메뉴 건너뛰기




Volumn 300, Issue 3, 2011, Pages

Exercise training normalizes impaired NOS-dependent responses of cerebral arterioles in type 1 diabetic rats

Author keywords

Adenosine 5' diphosphate; Endothelial nitric oxide synthase; N methyl D aspartate; Neuronal nitric oxide synthase; Nitroglycerin; Pial arterioles; Superoxide; Western blot

Indexed keywords

ADENOSINE DIPHOSPHATE; BRAIN PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCERYL TRINITRATE; N METHYL DEXTRO ASPARTIC ACID; NEURONAL NITRIC OXIDE SYNTHASE; SUPEROXIDE;

EID: 79955060676     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00873.2010     Document Type: Article
Times cited : (32)

References (73)
  • 1
    • 0034530525 scopus 로고    scopus 로고
    • NOC/oFQ PKC-dependent superoxide generation contributes to hypoxic-ischemic impairment of NMDA cerebrovasodilation
    • Armstead WM. NOC/oFQ PKC-dependent superoxide generation contributes to hypoxic-ischemic impairment of NMDA cerebrovasodilation. Am J Physiol Heart Circ Physiol 279: H2678-H2684, 2000.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Armstead, W.M.1
  • 2
    • 36849078036 scopus 로고    scopus 로고
    • Acute infusion of nicotine impairs nNOSdependent reactivity of cerebral arterioles via an increase in oxidative stress
    • Arrick DM, Mayhan WG. Acute infusion of nicotine impairs nNOSdependent reactivity of cerebral arterioles via an increase in oxidative stress. J Appl Physiol 103: 2062-2067, 2007.
    • (2007) J Appl Physiol , vol.103 , pp. 2062-2067
    • Arrick, D.M.1    Mayhan, W.G.2
  • 3
    • 36348930541 scopus 로고    scopus 로고
    • nNOS-dependent reactivity of cerebral arterioles in Type 1 diabetes
    • Arrick DM, Sharpe GM, Sun H, Mayhan WG. nNOS-dependent reactivity of cerebral arterioles in Type 1 diabetes. Brain Res 1184: 365-371, 2007.
    • (2007) Brain Res , vol.1184 , pp. 365-371
    • Arrick, D.M.1    Sharpe, G.M.2    Sun, H.3    Mayhan, W.G.4
  • 4
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 61: 661-666, 2004.
    • (2004) Arch Neurol , vol.61 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 6
    • 0027104465 scopus 로고
    • Involvement of nitric oxide in endothelium-dependent, phasic relaxation caused by histamine in monkey cerebral arteries
    • Ayajiki K, Okamura T, Toda N. Involvement of nitric oxide in endothelium-dependent, phasic relaxation caused by histamine in monkey cerebral arteries. Jpn J Pharmacol 60: 357-362, 1992.
    • (1992) Jpn J Pharmacol , vol.60 , pp. 357-362
    • Ayajiki, K.1    Okamura, T.2    Toda, N.3
  • 8
    • 37849052672 scopus 로고    scopus 로고
    • Systemic and mitochondrial adaptive responses to moderate exercise in rodents
    • Boveris A, Navarro A. Systemic and mitochondrial adaptive responses to moderate exercise in rodents. Free Radic Biol Med 44: 224-229, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 224-229
    • Boveris, A.1    Navarro, A.2
  • 9
    • 1842785177 scopus 로고    scopus 로고
    • Cerebral dysfunction in type 1 diabetes: Effects of insulin, vascular risk factors and blood-glucose levels
    • Brands AM, Kessels RP, de Haan EH, Kappelle LJ, Biessels GJ. Cerebral dysfunction in type 1 diabetes: effects of insulin, vascular risk factors and blood-glucose levels. Eur J Pharmacol 490: 159-168, 2004.
    • (2004) Eur J Pharmacol , vol.490 , pp. 159-168
    • Brands, A.M.1    Kessels, R.P.2    de Haan, E.H.3    Kappelle, L.J.4    Biessels, G.J.5
  • 10
    • 0025933592 scopus 로고
    • Hyperpolarization and relaxation of resistance arteries in response to adenosine diphosphate
    • Brayden JE. Hyperpolarization and relaxation of resistance arteries in response to adenosine diphosphate. Circ Res 69: 1415-1420, 1991.
