Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 3, 2008, Pages 1167-1171

  Nagarapu, Lingaiah ^a   Satyender, A ^a   Rajashaker, B ^a   Srinivas, K ^a   rani, P Rupa ^a   Radhika, K ^a   Subhashini, G ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Bioactive; C 2 chiral polyhydroxy imidazoles; Potassium dodecatungstocobaltate trihydrate

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; GLYCOCONJUGATE; IMIDAZOLE DERIVATIVE; PENICILLIN G; STREPTOMYCIN;

ANALYTIC METHOD; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; CANDIDA ALBICANS; DRUG SYNTHESIS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; RHIZOPUS ORYZAE; SACCHAROMYCES CEREVISIAE; SPECTROSCOPY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIA; COMBINATORIAL CHEMISTRY TECHNIQUES; GLYCOCONJUGATES; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PSEUDOMONAS AERUGINOSA;

EID: 38849199233     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.118     Document Type: Article

References (17)

1. Grammitt M.R., Katrizky A.R., and Boulton A.J. Advances in Heterocyclic Chemistry Vol. 27 (1989), Academic, New York 241
2. Grammitt M.R., Katrizky A.R., and Boulton A.J. Advances in Heterocyclic Chemistry Vol. 12 (1970), Academic, New York 103
3. Aoyagi T., Suda H., Uotani K., Kojima F., Aoyama T., Horiguchi K., Hamada M., and Takeuchi T. J. Antibiot. 45 (1992) 1404
4. Aoyama T., Naganawa N.H., Suda H., Uotani K., Aoyagi T., and Takeuchi T. J. Antibiot. 45 (1992) 1557
5. Heightman H., and Vasella T. Angew. Chem. Int. Ed. 38 (1999) 750
6. Tatsuta K., Miura S., Ohta S., and Gunji H. J. Antibiot. 48 (1995) 286
7. Sinnott M.L. Chem. Rev (1990) 1171
8. In: Varki A., Cummings R., Esko J., Freeze H., Hart G., and Marth J. (Eds). Essentials of Glycobiology (1993), Cold Spring Harbor Laboratory Press, New York
9. Varki A. Glycobiology 3 (1993) 97
10. Lin P., Lee C.L., and Sim M.M. J. Org. Chem. 66 (2001) 8243
11. Sharma G.V.M., Jyothi Y., and Sree Lakshmi P. Synth. Commun. 36 (2006) 2991
12. Nagarapu L., Satyender A., and Srinivas K. J. Mol. Catal. A: Chem. 266 (2006) 104
13. Srinivas K., Srinivasu V.N.V., Dhanraj B.O., and Nagarapu L. J. Mol. Catal. A: Chem. 266 (2006) 109
14. 3 (2 × 200 mL). The combined extracts were concentrated to give 6 (1.08 g, 71.52 %) as a colourless powder, m.p. 210-212 °C
15. 2O (50%) at a concentration of 150 μg/mL. The concentrations were further made by twofold dilution with culture medium and bacterial solution at the first tube.
16. E. Margery Linday, Practical Introduction to Microbiology, E & F.N. Spon, UK (1962) 177.
17. NCCLS, Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria, Which Grows Aerobically (fifth ed.), NCCLS, Villanova, PA (2000) Approved Standard M 7-A5.