Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N′-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3- carbohydrazide 1,1-dioxides as anti-microbial agents

European Journal of Medicinal Chemistry

Volumn 46, Issue 6, 2011, Pages 2368-2377

  Ahmad, Naveed ^a   Zia Ur Rehman, Muhammad ^b   Siddiqui, Hamid Latif ^a   Ullah, Muhammad Fasih ^a   Parvez, Masood ^c  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b APPLIED CHEMISTRY RESEARCH CENTRE   (Pakistan)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

1,2 Benzothiazine 1,1 dioxide; 1,4 Dihydropyrazolo 4,3 c 1,2 benzothiazin 3 ol 5,5 dioxide; Benzothiazine carbohydrazides; Microwaves assisted synthesis; Sodium saccharin

Indexed keywords

1,4 DIHYDROPYRAZOLO[4,3 C][1,2]BENZOTHIAZIN 3 OL 5,5 DIOXIDE; 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (2 HYDROXYPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (3 HYDROXYPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (3 METHOXYPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (4 HYDROXYPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (4 IODOPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; 4 HYDROXY N' [1 (4 METHOXYPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BIFONAZOLE; METHYL (1,1 DIOXIDO 3 OXO 1,2 BENZISOTHIAZOL 2(3H) YL) ACETATE; METHYL 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOXYLATE 1,1 DIOXIDE; METHYL 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOXYLATE 1,1 DIOXIDE; N' [1 (2 BROMOPHENYL)ETHYLIDENE] 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2 BROMOPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2 CHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2 CHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2,4 DICHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2,4 DICHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (2,4 DIFLUOROPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (3,4 DICHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (3,4 DICHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (4 AMINOPHENYL)ETHYLIDENE] 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (4 BROMOPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (4 CHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2 METHYL 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; N' [1 (4 CHLOROPHENYL)ETHYLIDENE] 4 HYDROXY 2H 1,2 BENZOTHIAZINE 3 CARBOHYDRAZIDE 1,1 DIOXIDE; STREPTOMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGI; HYDRAZINES; MICROBIAL SENSITIVITY TESTS; MICROWAVES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZINES;

EID: 79955573819     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.03.020     Document Type: Article

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