Short communication: Assessing antihypertensive activity in native and model Queso Fresco cheeses1

Journal of Dairy Science

Volumn 94, Issue 5, 2011, Pages 2280-2284

  Paul, M ^a   Van Hekken, D L ^a  

^a EASTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

Angiotensin converting enzyme inhibition; Antihypertensive activity; Bioactive peptide; Hispanic cheese

Indexed keywords

ANTIHYPERTENSIVE AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MILK PROTEIN;

ANIMAL; ARTICLE; CHEESE; FOOD HANDLING; FUNCTIONAL FOOD; ISOLATION AND PURIFICATION; MEXICO; TIME; UNITED STATES;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; CHEESE; FOOD HANDLING; FUNCTIONAL FOOD; MEXICO; MILK PROTEINS; TIME FACTORS; UNITED STATES;

EID: 79955124606     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2010-3852     Document Type: Article

References (20)

1. Chen Z.Y., Peng C., Jiao R., Wong Y.M., Yang N., Huang Y. Anti-hypertensive nutraceuticals and functional foods. J. Agric. Food Chem. 2009, 57:4485-4499.
2. Gomez-Ruiz J.A., Ramos M., Recio I. Angiotensin-converting enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures. Int. Dairy J. 2002, 12:697-706.
3. Gomez-Ruiz J.A., Taborda G., Amigo L., Recio I., Ramos M. Identification of ACE-inhibitory peptides in different Spanish cheeses by tandem mass spectrometry. Eur. Food Res. Technol. 2006, 223:595-601.
4. Hou W.C., Chen H.J., Lin Y.H. Antioxidant peptides with angiotensin converting enzyme inhibitory activities and applications for angiotensin converting enzyme purification. J. Agric. Food Chem. 2003, 51:1706-1709.
5. Korhonen H., Pihlanto A. Bioactive peptides: Production and functionality. Int. Dairy J. 2006, 16:945-960.
6. Lignitto L., Cavatorta V., Balzan S., Gabai G., Galaverna G., Novelli E., Sforza S., Segato S. Angiotensin-converting enzyme inhibitory activity of water-soluble extracts of Asiago d'allevo cheese. Int. Dairy J. 2010, 20:11-17.
7. Lopez-Fandino R., Otte J., van Camp J. Physiological, chemical and technological aspects of milk-protein-derived peptides with antihypertensive and ACE-inhibitory activity. Int. Dairy J. 2006, 16:1277-1293.
8. Meyer J., Butikofer U., Walther B., Wechsler D., Sieber R. Hot topic: Changes in angiotensin-converting enzyme inhibition and concentrations of the tripeptides Val-Pro-Pro and Ile-Pro-Pro during ripening of different Swiss cheese varieties. J. Dairy Sci. 2009, 92:826-836.
9. Mizuno S., Nishimura S., Matsuura K., Gotou T., Yamamoto N. Release of short and proline-rich antihypertensive peptides from casein hydrolysate with an Aspergillus oryzae protease. J. Dairy Sci. 2004, 87:3183-3188.
10. Nakamura Y., Yamamoto N., Sakai K., Okubo A., Yamazaki S., Takano T. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J. Dairy Sci. 1995, 78:777-783.
11. Nakamura Y., Yamamoto N., Sakai K., Takano T. Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. J. Dairy Sci. 1995, 78:1253-1257.
12. Pihlanto A., Virtanen T., Korhonen H. Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effect of fermented milk. Int. Dairy J. 2010, 20:3-10.
13. Renye J.A., Somkuti G.A., Vallejo-Cordoba B., Van Hekken D.L., Gonzalez-Cordova A.F. Characterization of the microflora isolted from queso fresco made from raw and pasteurized milk. J. Food Saf. 2008, 28:59-75.
14. Ryhanen E.L., Pihlanto-Leppala A., Pahkala E. A new type of ripened, low-fat cheese with bioactive properties. Int. Dairy J. 2001, 11:441-447.
15. Saito T., Nakamura T., Kitazawa H., Kawai Y., Itoh T. Isolation and structural analysis of antihypertensive peptides that exist naturally in Gouda cheese. J. Dairy Sci. 2000, 83:1434-1440.
16. Silva S.V., Pihlanto A., Malcata F.X. Bioactive peptides in ovine and caprine cheeselike systems prepared with proteases from Cynara cardunculus. J. Dairy Sci. 2006, 89:3336-3344.
17. Singh T.K., Fox P.F., Healy A. Isolation and identification of further peptides in the diafiltration retentate of the water-soluble fraction of Cheddar cheese. J. Dairy Res. 1997, 64:433-443.
18. van der Ven C., Gruppen H., de Bont D.B.A., Voragen A.G.J. Optimization of the angiotensin converting enzyme inhibition by why protein hydrolysates using response surface methodology. Int. Dairy J. 2002, 12:813-820.
19. Van Hekken D.L., Tunick M.H., Park Y.W. Rheological and proteolytic properties of Monterey Jack goat's milk cheese during aging. J. Agric. Food Chem. 2004, 52:5372-5377.
20. Vermeirssen V., Van Camp J., Verstraete W. Optimisation and validation of an angiotensin-converting enzyme inhibition assay for the screening of bioactive peptides. J. Biochem. Biophys. Methods 2002, 51:75-87.