4 , pp. 915-924
    • Eliceiri, B.P.1    Paul, R.2    Schwartzberg, P.L.3    Hood, J.D.4    Leng, J.5    Cheresh, D.A.6
  • 12
    • 77549088772 scopus 로고    scopus 로고
    • Pathways mediating VEGF-independent tumor angiogenesis
    • Ferrara N. 2010. Pathways mediating VEGF-independent tumor angiogenesis. Cytokine Growth Factor Rev 21: 21-26.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 21-26
    • Ferrara, N.1
  • 13
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. 2003. The biology of VEGF and its receptors. Nat Med 9: 669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 15
    • 0035964880 scopus 로고    scopus 로고
    • Expressions of neuropilin-1, neuropilin-2 and semaphorin 3A mRNA in the rat brain after middle cerebral artery occlusion
    • Fujita H, Zhang B, Sato K, Tanaka J, Sakanaka M. 2001. Expressions of neuropilin-1, neuropilin-2 and semaphorin 3A mRNA in the rat brain after middle cerebral artery occlusion. Brain Res 914: 1-14.
    • (2001) Brain Res , vol.914 , pp. 1-14
    • Fujita, H.1    Zhang, B.2    Sato, K.3    Tanaka, J.4    Sakanaka, M.5
  • 16
    • 70350561897 scopus 로고    scopus 로고
    • Attenuation of brain response to vascular endothelial growth factor-mediated angiogenesis and neurogenesis in aged mice
    • Gao P, Shen F, Gabriel RA, Law D, Yang E, Yang GY, Young WL, Su H. 2009. Attenuation of brain response to vascular endothelial growth factor-mediated angiogenesis and neurogenesis in aged mice. Stroke 40: 3596-3600.
    • (2009) Stroke , vol.40 , pp. 3596-3600
    • Gao, P.1    Shen, F.2    Gabriel, R.A.3    Law, D.4    Yang, E.5    Yang, G.Y.6    Young, W.L.7    Su, H.8
  • 17
    • 41049099329 scopus 로고    scopus 로고
    • Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis
    • Geretti E, Shimizu A, Klagsbrun M. 2008. Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis 11: 31-39.
    • (2008) Angiogenesis , vol.11 , pp. 31-39
    • Geretti, E.1    Shimizu, A.2    Klagsbrun, M.3
  • 18
    • 67949115400 scopus 로고    scopus 로고
    • Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis
    • Ha CH, Jin ZG. 2009. Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis. Mol Cells 28: 1-5.
    • (2009) Mol Cells , vol.28 , pp. 1-5
    • Ha, C.H.1    Jin, Z.G.2
  • 19
    • 0141529716 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression and angiogenesis induced by chronic cerebral hypoperfusion in rat brain
    • discussion 970-972.
    • Hai J, Li ST, Lin Q, Pan QG, Gao F, Ding MX. 2003. Vascular endothelial growth factor expression and angiogenesis induced by chronic cerebral hypoperfusion in rat brain. Neurosurgery 53: 963-970; discussion 970-972.
    • (2003) Neurosurgery , vol.53 , pp. 963-970
    • Hai, J.1    Li, S.T.2    Lin, Q.3    Pan, Q.G.4    Gao, F.5    Ding, M.X.6
  • 20
    • 0036524018 scopus 로고    scopus 로고
    • Intraventricular infusion of vascular endothelial growth factor promotes cerebral angiogenesis with minimal brain edema
    • Harrigan MR, Ennis SR, Masada T, Keep RF. 2002. Intraventricular infusion of vascular endothelial growth factor promotes cerebral angiogenesis with minimal brain edema. Neurosurgery 50: 589-598.
    • (2002) Neurosurgery , vol.50 , pp. 589-598
    • Harrigan, M.R.1    Ennis, S.R.2    Masada, T.3    Keep, R.F.4
  • 21
    • 0037266459 scopus 로고    scopus 로고
    • Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume
    • Harrigan MR, Ennis SR, Sullivan SE, Keep RF. 2003. Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume. Acta Neurochir 145: 49-53.