    • (1991) Circ Res , vol.69 , pp. 1415-1420
    • Brayden, J.E.1
  • 11
    • 0032964529 scopus 로고    scopus 로고
    • Daily exercise enhances acetylcholineinduced dilation in mesenteric and hindlimb vasculature of hypertensive rats
    • Chen Y, Collins HL, DiCarlo SE. Daily exercise enhances acetylcholineinduced dilation in mesenteric and hindlimb vasculature of hypertensive rats. Clin Exp Hypertens 21: 353-376, 1999.
    • (1999) Clin Exp Hypertens , vol.21 , pp. 353-376
    • Chen, Y.1    Collins, H.L.2    di Carlo, S.E.3
  • 13
    • 0036081660 scopus 로고    scopus 로고
    • Effects of NADH and NADPH on superoxide levels and cerebral vascular tone
    • Didion SP, Faraci FM. Effects of NADH and NADPH on superoxide levels and cerebral vascular tone. Am J Physiol Heart Circ Physiol 282: H688-H695, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Didion, S.P.1    Faraci, F.M.2
  • 14
    • 0034791448 scopus 로고    scopus 로고
    • Superoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD
    • Didion SP, Hathaway CA, Faraci FM. Superoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD. Am J Physiol Heart Circ Physiol 281: H1697-H1703, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Didion, S.P.1    Hathaway, C.A.2    Faraci, F.M.3
  • 15
    • 0023118941 scopus 로고
    • Regional cerebral blood flow decreases during chronic and acute hyperglycemia
    • Duckrow RB, Beard DC, Brennan RW. Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke 18: 52-58, 1987.
    • (1987) Stroke , vol.18 , pp. 52-58
    • Duckrow, R.B.1    Beard, D.C.2    Brennan, R.W.3
  • 16
    • 0037304737 scopus 로고    scopus 로고
    • Impairment of nitric oxide synthasedependent dilatation of cerebral arterioles during infusion of nicotine
    • Fang Q, Sun H, Mayhan WG. Impairment of nitric oxide synthasedependent dilatation of cerebral arterioles during infusion of nicotine. Am J Physiol Heart Circ Physiol 284: H528-H534, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Fang, Q.1    Sun, H.2    Mayhan, W.G.3
  • 17
    • 0025944055 scopus 로고
    • Role of endothelium-derived relaxing factor in cerebral circulation: Large arteries vs. microcirculation
    • Faraci FM. Role of endothelium-derived relaxing factor in cerebral circulation: large arteries vs. microcirculation. Am J Physiol Heart Circ Physiol 261: H1038-H1042, 1991.
    • (1991) Am J Physiol Heart Circ Physiol , vol.261
    • Faraci, F.M.1
  • 18
    • 0027514356 scopus 로고
    • Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain
    • Faraci FM, Breese KR. Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain. Circ Res 72: 476-480, 1993.
    • (1993) Circ Res , vol.72 , pp. 476-480
    • Faraci, F.M.1    Breese, K.R.2
  • 19
    • 0028128219 scopus 로고
    • Responses of cerebral arterioles to kainate
    • Faraci FM, Breese KR, Heistad DD. Responses of cerebral arterioles to kainate. Stroke 25: 2080-2084, 1994.
    • (1994) Stroke , vol.25 , pp. 2080-2084
    • Faraci, F.M.1    Breese, K.R.2    Heistad, D.D.3
  • 20
    • 0028808287 scopus 로고
    • 7-Nitroindazole inhibits brain nitric oxide synthase and cerebral vasodilatation in response to N-methyl-D-aspartate
    • Faraci FM, Brian JE. 7-Nitroindazole inhibits brain nitric oxide synthase and cerebral vasodilatation in response to N-methyl-D-aspartate. Stroke 26: 2172-2176, 1995.
