Tumoricidal bystander effect in the suicide gene therapy using mesenchymal stem cells does not injure normal brain tissues

Cancer Letters

Volumn 306, Issue 1, 2011, Pages 99-105

  Amano, Shinji ^a   Gu, Chunyu ^a,b   Koizumi, Shinichiro ^a   Tokuyama, Tsutomu ^a   Namba, Hiroki ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Bystander effect; Glioma; Herpes simplex virus thymidine kinase; Mesenchymal stem cell; Suicide gene therapy

Indexed keywords

GANCICLOVIR;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN TISSUE; BYSTANDER EFFECT; CANCER GENE THERAPY; CANCER SURVIVAL; CELL COUNT; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; GENETIC TRANSDUCTION; GLIOMA; GLIOMA CELL; HERPES SIMPLEX VIRUS THYMIDINE KINASE GENE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; INJECTION SITE REACTION; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SUICIDE GENE THERAPY; SURVIVAL TIME; VIRUS GENE;

ANIMALS; APOPTOSIS; BRAIN; BRAIN NEOPLASMS; BYSTANDER EFFECT; CELL LINE, TUMOR; COCULTURE TECHNIQUES; GENE THERAPY; MESENCHYMAL STEM CELLS; NEUROGLIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SIMPLEXVIRUS; THYMIDINE KINASE; TIME FACTORS;

RATTUS; SIMPLEXVIRUS;

EID: 79955484397     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.02.037     Document Type: Article

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