-
1
-
-
2442629479
-
Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization
-
Alfthan K., Heiska L., Gronholm M., Renkema G.H., Carpen O. Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization. J Biol Chem 2004, 279(18):18559-18566.
-
(2004)
J Biol Chem
, vol.279
, Issue.18
, pp. 18559-18566
-
-
Alfthan, K.1
Heiska, L.2
Gronholm, M.3
Renkema, G.H.4
Carpen, O.5
-
2
-
-
34250693117
-
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development
-
Others
-
Benninger Y., Thurnherr T., Pereira J.A., Krause S., Wu X., Chrostek-Grashoff A., Herzog D., Nave K.A., Franklin R.J., Meijer D., others Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol 2007, 177(6):1051-1061.
-
(2007)
J Cell Biol
, vol.177
, Issue.6
, pp. 1051-1061
-
-
Benninger, Y.1
Thurnherr, T.2
Pereira, J.A.3
Krause, S.4
Wu, X.5
Chrostek-Grashoff, A.6
Herzog, D.7
Nave, K.A.8
Franklin, R.J.9
Meijer, D.10
-
3
-
-
33745229355
-
Role of integrins in peripheral nerves and hereditary neuropathies
-
Berti C., Nodari A., Wrabetz L., Feltri M.L. Role of integrins in peripheral nerves and hereditary neuropathies. Neuromolecular Med 2006, 8(1-2):191-204.
-
(2006)
Neuromolecular Med
, vol.8
, Issue.1-2
, pp. 191-204
-
-
Berti, C.1
Nodari, A.2
Wrabetz, L.3
Feltri, M.L.4
-
4
-
-
34247863773
-
The neuregulin-I/ErbB signaling system in development and disease
-
Britsch S. The neuregulin-I/ErbB signaling system in development and disease. Adv Anat Embryol Cell Biol 2007, 190:1-65.
-
(2007)
Adv Anat Embryol Cell Biol
, vol.190
, pp. 1-65
-
-
Britsch, S.1
-
5
-
-
0018381233
-
Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve
-
Brockes J.P., Fields K.L., Raff M.C. Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res 1979, 165(1):105-118.
-
(1979)
Brain Res
, vol.165
, Issue.1
, pp. 105-118
-
-
Brockes, J.P.1
Fields, K.L.2
Raff, M.C.3
-
6
-
-
0034658555
-
Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells
-
Chen L.M., Bailey D., Fernandez-Valle C. Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells. J Neurosci 2000, 20(10):3776-3784.
-
(2000)
J Neurosci
, vol.20
, Issue.10
, pp. 3776-3784
-
-
Chen, L.M.1
Bailey, D.2
Fernandez-Valle, C.3
-
7
-
-
34247562835
-
Rac, membrane heterogeneity, caveolin and regulation of growth by integrins
-
Del Pozo M.A., Schwartz M.A. Rac, membrane heterogeneity, caveolin and regulation of growth by integrins. Trends Cell Biol 2007, 17(5):246-250.
-
(2007)
Trends Cell Biol
, vol.17
, Issue.5
, pp. 246-250
-
-
Del Pozo, M.A.1
Schwartz, M.A.2
-
8
-
-
54849407866
-
-
J Neurosci 2008 Oct 15, 28(42):10472-10481.
-
(2008)
J Neurosci
, vol.28
, Issue.42
, pp. 10472-10481
-
-
-
9
-
-
54849407866
-
Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves
-
Denisenko N., Cifuentes-Diaz C., Irinopoulou T., Carnaud M., Benoit E., Niwa-Kawakita M., Chareyre F., Giovannini M., Girault J.A., Goutebroze L. Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves. J Neurosci 2008, 28(42):10472-10481.
-
(2008)
J Neurosci
, vol.28
, Issue.42
, pp. 10472-10481
-
-
Denisenko, N.1
Cifuentes-Diaz, C.2
Irinopoulou, T.3
Carnaud, M.4
Benoit, E.5
Niwa-Kawakita, M.6
Chareyre, F.7
Giovannini, M.8
Girault, J.A.9
Goutebroze, L.10
-
10
-
-
0031453392
-
Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination
-
Einheber S., Zanazzi G., Ching W. Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination. J Cell Biol 1997, 139(6):1495-1506.
