Moderate exercise training provides left ventricular tolerance to acute pressure overload

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 300, Issue 3, 2011, Pages

  Moreira Gonçalves, Daniel ^a,b   Henriques Coelho, Tiago ^a   Fonseca, Hélder ^b   Ferreira, Rita Maria ^c   Amado, Francisco ^c   Leite Moreira, Adelino ^a   Duarte, José Alberto ^b  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Cardiac overload; Cardioprotection; Endurance training; Oxidative damage

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DESCENDING AORTA; DIASTOLE; EXERCISE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE OVERLOAD; HEART LEFT VENTRICLE PRESSURE; HEART PROTECTION; HEMODYNAMIC MONITORING; MALE; MANOMETER; NONHUMAN; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; RAT; SEDENTARY LIFESTYLE; SYSTOLE; SYSTOLIC BLOOD PRESSURE;

ANIMALS; CASPASE 3; HEMODYNAMICS; MALE; PHYSICAL CONDITIONING, ANIMAL; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; SEDENTARY LIFESTYLE; VENTRICULAR FUNCTION, LEFT;

EID: 79955061640     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01008.2010     Document Type: Article

References (49)

1. Ascensao A, Magalhaes J, Soares JMC, Ferreira R, Neuparth MJ, Marques F, Oliveira PJ, Duarte JA. Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis. Am J Physiol Heart Circ Physiol 289: H722-H731, 2005.
2. Billingham ME, Mason JW, Bristow MR, Daniels JR. Anthracycline cardiomyopathy monitored by morphologic changes. Cancer Treat Rep 62: 865-872, 1978.
3. Boissiere J, Eder V, Machet MC, Courteix D, Bonnet P. Moderate exercise training does not worsen left ventricle remodeling and function in untreated severe hypertensive rats. J Appl Physiol 104: 321-327, 2008.
4. Chen CY, Hsu HC, Lee BC, Lin HJ, Chen YH, Huang HC, Ho YL, Chen MF. Exercise training improves cardiac function in infarcted rabbits: involvement of autophagic function and fatty acid utilization. Eur J Heart Fail 12: 323-330, 2010.
5. Choksi KB, Boylston WH, Rabek JP, Widger WR, Papaconstantinou J. Oxidatively damaged proteins of heart mitochondrial electron transport complexes. Biochim Biophys Acta 1688: 95-101, 2004.
6. Choksi KB, Papaconstantinou J. Age-related alterations in oxidatively damaged proteins of mouse heart mitochondrial electron transport chain complexes. Free Radic Biol Med 44: 1795-1805, 2008.
7. Demirel HA, Powers SK, Zergeroglu MA, Shanely RA, Hamilton K, Coombes J, Naito H. Short-term exercise improves myocardial tolerance to in vivo ischemia-reperfusion in the rat. J Appl Physiol 91: 2205-2212, 2001.
8. de Tombe PP, Belus A, Piroddi N, Scellini B, Walker JS, Martin AF, Tesi C, Poggesi C. Myofilament calcium sensitivity does not affect cross-bridge activation-relaxation kinetics. Am J Physiol Regul Integr Comp Physiol 292: R1129-R1136, 2007.
9. Emter CA, McCune SA, Sparagna GC, Radin MJ, Moore RL. Lowintensity exercise training delays onset of decompensated heart failure in spontaneously hypertensive heart failure rats. Am J Physiol Heart Circ Physiol 289: H2030-H2038, 2005.
10. Falcao-Pires I, Goncalves N, Henriques-Coelho T, Moreira-Goncalves D, Roncon-Albuquerque R Jr, Leite-Moreira AF. Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol 296: H2007-H2014, 2009.
11. Freimann S, Scheinowitz M, Yekutieli D, Feinberg MS, Eldar M, Kessler-Icekson G. Prior exercise training improves the outcome of acute myocardial infarction in the rat: Heart structure, function, and gene expression. J Am Coll Cardiol 45: 931-938, 2005.
12. French JP, Hamilton KL, Quindry JC, Lee Y, Upchurch PA, Powers SK. Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain. FASEB J 22: 2862-2871, 2008.