    • (1995) Stroke , vol.26 , pp. 2172-2176
    • Faraci, F.M.1    Brian, J.E.2
  • 21
    • 0027477810 scopus 로고
    • Role of ATP-sensitive potassium channels in the basilar artery
    • Faraci FM, Heistad DD. Role of ATP-sensitive potassium channels in the basilar artery. Am J Physiol Heart Circ Physiol 264: H8-H13, 1993.
    • (1993) Am J Physiol Heart Circ Physiol , vol.264
    • Faraci, F.M.1    Heistad, D.D.2
  • 22
    • 0031738772 scopus 로고    scopus 로고
    • Effects of intense exercise training on endothelium-dependent exercise-induced vasodilatation
    • Franke WD, Stephens GM, Schmid PG. Effects of intense exercise training on endothelium-dependent exercise-induced vasodilatation. Clin Physiol 18: 521-528, 1998.
    • (1998) Clin Physiol , vol.18 , pp. 521-528
    • Franke, W.D.1    Stephens, G.M.2    Schmid, P.G.3
  • 24
    • 0034201168 scopus 로고    scopus 로고
    • Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training
    • Fukai T, Siegfried MR, Ushio-Fukai M, Cheng Y, Kojda G, Harrison DG. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest 105: 1631-1639, 2000.
    • (2000) J Clin Invest , vol.105 , pp. 1631-1639
    • Fukai, T.1    Siegfried, M.R.2    Ushio-Fukai, M.3    Cheng, Y.4    Kojda, G.5    Harrison, D.G.6
  • 25
    • 73449098615 scopus 로고    scopus 로고
    • Increased neuronal nitric oxide synthase activity in retinal neurons in early diabetic retinopathy
    • Giove TJ, Deshpande MM, Gagen CS, Eldred WD. Increased neuronal nitric oxide synthase activity in retinal neurons in early diabetic retinopathy. Mol Vis 15: 2249-2258, 2009.
    • (2009) Mol Vis , vol.15 , pp. 2249-2258
    • Giove, T.J.1    Deshpande, M.M.2    Gagen, C.S.3    Eldred, W.D.4
  • 26
    • 2442689237 scopus 로고    scopus 로고
    • Exercise training improves aortic endotheliumdependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats
    • Graham DA, Rush JW. Exercise training improves aortic endotheliumdependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats. J Appl Physiol 96: 2088-2096, 2004.
    • (2004) J Appl Physiol , vol.96 , pp. 2088-2096
    • Graham, D.A.1    Rush, J.W.2
  • 27
    • 9244228465 scopus 로고    scopus 로고
    • Effect of exercise training on endothelium-derived nitric oxide function in humans
    • Green DJ, Maiorana A, O'Driscoll G, Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561: 1-25, 2004.
    • (2004) J Physiol , vol.561 , pp. 1-25
    • Green, D.J.1    Maiorana, A.2    O'Driscoll, G.3    Taylor, R.4
  • 28
    • 0035909016 scopus 로고    scopus 로고
    • Endothelium-mediated relaxation of porcine collateral-dependent arterioles is improved by exercise training
    • Griffin KL, Woodman CR, Price EM, Laughlin MH, Parker JL. Endothelium-mediated relaxation of porcine collateral-dependent arterioles is improved by exercise training. Circulation 104: 1393-1398, 2001.
    • (2001) Circulation , vol.104 , pp. 1393-1398
    • Griffin, K.L.1    Woodman, C.R.2    Price, E.M.3    Laughlin, M.H.4    Parker, J.L.5
  • 29
    • 0038755650 scopus 로고    scopus 로고
    • Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase
    • Hambrecht R, Adams V, Erbs S, Linke A, Krankel N, Shu Y, Baither Y, Gielen S, Thiele H, Gummert JF, Mohr FW, Schuler G. Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107: 3152-3158, 2003.
