GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis

Pharmaceutical Research

Volumn 28, Issue 4, 2011, Pages 752-761

  Yang, Ningning ^a   Mahato, Ram I ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

GFAP promoter; liver fibrosis; pri miRNA mimics; shRNA; TGF 1

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; MICRORNA; PLASMID VECTOR; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL SPECIFICITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; RNA SEQUENCE; STELLATE CELL;

ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; GENE THERAPY; GLIAL FIBRILLARY ACIDIC PROTEIN; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MICRORNAS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PLASMIDS; PROMOTER REGIONS, GENETIC; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 79955602304     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0384-y     Document Type: Article

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