-
1
-
-
34447623358
-
Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells
-
Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF. (2005). Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells. Breast Cancer Res 7: R965-R974.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Baugher, P.J.1
Krishnamoorthy, L.2
Price, J.E.3
Dharmawardhane, S.F.4
-
2
-
-
0033579464
-
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
-
DOI 10.1006/jmbi.1999.3310
-
Blom N, Gammeltoft S, Brunak S. (1999). Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol 294: 1351-1362. (Pubitemid 30008805)
-
(1999)
Journal of Molecular Biology
, vol.294
, Issue.5
, pp. 1351-1362
-
-
Blom, N.1
Gammeltoft, S.2
Brunak, S.3
-
3
-
-
28344456263
-
Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion
-
DOI 10.1038/sj.onc.1208909, PII 1208909
-
Chan AY, Coniglio SJ, Chuang Y-y, Michaelson D, Knaus UG, Philips MR et al. (2005). Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene 24: 7821-7829. (Pubitemid 41715188)
-
(2005)
Oncogene
, vol.24
, Issue.53
, pp. 7821-7829
-
-
Chan, A.Y.1
Coniglio, S.J.2
Chuang, Y.-Y.3
Michaelson, D.4
Knaus, U.G.5
Philips, M.R.6
Symons, M.7
-
4
-
-
0242391293
-
Application of Random Peptide Phage Display to the Study of Nuclear Hormone Receptors
-
DOI 10.1016/S0076-6879(03)64007-3
-
Chang CY, Norris JD, Jansen M, Huang HJ, McDonnell DP. (2003). Application of random peptide phage display to the study of nuclear hormone receptors. Methods Enzymol 364: 118-142. (Pubitemid 37408444)
-
(2003)
Methods in Enzymology
, vol.364
, pp. 118-142
-
-
Chang, C.-Y.1
Norris, J.D.2
Jansen, M.3
Huang, H.-J.4
McDonnell, D.P.5
-
5
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
DOI 10.1073/pnas.0409462102
-
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T et al. (2005). Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA 102: 3738-3743. (Pubitemid 40354681)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.10
, pp. 3738-3743
-
-
Chang, H.Y.1
Nuyten, D.S.A.2
Sneddon, J.B.3
Hastie, T.4
Tibshirani, R.5
Sorlie, T.6
Dai, H.7
He, Y.D.8
Van'T Veer, L.J.9
Bartelink, H.10
Van De Rijn, M.11
Brown, P.O.12
Van De Vijver, M.J.13
-
6
-
-
71749098088
-
ELM: The status of the 2010 eukaryotic linear motif resource
-
Gould CM, Diella F, Via A, Puntervoll P, Gemund C, Chabanis-Davidson S et al. (2010). ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Res 38: D167-D180.
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Gould, C.M.1
Diella, F.2
Via, A.3
Puntervoll, P.4
Gemund, C.5
Chabanis-Davidson, S.6
-
7
-
-
33646238716
-
MTA1, a transcriptional activator of breast cancer amplified sequence 3
-
Gururaj AE, Singh RR, Rayala SK, Holm C, den Hollander P, Zhang H et al. (2006). MTA1, a transcriptional activator of breast cancer amplified sequence 3. Proc Natl Acad Sci USA 103: 6670-6675.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6670-6675
-
-
Gururaj, A.E.1
Singh, R.R.2
Rayala, S.K.3
Holm, C.4
Den Hollander, P.5
Zhang, H.6
-
8
-
-
33947307480
-
Rac1 and rac3 have opposing functions in cell adhesion and differentiation of neuronal cells
-
DOI 10.1242/jcs.03364
-
Hajdo-Milasinovic A, Ellenbroek SIJ, van Es S, van der Vaart B, Collard JG (2007). Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells. J Cell Sci 120: 555-566. (Pubitemid 46437890)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.4
, pp. 555-566
-
-
Hajdo-Milasinovic, A.1
Ellenbroek, S.I.J.2
Van Es, S.3
Van Der Vaart, B.4
Collard, J.G.5
-
9
-
-
0028233383
-
Estrogen receptor-associated proteins: Possible media-tors of hormone-induced transcription
-
Halachmi S, Marden E, Martin G, MacKay H, Abbondanza C, Brown M. (1994). Estrogen receptor-associated proteins: possible media-tors of hormone-induced transcription. Science 264: 1455-1458.
