메뉴 건너뛰기




Volumn 31, Issue 2, 2011, Pages 407-419

Adjuvants and Vector Systems for Allergy Vaccines

Author keywords

Adjuvants; Allergy vaccine; Immunopotentiation; Immunotherapy; Mucosal immunity; Vector system

Indexed keywords

ACETYLSALICYLIC ACID; ALLERGEN; ALLERGY VACCINE; ALUMINUM HYDROXIDE; ANTIALLERGIC AGENT; BACTERIAL TOXIN; CALCINEURIN INHIBITOR; CALCIUM PHOSPHATE; CHOLERA TOXIN; CYCLOSPORIN A; DEXAMETHASONE; DIHYDROXYCOLECALCIFEROL; GLUCOCORTICOID; IMIDAZOQUINOLINE DERIVATIVE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; IMMUNOLOGICAL ADJUVANT; LIPOSOME; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POLYGLACTIN; PROBIOTIC AGENT; RAPAMYCIN; TACROLIMUS; UNCLASSIFIED DRUG; VIROSOME;

EID: 79955402717     PISSN: 08898561     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.iac.2011.03.001     Document Type: Review
Times cited : (33)

References (100)
  • 1
    • 0031736285 scopus 로고    scopus 로고
    • Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper
    • Bousquet J., Lockey R., Malling H.J. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. J Allergy Clin Immunol 1998, 102:558-562.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 558-562
    • Bousquet, J.1    Lockey, R.2    Malling, H.J.3
  • 2
    • 50249230114 scopus 로고
    • Prophylactic inoculation against hay fever
    • Noon L. Prophylactic inoculation against hay fever. Lancet 1911, 2:1572-1573.
    • (1911) Lancet , vol.2 , pp. 1572-1573
    • Noon, L.1
  • 3
    • 50249195230 scopus 로고
    • Further observations on the treatment of hay fever by hypodermic inoculations of pollen vaccine
    • Freeman J. Further observations on the treatment of hay fever by hypodermic inoculations of pollen vaccine. Lancet 1911, 2:814-817.
    • (1911) Lancet , vol.2 , pp. 814-817
    • Freeman, J.1
  • 4
    • 34548164520 scopus 로고    scopus 로고
    • Allergen immunotherapy: a practice parameter second update
    • Cox L., Li J.T., Nelson H.S., et al. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007, 120:25-85.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 25-85
    • Cox, L.1    Li, J.T.2    Nelson, H.S.3
  • 5
    • 0033549827 scopus 로고    scopus 로고
    • Long term clinical efficacy of grass pollen immunotherapy
    • Durham S.R., Walker S.M., Varga E., et al. Long term clinical efficacy of grass pollen immunotherapy. N Engl J Med 1999, 341:468-475.
    • (1999) N Engl J Med , vol.341 , pp. 468-475
    • Durham, S.R.1    Walker, S.M.2    Varga, E.3
  • 7
    • 4544370248 scopus 로고    scopus 로고
    • Aluminium hydroxide down-regulates T helper 2 responses by allergen-stimulated human peripheral blood mononuclear cells
    • Wilcock L.K., Francis J.N., Durham S.R. Aluminium hydroxide down-regulates T helper 2 responses by allergen-stimulated human peripheral blood mononuclear cells. Clin Exp Allergy 2004, 34:1373-1378.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1373-1378
    • Wilcock, L.K.1    Francis, J.N.2    Durham, S.R.3
  • 8
    • 33646391232 scopus 로고    scopus 로고
    • Novel ways for immune intervention in immunotherapy: mucosal allergy vaccines
    • Mascarell L., Van Overtvelt L., Moingeon P. Novel ways for immune intervention in immunotherapy: mucosal allergy vaccines. Immunol Allergy Clin North Am 2006, 26:283-306.
    • (2006) Immunol Allergy Clin North Am , vol.26 , pp. 283-306
    • Mascarell, L.1    Van Overtvelt, L.2    Moingeon, P.3
  • 9
    • 75849127328 scopus 로고    scopus 로고
    • Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009
    • Canonica G.W., Bousquet J., Casale T., et al. Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009. Allergy 2009, 64(Suppl 91):1-59.
    • (2009) Allergy , vol.64 , Issue.SUPPL 91 , pp. 1-59
    • Canonica, G.W.1    Bousquet, J.2    Casale, T.3
  • 11
    • 76049102867 scopus 로고    scopus 로고
    • Sublingual immunotherapy: certainties, unmet needs and future directions
    • Passalacqua G., Lombardi C., Troise C., et al. Sublingual immunotherapy: certainties, unmet needs and future directions. Eur Ann Allergy Clin Immunol 2009, 41:163-170.
    • (2009) Eur Ann Allergy Clin Immunol , vol.41 , pp. 163-170
    • Passalacqua, G.1    Lombardi, C.2    Troise, C.3
  • 13
    • 1942505745 scopus 로고    scopus 로고
    • Immunological foundations to the quest for new vaccine adjuvants
    • Burdin N., Guy B., Moingeon P. Immunological foundations to the quest for new vaccine adjuvants. BioDrugs 2004, 18:79-93.
