Role of integrins in peripheral nerves and hereditary neuropathies

NeuroMolecular Medicine

Volumn 8, Issue 1-2, 2006, Pages 191-204

  Berti, Caterina ^a   Nodari, Alessandro ^a   Wrabetz, Lawrence ^a   Feltri, Maria Laura ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Conditional mutagenesis; Integrins; Laminin; MDC1A; Schwann cell

Indexed keywords

BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR; INTEGRIN; LAMININ; MEMBRANE PROTEIN; RHO FACTOR;

CELL ADHESION; CELL MIGRATION; GENE MUTATION; HUMAN; MUTAGENESIS; MYELINATION; NERVE GROWTH; NEURAL CREST CELL; NEUROPATHY; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NERVOUS SYSTEM; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SCHWANN CELL; SIGNAL TRANSDUCTION;

EID: 33745229355     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1385/NMM:8:1-2:191     Document Type: Review

References (96)

1. Amici S. A. and Notterpek L. (2005) Peripheral myelin protein 22 forms a complex with beta4 integrin in the Schwann cell membrane. Am. So. Neurosci. Abstr. 94(S1), 50.
2. Bilozur M. E. and Hay E. D. (1988) Neural crest migration in 3D extracellular matrix utilizes laminin, fibronectin, or collagen. Dev. Biol. 125, 19-33.
3. Bokel C. and Brown N. H. (2002) Integrins in development: moving on, responding to, and sticking to the extracellular matrix. Dev. Cell 3, 311-321.
4. Bradley W. G., Jaros E., and Jenkison M. (1977) The nodes of Ranvier in the nerves of mice with muscular dystrophy. J. Neuropathol. Exp. Neurol. 36, 797-806.
5. Bronner-Fraser M. (1993) Neural crest cell migration in the developing embryo. Trends Cell Biol. 3, 392-397.
6. Bunge M. B. (1993) Schwann cell regulation of extracellular matrix biosynthesis and assembly, In: Dyck P. J., Thomas P. K., Griffin J., Low P. A., and Poduslo J. F. (eds.). Peripheral Neuropathy, Philadelphia: W.B. Saunders, pp. 299-316.
7. Chen Z. L. and Strickland S. (2003) Laminin gammal is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve. J. Cell Biol. 163, 889-899.
8. Chen L. M., Bailey D., and Fernandez-Valle C. (2000) Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells. J. Neurosci. 20, 3776-3784.
9. Chernousov M. A. and Carey D. J. (2000) Schwann cell extracellular matrix molecules and their receptors. Histol. Histopathol. 15, 593-601.
10. Clegg D. O., Wingerd K. L., Hikita S. T., and Tolhurst E. C. (2003) Integrins in the development, function and dysfunction of the nervous system. Front Biosci. 8d, 723-750.
11. Colognato H. and Yurchenco P. D. (2000) Form and function: the laminin family of heterotrimers. Dev. Dyn. 218, 213-234.
12. Colognato H., Winkelmann D. A., and Yurchenco P. D. (1999) Laminin polymerization induces a receptor-cytoskeleton network. J. Cell Biol. 145, 619-631.
13. De Calisto J., Araya C., Marchant L., Riaz C. F., and Mayor R. (2005) Essential role of non-canonical Wnt signalling in neural crest migration. Development 132, 2587-2597.
14. Desban N., Duband J. L. (1997) Avian neural crest cell migration on laminin: interaction of the alphalbetal integrin with distinct laminin-1 domains mediates different adhesive responses. J. Cell Sci. 110(Pt 21), 2729-2744.
15. Drubin D. G. and Nelson W. J. (1996) Origins of cell polarity. Cell 84,:335-344.
16. Duband J. L. and Thiery J. P. (1987) Distribution of laminin and collagens during avian neural crest development. Development 101, 461-478.
17. Erickson C. A. and Perris R. (1993) The role of cell-cell and cell-matrix interactions in the morphogenesis of the neural crest. Dev. Biol. 159, 60-74.
18. Ervasti J. M. and Campbell K. P. (1993) A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin. J. Cell Biol. 122, 809-823.
19. Eshed Y., Feinberg K., Poliak S., et al. (2005) Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier. Neuron 47, 215-229.
20. Feltri M. L. and Wrabetz L. (2005) Laminins and their receptors in Schwann cells and hereditary neuropathies. J. Peripher. Nerv. Syst. 10, 128-143.
