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Volumn 46, Issue 6, 2011, Pages 2152-2156

Chemoenzymatic synthesis with lipase catalyzed resolution and evaluation of antitumor activity of (R/S)-2-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propyl]-1H- pyrrolo[3,4-b]quinolin-3(2H)-one

(4) Nagarapu, Lingaiah a Gaikwad, Hanmant K a Bantu, Rajashaker a Manikonda, Sheeba Rani a

a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (India)

Author keywords

Cytotoxicity; Lipase; Lung carcinoma A549 cell line; Neuroblastoma cell line (SK N SH)

Indexed keywords

2 [2 HYDROXY 3 (4 PHENYLPIPERAZIN 1 YL)PROPYL] 1H PYRROLO[3,4 B]QUINOLIN 3(2H) ONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANDIDA ANTARCTICA; CANDIDA RUGOSA; CATALYSIS; DRUG SCREENING; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; NEUROBLASTOMA;

ANTINEOPLASTIC AGENTS; BIOCATALYSIS; CANDIDA; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LIPASE; MOLECULAR STRUCTURE; PIPERAZINES; QUINOLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955591133 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.02.069 Document Type: Article

Times cited : (44)

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