-
(1997)
J Cell Biol
, vol.139
, Issue.6
, pp. 1495-1506
-
-
Einheber, S.1
Zanazzi, G.2
Ching, W.3
-
11
-
-
61549106017
-
The function of RhoGTPases in axon ensheathment and myelination
-
Feltri M.L., Suter U., Relvas J.B. The function of RhoGTPases in axon ensheathment and myelination. Glia 2008, 56:1508-1517.
-
(2008)
Glia
, vol.56
, pp. 1508-1517
-
-
Feltri, M.L.1
Suter, U.2
Relvas, J.B.3
-
12
-
-
0036699082
-
Paxillin binds schwannomin and regulates its density dependent localization and effect on cell morphology
-
Fernandez-Valle C., Tang Y., Ricard J., Rodenas-Ruano A., Taylor A., Hackler E., Biggerstaff J., Iacovelli J. Paxillin binds schwannomin and regulates its density dependent localization and effect on cell morphology. Nat Genet 2002, 31(4):354-362.
-
(2002)
Nat Genet
, vol.31
, Issue.4
, pp. 354-362
-
-
Fernandez-Valle, C.1
Tang, Y.2
Ricard, J.3
Rodenas-Ruano, A.4
Taylor, A.5
Hackler, E.6
Biggerstaff, J.7
Iacovelli, J.8
-
13
-
-
0042733242
-
Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of Ranvier
-
Gatto C.L., Walker B.J., Lambert S. Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of Ranvier. J Cell Biol 2003, 162(3):489-498.
-
(2003)
J Cell Biol
, vol.162
, Issue.3
, pp. 489-498
-
-
Gatto, C.L.1
Walker, B.J.2
Lambert, S.3
-
14
-
-
33845386985
-
Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility
-
Gatto C.L., Walker B.J., Lambert S. Asymmetric ERM activation at the Schwann cell process tip is required in axon-associated motility. J Cell Physiol 2007, 210(1):122-132.
-
(2007)
J Cell Physiol
, vol.210
, Issue.1
, pp. 122-132
-
-
Gatto, C.L.1
Walker, B.J.2
Lambert, S.3
-
15
-
-
0034234894
-
Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2
-
Giovannini M., Robanus-Maandag E., van der Valk M., Niwa-Kawakita M., Abramowski V., Goutebroze L., Woodruff J.M., Berns A., Thomas G. Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Genes Dev 2000, 14(13):1617-1630.
-
(2000)
Genes Dev
, vol.14
, Issue.13
, pp. 1617-1630
-
-
Giovannini, M.1
Robanus-Maandag, E.2
van der Valk, M.3
Niwa-Kawakita, M.4
Abramowski, V.5
Goutebroze, L.6
Woodruff, J.M.7
Berns, A.8
Thomas, G.9
-
16
-
-
3442880458
-
A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor
-
Hirokawa Y., Tikoo A., Huynh J., Utermark T., Hanemann C.O., Giovannini M., Xiao G.H., Testa J.R., Wood J., Maruta H. A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor. Cancer J 2004, 10(1):20-26.
-
(2004)
Cancer J
, vol.10
, Issue.1
, pp. 20-26
-
-
Hirokawa, Y.1
Tikoo, A.2
Huynh, J.3
Utermark, T.4
Hanemann, C.O.5
Giovannini, M.6
Xiao, G.H.7
Testa, J.R.8
Wood, J.9
Maruta, H.10
-
17
-
-
0032168919
-
A dicistronic retroviral vector and culture model for analysis of neuron-Schwann cell interactions
-
Howe D.G., McCarthy K.D. A dicistronic retroviral vector and culture model for analysis of neuron-Schwann cell interactions. J Neurosci Methods 1998, 83(2):133-142.
-
(1998)
J Neurosci Methods
, vol.83
, Issue.2
, pp. 133-142
-
-
Howe, D.G.1
McCarthy, K.D.2
-
18
-
-
0037026595
-
Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene
-
Johnson K.C., Kissil J.L., Fry J.L., Jacks T. Cellular transformation by a FERM domain mutant of the Nf2 tumor suppressor gene. Oncogene 2002, 1(39):5990-5997.