    • (2003) Acta Neurochir , vol.145 , pp. 49-53
    • Harrigan, M.R.1    Ennis, S.R.2    Sullivan, S.E.3    Keep, R.F.4
  • 22
    • 0031826273 scopus 로고    scopus 로고
    • Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia
    • Hayashi T, Abe K, Itoyama Y. 1998. Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia. J Cereb Blood Flow Metab 18: 887-895.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 887-895
    • Hayashi, T.1    Abe, K.2    Itoyama, Y.3
  • 23
    • 0030847193 scopus 로고    scopus 로고
    • Neuropilin is a receptor for the axonal chemorepellent semaphorin III
    • He Z, Tessier-Lavigne M. 1997. Neuropilin is a receptor for the axonal chemorepellent semaphorin III. Cell 90: 739-751.
    • (1997) Cell , vol.90 , pp. 739-751
    • He, Z.1    Tessier-Lavigne, M.2
  • 24
    • 70349675503 scopus 로고    scopus 로고
    • Implications of vascular endothelial growth factor for postischemic neurovascular remodeling
    • Hermann DM, Zechariah A. 2009. Implications of vascular endothelial growth factor for postischemic neurovascular remodeling. J Cereb Blood Flow Metab 29: 1620-1643.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1620-1643
    • Hermann, D.M.1    Zechariah, A.2
  • 25
    • 0027064888 scopus 로고
    • Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
    • Houck KA, Leung DW, Rowland AM, Winer J, Ferrara N. 1992. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J Biol Chem 267: 26031-26037.
    • (1992) J Biol Chem , vol.267 , pp. 26031-26037
    • Houck, K.A.1    Leung, D.W.2    Rowland, A.M.3    Winer, J.4    Ferrara, N.5
  • 27
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia
    • Jin KL, Mao XO, Greenberg DA. 2000. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc Natl Acad Sci U S A 97: 10242-10247.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 28
    • 0035842544 scopus 로고    scopus 로고
    • Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor
    • Jin K, Mao XO, Batteur SP, McEachron E, Leahy A, Greenberg DA. 2001a. Caspase-3 and the regulation of hypoxic neuronal death by vascular endothelial growth factor. Neuroscience 108: 351-38.
    • (2001) Neuroscience , vol.108 , pp. 351-338
    • Jin, K.1    Mao, X.O.2    Batteur, S.P.3    McEachron, E.4    Leahy, A.5    Greenberg, D.A.6
  • 29
    • 0035836656 scopus 로고    scopus 로고
    • Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
    • Jin K, Minami M, Lan JQ, Mao XO, Batteur S, Simon RP, Greenberg DA. 2001b. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A 98: 4710-4715.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4710-4715
    • Jin, K.1    Minami, M.2    Lan, J.Q.3    Mao, X.O.4    Batteur, S.5    Simon, R.P.6    Greenberg, D.A.7
  • 30
    • 0037015059 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
    • Jin K, Zhu Y, Sun Y, Mao XO, Xie L, Greenberg DA. 2002. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci U S A 99: 11946-11950.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11946-11950
    • Jin, K.1    Zhu, Y.2    Sun, Y.3    Mao, X.O.4    Xie, L.5    Greenberg, D.A.6
  • 33
    • 24944471398 scopus 로고    scopus 로고
    • VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly
    • Kaya D, Gursoy-Ozdemir Y, Yemisci M, Tuncer N, Aktan S, Dalkara T. 2005. VEGF protects brain against focal ischemia without increasing blood-brain permeability when administered intracerebroventricularly. J Cereb Blood Flow Metab 25: 1111-1118.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1111-1118
    • Kaya, D.1    Gursoy-Ozdemir, Y.2    Yemisci, M.3    Tuncer, N.4    Aktan, S.5    Dalkara, T.6
  • 35
    • 33845666847 scopus 로고    scopus 로고
    • The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood-brain barrier permeability after focal cerebral ischemia
    • Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM. 2006a. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood-brain barrier permeability after focal cerebral ischemia. FASEB J 20: 1185-1187.
    • (2006) FASEB J , vol.20 , pp. 1185-1187
    • Kilic, E.1    Kilic, U.2    Wang, Y.3    Bassetti, C.L.4    Marti, H.H.5    Hermann, D.M.6
  • 36
  • 37
    • 20444416673 scopus 로고    scopus 로고
    • Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction
    • Kimura R, Nakase H, Tamaki R, Sakaki T. 2005. Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction. Stroke 36: 1259-1263.