-
(1994)
Science
, vol.264
, pp. 1455-1458
-
-
Halachmi, S.1
Marden, E.2
Martin, G.3
MacKay, H.4
Abbondanza, C.5
Brown, M.6
-
10
-
-
30344479480
-
Coregulators in nuclear estrogen receptor action: From concept to therapeutic targeting
-
DOI 10.1124/mi.5.6.7
-
Hall JM, McDonnell DP. (2005). Co-regulators in nuclear estrogen receptor action: from concept to therapeutic targeting. Mol Interv 5: 343-357. (Pubitemid 43060715)
-
(2005)
Molecular Interventions
, vol.5
, Issue.6
, pp. 343-357
-
-
Hall, J.M.1
McDonnell, D.P.2
-
11
-
-
33747156647
-
A protocol for combined Photinus and Renilla luciferase quantification compatible with protein assays
-
DOI 10.1016/j.ab.2006.04.046, PII S0003269706003071
-
Hampf M, Gossen M. (2006). A protocol for combined photinus and renilla luciferase quantification compatible with protein assays. Anal Biochem 356: 94-99. (Pubitemid 44232725)
-
(2006)
Analytical Biochemistry
, vol.356
, Issue.1
, pp. 94-99
-
-
Hampf, M.1
Gossen, M.2
-
12
-
-
33749457974
-
Estrogen receptor positive breast cancer metastasis: Altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes
-
DOI 10.1158/0008-5472.CAN-06-1769
-
Harrell JC, Dye WW, Allred DC, Jedlicka P, Spoelstra NS, Sartorius CA et al. (2006). Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Res 66: 9308-9315. (Pubitemid 44521153)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9308-9315
-
-
Harrell, J.C.1
Dye, W.W.2
Allred, D.C.3
Jedlicka, P.4
Spoelstra, N.S.5
Sartorius, C.A.6
Horwitz, K.B.7
-
13
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
Heasman SJ, Ridley AJ. (2008). Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9: 690-701.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
14
-
-
34447523339
-
Estrogen receptors: How do they signal and what are their targets
-
DOI 10.1152/physrev.00026.2006
-
Heldring N, Pike A, Andersson S, Matthews J, Cheng G, Hartman J et al. (2007). Estrogen receptors: how do they signal and what are their targets. Physiol Rev 87: 905-931. (Pubitemid 47084672)
-
(2007)
Physiological Reviews
, vol.87
, Issue.3
, pp. 905-931
-
-
Heldring, N.1
Pike, A.2
Andersson, S.3
Matthews, J.4
Cheng, G.5
Hartman, J.6
Tujague, M.7
Strom, A.8
Treuter, E.9
Warner, M.10
Gustafsson, J.-A.11
-
16
-
-
77950633401
-
New strategies in estrogen receptor-positive breast cancer
-
Johnston SR. (2010). New strategies in estrogen receptor-positive breast cancer. Clin Cancer Res 16: 1979-1987.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1979-1987
-
-
Johnston, S.R.1
-
17
-
-
58149193222
-
Human protein reference database\2009 update
-
Keshava Prasad TS, Goel R, Kandasamy K, Keerthikumar S, Kumar S, Mathivanan S et al. (2009). Human protein reference database\2009 update. Nucleic Acids Res 37: D767-D772.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Keshava Prasad, T.S.1
Goel, R.2
Kandasamy, K.3
Keerthikumar, S.4
Kumar, S.5
Mathivanan, S.6
-
18
-
-
17144416838
-
The clinical relevance of steroid hormone receptor corepressors
-
DOI 10.1158/1078-0432.CCR-04-1276
-
Kumar R, Gururaj AE, Vadlamudi RK, Rayala SK (2005). The clinical relevance of steroid hormone receptor co-repressors. Clin Cancer Res 11: 2822-2831. (Pubitemid 40525180)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.8
, pp. 2822-2831
-
-
Kumar, R.1
Gururaj, A.E.2
Vadlamudi, R.K.3
Rayala, S.K.4
-
19
-
-
67649210289
-
The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer
-
Lahusen T, Henke RT, Kagan BL, Wellstein A, Riegel AT. (2009). The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer. Breast Cancer Res Treat 116: 225-237.