-
(2002)
Oncogene
, vol.1
, Issue.39
, pp. 5990-5997
-
-
Johnson, K.C.1
Kissil, J.L.2
Fry, J.L.3
Jacks, T.4
-
19
-
-
0038344831
-
Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells
-
Kaempchen K., Mielke K., Utermark T., Langmesser S., Hanemann C.O. Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells. Hum Mol Genet 2003, 12(11):1211-1221.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.11
, pp. 1211-1221
-
-
Kaempchen, K.1
Mielke, K.2
Utermark, T.3
Langmesser, S.4
Hanemann, C.O.5
-
20
-
-
0037155916
-
Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization
-
Kissil J.L., Johnson K.C., Eckman M.S., Jacks T. Merlin phosphorylation by p21-activated kinase 2 and effects of phosphorylation on merlin localization. J Biol Chem 2002, 277(12):10394-10399.
-
(2002)
J Biol Chem
, vol.277
, Issue.12
, pp. 10394-10399
-
-
Kissil, J.L.1
Johnson, K.C.2
Eckman, M.S.3
Jacks, T.4
-
21
-
-
0242298576
-
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1
-
Kissil J.L., Wilker E.W., Johnson K.C., Eckman M.S., Yaffe M.B., Jacks T. Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1. Mol Cell 2003, 12(4):841-849.
-
(2003)
Mol Cell
, vol.12
, Issue.4
, pp. 841-849
-
-
Kissil, J.L.1
Wilker, E.W.2
Johnson, K.C.3
Eckman, M.S.4
Yaffe, M.B.5
Jacks, T.6
-
22
-
-
0032578033
-
Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization
-
LaJeunesse D.R., McCartney B.M., Fehon R.G. Structural analysis of Drosophila merlin reveals functional domains important for growth control and subcellular localization. J Cell Biol 1998, 141(7):1589-1599.
-
(1998)
J Cell Biol
, vol.141
, Issue.7
, pp. 1589-1599
-
-
LaJeunesse, D.R.1
McCartney, B.M.2
Fehon, R.G.3
-
23
-
-
60149106862
-
Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas
-
Lallemand D., Manent J., Couvelard A., Watilliaux A., Siena M., Chareyre F., Lampin A., Niwa-Kawakita M., Kalamarides M., Giovannini M. Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas. Oncogene 2009, 28(6):854-865.
-
(2009)
Oncogene
, vol.28
, Issue.6
, pp. 854-865
-
-
Lallemand, D.1
Manent, J.2
Couvelard, A.3
Watilliaux, A.4
Siena, M.5
Chareyre, F.6
Lampin, A.7
Niwa-Kawakita, M.8
Kalamarides, M.9
Giovannini, M.10
-
24
-
-
33846702026
-
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac
-
Morrison H., Sperka T., Manent J., Giovannini M., Ponta H., Herrlich P. Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. Cancer Res 2007, 67(2):520-527.
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 520-527
-
-
Morrison, H.1
Sperka, T.2
Manent, J.3
Giovannini, M.4
Ponta, H.5
Herrlich, P.6
-
25
-
-
33645457467
-
Temporal control of Rac in Schwann cell-axon interaction is disrupted in NF2-mutant schwannoma cells
-
Nakai Y., Zheng Y., MacCollin M., Ratner N. Temporal control of Rac in Schwann cell-axon interaction is disrupted in NF2-mutant schwannoma cells. J Neurosci 2006, 26(13):3390-3395.
-
(2006)
J Neurosci
, vol.26
, Issue.13
, pp. 3390-3395
-
-
Nakai, Y.1
Zheng, Y.2
MacCollin, M.3
Ratner, N.4
-
26
-
-
34250740938
-
Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination
-
Nodari A., Zambroni D., Quattrini A., Court F.A., D'Urso A., Recchia A., Tybulewicz V.L., Wrabetz L., Feltri M.L. Beta1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination. J Cell Biol 2007, 177(6):1063-1075.