    • (2005) Stroke , vol.36 , pp. 1259-1263
    • Kimura, R.1    Nakase, H.2    Tamaki, R.3    Sakaki, T.4
  • 38
    • 77956621126 scopus 로고    scopus 로고
    • The novel VEGF receptor antagonist, VGA1155, reduces edema, decreases infarct and improves neurological function after stroke in rats
    • Koyama J, Miyake S, Sasayama T, Chiba Y, Kondoh T, Kohmura E. 2010. The novel VEGF receptor antagonist, VGA1155, reduces edema, decreases infarct and improves neurological function after stroke in rats. Kobe J Med Sci 56: E1-E11.
    • (2010) Kobe J Med Sci , vol.56
    • Koyama, J.1    Miyake, S.2    Sasayama, T.3    Chiba, Y.4    Kondoh, T.5    Kohmura, E.6
  • 39
    • 0027936452 scopus 로고
    • Role of angiogenesis in patients with cerebral ischemic stroke
    • Krupinski J, Kaluza J, Kumar P, Kumar S, Wang JM. 1994. Role of angiogenesis in patients with cerebral ischemic stroke. Stroke 25: 1794-1798.
    • (1994) Stroke , vol.25 , pp. 1794-1798
    • Krupinski, J.1    Kaluza, J.2    Kumar, P.3    Kumar, S.4    Wang, J.M.5
  • 41
    • 65549161030 scopus 로고    scopus 로고
    • VEGF-A/VEGFR-2 signaling leading to cAMP response element-binding protein phosphorylation is a shared pathway underlying the protective effect of preconditioning on neurons and endothelial cells
    • Lee HT, Chang YC, Tu YF, Huang CC. 2009. VEGF-A/VEGFR-2 signaling leading to cAMP response element-binding protein phosphorylation is a shared pathway underlying the protective effect of preconditioning on neurons and endothelial cells. J Neurosci 29: 4356-4368.
    • (2009) J Neurosci , vol.29 , pp. 4356-4368
    • Lee, H.T.1    Chang, Y.C.2    Tu, Y.F.3    Huang, C.C.4
  • 42
    • 77749264878 scopus 로고    scopus 로고
    • CREB activation mediates VEGF-A's protection of neurons and cerebral vascular endothelial cells
    • Lee HT, Chang YC, Tu YF, Huang CC. 2010. CREB activation mediates VEGF-A's protection of neurons and cerebral vascular endothelial cells. J Neurochem 113: 79-91.
    • (2010) J Neurochem , vol.113 , pp. 79-91
    • Lee, H.T.1    Chang, Y.C.2    Tu, Y.F.3    Huang, C.C.4
  • 43
    • 0031683937 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat
    • Lennmyr F, Ata KA, Funa K, Olsson Y, Terent A. 1998. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat. J Neuropathol Exp Neurol 57: 874-882.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 874-882
    • Lennmyr, F.1    Ata, K.A.2    Funa, K.3    Olsson, Y.4    Terent, A.5
  • 44
    • 16844366785 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene expression in middle cerebral artery occlusion in the rat
    • Lennmyr F, Terent A, Syvanen AC, Barbany G. 2005. Vascular endothelial growth factor gene expression in middle cerebral artery occlusion in the rat. Acta Anaesthesiol Scand 49: 488-493.
    • (2005) Acta Anaesthesiol Scand , vol.49 , pp. 488-493
    • Lennmyr, F.1    Terent, A.2    Syvanen, A.C.3    Barbany, G.4
  • 45
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. 1989. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 46
    • 70349747308 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus serotype 1-vascular endothelial growth factor promotes neurogenesis and neuromigration in the subventricular zone and rescues neuronal function in ischemic rats
    • discussion 779.
    • Li SF, Sun YB, Meng QH, Li SR, Yao WC, Hu GJ, Li ZJ, Wang RZ. 2009. Recombinant adeno-associated virus serotype 1-vascular endothelial growth factor promotes neurogenesis and neuromigration in the subventricular zone and rescues neuronal function in ischemic rats. Neurosurgery 65: 771-779; discussion 779.