    • (2004) BioDrugs , vol.18 , pp. 79-93
    • Burdin, N.1    Guy, B.2    Moingeon, P.3
  • 14
    • 0036324843 scopus 로고    scopus 로고
    • Delivery technologies for human vaccines
    • Moingeon P., de Taisne C., Almond J. Delivery technologies for human vaccines. Br Med Bull 2002, 62:29-44.
    • (2002) Br Med Bull , vol.62 , pp. 29-44
    • Moingeon, P.1    de Taisne, C.2    Almond, J.3
  • 16
    • 0037393717 scopus 로고    scopus 로고
    • Endotoxin content of standardized allergen vaccines
    • Trivedi B., Valerio C., Slater J.E. Endotoxin content of standardized allergen vaccines. J Allergy Clin Immunol 2003, 111:777-783.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 777-783
    • Trivedi, B.1    Valerio, C.2    Slater, J.E.3
  • 17
    • 60549110301 scopus 로고    scopus 로고
    • Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells
    • Barret N.A., Maekawa A., Rahman O.M., et al. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J Immunol 2009, 182:1119-1128.
    • (2009) J Immunol , vol.182 , pp. 1119-1128
    • Barret, N.A.1    Maekawa, A.2    Rahman, O.M.3
  • 18
    • 78650902704 scopus 로고    scopus 로고
    • Mechanisms of allergen-specific immunotherapy
    • Akdis C.A., Akdis M. Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol 2011, 127:18-27.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 18-27
    • Akdis, C.A.1    Akdis, M.2
  • 19
    • 0031784380 scopus 로고    scopus 로고
    • Immunologic changes associated with allergen immunotherapy
    • Durham S.R., Till S.J. Immunologic changes associated with allergen immunotherapy. J Allergy Clin Immunol 1998, 102:157-164.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 157-164
    • Durham, S.R.1    Till, S.J.2
  • 21
    • 0041735323 scopus 로고    scopus 로고
    • Induction of 'blocking' IgG antibodies during immunotherapy
    • Wachholz P.A., Durham S.R. Induction of 'blocking' IgG antibodies during immunotherapy. Clin Exp Allergy 2003, 33:1171-1174.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1171-1174
    • Wachholz, P.A.1    Durham, S.R.2
  • 22
    • 0033197966 scopus 로고    scopus 로고
    • Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum-IgE-facilitated allergen presentation
    • van Neerven R.J., Wikborg T., Lund G., et al. Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum-IgE-facilitated allergen presentation. J Immunol 1999, 163:2944-2952.
    • (1999) J Immunol , vol.163 , pp. 2944-2952
    • van Neerven, R.J.1    Wikborg, T.2    Lund, G.3
  • 23
    • 34548693921 scopus 로고    scopus 로고
    • Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation
    • Razafindratsita A., Saint-Lu N., Mascarell L., et al. Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation. J Allergy Clin Immunol 2007, 120:278-285.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 278-285
    • Razafindratsita, A.1    Saint-Lu, N.2    Mascarell, L.3
  • 24
    • 16444365595 scopus 로고    scopus 로고
    • Impact of sublingual immunotherapy on specific antibody levels in asthmatic children allergic to house dust mites
    • Bahceciler N.N., Arikan C., Taylor A., et al. Impact of sublingual immunotherapy on specific antibody levels in asthmatic children allergic to house dust mites. Int Arch Allergy Immunol 2005, 136:287-294.
    • (2005) Int Arch Allergy Immunol , vol.136 , pp. 287-294
    • Bahceciler, N.N.1    Arikan, C.2    Taylor, A.3
  • 25
    • 0032707795 scopus 로고    scopus 로고
    • Grass pollen immunotherapy decreases the number of mast cells in the skin
    • Durham S.R., Varney V.A., Gaga M., et al. Grass pollen immunotherapy decreases the number of mast cells in the skin. Clin Exp Allergy 1999, 29:1490-1496.
    • (1999) Clin Exp Allergy , vol.29 , pp. 1490-1496
    • Durham, S.R.1    Varney, V.A.2    Gaga, M.3
  • 26
    • 0030003889 scopus 로고    scopus 로고
    • Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma
    • Durham S.R., Ying S., Varney V.A., et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-gamma. J Allergy Clin Immunol 1996, 97:1356-1365.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1356-1365
    • Durham, S.R.1    Ying, S.2    Varney, V.A.3
  • 27
    • 33644907744 scopus 로고    scopus 로고
    • Immune mechanisms of allergen-specific sublingual immunotherapy
    • Moingeon P., Batard T., Fadel R., et al. Immune mechanisms of allergen-specific sublingual immunotherapy. Allergy 2006, 61:151-165.
    • (2006) Allergy , vol.61 , pp. 151-165
    • Moingeon, P.1    Batard, T.2    Fadel, R.3
  • 29
    • 9844266243 scopus 로고    scopus 로고
    • Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen
    • Ebner C., Siemann U., Bohle B., et al. Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phl p 1, a major grass pollen allergen. Clin Exp Allergy 1997, 27:1007-1015.