21. Feltri M. L., Scherer S. S., Nemni R., et al. (1994) α4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent. Development 120, 1287-1301.
22. Feltri M. L., Graus Porta D., Previtali S. C., et al. (2002) Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons. J. Cell Biol. 156, 199-209.
23. Fernandez-Valle C., Gorman D., Gomez A. M., and Bunge M. B. (1997) Actin plays a role in both changes in cell shape and gene-expression associated with Schwann cell myelination. J. Neurosci. 17, 241-250.
24. Fernandez-Valle C., Gwynn L., Wood P. M., Carbonetto S., and Bunge M. B. (1994) Anti-beta 1 integrin antibody inhibits Schwann cell myelination. J. NeuroBiol. 25, 1207-1226.
25. Fernandez-Valle C., Tang Y., Ricard J., et al. (2002) Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology. Nat. Genet. 31, 354-362.
26. ffrench-Constant C. and Colognato H. (2004) Integrins: versatile integrators of extracellular signals. Trends Cell Biol. 14, 678-686.
27. Franzke C. W., Tasanen K., Schumann H., and Bruckner-Tuderman L. (2003) Collagenous transmembrane proteins: collagen XVII as a prototype. Matrix Biol. 22, 299-309.
28. Gammill L. S., Bronner-Fraser M. (2003) Neural crest specification: migrating into genomics. Nat. Rev. Neurosci. 4, 795-805.
29. Gardner H., Kreidberg J., Koteliansky V., and Jaenisch R. (1996) Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Dev. Biol. 175, 301-313.
30. Gatto C. L., Walker B. J., Lambert S. (2003) Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of Ranvier. J. Cell Biol. 162, 489-498.
31. Geiger B., Bershadsky A., Pankov R., and Yamada K. M. (2001) Transmembrane crosstalk between the extracellular matrix - cytoskeleton crosstalk. Nat. Rev. Mol. Cell Biol. 2, 793-805.
32. Giancotti F. G. (2000) Complexity and specificity of integrin signalling. Nat. Cell Biol. 2E, 13, 14.
33. Goutebroze L., Carnaud M., Denisenko N., Boutterin M. C., and Girault J. A. (2003) Syndecan-3 and syndecan-4 are enriched in Schwann cell perinodal processes. BMC Neurosci. 4, 29.
34. Haack H. and Hynes R. O. (2001) Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage. Dev. Biol. 233, 38-55.
35. Hagel M., George E. L., Kim A., et al. (2002) The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling. Mol. Cell Biol. 22, 901-915.
36. Helbling-Leclerc A., Zhang X., Topaloglu H., et al. (1995) Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy. Nat. Genet. 11, 216-218.
37. Henry M. D., Satz J. S., Brakebusch C., et al. (2001) Distinct roles for dystroglycan, β1 integrin and perlecan in cell surface laminin organization. J. Cell Sci. 114, 1137-1144.
38. Hynes R. O. (1992) Integrins: versatility, modulation, and signalling in cell adhesion. Cell 69, 11-25.
39. Hynes R. O. and Zhao Q. (2000) The evolution of cell adhesion. J. Cell Biol. 150F, 89-96.
40. Jaros E. and Bradley W. G. (1979) Atypical axon-Schwann cell relationships in the common peroneal nerve of the dystrophic mouse: an ultrastructural study. Neuropathol. Appl. Neurobiol. 5, 133-147.
41. Jessen K. R. and Mirsky R. (1997) Embryonic Schwann cell development: the biology of Schwann cell precursors and early Schwann cells. J. Anal. 191 (Part 4), 501-505.
42. Jessen K. R. and Mirsky R. (2004) Schwann cell development, In: Lazzarini R. A. (ed). Myelin Biology and Disorder, San Diego: Elsevier academic press, pp. 329-370.
43. Kil S. H., Lallier T., and Bronner-Fraser M. (1996) Inhibition of cranial neural crest adhesion in vitro and migration in vivo using integrin antisense oligonucleotides. Dev. Biol. 179, 91-101.
44. Lallier T. and Bronner-Fraser M. (1993) Inhibition of neural crest cell attachment by integrin antisense oligonucleotides. Science 259, 692-695.
45. Le Douarin N. M. and Ziller C. (1993) Plasticity in neural crest cell differentiation. Curr. Opin. Cell Biol. 5, 1036-1043.
46. Le Douarin N. M. and Kalcheim C. (1999) The neural crest, 2nd Edition. Cambridge: Cambridge University Press.
47. Lee J. W. and Juliano R. (2004) Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Mol. Cells 17, 188-202.