    • (2003) Circulation , vol.107 , pp. 3152-3158
    • Hambrecht, R.1    Adams, V.2    Erbs, S.3    Linke, A.4    Krankel, N.5    Shu, Y.6    Baither, Y.7    Gielen, S.8    Thiele, H.9    Gummert, J.F.10    Mohr, F.W.11    Schuler, G.12
  • 30
    • 0032534496 scopus 로고    scopus 로고
    • Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure
    • Hambrecht R, Fiehn E, Weigl C, Gielen S, Hamann C, Kaiser R, Yu J, Adams V, Niebauer J, Schuler G. Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 98: 2709-2715, 1998.
    • (1998) Circulation , vol.98 , pp. 2709-2715
    • Hambrecht, R.1    Fiehn, E.2    Weigl, C.3    Gielen, S.4    Hamann, C.5    Kaiser, R.6    Yu, J.7    Adams, V.8    Niebauer, J.9    Schuler, G.10
  • 31
    • 53949126138 scopus 로고    scopus 로고
    • Increased nitric oxide synthase activity and Hsp90 association in skeletal muscle following chronic exercise
    • Harris MB, Mitchell BM, Sood SG, Webb RC, Venema RC. Increased nitric oxide synthase activity and Hsp90 association in skeletal muscle following chronic exercise. Eur J Appl Physiol 104: 795-802, 2008.
    • (2008) Eur J Appl Physiol , vol.104 , pp. 795-802
    • Harris, M.B.1    Mitchell, B.M.2    Sood, S.G.3    Webb, R.C.4    Venema, R.C.5
  • 32
    • 1842471294 scopus 로고    scopus 로고
    • Exercise and endothelial function: Role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients
    • Higashi Y, Yoshizumi M. Exercise and endothelial function: role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients. Pharmacol Ther 102: 87-96, 2004.
    • (2004) Pharmacol Ther , vol.102 , pp. 87-96
    • Higashi, Y.1    Yoshizumi, M.2
  • 33
    • 0033554460 scopus 로고    scopus 로고
    • Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects. Role of endothelium-derived nitric oxide
    • Higashi Y, Sasaki S, Kurisu S, Yoshimizu A, Sasaki N, Matsuura H, Kajiyama G, Oshima T. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects. Role of endothelium-derived nitric oxide. Circulation 100: 1194-1202, 1999.
    • (1999) Circulation , vol.100 , pp. 1194-1202
    • Higashi, Y.1    Sasaki, S.2    Kurisu, S.3    Yoshimizu, A.4    Sasaki, N.5    Matsuura, H.6    Kajiyama, G.7    Oshima, T.8
  • 35
    • 0036893288 scopus 로고    scopus 로고
    • Antioxidant enzyme expression in health and disease: Effects of exercise and hypertension
    • Johnson P. Antioxidant enzyme expression in health and disease: effects of exercise and hypertension. Comp Biochem Physiol C Toxicol Pharmacol 133: 493-505, 2002.
    • (2002) Comp Biochem Physiol C Toxicol Pharmacol , vol.133 , pp. 493-505
    • Johnson, P.1
  • 36
    • 0030926448 scopus 로고    scopus 로고
    • Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure
    • Katz SD, Yuen J, Bijou R, LeJemtel TH. Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol 82: 1488-1492, 1997.
    • (1997) J Appl Physiol , vol.82 , pp. 1488-1492
    • Katz, S.D.1    Yuen, J.2    Bijou, R.3    le Jemtel, T.H.4
  • 37
    • 0028952059 scopus 로고
    • Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles
    • Koller A, Huang A, Sun D, Kaley G. Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles. Circ Res 76: 544-550, 1995.
    • (1995) Circ Res , vol.76 , pp. 544-550
    • Koller, A.1    Huang, A.2    Sun, D.3    Kaley, G.4
  • 38
    • 0032434846 scopus 로고    scopus 로고
    • Enhanced endothelium-dependent vasodilatation in human skin vasculature induced by physical conditioning
    • Kvernmo HD, Stefanovska A, Kirkeboen KA, Osterud B, Kvernebo K. Enhanced endothelium-dependent vasodilatation in human skin vasculature induced by physical conditioning. Eur J Appl Physiol 79: 30-36, 1998.