    • (1997) Clin Exp Allergy , vol.27 , pp. 1007-1015
    • Ebner, C.1    Siemann, U.2    Bohle, B.3
  • 30
    • 0038363534 scopus 로고    scopus 로고
    • IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
    • Jutel M., Akdis M., Budak F., et al. IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol 2003, 33:1205-1214.
    • (2003) Eur J Immunol , vol.33 , pp. 1205-1214
    • Jutel, M.1    Akdis, M.2    Budak, F.3
  • 31
    • 0037504093 scopus 로고    scopus 로고
    • Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy
    • Francis J.N., Till S.J., Durham S.R. Induction of IL-10+CD4+CD25+ T cells by grass pollen immunotherapy. J Allergy Clin Immunol 2003, 111:1255-1261.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1255-1261
    • Francis, J.N.1    Till, S.J.2    Durham, S.R.3
  • 32
    • 22544467453 scopus 로고    scopus 로고
    • Induction of interleukin 10 by sublingual immunotherapy for house dust mites: a preliminary report
    • Ciprandi G., Fenoglio D., Cirillo I., et al. Induction of interleukin 10 by sublingual immunotherapy for house dust mites: a preliminary report. Ann Allergy Asthma Immunol 2005, 95:38-44.
    • (2005) Ann Allergy Asthma Immunol , vol.95 , pp. 38-44
    • Ciprandi, G.1    Fenoglio, D.2    Cirillo, I.3
  • 33
    • 34548237449 scopus 로고    scopus 로고
    • Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation
    • Bohle B., Kinaciyan T., Gerstmayr M., et al. Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation. J Allergy Clin Immunol 2007, 120:707-713.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 707-713
    • Bohle, B.1    Kinaciyan, T.2    Gerstmayr, M.3
  • 34
    • 72849130777 scopus 로고    scopus 로고
    • House dust mite sublingual immunotherapy. The role for transforming growth factor B and functional regulatory T cells
    • O'Hehir R.E., Gardner L.M., de Leon M.P., et al. House dust mite sublingual immunotherapy. The role for transforming growth factor B and functional regulatory T cells. Am J Respir Crit Care Med 2009, 180:936-947.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 936-947
    • O'Hehir, R.E.1    Gardner, L.M.2    de Leon, M.P.3
  • 35
    • 38949121675 scopus 로고    scopus 로고
    • Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells
    • Allam J.P., Peng W.M., Appel T., et al. Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. J Allergy Clin Immunol 2008, 121:368-374.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 368-374
    • Allam, J.P.1    Peng, W.M.2    Appel, T.3
  • 36
    • 0037661991 scopus 로고    scopus 로고
    • Characterization of dendritic cells from human oral mucosa: a new Langerhans' cell type with high constitutive FcepsilonRI expression
    • Allam J.P., Novak N., Fuchs C., et al. Characterization of dendritic cells from human oral mucosa: a new Langerhans' cell type with high constitutive FcepsilonRI expression. J Allergy Clin Immunol 2003, 112:141-148.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 141-148
    • Allam, J.P.1    Novak, N.2    Fuchs, C.3
  • 37
    • 50649122989 scopus 로고    scopus 로고
    • Oral dendritic cells mediate antigen-specific tolerance by stimulating Th1 and regulatory CD4+ T cells
    • Mascarell L., Lombardi V., Louise A., et al. Oral dendritic cells mediate antigen-specific tolerance by stimulating Th1 and regulatory CD4+ T cells. J Allergy Clin Immunol 2008, 122:603-609.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 603-609
    • Mascarell, L.1    Lombardi, V.2    Louise, A.3
  • 38
    • 36048962961 scopus 로고    scopus 로고
    • How do adjuvants work? Important considerations for new generation adjuvants
    • McKee A.S., Munks M.W., Marrack P. How do adjuvants work? Important considerations for new generation adjuvants. Immunity 2007, 27:687-690.
    • (2007) Immunity , vol.27 , pp. 687-690
    • McKee, A.S.1    Munks, M.W.2    Marrack, P.3
  • 39
    • 77949655424 scopus 로고    scopus 로고
    • Lactic acid bacteria as adjuvants for sublingual allergy vaccines
    • van Overtvelt L., Moussu H., Horiot S., et al. Lactic acid bacteria as adjuvants for sublingual allergy vaccines. Vaccine 2010, 28:2986-2992.
    • (2010) Vaccine , vol.28 , pp. 2986-2992
    • van Overtvelt, L.1    Moussu, H.2    Horiot, S.3
  • 40
    • 0038730917 scopus 로고    scopus 로고
    • Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial
    • Kalliomaki M., Salminen S., Poussa T., et al. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 2003, 361:1869-1871.
