Regioselective one pot synthesis of 3,3′-diindolylethylene derivatives and study of their cytotoxic activity

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 10, 2011, Pages 3084-3087

  Mandal, Madhumita ^a   Kumar, Deepak ^a   Roy, Rajneeta ^a   Sen, Rupashree ^b   Das, Padma ^a   Chatterjee, Mitali ^b   Jaisankar, Parasuraman ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Diindolyl ethylene; Friedel Crafts acylation; In vitro cytotoxic activity; MTS PMS assay; Nitroethane

Indexed keywords

2 (1H INDOLYL 2 YL)PHENOL; 2 PHENYL INDOLE; 2,2' DIPHENYL 3,3' DIINDOLYLETHYLENE DERIVATIVE; 3 ACETYL 2 PHENYLINDOLE; CYTOTOXIC AGENT; INDOLE DERIVATIVE; LEWIS ACID; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CYTOTOXICITY; DRUG STRUCTURE; FRIEDEL CRAFTS REACTION; HUMAN; HUMAN CELL; IC 50; ONE POT SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; ETHYLENES; FLOW CYTOMETRY; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE;

EID: 79955564732     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.03.028     Document Type: Article

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