Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice

Metabolic Brain Disease

Volumn 26, Issue 1, 2011, Pages 9-19

  McCarty, Douglas M ^a   Dirosario, Julianne ^a   Gulaid, Kadra ^a   Killedar, Smruti ^a   Oosterhof, Arie ^b   Van Kuppevelt, Toin H ^b   Martin, Paul T ^a   Fu, Haiyan ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Glycobiosynthesis; Heparan sulfate; Lysosomal storage disease; MPS IIIB; Neuropathology

Indexed keywords

ANTIBODY; AO4B08 ANTIBODY; EPIMERASE; EPITOPE; EV3C3 ANTIBODY; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; HS4C3 ANTIBODY; HS4E4 ANTIBODY; RB4EA12 ANTIBODY; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BRAIN CORTEX; BRAIN STEM; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LYSOSOME; MOUSE; NERVE CELL; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PURKINJE CELL; SANFILIPPO SYNDROME; SANFILIPPO SYNDROME TYPE B; THALAMUS; TISSUE DISTRIBUTION; WHITE MATTER;

ANIMALS; BRAIN; CARBOHYDRATE EPIMERASES; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTORS; HEPARITIN SULFATE; LYSOSOMES; MICE; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSIS III; NEURONS; PROTEIN ISOFORMS; SULFOTRANSFERASES; TISSUE DISTRIBUTION;

MUS;

EID: 79955084773     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-010-9230-x     Document Type: Article

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