    • (2009) Neurosurgery , vol.65 , pp. 771-779
    • Li, S.F.1    Sun, Y.B.2    Meng, Q.H.3    Li, S.R.4    Yao, W.C.5    Hu, G.J.6    Li, Z.J.7    Wang, R.Z.8
  • 47
    • 0027263738 scopus 로고
    • Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity
    • Maiese K, Boniece I, DeMeo D, Wagner JA. 1993. Peptide growth factors protect against ischemia in culture by preventing nitric oxide toxicity. J Neurosci 13: 3034-3040.
    • (1993) J Neurosci , vol.13 , pp. 3034-3040
    • Maiese, K.1    Boniece, I.2    DeMeo, D.3    Wagner, J.A.4
  • 48
    • 2642569472 scopus 로고    scopus 로고
    • Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis
    • Manoonkitiwongsa PS, Schultz RL, McCreery DB, Whitter EF, Lyden PD. 2004. Neuroprotection of ischemic brain by vascular endothelial growth factor is critically dependent on proper dosage and may be compromised by angiogenesis. J Cereb Blood Flow Metab 24: 693-702.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 693-702
    • Manoonkitiwongsa, P.S.1    Schultz, R.L.2    McCreery, D.B.3    Whitter, E.F.4    Lyden, P.D.5
  • 49
    • 0032431037 scopus 로고    scopus 로고
    • Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
    • Marti HH, Risau W. 1998. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci U S A 95: 15809-15814.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15809-15814
    • Marti, H.H.1    Risau, W.2
  • 50
    • 0033902012 scopus 로고    scopus 로고
    • Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia
    • Marti HJ, Bernaudin M, Bellail A, Schoch H, Euler M, Petit E, Risau W. 2000. Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia. Am J Pathol 156: 965-976.
    • (2000) Am J Pathol , vol.156 , pp. 965-976
    • Marti, H.J.1    Bernaudin, M.2    Bellail, A.3    Schoch, H.4    Euler, M.5    Petit, E.6    Risau, W.7
  • 51
    • 0033028795 scopus 로고    scopus 로고
    • VEGF increases permeability of the blood-brain barrier via a nitric oxide synthase/cGMP-dependent pathway
    • Mayhan WG. 1999. VEGF increases permeability of the blood-brain barrier via a nitric oxide synthase/cGMP-dependent pathway. Am J Physiol 276: C1148-C1153.
    • (1999) Am J Physiol , vol.276
    • Mayhan, W.G.1
  • 52
    • 34548845327 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene-transferred bone marrow stromal cells engineered with a herpes simplex virus type 1 vector can improve neurological deficits and reduce infarction volume in rat brain ischemia
    • discussion 594-595.
    • Miki Y, Nonoguchi N, Ikeda N, Coffin RS, Kuroiwa T, Miyatake S. 2007. Vascular endothelial growth factor gene-transferred bone marrow stromal cells engineered with a herpes simplex virus type 1 vector can improve neurological deficits and reduce infarction volume in rat brain ischemia. Neurosurgery 61: 586-594; discussion 594-595.
    • (2007) Neurosurgery , vol.61 , pp. 586-594
    • Miki, Y.1    Nonoguchi, N.2    Ikeda, N.3    Coffin, R.S.4    Kuroiwa, T.5    Miyatake, S.6
  • 53
    • 0027461981 scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues
    • Monacci WT, Merrill MJ, Oldfield EH. 1993. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am J Physiol 264: C995-C1002.
    • (1993) Am J Physiol , vol.264
    • Monacci, W.T.1    Merrill, M.J.2    Oldfield, E.H.3
  • 55
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. 1999. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13: 9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 56
    • 0032963472 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
    • Nor JE, Christensen J, Mooney DJ, Polverini PJ. 1999. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 154: 375-384.
    • (1999) Am J Pathol , vol.154 , pp. 375-384
    • Nor, J.E.1    Christensen, J.2    Mooney, D.J.3    Polverini, P.J.4
  • 57
    • 0027751890 scopus 로고
    • The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
    • Park JE, Keller GA, Ferrara N. 1993. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol Biol Cell 4: 1317-1326.
    • (1993) Mol Biol Cell , vol.4 , pp. 1317-1326
    • Park, J.E.1    Keller, G.A.2    Ferrara, N.3
  • 59
    • 56349164145 scopus 로고    scopus 로고
    • VEGF overexpression improves mice cognitive abilities after unilateral common carotid artery occlusion
    • Plaschke K, Staub J, Ernst E, Marti HH. 2008. VEGF overexpression improves mice cognitive abilities after unilateral common carotid artery occlusion. Exp Neurol 214: 285-292.
