Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: Comparison with atypical antipsychotics

Neurochemistry International

Volumn 38, Issue 5, 2001, Pages 425-435

  Balijepalli, Sadguna ^a   Kenchappa, Rajappa S ^a   Boyd, Michael R ^b   Ravindranath, Vijayalakshmi ^a,c  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

Antipsychotic; Brain; Complex I; Haloperidol; Mitochondria; Oxidative stress

Indexed keywords

ANTIOXIDANT; CLOZAPINE; DITHIOTHREITOL; GLUTATHIONE ISOPROPYL ESTER; HALOPERIDOL; NEUROLEPTIC AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RISPERIDONE; THIOCTIC ACID; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME INHIBITION; EXTRAPYRAMIDAL SYMPTOM; EXTRAPYRAMIDAL SYSTEM; FRONTAL CORTEX; HIPPOCAMPUS; MALE; MESENCEPHALON; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY CHAIN;

ANIMALS; ANTIPSYCHOTIC AGENTS; BRAIN; ELECTRON TRANSPORT COMPLEX I; HALOPERIDOL; MALE; MICE; MITOCHONDRIA; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; SULFHYDRYL COMPOUNDS;

EID: 0035108147     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(00)00108-X     Document Type: Article

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