Inhibitory effects of retinoic acid and IIF on growth, migration and invasiveness in the U87MG human glioblastoma cell line

Oncology Reports

Volumn 18, Issue 4, 2007, Pages 1015-1021

  Papi, A ^a   Bartolini, G ^a   Ammar, K ^a   Guerra, F ^a   Ferreri, Anna Maria ^a   Rocchi, P ^a   Orlandi, M ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Glioblastoma; IIF; Invasion; Metalloproteinases; Retinoids

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; GELATINASE A; GELATINASE B; IIF COMPOUND; LIPOCORTIN 5; MESSENGER RNA; RETINOIC ACID; RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; BRAIN TUMOR; CANCER INVASION; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; DRUG EFFECT; GENETICS; GLIOBLASTOMA; HUMAN; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; GLIOBLASTOMA; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 38449121992     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.4.1015     Document Type: Article

References (46)

1. Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC and Cavenee WK: The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61: 215-225, 2002. (Pubitemid 34212595)
2. Sanson M, Thillet J and Hoang-Xuan K: Molecular changes in gliomas. Curr Opin Oncol 16: 607-613, 2004. (Pubitemid 39482982)
3. Desjardins A, Rich JN, Quinn JA, Vredenburgh J, Gururang S, Sathornsumetee S, Reardon DA, Friedman AH, Bigner DD and Friedman HS: Chemotherapy and novel therapeutic approaches in malignant glioma. Front Biosci 10: 2645-2668, 2005. (Pubitemid 40905267)
4. Prados MD and Levin V: Biology and treatment of malignant glioma. Semin Oncol 27: 1-10, 2000. (Pubitemid 30390229)
5. Giese A, Bjerkvig R, Berens ME and Westphal M: Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 21: 1624-1636, 2003. (Pubitemid 46594118)
6. Rasheed BK, Wiltshire RN, Bigner SH and Bigner DD: Molecular pathogenesis of malignant gliomas. Curr Opin Oncol 11: 162-167, 1999. (Pubitemid 29229607)
7. Rooprai HK and McCormick D: Proteases and their inhibitors in human brain tumors: a review. Anticancer Res 17: 4151-4162, 1997. (Pubitemid 28017946)
8. Vince GH, Wagner S, Pietsch T, Klein R, Goldbrunner RH, Roseen K and Tonn JC: Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas. Int J Dev Neurosci 17: 437-445, 1999. (Pubitemid 29421831)
9. Forsyth PA, Wong H, Laing TD, Rewcastle NB, Morris DG, Muzik H, Leco KJ, Johnston RN, Brasher PM, Sutherland G and Edwards DR: Gelatinase-A MMP2, gelatinase-B MMP-9 and membrane type matrix metalloproteinase-1 MT1-MMP are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer 79: 1828-1835, 1999. (Pubitemid 29132312)
10. Stetler-Stevenson WG and Yu AE: Proteases in invasion: matrix metalloproteinases. Cancer Biol 11: 143-152, 2001. (Pubitemid 32423289)
11. Wang M, Wang GT, Liu S, Yoshida D and Teramoto A: The expression of matrix metalloproteinase-2 and -9 in human gliomas of different pathological grades. Brain Tumor Pathol 20: 65-72, 2003. (Pubitemid 38146273)
12. Groft LL, Muzik H, Rewcastle NB, Johnston RN, Knauper V, Lafleur MA, Forsyth PA and Edwards DR: Differential expression and localization of TIMP-1 and TIMP-2 in human gliomas. Br J Cancer 85: 55-63, 2001. (Pubitemid 32695716)
13. Nakada M, Kita D, Futami K, Yamashita J, Fujimoto N, Sato H and Okada Y: Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma. J Neurosurg 94: 464-473, 2001. (Pubitemid 32786027)
14. Correa TC, Brohem CA and Winnischofer SM: Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness. J Cell Biochem 99: 156-167, 2006.
15. Kagechica H and Shudo K: Synthetic retinoids: recent development concerning structure and clinical utility. J Med Chem 48: 5875-5883, 2005.
16. Sun SY and Lotan R: Retinoids and their receptors in cancer development and chemoprevention. Crit Rev Oncol Hematol 41: 41-55, 2002.
17. Jimenez-Lara AM, Clarke N, Altucci L and Gronemeyer H: Retinoic acid induced apoptosis in leukemia cells. Mol Med 10: 508-515, 2004. (Pubitemid 39303624)
18. Altucci L, Rosin A, Hirsch O, et al: Rexinoid-triggered differentiation and tumor selective apoptosis of acute myeloid leukemia by protein kinase A mediated desubordination of retinoid X receptor. Cancer Res 65: 8754-8765, 2005. (Pubitemid 41377364)
19. Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ and Dmitrovsky E: A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. J Natl Cancer Inst 97: 1645-1651, 2005. (Pubitemid 41672230)
20. Villabianca JG, Krailo MD, Ames MM, Reid JM, Reaman GH and Reynolds PC: Phase I trial of oral fenretinide in children with high-risk solid tumors: a report from the Children's Oncology Group (CCG 09709). J Clin Oncol 24: 3423-3430, 2006. (Pubitemid 46638899)