    • (2008) Exp Neurol , vol.214 , pp. 285-292
    • Plaschke, K.1    Staub, J.2    Ernst, E.3    Marti, H.H.4
  • 60
    • 65249126363 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats
    • Ploughman M, Windle V, MacLellan CL, White N, Dore JJ, Corbett D. 2009. Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats. Stroke 40: 1490-1495.
    • (2009) Stroke , vol.40 , pp. 1490-1495
    • Ploughman, M.1    Windle, V.2    MacLellan, C.L.3    White, N.4    Dore, J.J.5    Corbett, D.6
  • 61
    • 33845934175 scopus 로고    scopus 로고
    • Requirement of protein kinase D tyrosine phosphorylation for VEGF-A165-induced angiogenesis through its interaction and regulation of phospholipase Cgamma phosphorylation
    • Qin L, Zeng H, Zhao D. 2006. Requirement of protein kinase D tyrosine phosphorylation for VEGF-A165-induced angiogenesis through its interaction and regulation of phospholipase Cgamma phosphorylation. J Biol Chem 281: 32550-32558.
    • (2006) J Biol Chem , vol.281 , pp. 32550-32558
    • Qin, L.1    Zeng, H.2    Zhao, D.3
  • 62
    • 50849120002 scopus 로고    scopus 로고
    • VEGF receptor protein-tyrosine kinases: structure and regulation
    • Roskoski RJr. 2008. VEGF receptor protein-tyrosine kinases: structure and regulation. Biochem Biophys Res Commun 375: 287-291.
    • (2008) Biochem Biophys Res Commun , vol.375 , pp. 287-291
    • Roskoski Jr, R.1
  • 63
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. 1983. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219: 983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 65
    • 33749040234 scopus 로고    scopus 로고
    • Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice
    • Shen F, Su H, Fan Y, Chen Y, Zhu Y, Liu W, Young WL, Yang GY. 2006. Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice. Stroke 37: 2601-2606.
    • (2006) Stroke , vol.37 , pp. 2601-2606
    • Shen, F.1    Su, H.2    Fan, Y.3    Chen, Y.4    Zhu, Y.5    Liu, W.6    Young, W.L.7    Yang, G.Y.8
  • 66
    • 54149116064 scopus 로고    scopus 로고
    • Differential regulation of vascular endothelial growth factor-C and its receptor in the rat hippocampus following transient forebrain ischemia
    • Shin YJ, Choi JS, Lee JY, Choi JY, Cha JH, Chun MH, Lee MY. 2008. Differential regulation of vascular endothelial growth factor-C and its receptor in the rat hippocampus following transient forebrain ischemia. Acta Neuropathol 116: 517-527.
    • (2008) Acta Neuropathol , vol.116 , pp. 517-527
    • Shin, Y.J.1    Choi, J.S.2    Lee, J.Y.3    Choi, J.Y.4    Cha, J.H.5    Chun, M.H.6    Lee, M.Y.7
  • 67
    • 72749092364 scopus 로고    scopus 로고
    • Enhanced expression of vascular endothelial growth factor receptor-3 in the subventricular zone of stroke-lesioned rats
    • Shin YJ, Choi JS, Choi JY, Cha JH, Chun MH, Lee MY. 2010. Enhanced expression of vascular endothelial growth factor receptor-3 in the subventricular zone of stroke-lesioned rats. Neurosci Lett 469: 194-198.
    • (2010) Neurosci Lett , vol.469 , pp. 194-198
    • Shin, Y.J.1    Choi, J.S.2    Choi, J.Y.3    Cha, J.H.4    Chun, M.H.5    Lee, M.Y.6
  • 68
    • 33847343054 scopus 로고    scopus 로고
    • Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor
    • Shraga-Heled N, Kessler O, Prahst C, Kroll J, Augustin H, Neufeld G. 2007. Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor. FASEB J 21: 915-926.