    • (2003) Lancet , vol.361 , pp. 1869-1871
    • Kalliomaki, M.1    Salminen, S.2    Poussa, T.3
  • 41
    • 22544476790 scopus 로고    scopus 로고
    • Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids
    • Grangette C., Nutten S., Palumbo E., et al. Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids. Proc Natl Acad Sci U S A 2005, 102:10321-10326.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 10321-10326
    • Grangette, C.1    Nutten, S.2    Palumbo, E.3
  • 42
    • 20444503737 scopus 로고    scopus 로고
    • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin
    • Smits H.H., Engering A., van der Kleij D., et al. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005, 115:1260-1267.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 1260-1267
    • Smits, H.H.1    Engering, A.2    van der Kleij, D.3
  • 43
    • 33646177970 scopus 로고    scopus 로고
    • Clinical effects of probiotics are associated with increased interferon-gamma responses in very young children with atopic dermatitis
    • Prescott S.L., Dunstan J.A., Hale J., et al. Clinical effects of probiotics are associated with increased interferon-gamma responses in very young children with atopic dermatitis. Clin Exp Allergy 2005, 35:1557-1564.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1557-1564
    • Prescott, S.L.1    Dunstan, J.A.2    Hale, J.3
  • 44
    • 72949085517 scopus 로고    scopus 로고
    • Lactic acid bacteria differ in their ability to induce functional regulatory T cells in humans
    • de Roock S., van Elk M., van Dijk M.E., et al. Lactic acid bacteria differ in their ability to induce functional regulatory T cells in humans. Clin Exp Allergy 2010, 40:103-110.
    • (2010) Clin Exp Allergy , vol.40 , pp. 103-110
    • de Roock, S.1    van Elk, M.2    van Dijk, M.E.3
  • 45
    • 0036681632 scopus 로고    scopus 로고
    • Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation
    • Zuany-Amorim C., Manlius C., Trifilieff A., et al. Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation. J Immunol 2002, 169:1492-1499.
    • (2002) J Immunol , vol.169 , pp. 1492-1499
    • Zuany-Amorim, C.1    Manlius, C.2    Trifilieff, A.3
  • 46
    • 1642290976 scopus 로고    scopus 로고
    • Bacillus Calmette-Guérin-induced interleukin-12 did not additionally improve clinical and immunologic parameters in asthmatic children treated with sublingual immunotherapy
    • Arikan C., Bahceciler N.N., Deniz G., et al. Bacillus Calmette-Guérin-induced interleukin-12 did not additionally improve clinical and immunologic parameters in asthmatic children treated with sublingual immunotherapy. Clin Exp Allergy 2004, 34:398-405.
    • (2004) Clin Exp Allergy , vol.34 , pp. 398-405
    • Arikan, C.1    Bahceciler, N.N.2    Deniz, G.3
  • 47
    • 0346751969 scopus 로고    scopus 로고
    • Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages
    • Arkwright P.D., David T.J. Effect of Mycobacterium vaccae on atopic dermatitis in children of different ages. Br J Dermatol 2003, 149:1029-1034.
    • (2003) Br J Dermatol , vol.149 , pp. 1029-1034
    • Arkwright, P.D.1    David, T.J.2
  • 48
    • 0242624726 scopus 로고    scopus 로고
    • Effects of BCG revaccination on asthma
    • Choi I.S., Koh Y.I. Effects of BCG revaccination on asthma. Allergy 2003, 58:1114-1116.
    • (2003) Allergy , vol.58 , pp. 1114-1116
    • Choi, I.S.1    Koh, Y.I.2
  • 49
    • 12144287976 scopus 로고    scopus 로고
    • The effect of BCG vaccine at birth on the development of atopy or allergic disease in young children
    • Townley R.G., Barlan I.B., Patino C., et al. The effect of BCG vaccine at birth on the development of atopy or allergic disease in young children. Ann Allergy Asthma Immunol 2004, 92:350-355.
    • (2004) Ann Allergy Asthma Immunol , vol.92 , pp. 350-355
    • Townley, R.G.1    Barlan, I.B.2    Patino, C.3
  • 50
    • 0042074304 scopus 로고    scopus 로고
    • Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features
    • Smit J.J., Van Loveren H., Hoekstra M.O., et al. Mycobacterium vaccae administration during allergen sensitization or challenge suppresses asthmatic features. Clin Exp Allergy 2003, 33:1083-1089.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1083-1089
    • Smit, J.J.1    Van Loveren, H.2    Hoekstra, M.O.3
  • 51
    • 0035094643 scopus 로고    scopus 로고
    • Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease
    • Arkwright P.D., David T.J. Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease. J Allergy Clin Immunol 2001, 107:531-534.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 531-534
    • Arkwright, P.D.1    David, T.J.2
  • 52
  • 53
    • 0035925592 scopus 로고    scopus 로고
    • Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants
    • Pizza M., Giuliani M.M., Fontana M.R., et al. Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants. Vaccine 2001, 19:2534-2541.
    • (2001) Vaccine , vol.19 , pp. 2534-2541
    • Pizza, M.1    Giuliani, M.M.2    Fontana, M.R.3
  • 54
    • 0242303573 scopus 로고    scopus 로고
    • Inhibition of T helper 2-type responses, IgE production and eosinophilia by synthetic lipopeptides
    • Akdis C.A., Kussebi F., Pulendran B., et al. Inhibition of T helper 2-type responses, IgE production and eosinophilia by synthetic lipopeptides. Eur J Immunol 2003, 33:2717-2726.
