Exogenous surfactant protects against endotoxin induced acute respiratory distress syndrome in rodents via vascular endothelial growth factor

Pathology Research and Practice

Volumn 207, Issue 5, 2011, Pages 279-284

  Mittal, Neha ^a   Sanyal, Sankar Nath ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

ARDS; BrdU; PCNA; Surfactant; VEGF

Indexed keywords

ARTIFICIAL LUNG SURFACTANT; CYCLINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; LUNG SURFACTANT; VASCULOTROPIN;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; LUNG ALVEOLUS; LUNG CAPILLARY; LUNG ENDOTHELIUM; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT;

EID: 79955393028     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2011.01.010     Document Type: Article

References (36)

1. Ware L.B., Matthay M.A. The acute respiratory distress syndrome. N. Engl. J. Med. 2000, 342:1334-1349.
2. Pittet J.F., Mackersie R.C., Martin T.R., Matthay M.A. Biological markers of acute lung injury: prognostic and pathogenetic significance. Am. J. Respir. Crit. Care Med. 1997, 155:1187-1205.
3. Ferrara N., Gerber H.P., LeCouter J. The biology of VEGF and its receptors. Nat. Med. 2003, 9:669-676.
4. Kaner R.J., Crystal R.G. Compartmentalization of vascular endothelial growth factor to the epithelial surface of the human lung. Mol. Med. 2001, 7:240-246.
5. Boussat S., Eddahibi S., Coste A., Fataccioli V., Gouge M., Housset B., Adnot S., Maitre B. Expression and regulation of vascular endothelial growth factor in human pulmonary epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 2000, 279:L371-L378.
6. Zachary I., Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc. Res. 2001, 49:568-581.
7. Kaner R.J., Ladetto J.V., Singh R., Fukuda N., Matthay M.A., Crystal R.G. Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. Am. J. Respir. Cell Mol. Biol. 2000, 22:657-664.
8. Thickett D.R., Armstrong L., Christie S.J., Millar A.B. Vascular endothelial growth factor may contribute to increased vascular permeability in acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 2001, 164:1601-1605.
9. Compernolle V., Brusselmans K., Acker T., Hoet P., Tjwa M., Beck H., Plaisance S., Dor Y., Keshet E., Lupu F., Nemery B., Dewerchin M., van Veldhoven P., Carmeliet P., Plate K. Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med. 2002, 7:702-710.
10. Thickett D.R., Armstrong L., Millar A.B. A role for vascular endothelial growth factor in acute and resolving lung injury. Am. J. Respir. Crit. Care Med. 2002, 166:1332-1337.
11. Abadie Y., Bregeon F., Papazian L., Lange F., Chailley-Heu B., Thomas P., Duvaldestin P., Adnot S., Maitre B., Delclaux C. Decreased VEGF concentration in lung tissue and vascular injury during ARDS. Eur. Respir. J. 2005, 25:139-146.
12. Fehrenbach H. Alveolar epithelial type II cell: defender of the alveolus revisited. Respir. Res. 2001, 2:33-46.
13. Aliotta J.M., Passero M., Meharg J., Klinger J., Dooner M., Pimentel J., Quesenberry P.J. Stem cells and pulmonary metamorphosis: new concepts in repair and regeneration. J. Cell. Physiol. 2005, 204:725-741.
14. Mittal N., Sanyal S.N. Exogenous surfactant suppresses inflammation in experimental endotoxin-induced lung injury. J. Environ. Toxicol. Pathol. Oncol. 2009, 28:341-349.
15. Mittal N., Sanyal S.N. Cyclooxygenase inhibition enhances the effects of surfactant therapy in endotoxin induced rat model of ARDS. Inflammation 2010, 10.1007/s10753-010-9211-6.
16. Mittal N., Sanyal S.N. Intratracheal instillation of surfactant inhibits lipopolysaccharide induced acute respiratory distress syndrome in rats. Am. J. Biomed. Sci. 2010, 2:190-201.