    • (2007) FASEB J , vol.21 , pp. 915-926
    • Shraga-Heled, N.1    Kessler, O.2    Prahst, C.3    Kroll, J.4    Augustin, H.5    Neufeld, G.6
  • 71
    • 0041743159 scopus 로고    scopus 로고
    • VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
    • Sun Y, Jin K, Xie L, Childs J, Mao XO, Logvinova A, Greenberg DA. 2003. VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia. J Clin Invest 111: 1843-1851.
    • (2003) J Clin Invest , vol.111 , pp. 1843-1851
    • Sun, Y.1    Jin, K.2    Xie, L.3    Childs, J.4    Mao, X.O.5    Logvinova, A.6    Greenberg, D.A.7
  • 72
    • 30044451865 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: evidence from knockout mice and growth factor administration
    • Sun Y, Jin K, Childs JT, Xie L, Mao XO, Greenberg DA. 2006. Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: evidence from knockout mice and growth factor administration. Dev Biol 289: 329-335.
    • (2006) Dev Biol , vol.289 , pp. 329-335
    • Sun, Y.1    Jin, K.2    Childs, J.T.3    Xie, L.4    Mao, X.O.5    Greenberg, D.A.6
  • 74
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC, Abraham JA. 1991. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 266: 11947-11954.
    • (1991) J Biol Chem , vol.266 , pp. 11947-11954
    • Tischer, E.1    Mitchell, R.2    Hartman, T.3    Silva, M.4    Gospodarowicz, D.5    Fiddes, J.C.6    Abraham, J.A.7
  • 75
    • 58149381563 scopus 로고    scopus 로고
    • Enhanced adult neurogenesis and angiogenesis and altered affective behaviors in mice overexpressing vascular endothelial growth factor 120
    • Udo H, Yoshida Y, Kino T, Ohnuki K, Mizunoya W, Mukuda T, Sugiyama H. 2008. Enhanced adult neurogenesis and angiogenesis and altered affective behaviors in mice overexpressing vascular endothelial growth factor 120. J Neurosci 28: 14522-14536.
    • (2008) J Neurosci , vol.28 , pp. 14522-14536
    • Udo, H.1    Yoshida, Y.2    Kino, T.3    Ohnuki, K.4    Mizunoya, W.5    Mukuda, T.6    Sugiyama, H.7
  • 79
    • 4844226728 scopus 로고    scopus 로고
    • Alterations in angiogenic growth factors and neuronal nitric oxide synthase expression in chronic cavernosal ischemia
    • Wang T, Soker S, Atala A, Siroky MB, Azadzoi KM. 2004. Alterations in angiogenic growth factors and neuronal nitric oxide synthase expression in chronic cavernosal ischemia. Int J Impot Res 16: 403-411.
    • (2004) Int J Impot Res , vol.16 , pp. 403-411
    • Wang, T.1    Soker, S.2    Atala, A.3    Siroky, M.B.4    Azadzoi, K.M.5
  • 80
    • 11244276997 scopus 로고    scopus 로고
    • VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
    • Wang Y, Kilic E, Kilic U, Weber B, Bassetti CL, Marti HH, Hermann DM. 2005. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain 128: 52-163.
    • (2005) Brain , vol.128 , pp. 52-163
    • Wang, Y.1    Kilic, E.2    Kilic, U.3    Weber, B.4    Bassetti, C.L.5    Marti, H.H.6    Hermann, D.M.7
  • 81
    • 33947205165 scopus 로고    scopus 로고
    • VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration
    • Wang Y, Jin K, Mao XO, Xie L, Banwait S, Marti HH, Greenberg DA. 2007a. VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration. J Neurosci Res 85: 740-747.
    • (2007) J Neurosci Res , vol.85 , pp. 740-747
    • Wang, Y.1    Jin, K.2    Mao, X.O.3    Xie, L.4    Banwait, S.5    Marti, H.H.6    Greenberg, D.A.7
  • 82
    • 33846135022 scopus 로고    scopus 로고
    • VEGF overexpression enhances striatal neurogenesis in brain of adult rat after a transient middle cerebral artery occlusion
    • Wang YQ, Guo X, Qiu MH, Feng XY, Sun FY. 2007b. VEGF overexpression enhances striatal neurogenesis in brain of adult rat after a transient middle cerebral artery occlusion. J Neurosci Res 85: 73-82.
