Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (aβ42) oligomers along pathway different from fibril formation

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Kumar, Amit ^a   Bullard, Rebekah L ^a   Patel, Pritesh ^a   Paslay, Lea C ^b   Singh, Dipti ^b   Bienkiewicz, Ewa A ^c   Morgan, Sarah E ^b   Rangachari, Vijayaraghavan ^a  

^a University of Southern Mississippi   (United States)

^b University of Southern Mississippi   (United States)

^c FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; DECANOIC ACID; FATTY ACID; LAURIC ACID; LONG CHAIN FATTY ACID; MEDIUM CHAIN FATTY ACID; NONANOIC ACID; OLIGOMER; SATURATED FATTY ACID; AMYLOID BETA PROTEIN; GUANIDINE; THIAZOLE DERIVATIVE; THIOFLAVINE;

ARTICLE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; GLYCOPROTEIN SYNTHESIS; IN VITRO STUDY; MOLECULAR WEIGHT; PROTEIN AGGREGATION; PROTEIN ISOLATION; PROTEIN LIPID INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; THERMODYNAMICS; THERMOSTABILITY; BIOLOGICAL MODEL; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECT; FLUORESCENCE; ISOLATION AND PURIFICATION; METABOLISM; MICELLE; PROTEIN DENATURATION; PROTEIN QUATERNARY STRUCTURE; WESTERN BLOTTING;

AMYLOID BETA-PEPTIDES; BLOTTING, WESTERN; CIRCULAR DICHROISM; FATTY ACIDS, NONESTERIFIED; FLUORESCENCE; GUANIDINE; MICELLES; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; PROTEIN DENATURATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS; THIAZOLES;

EID: 79955382682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018759     Document Type: Article

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