Discovery of a Small Molecule PDI Inhibitor That Inhibits Reduction of HIV-1 Envelope Glycoprotein gp120

ACS Chemical Biology

Volumn 6, Issue 3, 2011, Pages 245-251

  Khan, Maola M G ^a,b   Simizu, Siro ^a,c   Lai, Ngit Shin ^a,d   Kawatani, Makoto ^a   Shimizu, Takeshi ^a   Osada, Hiroyuki ^a,b  

^a RIKEN   (Japan)

^b SAITAMA UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d INSTITUTE FOR RESEARCH IN MOLECULAR MEDICINE INFORMM   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLYCOPROTEIN GP 120; JUNIFERDIN; OXIDOREDUCTASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHODIESTERASE REDUCTASE; PROTEIN ERP57; PROTEIN ERP72; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; PARTICLE SIZE; PRIORITY JOURNAL; PURIFICATION; SCREENING TEST; STRUCTURE ACTIVITY RELATION; VIRUS ENVELOPE;

DIETHYLSTILBESTROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME INHIBITORS; ESTRONE; HIGH-THROUGHPUT SCREENING ASSAYS; HIV ENVELOPE PROTEIN GP120; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NORDIHYDROGUAIARETIC ACID; OXIDATION-REDUCTION; PARABENS; PROTEIN DISULFIDE-ISOMERASES; PROTEIN FOLDING; SESQUITERPENES; SMALL MOLECULE LIBRARIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79955574624     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb100387r     Document Type: Article

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