Use of V79 cells with stably transfected cytochrome P450 cDNAs in studying the metabolism and effects of cytotoxic drugs

Cancer Chemotherapy and Pharmacology

Volumn 43, Issue 1, 1999, Pages 59-67

  Philip, Philip Agop ^a   Ali Sadat, Shadan ^a   Doehmer, Johannes ^b   Kocarek, Thomas ^a   Akhtar, Aftab ^a   Lu, Hong ^c   Chan, Kenneth K ^c  

^a WAYNE STATE UNIVERSITY   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Cyclophosphamide; Cytochrome P450; Drug metabolism; Ifosfamide; Paclitaxel; V79 cells

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOCHROME P450; CYTOTOXIC AGENT; IFOSFAMIDE; METYRAPONE; MIDAZOLAM; PACLITAXEL; TROLEANDOMYCIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHINESE HAMSTER; CYTOTOXICITY; DRUG METABOLISM; FIBROBLAST; GAS CHROMATOGRAPHY; GENETIC TRANSFECTION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE; COCULTURE TECHNIQUES; CRICETINAE; CRICETULUS; CYCLOPHOSPHAMIDE; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; HUMANS; IFOSFAMIDE; MIXED FUNCTION OXYGENASES; PACLITAXEL;

EID: 0032958147     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050863     Document Type: Article

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