    • (1998) Eur J Appl Physiol , vol.79 , pp. 30-36
    • Kvernmo, H.D.1    Stefanovska, A.2    Kirkeboen, K.A.3    Osterud, B.4    Kvernebo, K.5
  • 39
  • 40
    • 0031435680 scopus 로고    scopus 로고
    • Effects of exercise-induced oxidative stress on nitric oxide release and antioxidant activity
    • Lawson DL, Chen L, Mehta JL. Effects of exercise-induced oxidative stress on nitric oxide release and antioxidant activity. Am J Cardiol 80: 1640-1642, 1997.
    • (1997) Am J Cardiol , vol.80 , pp. 1640-1642
    • Lawson, D.L.1    Chen, L.2    Mehta, J.L.3
  • 41
    • 0037459810 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats
    • Manschot SM, Biessels GJ, Cameron NE, Cotter MA, Kamal A, Kappelle LJ, Gispen WH. Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. Brain Res 966: 274-282, 2003.
    • (2003) Brain Res , vol.966 , pp. 274-282
    • Manschot, S.M.1    Biessels, G.J.2    Cameron, N.E.3    Cotter, M.A.4    Kamal, A.5    Kappelle, L.J.6    Gispen, W.H.7
  • 43
    • 2342578845 scopus 로고    scopus 로고
    • Influence of exercise on dilatation of the basilar artery during diabetes mellitus
    • Mayhan WG, Sun H, Mayhan JF, Patel KP. Influence of exercise on dilatation of the basilar artery during diabetes mellitus. J Appl Physiol 96: 1730-1737, 2004.
    • (2004) J Appl Physiol , vol.96 , pp. 1730-1737
    • Mayhan, W.G.1    Sun, H.2    Mayhan, J.F.3    Patel, K.P.4
  • 44
    • 0026478732 scopus 로고
    • Endothelium-dependent responses of cerebral arterioles to adenosine 5′-diphosphate
    • Mayhan WG. Endothelium-dependent responses of cerebral arterioles to adenosine 5′-diphosphate. J Vasc Res 29: 353-358, 1992.
    • (1992) J Vasc Res , vol.29 , pp. 353-358
    • Mayhan, W.G.1
  • 45
    • 0344043305 scopus 로고    scopus 로고
    • Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
    • Miller FJ, Gutterman DD, Rios CD, Heistad DD, Davidson BL. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res 82: 1298-1305, 1998.
    • (1998) Circ Res , vol.82 , pp. 1298-1305
    • Miller, F.J.1    Gutterman, D.D.2    Rios, C.D.3    Heistad, D.D.4    Davidson, B.L.5
  • 47
    • 0029118723 scopus 로고
    • Endothelium-dependent vasodilation of proximal coronary arteries from exercise-trained pigs
    • Oltman CL, Parker JL, Laughlin MH. Endothelium-dependent vasodilation of proximal coronary arteries from exercise-trained pigs. J Appl Physiol 79: 33-40, 1995.
    • (1995) J Appl Physiol , vol.79 , pp. 33-40
    • Oltman, C.L.1    Parker, J.L.2    Laughlin, M.H.3
  • 48
    • 77954406979 scopus 로고    scopus 로고
    • The effect of regular exercise on penile nitric oxide synthase expression in rats
    • Ozbek E, Tasci AI, Ilbey YO, Simsek A, Somay A, Metin G. The effect of regular exercise on penile nitric oxide synthase expression in rats. Int J Androl 33: 623-628, 2010.
    • (2010) Int J Androl , vol.33 , pp. 623-628
    • Ozbek, E.1    Tasci, A.I.2    Ilbey, Y.O.3    Simsek, A.4    Somay, A.5    Metin, G.6
  • 49
    • 0025738337 scopus 로고
    • Chronic hyperglycemic diabetes in the rat is associated with a selective impairment of cerebral vasodilatory responses
    • Pelligrino DA, Albrecht RF. Chronic hyperglycemic diabetes in the rat is associated with a selective impairment of cerebral vasodilatory responses. J Cereb Blood Flow Metab 11: 667-677, 1991.