21. Kong G, Kim HT, Wu K, DeNardo D, Hilsenbeck SG, Xu XC, Lamph WW, Bissonnette R, Dannenberg AJ and Brown PH: The retinoid X receptor-selective retinoid, LGD1069, downregulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer Res 65: 3462-3469, 2005. (Pubitemid 40524633)
22. Orlandi M, Mantovani B, Ammar K, Dal Monte P and Bartolini G: Retinoids and cancer: antitumoral effects of ATRA, 9-cisRA and the new retinoid IIF on the HL-60 leukemic cell line. Med Princ Pract 12: 164-169, 2003. (Pubitemid 36667647)
23. Bartolini G, Orlandi M, Ammar K, Magrini E, Ferreri AM and Rocchi P: Effect of a new derivative of retinoic acid on proliferation and differentiation in human neuroblastoma cells. Anticancer Res 23: 1495-1500, 2003.
24. Bartolini G, Ammar K, Mantovani B, Scannabissi F, Ferreri AM, Rocchi P and Orlandi M: Retinoid and cancer: antitumor effect of ATRA and of a new derivative of retinoic acid, IIF, on colon carcinoma cell lines CaCo-2 and HT-29. Anticancer Res 24: 1779-1783, 2004. (Pubitemid 38954709)
25. Bartolini G, Orlandi M, Papi A, Ammar A, Guerra A, Ferreri AM and Rocchi P: Search for multidrug resistance modulators: effects of retinoids in human colon carcinoma cells. In Vivo 20: 729-733, 2006.
26. Pawels R, Balzarini J, Baba M, Snoeck R and Schols D: Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J Virol Methods 20: 390-391, 1988.
27. Casciola-Rosen L, Rosen A, Petri M and Schlissel M: Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. Proc Natl Acad Sci USA 93: 1624-1629, 1996. (Pubitemid 26075176)
28. Leber TM and Balkwill FR: Zimography: a single-step staining method for quantitation of proteolytic activity on substrate gels. Anal Biochem 249: 24-28, 1997. (Pubitemid 27251938)
29. Lowry DH, Rosebrough NJ, Farr AL and Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
30. Terranova VP, Hic S, Diflorio RM and Lyall RM: Tumor cell metastasis. Crit Rev Oncol Hematol 5: 87-114, 1986. (Pubitemid 16120470)
31. Koopman G, Reutelingsperger CP, Kujten GA, et al: Annexin V for flow cytometric of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84: 1415-1420, 1994. (Pubitemid 24273007)
32. Susin SA, Zanzami M, Castedo T, et al: Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 184: 1331-1341, 1994. (Pubitemid 26354689)
33. Adams JM and Cory S: The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326, 1998. (Pubitemid 28406819)
34. Reed JC: Bcl-2 family proteins: regulators of apoptosis and chemoresistance in hematologic malignancies. Semin Hematol 34: 9-19, 1997.
35. Wild-Bode C: Molecular determinants of glioma cell migration and invasion. FASEB J 13: 781-792, 2001.
36. Wu XZ, Zhang L, Shi BZ and Hu P: Inhibitory effects of N-(4-hydrophenyl)retinamide on liver cancer and malignant melanoma cells. World J Gastroenterol 11: 5763-5769, 2005. (Pubitemid 41662823)
37. Golubkov V, Garcia A and Markland FS: Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells. Anticancer Res 25: 249-253, 2005. (Pubitemid 40470117)
38. Yamamoto M, Ueno Y, Hayashi S and Fukushima T: The role of proteolysis on tumor invasiveness in glioblastoma and metastatic brain tumors. Anticancer Res 22: 4265-4268, 2002. (Pubitemid 36134470)
39. Komatsu K, Nakanishi Y, Nemoto N, Hori T, Sawada T and Kobayashi M: Expression and quantitative analysis of matrix metalloproteinase-2 and -9 in human gliomas. Brain Tumor Pathol 21: 105-112, 2004. (Pubitemid 40187984)
40. Murphy G, Knauper V, Lee MH, Amour A, Worley JR, Hutton M, Atkinson S, Rapti M and Williamson R: Role of TIMPs (tissue inhibitors of metalloproteinases) in pericellular proteolysis: the specificity in the detail. Biochem Soc Symp 70: 65-80, 2003. (Pubitemid 38497216)
41. Rao J, Yamamoto M, Mohamans S, et al: Expression and localization of 92 kDa type IV collagenase/MMP9 in human gliomas. Clin Exp Metastasis 14: 8-12, 1996.
42. Bode W and Maskos K: Structural basis of the matrix metalloproteinases and their physiological inhibitors, the tissue inhibitors of metalloproteinases. Biol Chem 384: 863-872, 2003. (Pubitemid 36874500)
43. Nagase H, Visse R and Murphy G: Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 69: 562-573, 2006. (Pubitemid 43139720)
44. Flannery CR: MMPs and ADAMTs: functional studies. Front Biosci 11: 544-569, 2006.
45. Fisher JF and Mobashery S: Recent advances in MMP inhibitor design. Cancer Metastasis Rev 25: 115-136, 2006. (Pubitemid 43723987)
46. Germanov E, Berman JN and Guernsey DL: Current and future approaches for the therapeutic targeting of metastasis (Review). Int J Mol Med 18: 1025-1036, 2006.