-
(2009)
Breast Cancer Res Treat
, vol.116
, pp. 225-237
-
-
Lahusen, T.1
Henke, R.T.2
Kagan, B.L.3
Wellstein, A.4
Riegel, A.T.5
-
20
-
-
28144433667
-
Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor α
-
DOI 10.1210/me.2005-0178
-
Leong H, Sloan JR, Nash PD, Greene GL. (2005). Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor alpha. Mol Endocrinol 19: 2930-2942. (Pubitemid 41697712)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.12
, pp. 2930-2942
-
-
Leong, H.1
Sloan, J.R.2
Nash, P.D.3
Greene, G.L.4
-
21
-
-
0242489239
-
Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions
-
DOI 10.1159/000073751
-
Leung K, Nagy A, Gonzalez-Gomez I, Groffen J, Heisterkamp N, Kaartinen V. (2003). Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions. Cells Tissues Organs (Print) 175: 72-83. (Pubitemid 37409851)
-
(2003)
Cells Tissues Organs
, vol.175
, Issue.2
, pp. 72-83
-
-
Leung, K.1
Nagy, A.2
Gonzalez-Gomez, I.3
Groffen, J.4
Heisterkamp, N.5
Kaartinen, V.6
-
22
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
DOI 10.1038/nature03799
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD et al. (2005). Genes that mediate breast cancer metastasis to lung. Nature 436: 518-524. (Pubitemid 41112921)
-
(2005)
Nature
, vol.436
, Issue.7050
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
Viale, A.7
Olshen, A.B.8
Gerald, W.L.9
Massague, J.10
-
23
-
-
0034602690
-
Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway
-
DOI 10.1073/pnas.97.1.185
-
Mira JP, Benard V, Groffen J, Sanders LC, Knaus UG (2000). Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci USA 97: 185-189. (Pubitemid 30055805)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.1
, pp. 185-189
-
-
Mira, J.-P.1
Benard, V.2
Groffen, J.3
Sanders, L.C.4
Knaus, U.G.5
-
24
-
-
33646033137
-
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen
-
Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G et al. (2006). A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 124: 1283-1298.
-
(2006)
Cell
, vol.124
, pp. 1283-1298
-
-
Moffat, J.1
Grueneberg, D.A.2
Yang, X.3
Kim, S.Y.4
Kloepfer, A.M.5
Hinkle, G.6
-
25
-
-
0034595096
-
Estrogen receptors: How do they control reproductive and nonreproductive functions?
-
DOI 10.1006/bbrc.2000.2214
-
Muramatsu M, Inoue S. (2000). Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 270: 1-10. (Pubitemid 30440384)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.270
, Issue.1
, pp. 1-10
-
-
Muramatsu, M.1
Inoue, S.2
-
26
-
-
0030745396
-
Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4
-
Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J et al. (1997). Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Mol Cell Biol 17: 5338-5347. (Pubitemid 27357632)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.9
, pp. 5338-5347
-
-
Neuman, E.1
Ladha, M.H.2
Lin, N.3
Upton, T.M.4
Miller, S.J.5
Direnzo, J.6
Pestell, R.G.7
Hinds, P.W.8
Dowdy, S.F.9
Brown, M.10
Ewen, M.E.11
-
27
-
-
0035423119
-
Re-expression of estrogen receptor α in estrogen receptor α-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling anal growth
-
Oesterreich S, Zhang P, Guler RL, Sun X, Curran EM, Welshons WV et al. (2001). Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth. Cancer Res 61: 5771-5777. (Pubitemid 32769093)
-
(2001)
Cancer Research
, vol.61
, Issue.15
, pp. 5771-5777
-
-
Oesterreich, S.1
Zhang, P.2
Guler, R.L.3
Sun, X.4
Curran, E.M.5
Welshons, W.V.6
Osborne, C.K.7
Lee, A.V.8
-
28
-
-
45549094636
-
Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases
-
Onesto C, Shutes A, Picard V, Schweighoffer F, Der CJ. (2008). Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. Methods Enzymol 439: 111-129.
-
(2008)
Methods Enzymol
, vol.439
, pp. 111-129
-
-
Onesto, C.1
Shutes, A.2
Picard, V.3
Schweighoffer, F.4
Der, C.J.5
-
29
-
-
57749083496
-
Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements
-
Pan YF, Wansa KD, Liu MH, Zhao B, Hong SZ, Tan PY et al. (2008). Regulation of estrogen receptor-mediated long range transcription via evolutionarily conserved distal response elements. J Biol Chem 283: 32977-32988.
-
(2008)
J Biol Chem
, vol.283
, pp. 32977-32988
-
-
Pan, Y.F.1
Wansa, K.D.2
Liu, M.H.3
Zhao, B.4
Hong, S.Z.5
Tan, P.Y.6
-
30
-
-
33644699019
-
Lessons learnt from structural studies of the oestrogen receptor
-
DOI 10.1016/j.beem.2005.09.002, PII S1521690X05000692, Endocrine Disrupters
-
Pike AC (2006). Lessons learnt from structural studies of the oestrogen receptor. Best Pract Res Clin Endocrinol Metab 20: 1-14. (Pubitemid 43328570)
-
(2006)
Best Practice and Research: Clinical Endocrinology and Metabolism
, vol.20
, Issue.1
, pp. 1-14
-
-
Pike, A.C.W.1
-
31
-
-
0036550954
-
The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells
-
Prest SJ, May FE, Westley BR. (2002). The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells. FASEB J 16: 592-594.