-
(2007)
J Cell Biol
, vol.177
, Issue.6
, pp. 1063-1075
-
-
Nodari, A.1
Zambroni, D.2
Quattrini, A.3
Court, F.A.4
D'Urso, A.5
Recchia, A.6
Tybulewicz, V.L.7
Wrabetz, L.8
Feltri, M.L.9
-
27
-
-
0031738241
-
Merlin, the neurofibromatosis type 2 gene product, and beta1 integrin associate in isolated and differentiating Schwann cells
-
Obremski V.J., Hall A.M., Fernandez-Valle C. Merlin, the neurofibromatosis type 2 gene product, and beta1 integrin associate in isolated and differentiating Schwann cells. J Neurobiol 1998, 37(4):487-501.
-
(1998)
J Neurobiol
, vol.37
, Issue.4
, pp. 487-501
-
-
Obremski, V.J.1
Hall, A.M.2
Fernandez-Valle, C.3
-
28
-
-
27544514090
-
Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
-
Okada T., Lopez-Lago M., Giancotti F.G. Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane. J Cell Biol 2005, 171(2):361-371.
-
(2005)
J Cell Biol
, vol.171
, Issue.2
, pp. 361-371
-
-
Okada, T.1
Lopez-Lago, M.2
Giancotti, F.G.3
-
29
-
-
34247609343
-
Shedding light on Merlin's wizardry
-
Okada T., You L., Giancotti F.G. Shedding light on Merlin's wizardry. Trend Cell Biol 2007, 17(5):222-229.
-
(2007)
Trend Cell Biol
, vol.17
, Issue.5
, pp. 222-229
-
-
Okada, T.1
You, L.2
Giancotti, F.G.3
-
30
-
-
24144458264
-
A Rac switch regulates random versus directionally persistent cell migration
-
Pankov R., Endo Y., Even-Ram S., Araki M., Clark K., Cukierman E., Matsumoto K., Yamada K.M. A Rac switch regulates random versus directionally persistent cell migration. J Cell Biol 2005, 170(5):793-802.
-
(2005)
J Cell Biol
, vol.170
, Issue.5
, pp. 793-802
-
-
Pankov, R.1
Endo, Y.2
Even-Ram, S.3
Araki, M.4
Clark, K.5
Cukierman, E.6
Matsumoto, K.7
Yamada, K.M.8
-
31
-
-
0034660093
-
Fluorescent myelin proteins provide new tools to study the myelination process
-
Pedraza L., Colman D.R. Fluorescent myelin proteins provide new tools to study the myelination process. J Neurosci Res 2000, 60(6):697-703.
-
(2000)
J Neurosci Res
, vol.60
, Issue.6
, pp. 697-703
-
-
Pedraza, L.1
Colman, D.R.2
-
32
-
-
0032578798
-
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells
-
Pelton P.D., Sherman L.S., Rizvi T.A., Marchionni M.A., Wood P., Friedman R.A., Ratner N. Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells. Oncogene 1998, 17(17):2195-2209.
-
(1998)
Oncogene
, vol.17
, Issue.17
, pp. 2195-2209
-
-
Pelton, P.D.1
Sherman, L.S.2
Rizvi, T.A.3
Marchionni, M.A.4
Wood, P.5
Friedman, R.A.6
Ratner, N.7
-
33
-
-
27744472306
-
A new method of selecting Schwann cells from adult mouse sciatic nerve
-
Pannunzio M.E., Jou I.M., Long A., Wind T.C., Beck G., Balian G. A new method of selecting Schwann cells from adult mouse sciatic nerve. J Neurosci Methods 2005, 149(1):74-81.
-
(2005)
J Neurosci Methods
, vol.149
, Issue.1
, pp. 74-81
-
-
Pannunzio, M.E.1
Jou, I.M.2
Long, A.3
Wind, T.C.4
Beck, G.5
Balian, G.6
-
34
-
-
0027245423
-
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
-
others
-
Rouleau G.A., Merel P., Lutchman M., Sanson M., Zucman J., Marineau C., Hoang-Xuan K., Demczuk S., Desmaze C., Plougastel B., others Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature 1993, 363(6429):515-521.
