Reduced serum content and increased matrix stiffness promote the cardiac myofibroblast transition in 3D collagen matrices

Cardiovascular Pathology

Volumn 20, Issue 6, 2011, Pages 325-333

  Galie, Peter A ^a   Westfall, Margaret V ^b   Stegemann, Jan P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Collagen gel; Fibrosis; Myofibroblast; Serum; Stiffness

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN TYPE 3; COLLAGEN TYPE 3 ALPHA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; FIBROBLAST; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HYDROGEL; IMMUNOHISTOCHEMISTRY; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SCAR FORMATION; STELLATE CELL; YOUNG MODULUS;

ACTINS; ANIMALS; ANIMALS, NEWBORN; CELL CULTURE TECHNIQUES; CELL SHAPE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; COLLAGEN; CULTURE MEDIA; ELASTIC MODULUS; FEEDBACK, PHYSIOLOGICAL; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; GENETIC MARKERS; HYDROGELS; IMMUNOHISTOCHEMISTRY; MYOCARDIUM; MYOFIBROBLASTS; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERUM; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; VISCOSITY;

EID: 79955407134     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2010.10.001     Document Type: Article

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