-
(2002)
FASEB J
, vol.16
, pp. 592-594
-
-
Prest, S.J.1
May, F.E.2
Westley, B.R.3
-
32
-
-
32944473985
-
P21-activated kinase 1 regulation of estrogen receptor-α activation involves serine 305 activation linked with serine 118 phosphorylation
-
DOI 10.1158/0008-5472.CAN-05-2922
-
Rayala SK, Talukder AH, Balasenthil S, Tharakan R, Barnes CJ, Wang RA et al. (2006). P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. Cancer Res 66: 1694-1701. (Pubitemid 43259954)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1694-1701
-
-
Rayala, S.K.1
Talukder, A.H.2
Balasenthil, S.3
Tharakan, R.4
Barnes, C.J.5
Wang, R.-A.6
Aldaz, M.7
Khan, S.8
Kumar, R.9
-
33
-
-
22744446856
-
Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer
-
DOI 10.1038/sj.onc.1208646
-
Saji S, Kawakami M, Hayashi S, Yoshida N, Hirose M, Horiguchi S et al. (2005). Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene 24: 4531-4539. (Pubitemid 41032616)
-
(2005)
Oncogene
, vol.24
, Issue.28
, pp. 4531-4539
-
-
Saji, S.1
Kawakami, M.2
Hayashi, S.-I.3
Yoshida, N.4
Hirose, M.5
Horiguchi, S.-I.6
Itoh, A.7
Funata, N.8
Schreiber, S.L.9
Yoshida, M.10
Toi, M.11
-
34
-
-
78049352549
-
Estrogen receptor-\{alpha\} promotes breast cancer cell motility and invasion via focal adhesion kinase and n-wasp
-
Sanchez AM, Flamini MI, Baldacci C, Goglia L, Genazzani AR, Simoncini T. (2010). Estrogen receptor-\{alpha\} promotes breast cancer cell motility and invasion via focal adhesion kinase and n-wasp. Mol Endocrinol 24: 2114-2125.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 2114-2125
-
-
Sanchez, A.M.1
Flamini, M.I.2
Baldacci, C.3
Goglia, L.4
Genazzani, A.R.5
Simoncini, T.6
-
35
-
-
73549115097
-
The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2
-
Sandrock K, Bielek H, Schradi K, Schmidt G, Klugbauer N. (2010). The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2. Traffic 11: 198-209.
-
(2010)
Traffic
, vol.11
, pp. 198-209
-
-
Sandrock, K.1
Bielek, H.2
Schradi, K.3
Schmidt, G.4
Klugbauer, N.5
-
36
-
-
0037192501
-
Molecular determinants for the tissue specificity of SERMs
-
DOI 10.1126/science.1068537
-
Shang Y, Brown M. (2002). Molecular determinants for the tissue specificity of SERMs. Science 295: 2465-2468. (Pubitemid 34270263)
-
(2002)
Science
, vol.295
, Issue.5564
, pp. 2465-2468
-
-
Shang, Y.1
Brown, M.2
-
37
-
-
0033637703
-
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
-
Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M. (2000). Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 103: 843-852.
-
(2000)
Cell
, vol.103
, pp. 843-852
-
-
Shang, Y.1
Hu, X.2
Direnzo, J.3
Lazar, M.A.4
Brown, M.5
-
38
-
-
33644774386
-
CRIPak, a novel endogenous Pak1 inhibitor
-
DOI 10.1038/sj.onc.1209172, PII 1209172
-
Talukder AH, Meng Q, Kumar R. (2006). CRIPak, a novel endogenous Pak1 inhibitor. Oncogene 25: 1311-1319. (Pubitemid 43336459)
-
(2006)
Oncogene
, vol.25
, Issue.9
, pp. 1311-1319
-
-
Talukder, A.H.1
Meng, Q.2
Kumar, R.3
-
39
-
-
26244462371
-
Breast cancer metastasis to the central nervous system
-
Weil RJ, Palmieri DC, Bronder JL, Stark AM, Steeg PS. (2005). Breast cancer metastasis to the central nervous system. Am J Pathol 167: 913-920. (Pubitemid 41416243)
-
(2005)
American Journal of Pathology
, vol.167
, Issue.4
, pp. 913-920
-
-
Weil, R.J.1
Palmieri, D.C.2
Bronder, J.L.3
Stark, A.M.4
Steeg, P.S.5
-
40
-
-
44849124445
-
Extracellular matrix, Rac1 signaling, and estrogen-induced proliferation in MCF-7 breast cancer cells
-
DOI 10.1007/s10549-007-9719-0
-
Xie JW, Haslam SZ. (2008). Extracellular matrix, Rac1 signaling, and estrogen-induced proliferation in MCF-7 breast cancer cells. Breast Cancer Res Treat 110: 257-268. (Pubitemid 351793875)
-
(2008)
Breast Cancer Research and Treatment
, vol.110
, Issue.2
, pp. 257-268
-
-
Xie, J.-W.1
Haslam, S.Z.2
|