13. French JP, Quindry JC, Falk DJ, Staib JL, Lee Y, Wang KKW, Powers SK. Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition. Am J Physiol Heart Circ Physiol 290: H128-H136, 2006.
14. Frey N, Katus HA, Olson EN, Hill JA. Hypertrophy of the heart: a new therapeutic target? Circulation 109: 1580-1589, 2004.
15. Garciarena CD, Pinilla OA, Nolly MB, Laguens RP, Escudero EM, Cingolani HE, Ennis IL. Endurance training in the spontaneously hypertensive rat: conversion of pathological into physiological cardiac hypertrophy. Hypertension 53: 708-714, 2009.
16. Guerra MS, Roncon-Albuquerque R Jr, Lourenco AP, Falcao-Pires I, Cibrao-Coutinho P, Leite-Moreira AF. Remote myocardium gene expression after 30 and 120 min of ischaemia in the rat. Exp Physiol 91: 473-480, 2006.
17. Hikoso S, Ikeda Y, Yamaguchi O, Takeda T, Higuchi Y, Hirotani S, Kashiwase K, Yamada M, Asahi M, Matsumura Y, Nishida K, Matsuzaki M, Hori M, Otsu K. Progression of heart failure was suppressed by inhibition of apoptosis signal-regulating kinase 1 via transcoronary gene transfer. J Am Coll Cardiol 50: 453-462, 2007.
18. Huang CC, Lin TJ, Chen CC, Lin WT. Endurance training accelerates exhaustive exercise-induced mitochondrial DNA deletion and apoptosis of left ventricle myocardium in rats. Eur J Appl Physiol 107: 697-706, 2009.
19. Kavazis AN, McClung JM, Hood DA, Powers SK. Exercise induces a cardiac mitochondrial phenotype that resists apoptotic stimuli. Am J Physiol Heart Circ Physiol 294: H928-H935, 2008.
20. Kawano S, Kubota T, Monden Y, Tsutsumi T, Inoue T, Kawamura N, Tsutsui H, Sunagawa K. Blockade of NF-κB improves cardiac function and survival after myocardial infarction. Am J Physiol Heart Circ Physiol 291: H1337-H1344, 2006.
21. Kolwicz SC, MacDonnell SM, Renna BF, Reger PO, Seqqat R, Rafiq K, Kendrick ZV, Houser SR, Sabri A, Libonati JR. Left ventricular remodeling with exercise in hypertension. Am J Physiol Heart Circ Physiol 297: H1361-H1368, 2009.
22. Konhilas JP, Watson PA, Maass A, Boucek DM, Horn T, Stauffer BL, Luckey SW, Rosenberg P, Leinwand LA. Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res 98: 540-548, 2006.
23. Lachance D, Plante E, Bouchard-Thomassin AA, Champetier S, Roussel E, Drolet MC, Arsenault M, Couet J. Moderate exercise training improves survival and ventricular remodeling in an animal model of left ventricular volume overload. Circ Heart Fail 2: 437-445, 2009.
24. Lawler JM, Powers SK, Hammeren J, Martin AD. Oxygen cost of treadmill running in 24-month-old Fischer-344 rats. Med Sci Sports Exer 25: 1259-1264, 1993.
25. Leite-Moreira A, Gillebert T. Nonuniform course of left ventricular pressure fall and its regulation by load and contractile state. Circulation 90: 2481-2491, 1994.
26. Leite-Moreira AF. Current perspectives in diastolic dysfunction and diastolic heart failure. Heart 92: 712-718, 2006.
27. Leite-Moreira AF, Castro-Chaves P, Pimentel-Nunes P, Lima-Carneiro A, Guerra MS, Soares JB, Ferreira-Martins J. Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect. Br J Pharmacol 147: 690-697, 2006.
28. Leite-Moreira AF, Correia-Pinto J, Gillebert TC. Afterload induced changes in myocardial relaxation: a mechanism for diastolic dysfunction. Cardiovasc Res 43: 344-353, 1999.
29. Lin G, Brownsey R, MacLeod K. Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. Cell Mol Life Sci 66: 919-932, 2009.
30. Liu B, Tewari AK, Zhang LW, Green-Church KB, Zweier JL, Chen YR, He GL. Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target. Bba-Proteins Proteom 1794: 476-485, 2009.