48. Lentz S. I., Miner J. H., Sanes J. R., and Snider W. D. (1997) Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons. J. Comp. Neurol. 378, 547-561.
49. Li R. (2005) Neuronal polarity: until GSK-3 do us part. Curr. Biol. 15, R198-200.
50. Liu J. P., Jessell T. M. (1998) A role for rhoB in the delamination of neural crest cells from the dorsal neural tube. Development 125, 5055-5067.
51. Maro G. S., Vermeren M., Voiculescu O., et al. (2004) Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS. Nat. Neurosci. 7, 930-938.
52. McCarthy R. A. and Hay E. D. (1991) Collagen I, laminin, and tenascin: ultrastructure and correlation with avian neural crest formation. Int. J. Dev. Biol. 35, 437-452.
53. Melendez-Vasquez C. V., Einheber S., and Salzer J. L. (2004) Rho kinase regulates schwann cell myelination and formation of associated axonal domains. J. Neurosci. 24, 3953-3963.
54. Milner R., Wilby M., Nishimura S., et al. (1997) Division of labor of Schwann cell integrins during migration on peripheral nerve extracellular matrix ligands. Dev. Biol. 185, 215-228.
55. Miner J. H. and Yurchenco P. D. (2004) Laminin functions in tissue morphogenesis. Annu. Rev. Cell Dev. Biol. 20, 255-284.
56. Miosge N. (2001) The ultrastructural composition of basement membranes in vivo. Histol. Histopathol. 16, 1239-1248.
57. Mirsky R. and Jessen K. R. (1999) The neurobiology of Schwann cells. Brain Pathol. 9, 293-311.
58. Nakagawa M., Miyagoe-Suzuki Y., Ikezoe K., et al. (2001) Schwann cell myelination occurred without basal lamina formation in laminin alpha2 chain-null mutant (dy3K/dy3K) mice. Glia 35, 101-110.
59. Obremski V. J., Hall A. M., and Fernandez-Valle C. (1998) Merlin, the neurofibromatosis type 2 gene product, and beta1 integrin associate in isolated and differentiating Schwann cells. J. Neurobiol. 37, 487-501.
60. Occhi S., Zambroni D., Del Carro U., et al. (2005) Both Laminin and Schwann cell Dystroglycan are necessary for proper clustering of Sodium Channels at Nodes of Ranvier. J. Neurosci. 25, 9418-9427.
61. Patton B. L., Miner J. H., Chiu A. Y., and Sanes J. R. (1997) Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J. Cell Biol. 139, 1507-1521.
62. Perris R. and Perissinotto D. (2000) Role of the extracellular matrix during neural crest cell migration. Mech. Dev. 95, 3-21.
63. Perris R., Paulsson M., and Bronner-Fraser M. (1989) Molecular mechanisms of avian neural crest cell migration on fibronectin and laminin. Dev. Biol. 136, 222-238.
64. Pietri T., Eder O., Breau M. A., et al. (2004) Conditional betal-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system. Development 131, 3871-3883.
65. Podratz J. L., Rodriguez E., and Windebank A. J. (2001) Role of the extracellular matrix in myelination of peripheral nerve. Glia 35, 35-40.
66. Podratz J. L., Rodriguez E.H., and Windebank A. J. (2004) Antioxidants are necessary for myelination of dorsal root ganglion neurons, in vitro. Glia. 45, 54-58.
67. Podratz J. L., Rodriguez E. H., DiNonno E. S., and Windebank A. J. (1998) Myelination by Schwann cells in the absence of extracellular matrix assembly. Glia. 23, 383-388.
68. Previtali S. C., Dina G., Nodari A., et al. (2003a) Schwann cells synthesize alpha7beta1 integrin which is dispensable for peripheral nerve development and myelination. Mol. Cell Neurosci. 23, 210-218.
69. Previtali S. C., Nodari A., Taveggia C., et al. (2003b) Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J. Neurosci. 23, 5520-5530.
70. Quattrini A., Previtali S., Feltri M. L., Canal N., Nemni R., and Wrabetz L. (1996) α-β integrin and other Schwann cell markers in axonal neuropathy. Glia 17, 294-306.
71. Rouleau G. A., Merel P., Lutchman M., et al. (1993) Alteration in a new gene encoding a putative membrane-organizing protein causes neurofibromatosis type 2. Nature 363, 515-521.
72. Rovasio R. A., Delouvee A., Yamada K. M., Timpl R., and Thiery J. P. (1983) Neural crest cell migration: requirements for exogenous fibronectin and high cell density. J. Cell Biol. 96, 462-473.