17. Mittal N., Sanyal S.N. Immunomodulatory properties of exogenous surfactant in adult rat alveolar macrophages. Immunopharmacol. Immunol. 2010, 32:153-159.
18. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
19. Johnson D.G., Walker C.L. Cyclins and cell cycle checkpoints. Annu. Rev. Pharmacol. Toxicol. 1999, 39:295-312.
20. Paunesku T., Mittal S., Protic M., Oryhon J., Korolev S.V., Joachimiak A., Woloschak G.E. Proliferating cell nuclear antigen (PCNA): ringmaster of the genome. Int. J. Radiat. Biol. 2001, 77:1007-1021.
21. Ma Q.Y., Williamson K.E., Rowlands B.J. Variability of cell proliferation in the proximal and distal colon of normal rats and rats with dimethylhydrazine induced carcinogenesis. World J. Gastroenterol. 2002, 8:847-852.
22. Koyama S., Sato E., Haniuda M., Numanami H., Nagai S., Izumi T. Decreased level of vascular endothelial growth factor in bronchoalveolar lavage fluid of normal smokers and patients with pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 2002, 166:382-385.
23. Bhatt A.J., Pryhuber G.S., Huyck H., Watkins R.H., Metlay L.A., Maniscalco W.M. Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia. Am. J. Respir. Crit. Care Med. 2001, 164:1971-1980.
24. Maitre B., Boussat S., Jean D., Gouge M., Brochard L., Housset B., Adnot S., Delclaux C. Vascular endothelial growth factor synthesis in the acute phase of experimental and clinical lung injury. Eur. Respir. J. 2001, 18:100-106.
25. Fehrenbach A., Pufe T., Wittwer T., Nagib R., Dreyer N., Pech T., Petersen W., Fehrenbach H., Wahlers T., Richter J. Reduced vascular endothelial growth factor correlates with alveolar epithelial damage after experimental ischemia and reperfusion. J. Heart Lung Transplant. 2003, 22:967-978.
26. Monacci W., Merrill M., Olfield E. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues. Am. J. Physiol. 1993, 264:C995-C1002.
27. Tsokos M., Pufe T., Paulsen F., Anders S., Mentlein R. Pulmonary expression of vascular endothelial growth factor in sepsis. Arch. Pathol. Lab. Med. 2003, 127:331-335.
28. Meduri G.U., Kohler G., Headley S., Tolley E., Stentz F., Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest 1995, 108:1303-1314.
29. Suter P.M., Suter S., Girardin E., Roux-Lombard P., Grau G.E., Dayer J.M. High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsis. Am. Rev. Respir. Dis. 1992, 145:1016-1022.
30. Yoshida S., Ono M., Shono T., Izumi H., Ishibashi T., Suzuki H., Kuwano M. Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol. Cell. Biol. 1997, 17:4015-4023.
31. Klekamp J.G., Jarzecka K., Perkett E.A. Exposure to hyperoxia decreases the expression of vascular endothelial growth factor and its receptors in adult rat lungs. Am. J. Pathol. 1999, 154:823-832.
32. Tang K., Rossiter H.B., Wagner P.D., Breen E.C. Lung-targeted VEGF inactivation lead to an emphysema phenotype in mice. J. Appl. Physiol. 2004, 97:1559-1566.
33. Bardales R.H., Xie S.S., Schaefer R.F., Hsu S.M. Apoptosis is a major pathway responsible for the resolution of type II pneumocytes in acute lung injury. Am. J. Pathol. 1996, 149:845-852.
34. Albertine K.H., Soulier M.F., Wang Z., Ishizaka A., Hashimoto S., Zimmerman G.A., Matthay M.A., Ware L.B. Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am. J. Pathol. 2002, 161:1783-1796.
35. Haimovitz-Friedman A., Cordon-Cardo C., Bayoumy S., Garzotto M., McLoughlin M., Gallily R., Edwards C.K., Schuchman E.H., Fuks Z., Kolesnick R. Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. J. Exp. Med. 1997, 186:1831-1841.
36. Corne J., Chupp G., Lee C.G., Homer R.J., Zhu Z., Chen Q., Ma B., Du Y., Roux F., McArdle J., Waxman A.B., Elias J.A. IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. J. Clin. Invest. 2000, 106:783-791.