Cytotoxic and antineoplastic activity of timosaponin A-III for human colon cancer cells

Journal of Natural Products

Volumn 74, Issue 4, 2011, Pages 701-706

  Kang, You Jin ^a   Chung, Hwa Jin ^b   Nam, Joo Won ^a   Park, Hyen Joo ^b   Seo, Eun Kyoung ^a   Kim, Yeong Shik ^b   Lee, Dongho ^c   Lee, Sang Kook ^b  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

^c Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLINE; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; SAPONIN DERIVATIVE; TIMOSAPONIN A III; UNCLASSIFIED DRUG;

ANEMARRHENA ASPHODELOIDES; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; COLON CANCER; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INDUCTION; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RHIZOME; TREATMENT DURATION; TUMOR XENOGRAFT;

ANEMARRHENA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICE; MICE, NUDE; MOLECULAR STRUCTURE; POLY(ADP-RIBOSE) POLYMERASES; RHIZOME; SAPONINS; STEROIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANEMARRHENA ASPHODELOIDES; MURINAE; MUS MUSCULUS;

EID: 79955412969     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np1007735     Document Type: Article

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