Mechanisms involved in regulation of osteoclastic differentiation by mechanical stress-loaded osteoblasts

Biochemical and Biophysical Research Communications

Volumn 408, Issue 1, 2011, Pages 103-109

  Kaneuji, Takeshi ^a   Ariyoshi, Wataru ^a   Okinaga, Toshinori ^a   Toshinaga, Akihiro ^a   Takahashi, Tetsu ^a   Nishihara, Tatsuji ^a  

^a KYUSHU DENTAL COLLEGE   (Japan)

Author keywords

Mechanical stress; Non canonical Wnt pathway; Osteoclastogenesis; Osteoprotegerin

Indexed keywords

I KAPPA B ALPHA; MESSENGER RNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROTEIN P50; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL CULTURE; COMPRESSION; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; INCUBATION TEMPERATURE; MECHANICAL STRESS; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CULTURE MEDIA, CONDITIONED; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MICE; NF-KAPPA B; OSTEOBLASTS; OSTEOCLASTS; OSTEOPROTEGERIN; RANK LIGAND; STRESS, MECHANICAL; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 79955407808     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.03.128     Document Type: Article

References (38)

1. Chau J.F., Leong W.F., Li B. Signaling pathways governing osteoblast proliferation, differentiation and function. Histol. Histopathol. 2009, 24:1593-1606.
2. Liedert A., Wagner L., Seefried L., Ebert R., Jakob F., Ignatius A. Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells. Biochem. Biophys. Res. Commun. 2010, 394:755-759.
3. Kanzaki H., Chiba M., Shimizu Y., Mitani H. Periodontal ligament cells under mechanical stress induce osteoclastogenesis by receptor activator of nuclear factor κB ligand up-regulation via prostaglandin E2 synthesis. J. Bone Miner Res. 2002, 17:210-220.
4. Ichimiya H., Takahashi T., Ariyoshi W., Takano H., Matayoshi T., Nishihara T. Compressive mechanical stress promotes osteoclast formation through RANKL expression on synovial cells. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2007, 103:334-341.
5. Kreja L., Liedert A., Hasni S., Claes L., Ignatius A. Mechanical regulation of osteoclastic genes in human osteoblasts. Biochem. Biophys. Res. Commun. 2008, 368:582-587.
6. Schneeweis L.A., Willard D., Milla M.E. Functional dissection of osteoprotegerin and its interaction with receptor activator of NF-κB ligand. J. Biol. Chem. 2005, 280:41155-41164.
7. Wong B.R., Josien R., Lee S.Y., Vologodskaia M., Steinman R.M., Choi Y. The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor. J. Biol. Chem. 1998, 273:28355-28359.
8. Walsh M.C., Kim G.K., Maurizio P.L., Molnar E.E., Choi Y. TRAF6 autoubiquitination-independent activation of the NF-κB and MAPK pathways in response to IL-1 and RANKL. PLoS One 2008, 3:e4064.
9. Mizukami J., Takaesu G., Akatsuka H., Sakurai H., Ninomiya-Tsuji J., Matsumoto K., Sakurai N. Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase through a signaling complex containing RANK TAB2 and TRAF6. Mol. Cell Biol. 2002, 22:992-1000.
10. Jimi E., Nakamura I., Ikebe T., Akiyama S., Takahashi N., Suda T. Activation of NF-kappaB is involved in the survival of osteoclasts promoted by interleukin-1. J. Biol. Chem. 1998, 273:8795-8805.
11. Wei S., Teitelbaum S.L., Wang M.W., Ross F.P. Receptor activator of nuclear factor-κB ligand activates nuclear factor-κB in osteoclast precursors. Endocrinology 2001, 142:1290-1295.
12. Clevers H. Wnt/β-catenin signaling in development disease. Cell 2006, 127:469-480.
13. Baron R., Rawadi G. Targeting the Wnt/β-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology 2007, 148:2635-2643.
14. Gregory C.A., Green A., Lee N., Rao A., Gunn W. The promise of canonical Wnt signaling modulators in enhancing bone repair. Drug News Perspect 2006, 19:445-452.
15. Bodine P.V. Wnt signaling control of bone cell apoptosis. Cell Res 2008, 18:248-253.
16. Minear S., Leucht P., Jiang J., Liu B., Zeng A., Fuerer C., Nusse R., Helms J.A. Wnt proteins promote bone regeneration. Sci. Transl. Med. 2010, 2:29-30.
