Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 5, 2011, Pages 1129-1136

  Suzuki, Maiko ^a   Endo, Manabu ^a   Shinohara, Fumiaki ^a   Echigo, Seishi ^a   Rikiishi, Hidemi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Akt mTOR; Apoptosis; Rapamycin; ROS; Selenite; Seleno L methionine

Indexed keywords

2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 2 MORPHOLINO 8 PHENYLCHROMONE; 3 METHYLADENINE; ACETYLCYSTEINE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SELENIUM DERIVATIVE; SELENOMETHIONINE; SODIUM SELENITE; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN A549; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; DRUG EFFICACY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG ADENOCARCINOMA; NICK END LABELING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LUNG NEOPLASMS; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SELENOMETHIONINE; SIGNAL TRANSDUCTION; SIROLIMUS; SODIUM SELENITE; TOR SERINE-THREONINE KINASES;

EID: 79955568265     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1417-7     Document Type: Article

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