Shortened β-cell lifespan leads to β-cell deficit in a rodent model of type 2 diabetes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 300, Issue 5, 2011, Pages

  Manesso, Erica ^a,b   Toffolo, Gianna M ^a   Butler, Alexandra E ^b   Butler, Peter C ^b   Cobelli, Claudio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cell age; Diabetes; Mathematical model

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL AGING; CELL HETEROGENEITY; CELL REGENERATION; CONTROLLED STUDY; LIFESPAN; MATHEMATICAL MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

AGING; ALGORITHMS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; CELL COUNT; CELL DEATH; DIABETES MELLITUS, TYPE 2; HUMANS; IN SITU NICK-END LABELING; INSULIN-SECRETING CELLS; LONGEVITY; MODELS, STATISTICAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79955567066     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00504.2010     Document Type: Article

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