    • (2003) Eur J Immunol , vol.33 , pp. 2717-2726
    • Akdis, C.A.1    Kussebi, F.2    Pulendran, B.3
  • 55
    • 27744488946 scopus 로고    scopus 로고
    • Vaccinations with T-helper type 1 directing adjuvants have different suppressive effects on the development of allergen-induced T-helper type 2 responses
    • Trujillo-Vargas C.M., Mayer K.D., Bickert T., et al. Vaccinations with T-helper type 1 directing adjuvants have different suppressive effects on the development of allergen-induced T-helper type 2 responses. Clin Exp Allergy 2005, 35:1003-1013.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1003-1013
    • Trujillo-Vargas, C.M.1    Mayer, K.D.2    Bickert, T.3
  • 56
    • 0036126748 scopus 로고    scopus 로고
    • Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma
    • Santeliz J.V., Van Nest G., Traquina P., et al. Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma. J Allergy Clin Immunol 2002, 109:455-462.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 455-462
    • Santeliz, J.V.1    Van Nest, G.2    Traquina, P.3
  • 57
    • 33646190155 scopus 로고    scopus 로고
    • Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy
    • Johansen P., Senti G., Martinez Gomez J.M., et al. Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin Exp Allergy 2005, 35:1591-1598.
    • (2005) Clin Exp Allergy , vol.35 , pp. 1591-1598
    • Johansen, P.1    Senti, G.2    Martinez Gomez, J.M.3
  • 58
    • 20444393509 scopus 로고    scopus 로고
    • TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells
    • Patel M., Xu D., Kewin P., et al. TLR2 agonist ameliorates established allergic airway inflammation by promoting Th1 response and not via regulatory T cells. J Immunol 2005, 174:7558-7563.
    • (2005) J Immunol , vol.174 , pp. 7558-7563
    • Patel, M.1    Xu, D.2    Kewin, P.3
  • 59
    • 33846213140 scopus 로고    scopus 로고
    • Toll-like receptor ligands as novel pharmaceuticals for allergic disorders
    • Goldman M. Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin Exp Immunol 2007, 147:208-216.
    • (2007) Clin Exp Immunol , vol.147 , pp. 208-216
    • Goldman, M.1
  • 60
    • 50649120499 scopus 로고    scopus 로고
    • The TLR2 agonist Pam3CSK4 enhances the induction of antigen-specific tolerance via the sublingual route
    • Lombardi V., van Overtvelt L., Horiot S., et al. The TLR2 agonist Pam3CSK4 enhances the induction of antigen-specific tolerance via the sublingual route. Clin Exp Allergy 2008, 38:1819-1829.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1819-1829
    • Lombardi, V.1    van Overtvelt, L.2    Horiot, S.3
  • 61
    • 36749060150 scopus 로고    scopus 로고
    • A synthetic triacylated pseudo-dipeptide molecule promotes Th1/TReg immune responses and enhances tolerance induction via the sublingual route
    • Mascarell L., Van Overtvelt L., Lombardi L., et al. A synthetic triacylated pseudo-dipeptide molecule promotes Th1/TReg immune responses and enhances tolerance induction via the sublingual route. Vaccine 2007, 26:108-118.
    • (2007) Vaccine , vol.26 , pp. 108-118
    • Mascarell, L.1    Van Overtvelt, L.2    Lombardi, L.3
  • 62
    • 0034012994 scopus 로고    scopus 로고
    • Monophosphoryl lipid A enhances mucosal and systemic immunity to vaccine antigens following intranasal administration
    • Baldridge J.R., Yorgensen Y., Ward J.R., et al. Monophosphoryl lipid A enhances mucosal and systemic immunity to vaccine antigens following intranasal administration. Vaccine 2000, 18:2416-2425.
    • (2000) Vaccine , vol.18 , pp. 2416-2425
    • Baldridge, J.R.1    Yorgensen, Y.2    Ward, J.R.3
  • 63
    • 4143062435 scopus 로고    scopus 로고
    • Resiquimod, a new immune response modifier from the family of imidazoquinolinamines, inhibits allergen-induced Th2 responses, airway inflammation and airway hyper-reactivity in mice
    • Quarcoo D., Weixler S., Joachim R.A., et al. Resiquimod, a new immune response modifier from the family of imidazoquinolinamines, inhibits allergen-induced Th2 responses, airway inflammation and airway hyper-reactivity in mice. Clin Exp Allergy 2004, 34:1314-1320.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1314-1320
    • Quarcoo, D.1    Weixler, S.2    Joachim, R.A.3
  • 64
    • 0034995781 scopus 로고    scopus 로고
    • A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections
    • Drachenberg K.J., Wheeler A.W., Stuebner P., et al. A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections. Allergy 2001, 56:498-505.
    • (2001) Allergy , vol.56 , pp. 498-505
    • Drachenberg, K.J.1    Wheeler, A.W.2    Stuebner, P.3
  • 65
    • 0043264799 scopus 로고    scopus 로고
    • Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies
    • Mothes N., Heinzkill M., Drachenberg K.J., et al. Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies. Clin Exp Allergy 2003, 33:1198-1208.