73. Saito F., Moore S. A., Barresi R., et al. (2003) Unique role of dystroglycan in peripheral nerve myelination, nodal structure, and sodium channel stabilization. Neuron 38, 747-758.
74. Salzer J. L. (2003) Polarized domains of myelinated axons. Neuron 40, 297-318.
75. Sanes J. R., Engvall E., Butkowski R., and Hunter D. D. (1990) Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J. Cell Biol. 111, 1685-1699.
76. Shaw R. J., Henry M., Solomon F., and Jacks T. (1998) RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts. Mol. Biol. Cell 9, 403-419.
77. Shaw R. J., Paez J. G., Curto M., et al. (2001) The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. Dev. Cell 1, 63-72.
78. Sherman D. L., Fabrizi C., Gillespie C. S., and Brophy P. J. (2001) Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy. Neuron 30, 677-687.
79. Stewart H. J., Turner D., Jessen K. R., and Mirsky R. (1997) Expression and regulation of alphalbetal integrinin Schwann cells. J. Neurobiol. 33, 914-928.
80. Strachan L. R. and Condic M. L. (2003) Neural crest motility and integrin regulation are distinct in cranial and trunk populations. Dev. Biol. 259, 288-302.
81. Strachan L. R. and Condic M. L. (2004) Cranial neural crest recycle surface integrins in a substratum-dependent manner to promote rapid motility. J. Cell Biol. 167, 545-554.
82. Sunada Y., Bernier S. M., Utani A., Yamada Y., and Campbell K. P. (1995) Identification of a novel mutant transcript of laminin alpha 2 chain gene responsible for muscular dystrophy and dysmyelination in dy2J mice. Hum. Mol. Genet. 4, 1055-1061.
83. Testaz S., Delannet M., and Duband J. (1999) Adhesion and migration of avian neural crest cells on fibronectin require the cooperating activities of multiple integrins of the (beta)1l and (beta)3 families. J. Cell Sci. 112(Part 24), 4715-4728.
84. Toyota B., Carbonetto S., and David S. (1990) A dual laminin/ collagen receptor acts in peripheral nerve regeneration. Proc. Natl. Acad. Sci. USA 87, 1319-1322.
85. Trapp B. D. and Kidd G. J. (2004) Structure of myelinated axon, In: Lazzarini R. A. (ed.), Myelin Biology and Disorder, San Diego: Elsevier academic press. pp. 19-22.
86. Trofatter J. A., MacCollin M. M., Rutter J. L., et al (1993) A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 75, 826.
87. Turner C. E. (2000) Paxillin interactions. J. Cell Sci. 113(Part 23), 4139-4140.
88. Vagnerova K. T., Tarumi Y. S., Proctor T. M., and Patton B. L. (2003) A specialized basal lamina at the node of Ranvier. Society of Neuroscience abstract, 2003.
89. van der Flier A. and Sonnenberg A. (2001) Function and interactions of integrins. Cell Tissue Res. 305, 285-298.
90. Wallquist W., Patarroyo M., Thams S., et al. (2002) Laminin chains in rat and human peripheral nerve: distribution and regulation during development and after axonal injury. J. Comp. Neurol. 454, 284-293.
91. Waxman S. G. and Bangalore L. (2004) Electrophysiologic consequences of myelination, In: Lazzarini R. A. (ed.), Myelin Biology and Disorder, San Diego: San Diego pp. 117-172.
92. Wrabetz L., Feltri M. L., Kleopa K. A., and Scherer S. (2004) Inherited neuropathies: clinical, genetic, and biological features, In: Lazzarini R. A. (ed.), Myelin Biology and Disorder. San Diego: Elsevier academic press. pp. 905-935.
93. Xu H., Wu X. R., Wewer U. M., and Engvall E. (1994) Murine muscular dystrophy caused by a mutation in the laminin alpha 2 (Lama2) gene. Nat. Genet. 8, 297-302.
94. Yang D., Bierman J., Tarumi Y. S., et al. (2005) Coordinate control of axon defasciculation and myelination by laminin-2 and -8. J. Cell Biol. 168(4), 655-666.
95. Yin Y., Kikkawa Y., Mudd J. L., Skarnes W. C., Sanes J. R., and Miner J. H. (2003) Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques. Genesis 36, 114-127.
96. Yu W. M., Feltri M. L., Wrabetz L., Strickland S., and Chen Z. L. (2005) Schwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation. J. Neurosci. 25, 4463-4472.