Chemical toxicity testing in vitro using cytochrome P450-expressing cell lines, such as human CYP1B1

Nature Protocols

Volumn 6, Issue 5, 2011, Pages 677-688

  Landsiedel, Robert ^a,b   Fabian, Eric ^b   Tralau, Tewes ^c,e   Luch, Andreas ^d,e  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b BASF SE   (Germany)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 1B1; DIBENZO[A,L]PYRENE; ETHOXYRESORUFIN DEETHYLASE; MESSENGER RNA; POLYCYCLIC AROMATIC HYDROCARBON;

ANIMAL CELL CULTURE; ARTICLE; CELL SELECTION; CHINESE HAMSTER; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; FIBROBLAST; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOFLUORESCENCE; IN VITRO STUDY; METABOLIC ACTIVATION; MICRONUCLEUS; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; SPECIES DIFFERENCE; TOXICITY TESTING;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CHO CELLS; CRICETINAE; CRICETULUS; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; TOXICITY TESTS;

CRICETULUS GRISEUS;

EID: 79955525884     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2011.316     Document Type: Article

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