    • (2003) Clin Exp Allergy , vol.33 , pp. 1198-1208
    • Mothes, N.1    Heinzkill, M.2    Drachenberg, K.J.3
  • 66
    • 33749436870 scopus 로고    scopus 로고
    • Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis
    • Creticos P.S., Schroeder J.T., Hamilton R.G., et al. Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med 2006, 355:1445-1455.
    • (2006) N Engl J Med , vol.355 , pp. 1445-1455
    • Creticos, P.S.1    Schroeder, J.T.2    Hamilton, R.G.3
  • 67
    • 77958150039 scopus 로고    scopus 로고
    • Sublingual allergen-specific immunotherapy adjuvanted with monophosphoryl lipid A: a phase I/IIa study
    • Pfaar O., Barth C., Jaschke C., et al. Sublingual allergen-specific immunotherapy adjuvanted with monophosphoryl lipid A: a phase I/IIa study. Int Arch Allergy Immunol 2010, 154:336-344.
    • (2010) Int Arch Allergy Immunol , vol.154 , pp. 336-344
    • Pfaar, O.1    Barth, C.2    Jaschke, C.3
  • 68
    • 59549090029 scopus 로고    scopus 로고
    • Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy increases CD4+CD25+ T cells in the nasal mucosa of subjects with allergic rhinitis
    • Asai K., Foley S.C., Sumi Y., et al. Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy increases CD4+CD25+ T cells in the nasal mucosa of subjects with allergic rhinitis. Allergol Int 2008, 57:377-381.
    • (2008) Allergol Int , vol.57 , pp. 377-381
    • Asai, K.1    Foley, S.C.2    Sumi, Y.3
  • 69
    • 45949104817 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGFβ
    • Taher Y.A., van Esch B.C., Hofman G.A., et al. 1alpha,25-dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGFβ. J Immunol 2008, 180:5211-5221.
    • (2008) J Immunol , vol.180 , pp. 5211-5221
    • Taher, Y.A.1    van Esch, B.C.2    Hofman, G.A.3
  • 70
    • 72449141678 scopus 로고    scopus 로고
    • The effect of oral steroids with and without vitamin D3 on early efficacy of immunotherapy in asthmatic children
    • Majak P., Rychlik B., Stelmach I. The effect of oral steroids with and without vitamin D3 on early efficacy of immunotherapy in asthmatic children. Clin Exp Allergy 2009, 39:1830-1841.
    • (2009) Clin Exp Allergy , vol.39 , pp. 1830-1841
    • Majak, P.1    Rychlik, B.2    Stelmach, I.3
  • 71
    • 36749096949 scopus 로고    scopus 로고
    • IL-10 inducing adjuvants enhance sublingual immunotherapy efficacy
    • van Overtvelt L., Lombardi V., Horiot S., et al. IL-10 inducing adjuvants enhance sublingual immunotherapy efficacy. Int Arch Allergy Immunol 2008, 145:152-162.
    • (2008) Int Arch Allergy Immunol , vol.145 , pp. 152-162
    • van Overtvelt, L.1    Lombardi, V.2    Horiot, S.3
  • 72
    • 0032776071 scopus 로고    scopus 로고
    • Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3
    • de Jong E.C., Vieira P.L., Kalinski P., et al. Corticosteroids inhibit the production of inflammatory mediators in immature monocyte-derived DC and induce the development of tolerogenic DC3. J Leukoc Biol 1999, 66:201-204.
    • (1999) J Leukoc Biol , vol.66 , pp. 201-204
    • de Jong, E.C.1    Vieira, P.L.2    Kalinski, P.3
  • 73
    • 0034161714 scopus 로고    scopus 로고
    • 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
    • Penna G., Adorini L. 1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000, 164:2405-2411.
    • (2000) J Immunol , vol.164 , pp. 2405-2411
    • Penna, G.1    Adorini, L.2
  • 74
    • 0033152003 scopus 로고    scopus 로고
    • Glucocorticoids affect human dendritic cell differentiation and maturation
    • Piemonti L., Monti P., Allavena P., et al. Glucocorticoids affect human dendritic cell differentiation and maturation. J Immunol 1999, 162:6473-6481.
    • (1999) J Immunol , vol.162 , pp. 6473-6481
    • Piemonti, L.1    Monti, P.2    Allavena, P.3
  • 75
    • 0030802018 scopus 로고    scopus 로고
    • Glucocorticoids and immune function: unknown dimensions and new frontiers
    • Wilckens T., De R.R. Glucocorticoids and immune function: unknown dimensions and new frontiers. Immunol Today 1997, 18:418-424.
    • (1997) Immunol Today , vol.18 , pp. 418-424
    • Wilckens, T.1    De, R.R.2
  • 76
    • 4344696812 scopus 로고    scopus 로고
    • + T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism
    • + T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism. J Allergy Clin Immunol 2004, 114:296-301.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 296-301
    • Dao Nguyen, X.1    Robinson, D.S.2
  • 77
    • 4444304990 scopus 로고    scopus 로고
    • Intranasal immunisation of mice with liposomes containing recombinant meningococcal OpaB and OpaJ proteins
    • de Jonge M.I., Hamstra H.J., Jiskoot W., et al. Intranasal immunisation of mice with liposomes containing recombinant meningococcal OpaB and OpaJ proteins. Vaccine 2004, 22:4021-4028.
