A high-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activity

Journal of Biomolecular Screening

Volumn 9, Issue 7, 2004, Pages 614-620

  Smith, Anthony M ^a   Chan, John ^a   Oksenberg, Donna ^a   Urfer, Roman ^a   Wexler, David S ^a   Ow, Arnie ^a   Gao, Liping ^a   McAlorum, Alanna ^a   Huang, Shu Gui ^a  

^a AGY Therapeutics Inc   (United States)

Author keywords

High throughput screening; Protein disulfide isomerase; Reductive cleavage of disulfide bonds; Turbidometric assay

Indexed keywords

DITHIOTHREITOL; HYDROGEN PEROXIDE; INSULIN; ISOMERASE INHIBITOR; PROTEIN DISULFIDE ISOMERASE; SECRETORY PROTEIN;

ARTICLE; CATALYSIS; COST EFFECTIVENESS ANALYSIS; DISULFIDE BOND; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME KINETICS; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; PROTEIN FOLDING; REDUCTION; SPECTROPHOTOMETRY; TURBIDIMETRY; VALIDATION PROCESS;

ANIMALS; BACITRACIN; BIOLOGICAL ASSAY; CATALYSIS; CATTLE; DIMETHYL SULFOXIDE; ENZYME INHIBITORS; HYDROGEN PEROXIDE; INSULIN; LEAST-SQUARES ANALYSIS; PROTEIN DISULFIDE-ISOMERASE; TIME FACTORS;

EUKARYOTA;

EID: 17044417590     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057104265292     Document Type: Article

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