Antagonistic TSC22D1 variants control BRAFE600-induced senescence

EMBO Journal

Volumn 30, Issue 9, 2011, Pages 1753-1765

  Hömig Hölzel, Cornelia ^a   Van Doorn, Remco ^a,c   Vogel, Celia ^a   Germann, Markus ^b   Cecchini, Marco G ^b   Verdegaal, Els ^c   Peeper, Daniel S ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY OF BERN   (Switzerland)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

C EBP ; oncogene induced senescence; THG1; TSC22; TSC22D1

Indexed keywords

B RAF KINASE; BETA ACTIN; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GENE PRODUCT; PROTEASOME; PROTEIN BRAF E600; PROTEIN THG1; PROTEIN TSC22D1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIMERIZATION; FIBROBLAST; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MELANOCYTE; ONCOGENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN VARIANT; SENESCENCE; SIGNAL TRANSDUCTION; TSC22D1 GENE; TUMOR SUPPRESSOR GENE; UPREGULATION;

CELL AGING; DNA PRIMERS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; MELANOCYTES; MICROARRAY ANALYSIS; PLASMIDS; PROTO-ONCOGENE PROTEINS B-RAF; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 79955594663     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.95     Document Type: Article

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