    • (2004) Vaccine , vol.22 , pp. 4021-4028
    • de Jonge, M.I.1    Hamstra, H.J.2    Jiskoot, W.3
  • 78
    • 70350769178 scopus 로고    scopus 로고
    • Modular antigen-translocation as a novel vaccine strategy for allergen-specific immunotherapy
    • Crameri R., Kündig T.M., Akdis C.A. Modular antigen-translocation as a novel vaccine strategy for allergen-specific immunotherapy. Curr Opin Allergy Clin Immunol 2009, 9:568-573.
    • (2009) Curr Opin Allergy Clin Immunol , vol.9 , pp. 568-573
    • Crameri, R.1    Kündig, T.M.2    Akdis, C.A.3
  • 79
    • 0032915280 scopus 로고    scopus 로고
    • Safety and efficacy studies of liposomes in specific immunotherapy
    • Galvain S., André C., Vatrinet C., et al. Safety and efficacy studies of liposomes in specific immunotherapy. Curr Ther Res 1999, 60:278-294.
    • (1999) Curr Ther Res , vol.60 , pp. 278-294
    • Galvain, S.1    André, C.2    Vatrinet, C.3
  • 81
    • 0035940308 scopus 로고    scopus 로고
    • Immunostimulating complexes (ISCOMs) for nasal vaccination
    • Hu K.F., Lovgren-Bengtsson K., Morein B. Immunostimulating complexes (ISCOMs) for nasal vaccination. Adv Drug Deliv Rev 2001, 51:149-159.
    • (2001) Adv Drug Deliv Rev , vol.51 , pp. 149-159
    • Hu, K.F.1    Lovgren-Bengtsson, K.2    Morein, B.3
  • 82
    • 33746349797 scopus 로고    scopus 로고
    • Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy
    • Kim N., Kwon S.S., Lee J., et al. Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy. Clin Mol Allergy 2006, 4:1-9.
    • (2006) Clin Mol Allergy , vol.4 , pp. 1-9
    • Kim, N.1    Kwon, S.S.2    Lee, J.3
  • 83
    • 12144290577 scopus 로고    scopus 로고
    • Allergen-loaded biodegradable poly(d,l-lactic-co-glycolic) acid nanoparticles down-regulate an ongoing Th2 response in the BALB/c mouse model
    • Schöll I., Weissenböck A., Förster-Waldl E., et al. Allergen-loaded biodegradable poly(d,l-lactic-co-glycolic) acid nanoparticles down-regulate an ongoing Th2 response in the BALB/c mouse model. Clin Exp Allergy 2004, 34:315-321.
    • (2004) Clin Exp Allergy , vol.34 , pp. 315-321
    • Schöll, I.1    Weissenböck, A.2    Förster-Waldl, E.3
  • 84
    • 4944260149 scopus 로고    scopus 로고
    • Modulation of allergic responses in mice by using biodegradable poly(lactide-co-glycolide) microspheres
    • Jilek S., Walter E., Merkle H.P., et al. Modulation of allergic responses in mice by using biodegradable poly(lactide-co-glycolide) microspheres. J Allergy Clin Immunol 2004, 114:943-950.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 943-950
    • Jilek, S.1    Walter, E.2    Merkle, H.P.3
  • 85
    • 76349083910 scopus 로고    scopus 로고
    • A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1
    • Edlmayr J., Niespodziana K., Linhart B., et al. A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1. J Immunol 2009, 182:6298-6306.
    • (2009) J Immunol , vol.182 , pp. 6298-6306
    • Edlmayr, J.1    Niespodziana, K.2    Linhart, B.3
  • 86
    • 69549130776 scopus 로고    scopus 로고
    • Displaying Fel d 1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy
    • Schmitz N., Dietmeier K., Bauer M., et al. Displaying Fel d 1 on virus-like particles prevents reactogenicity despite greatly enhanced immunogenicity: a novel therapy for cat allergy. J Exp Med 2009, 206:1941-1955.
    • (2009) J Exp Med , vol.206 , pp. 1941-1955
    • Schmitz, N.1    Dietmeier, K.2    Bauer, M.3
  • 87
    • 33646949257 scopus 로고    scopus 로고
    • Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults
    • Kündig T.M., Senti G., Schnetzler G., et al. Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults. J Allergy Clin Immunol 2006, 117:1470-1476.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 1470-1476
    • Kündig, T.M.1    Senti, G.2    Schnetzler, G.3
  • 88
    • 62449179406 scopus 로고    scopus 로고
    • Use of A-type CpG oligodeoxynucleotides as an adjuvant in allergen-specific immunotherapy in humans: a phase I/IIa clinical trial
    • Senti G., Johansen P., Haug S., et al. Use of A-type CpG oligodeoxynucleotides as an adjuvant in allergen-specific immunotherapy in humans: a phase I/IIa clinical trial. Clin Exp Allergy 2009, 39:562-570.
    • (2009) Clin Exp Allergy , vol.39 , pp. 562-570
    • Senti, G.1    Johansen, P.2    Haug, S.3
  • 89
    • 0038460181 scopus 로고    scopus 로고
    • Virus-like particles: a new family of delivery systems
    • Boisgerault F., Moron G., Leclerc C. Virus-like particles: a new family of delivery systems. Expert Rev Vaccines 2002, 1:101-109.