31. Lu N, Zhang Y, Li H, Gao Z. Oxidative and nitrative modifications of alpha-enolase in cardiac proteins from diabetic rats. Free Radic Biol Med 48: 873-881, 2010.
32. Marks AR. Physiological systems under pressure. J Clin Invest 118: 411-412, 2008.
33. Matasova LV, Popova TN. Aconitate hydratase of mammals under oxidative stress. Biochemistry (Mosc) 73: 957-964, 2008.
34. McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 338: 171-179, 1998.
35. Medeiros A, Rolim NPL, Oliveira RSF, Rosa KT, Mattos KC, Casarini DE, Irigoyen MC, Krieger EM, Krieger JE, Negrao CE, Brum PC. Exercise training delays cardiac dysfunction and prevents calcium handling abnormalities in sympathetic hyperactivity-induced heart failure mice. J Appl Physiol 104: 103-109, 2008.
36. Miyamoto MI, del Monte F, Schmidt U, DiSalvo TS, Kang ZB, Matsui T, Guerrero JL, Gwathmey JK, Rosenzweig A, Hajjar RJ. Adenoviral gene transfer of SERCA2a improves left-ventricular function in aorticbanded rats in transition to heart failure. Proc Natl Acad Sci USA 97: 793-798, 2000.
37. Morisco C, Sadoshima J, Trimarco B, Arora R, Vatner DE, Vatner SF. Is treating cardiac hypertrophy salutary or detrimental: the two faces of Janus. Am J Physiol Heart Circ Physiol 284: H1043-H1047, 2003.
38. Onai Y, Suzuki Ji Maejima Y, Haraguchi G, Muto S, Itai A, Isobe M. Inhibition of NF-αB improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. Am J Physiol Heart Circ Physiol 292: H530-H538, 2007.
39. Perrino C, Prasad SVN, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. J Clin Invest 116: 1547-1560, 2006.
40. Quindry JC, Schreiber L, McGinnis G, Nanayakkara G, Amin R. Autophagy and exercise cardioprotection: the role of mitochondrial and sarcolemmal KATP channels. Med Sci Sports Exer 42: 40, 2010.
41. 2+ handling protein expression in heart failure. Physiol Genomics 29: 246-252, 2007.
42. Roncon-Albuquerque R Jr, Vasconcelos M, Lourenco AP, Brandao-Nogueira A, Teles A, Henriques-Coelho T, Leite-Moreira AF. Acute changes of biventricular gene expression in volume and right ventricular pressure overload. Life Sci 78: 2633-2642, 2006.
43. Tardiff JC. Cardiac hypertrophy: stressing out the heart. J Clin Invest 116: 1467-1470, 2006.
44. Teiger E, Than VD, Richard L, Wisnewsky C, Tea BS, Gaboury L, Tremblay J, Schwartz K, Hamet P. Apoptosis in pressure overloadinduced heart hypertrophy in the rat. J Clin Invest 97: 2891-2897, 1996.
45. Timmers L, van Keulen JK, Hoefer IE, Meijs MFL, van Middelaar B, den Ouden K, van Echteld CJA, Pasterkamp G, de Kleijn DPV. Targeted deletion of nuclear factor κB p50 enhances cardiac remodeling and dysfunction following myocardial infarction. Circ Res 104: 699-706, 2009.
46. van der Velden J. Functional significance of myofilament protein oxidation. Eur Heart J 27: 764-765, 2006.
47. van Empel VP, Bertrand AT, van Oort RJ, van der Nagel R, Engelen M, van Rijen HV, Doevendans PA, Crijns HJ, Ackerman SL, Sluiter W, De Windt LJ. EUK-8, a superoxide dismutase and catalase mimetic, reduces cardiac oxidative stress and ameliorates pressure overload-induced heart failure in the harlequin mouse mutant. J Am Coll Cardiol 48: 824-832, 2006.
48. Varian KD, Raman S, Janssen PML. Measurement of myofilament calcium sensitivity at physiological temperature in intact cardiac trabeculae. Am J Physiol Heart Circ Physiol 290: H2092-H2097, 2006.
49. Yamaguchi O, Higuchi Y, Hirotani S, Kashiwase K, Nakayama H, Hikoso S, Takeda T, Watanabe T, Asahi M, Taniike M, Matsumura Y, Tsujimoto I, Hongo K, Kusakari Y, Kurihara S, Nishida K, Ichijo H, Hori M, Otsu K. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc Natl Acad Sci USA 100: 15883-15888, 2003.