17. Glass D.A., Bialek P., Ahn J.D., Starbuck M., Patel M.S., Clevers H., Taketo M.M., Long F., McMahon A.P., Lang R.A., Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev. Cell 2005, 8:751-764.
18. Yu HC, Wu TC, Chen MR, Liu SW, Chen JH, Lin KM. Mechanical stretching induces osteoprotegerin in differentiating C2C12 precursor cells through noncanonical Wnt pathways. J. Bone Miner Res. 25 (2010) 1128-1137.
19. Toshinaga A., Hosokawa R., Okinaga T., Masaki C., Tsujisawa T., Nishihara T. Inflammatory response in epithelial cells induced by mechanical stress is suppressed by hyaluronic acid. Inflammatory and Regeneration 2009, 30:120-127.
20. Shinmyouzu K., Takahashi T., Ariyoshi W., Ichimiya H., Kanzaki S., Nishihara T. Dermatan sulfate inhibits osteoclast formation by binding to receptor activator of NF-κB ligand. Biochem. Biophys. Res. Commun. 2007, 354:447-452.
21. Rasmussen T.B., Uttenthal A., de Stricker K., Belák S., Storgaard T. Development of a novel quantitative real-time RT-PCR assay for the simultaneous detection of all serotypes of foot-and-mouth disease virus. Arch. Virol. 2003, 148:2005-2021.
22. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic. Acids Res. 2001, 29:e45.
23. Liedert A., Kaspar D., Blakytny R., Claes L., Ignatius A. Signal transduction pathways involved in mechanotransduction in bone cells. Biochem. Biophys. Res. Commun. 2006, 349:1-5.
24. Iqbal J., Zaidi M. Molecular regulation of mechanotransduction. Biochem. Biophys. Res. Commun. 2005, 328:751-755.
25. You L., Temiyasathit S., Lee P., Kim C.H., Tummala P., Yao W., Kingery W., Malone A.M., Kwon R.Y., Jacobs C.R. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading. Bone 2008, 42:172-179.
26. Rubin J., Murphy T., Nanes M.S., Fan X. Mechanical strain inhibits expression of osteoclast differentiation factor by murine stromal cells. Am. J. Physiol. Cell. Physiol. 2000, 278:C1126-1132.
27. Yamaguchi M., Aihara N., Kojima T., Kasai K. RANKL increase in compressed periodontal ligament cells from root resorption. J. Dent. Res. 2006, 85:751-756.
28. Kurata K., Heino T.J., Higaki H., Väänänen H.K. Bone marrow cell differentiation induced by mechanically damaged osteocytes in 3D gel-embedded culture. J. Bone Miner Res. 2006, 21:616-625.
29. Araujo R.M.S., Oba Y., Moriyama K. Identification of genes related to mechanical stress in human periodontal ligament cells using microarray analysis. J. Periodontal Res. 2007, 42:15-22.
30. Ji J.D., Park-Min K.H., Shen Z., Fajardo R.J., Goldring S.R., McHugh K.P., Ivashkiv L.B. Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN-gamma in human osteoclast precursors. J. Immunol. 2009, 183:7223-7233.
31. Darnay B.G., Ni J., Moore P.A., Aggarwal B.B. Activation of NF-κB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-κB-inducing kinase. J. Biol. Chem. 1999, 274:7724-7731.
32. Li C., Yang Z., Li Z., Ma Y., Zhang L., Zheng C., Qiu W., Wu X., Wang X., Li H., Tang J., Qian M., Li D., Wang P., Luo J., Liu M. Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways. J. Bone Miner Res. 2011, 26:644-656.
33. Moynagh P.N. The NF-κB pathway. J. Cell Sci. 2005, 118:4589-4592.
34. Rubin J., Murphy T.C., Fan X., Goldschmidt M., Taylor W.R. Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells. J. Bone Miner Res. 2002, 17:1452-1460.
35. Mehrotra M., Saegusa M., Wadhwa S., Voznesensky O., Peterson D., Pilbeam C. Fluid flow induces Rankl expression in primary murine calvarial osteoblasts. J. Cell Biochem. 2006, 98:1271-1283.
36. Kook S.H., Son Y.O., Hwang J.M., Kim E.M., Lee C.B., Jeon Y.M., Kim J.G., Lee J.C. Mechanical force inhibits osteoclastogenic potential of human periodontal ligament fibroblasts through OPG production and ERK-mediated signaling. J. Cell Biochem. 2009, 106:1009-1010.
37. Sato K., Suematsu A., Nakashima T., Takemoto-Kimura S., Aoki K., Morishita Y., Asahara H., Ohya K., Yamaguchi A., Takai T., Kodama T., Chatila T.A., Bito H., Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat. Med. 2006, 12:1410-1416.
38. Hirotani H., Tuohy N.A., Woo J.T., Stern P.H., Clipstone N.A. The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264. 7 cells. J Biol Chem 2004, 279:13984-13992.