-
(1993)
Nature
, vol.363
, Issue.6429
, pp. 515-521
-
-
Rouleau, G.A.1
Merel, P.2
Lutchman, M.3
Sanson, M.4
Zucman, J.5
Marineau, C.6
Hoang-Xuan, K.7
Demczuk, S.8
Desmaze, C.9
Plougastel, B.10
-
35
-
-
84944495904
-
A theory of the effects of fibre size in medullated nerve
-
Rushton W.A.H. A theory of the effects of fibre size in medullated nerve. J Physiol Lond 1951, 115:101-122.
-
(1951)
J Physiol Lond
, vol.115
, pp. 101-122
-
-
Rushton, W.A.H.1
-
36
-
-
0842329800
-
Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function
-
Surace E.I., Haipek C.A., Gutmann D.H. Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function. Oncogene 2004, 23(2):580-587.
-
(2004)
Oncogene
, vol.23
, Issue.2
, pp. 580-587
-
-
Surace, E.I.1
Haipek, C.A.2
Gutmann, D.H.3
-
37
-
-
33846349243
-
Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding
-
Thaxton C., Lopera J., Bott M., Baldwin M.E., Kalidas P., Fernandez-Valle C. Phosphorylation of the NF2 tumor suppressor in Schwann cells is mediated by Cdc42-Pak and requires paxillin binding. Mol Cell Neurosci 2007, 34(2):231-242.
-
(2007)
Mol Cell Neurosci
, vol.34
, Issue.2
, pp. 231-242
-
-
Thaxton, C.1
Lopera, J.2
Bott, M.3
Baldwin, M.E.4
Kalidas, P.5
Fernandez-Valle, C.6
-
38
-
-
42549093636
-
Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways
-
Thaxton C., Lopera J., Bott M., Fernandez-Valle C. Neuregulin and laminin stimulate phosphorylation of the NF2 tumor suppressor in Schwann cells by distinct protein kinase A and p21-activated kinase-dependent pathways. Oncogene 2008, 27(19):2705-2715.
-
(2008)
Oncogene
, vol.27
, Issue.19
, pp. 2705-2715
-
-
Thaxton, C.1
Lopera, J.2
Bott, M.3
Fernandez-Valle, C.4
-
39
-
-
33749532141
-
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS
-
Thurnherr T., Benninger Y., Wu X., Chrostek A., Krause S.M., Nave K.A., Franklin R.J., Brakebusch C., Suter U., Relvas J.B. Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. J Neurosci 2006, 26(40):10110-10119.
-
(2006)
J Neurosci
, vol.26
, Issue.40
, pp. 10110-10119
-
-
Thurnherr, T.1
Benninger, Y.2
Wu, X.3
Chrostek, A.4
Krause, S.M.5
Nave, K.A.6
Franklin, R.J.7
Brakebusch, C.8
Suter, U.9
Relvas, J.B.10
-
40
-
-
0027405720
-
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
-
others
-
Trofatter J.A., MacCollin M.M., Rutter J.L., Murrell J.R., Duyao M.P., Parry D.M., Eldridge R., Kley N., Menon A.G., Pulaski K., others A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 1993, 72(5):791-800.
-
(1993)
Cell
, vol.72
, Issue.5
, pp. 791-800
-
-
Trofatter, J.A.1
MacCollin, M.M.2
Rutter, J.L.3
Murrell, J.R.4
Duyao, M.P.5
Parry, D.M.6
Eldridge, R.7
Kley, N.8
Menon, A.G.9
Pulaski, K.10
-
41
-
-
0037059807
-
P21-activated kinase links Rac/Cdc42 signaling to merlin
-
Xiao G.H., Beeser A., Chernoff J., Testa J.R. p21-activated kinase links Rac/Cdc42 signaling to merlin. J Biol Chem 2002, 277(2):883-886.
-
(2002)
J Biol Chem
, vol.277
, Issue.2
, pp. 883-886
-
-
Xiao, G.H.1
Beeser, A.2
Chernoff, J.3
Testa, J.R.4
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