    • (2007) J Neurosci Res , vol.85 , pp. 73-82
    • Wang, Y.Q.1    Guo, X.2    Qiu, M.H.3    Feng, X.Y.4    Sun, F.Y.5
  • 83
    • 69549127954 scopus 로고    scopus 로고
    • VEGF enhance cortical newborn neurons and their neurite development in adult rat brain after cerebral ischemia
    • Wang YQ, Cui HR, Yang SZ, Sun HP, Qiu MH, Feng XY, Sun FY. 2009. VEGF enhance cortical newborn neurons and their neurite development in adult rat brain after cerebral ischemia. Neurochem Int 55: 629-636.
    • (2009) Neurochem Int , vol.55 , pp. 629-636
    • Wang, Y.Q.1    Cui, H.R.2    Yang, S.Z.3    Sun, H.P.4    Qiu, M.H.5    Feng, X.Y.6    Sun, F.Y.7
  • 84
    • 67650487559 scopus 로고    scopus 로고
    • VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo
    • Wittko IM, Schanzer A, Kuzmichev A, Schneider FT, Shibuya M, Raab S, Plate KH. 2009. VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo. J Neurosci 29: 8704-8714.
    • (2009) J Neurosci , vol.29 , pp. 8704-8714
    • Wittko, I.M.1    Schanzer, A.2    Kuzmichev, A.3    Schneider, F.T.4    Shibuya, M.5    Raab, S.6    Plate, K.H.7
  • 85
    • 25844484590 scopus 로고    scopus 로고
    • Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor
    • Wong C, Jin ZG. 2005. Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor. J Biol Chem 280: 33262-33269.
    • (2005) J Biol Chem , vol.280 , pp. 33262-33269
    • Wong, C.1    Jin, Z.G.2
  • 87
    • 27844508565 scopus 로고    scopus 로고
    • Neuroprotective role of vascular endothelial growth factor: signalling mechanisms, biological function, and therapeutic potential
    • Zachary I. 2005. Neuroprotective role of vascular endothelial growth factor: signalling mechanisms, biological function, and therapeutic potential. Neurosignals 14: 207-221.
    • (2005) Neurosignals , vol.14 , pp. 207-221
    • Zachary, I.1
  • 89
    • 0035004385 scopus 로고    scopus 로고
    • Up-regulation of neuropilin-1 in neovasculature after focal cerebral ischemia in the adult rat
    • Zhang ZG, Tsang W, Zhang L, Powers C, Chopp M. 2001. Up-regulation of neuropilin-1 in neovasculature after focal cerebral ischemia in the adult rat. J Cereb Blood Flow Metab 21: 541-549.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 541-549
    • Zhang, Z.G.1    Tsang, W.2    Zhang, L.3    Powers, C.4    Chopp, M.5
  • 91
    • 77955635526 scopus 로고    scopus 로고
    • Angiopoietin 1 counteracts vascular endothelial growth factor-induced blood-brain barrier permeability and alleviates ischemic injury in the early stages of transient focal cerebral ischemia in rats
    • Zhao Y, Li Z, Wang R, Wei J, Li G, Zhao H. 2010. Angiopoietin 1 counteracts vascular endothelial growth factor-induced blood-brain barrier permeability and alleviates ischemic injury in the early stages of transient focal cerebral ischemia in rats. Neurol Res 32: 748-755.
    • (2010) Neurol Res , vol.32 , pp. 748-755
    • Zhao, Y.1    Li, Z.2    Wang, R.3    Wei, J.4    Li, G.5    Zhao, H.6
  • 92
    • 0037308174 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression
    • Zhu Y, Jin K, Mao XO, Greenberg DA. 2003. Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression. FASEB J 17: 186-193.
    • (2003) FASEB J , vol.17 , pp. 186-193
    • Zhu, Y.1    Jin, K.2    Mao, X.O.3    Greenberg, D.A.4
  • 93
    • 22044443420 scopus 로고    scopus 로고
    • Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain
    • Zhu Y, Lee C, Shen F, Du R, Young WL, Yang GY. 2005. Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain. Stroke 36: 1533-1537.
    • (2005) Stroke , vol.36 , pp. 1533-1537
    • Zhu, Y.1    Lee, C.2    Shen, F.3    Du, R.4    Young, W.L.5    Yang, G.Y.6


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