    • (2002) Expert Rev Vaccines , vol.1 , pp. 101-109
    • Boisgerault, F.1    Moron, G.2    Leclerc, C.3
  • 90
    • 66749106297 scopus 로고    scopus 로고
    • Targeting the allergen to oral dendritic cells with mucoadhesive chitosan particles enhances tolerance induction
    • Saint-Lu N., Tourdot S., Razafindrasita A., et al. Targeting the allergen to oral dendritic cells with mucoadhesive chitosan particles enhances tolerance induction. Allergy 2009, 64:1003-1013.
    • (2009) Allergy , vol.64 , pp. 1003-1013
    • Saint-Lu, N.1    Tourdot, S.2    Razafindrasita, A.3
  • 91
    • 68549101513 scopus 로고    scopus 로고
    • A novel nanoparticulate adjuvant for immunotherapy with Lolium perenne
    • Gómez S., Gamazo C., San Roman B., et al. A novel nanoparticulate adjuvant for immunotherapy with Lolium perenne. J Immunol Methods 2009, 348:1-8.
    • (2009) J Immunol Methods , vol.348 , pp. 1-8
    • Gómez, S.1    Gamazo, C.2    San Roman, B.3
  • 92
    • 77954760985 scopus 로고    scopus 로고
    • Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: implications for specific immunotherapy
    • Broos S., Lundberg K., Akagi T., et al. Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: implications for specific immunotherapy. Vaccine 2010, 28:5075-5085.
    • (2010) Vaccine , vol.28 , pp. 5075-5085
    • Broos, S.1    Lundberg, K.2    Akagi, T.3
  • 93
    • 33646507044 scopus 로고    scopus 로고
    • New therapeutic strategies: a chimeric human-cat fusion protein inhibits allergic reactivity
    • Terada T. New therapeutic strategies: a chimeric human-cat fusion protein inhibits allergic reactivity. Clin Exp Allergy 2006, 6:96-100.
    • (2006) Clin Exp Allergy , vol.6 , pp. 96-100
    • Terada, T.1
  • 94
    • 59849090766 scopus 로고    scopus 로고
    • Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity
    • Gerstmayr M., Ilk N., Jahn-Schmid B., et al. Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity. Int Arch Allergy Immunol 2009, 149:231-238.
    • (2009) Int Arch Allergy Immunol , vol.149 , pp. 231-238
    • Gerstmayr, M.1    Ilk, N.2    Jahn-Schmid, B.3
  • 95
    • 5944236044 scopus 로고    scopus 로고
    • OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway
    • Jeannin P., Renno T., Goetsch L., et al. OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway. Nat Immunol 2000, 1:502-509.
    • (2000) Nat Immunol , vol.1 , pp. 502-509
    • Jeannin, P.1    Renno, T.2    Goetsch, L.3
  • 96
    • 0034818555 scopus 로고    scopus 로고
    • Targeting of nasal mucosa-associated antigen-presenting cells in vivo with an outer membrane protein A derived from Klebsiella pneumoniae
    • Goetsch L., Gonzalez A., Plotnicky-Gilquin H., et al. Targeting of nasal mucosa-associated antigen-presenting cells in vivo with an outer membrane protein A derived from Klebsiella pneumoniae. Infect Immun 2001, 69:6434-6444.
    • (2001) Infect Immun , vol.69 , pp. 6434-6444
    • Goetsch, L.1    Gonzalez, A.2    Plotnicky-Gilquin, H.3
  • 97
    • 10744222365 scopus 로고    scopus 로고
    • The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization
    • Haicheur N., Benchetrit F., Amessou M., et al. The B subunit of Shiga toxin coupled to full-size antigenic protein elicits humoral and cell-mediated immune responses associated with a Th1-dominant polarization. Int Immunol 2003, 15:1161-1171.
    • (2003) Int Immunol , vol.15 , pp. 1161-1171
    • Haicheur, N.1    Benchetrit, F.2    Amessou, M.3
  • 98
    • 0036891032 scopus 로고    scopus 로고
    • The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells
    • El Azami El Idrissi M., Ladant D., Leclerc C. The adenylate cyclase of Bordetella pertussis: a vector to target antigen presenting cells. Toxicon 2002, 40:1661-1665.
    • (2002) Toxicon , vol.40 , pp. 1661-1665
    • El Azami El Idrissi, M.1    Ladant, D.2    Leclerc, C.3
  • 99
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination
    • Bonifaz L.C., Bonnyay D.P., Charalambous A., et al. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med 2004, 199:815-824.
    • (2004) J Exp Med , vol.199 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3
  • 100
    • 0141737488 scopus 로고    scopus 로고
    • Mucosal immunization with DNA vaccines
    • Hobson P., Barnfield C., Barnes A., et al. Mucosal immunization with DNA vaccines. Methods 2003, 31:217-224.
    • (2003) Methods , vol.31 , pp. 217-224
    • Hobson, P.1    Barnfield, C.2    Barnes, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.