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 667-677
    • Pelligrino, D.A.1    Albrecht, R.F.2
  • 50
    • 0037707816 scopus 로고    scopus 로고
    • Differential role of PTK, ERK and p38 MAPK in superoxide impairment of NMDA cerebrovasodilation
    • Philip S, Armstead WM. Differential role of PTK, ERK and p38 MAPK in superoxide impairment of NMDA cerebrovasodilation. Brain Res 979: 98-103, 2003.
    • (2003) Brain Res , vol.979 , pp. 98-103
    • Philip, S.1    Armstead, W.M.2
  • 51
    • 0344298914 scopus 로고    scopus 로고
    • Exercise training-induced alterations in skeletal muscle antioxidant capacity: A brief review
    • Powers SK, Ji LL, Leeuwenburgh C. Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review. Med Sci Sports Exerc 107: 987-997, 1999.
    • (1999) Med Sci Sports Exerc , vol.107 , pp. 987-997
    • Powers, S.K.1    Ji, L.L.2    Leeuwenburgh, C.3
  • 54
    • 79955053136 scopus 로고    scopus 로고
    • Mechanisms underlying vascular effects of chronic resveratrol in streptozotocin-diabetic rats
    • Roghani M, Baluchnejadmojarad T. Mechanisms underlying vascular effects of chronic resveratrol in streptozotocin-diabetic rats. Phytother Res 10: 1-7, 2009.
    • (2009) Phytother Res , vol.10 , pp. 1-7
    • Roghani, M.1    Baluchnejadmojarad, T.2
  • 55
    • 0037377579 scopus 로고    scopus 로고
    • Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium
    • Rush JW, Turk JR, Laughlin MH. Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium. Am J Physiol Heart Circ Physiol 284: H1378-H1387, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Rush, J.W.1    Turk, J.R.2    Laughlin, M.H.3
  • 57
    • 0043071350 scopus 로고    scopus 로고
    • Cognitive efficiency declines over time in adults with Type 1 diabetes: Effects of micro-and macrovascular complications
    • Ryan CM, Geckle MO, Orchard TJ. Cognitive efficiency declines over time in adults with Type 1 diabetes: effects of micro-and macrovascular complications. Diabetologia 46: 940-948, 2003.
    • (2003) Diabetologia , vol.46 , pp. 940-948
    • Ryan, C.M.1    Geckle, M.O.2    Orchard, T.J.3
  • 58
    • 0031975594 scopus 로고    scopus 로고
    • Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka long-evans Tokushima fatty rat, a model of spontaneous NIDDM
    • Sakamoto S, Minami K, Niwa Y, Ohnaka M, Nakaya Y, Mizuno A, Kuwajima M, Shima K. Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka long-evans Tokushima fatty rat, a model of spontaneous NIDDM. Diabetes 47: 82-86, 1998.
    • (1998) Diabetes , vol.47 , pp. 82-86
    • Sakamoto, S.1    Minami, K.2    Niwa, Y.3    Ohnaka, M.4    Nakaya, Y.5    Mizuno, A.6    Kuwajima, M.7    Shima, K.8
  • 59
    • 0025165484 scopus 로고
    • A comparison of cerebral blood flow during basal, hypotensive, hypoxic and hypercapnic conditions between normal and streptozotocin diabetic rats
    • Simpson RE, Phillis JW, Buchannan J. A comparison of cerebral blood flow during basal, hypotensive, hypoxic and hypercapnic conditions between normal and streptozotocin diabetic rats. Brain Res 531: 136-142, 1990.
    • (1990) Brain Res , vol.531 , pp. 136-142
    • Simpson, R.E.1    Phillis, J.W.2    Buchannan, J.3
  • 60
    • 0036435243 scopus 로고    scopus 로고
    • Enhanced NO-mediated dilations in skeletal muscle arterioles of chronically exercised rats
    • Sun D, Huang A, Koller A, Kaley G. Enhanced NO-mediated dilations in skeletal muscle arterioles of chronically exercised rats. Microvasc Res 64: 491-496, 2002.
    • (2002) Microvasc Res , vol.64 , pp. 491-496
    • Sun, D.1    Huang, A.2    Koller, A.3    Kaley, G.4
  • 61
    • 33644866018 scopus 로고    scopus 로고
    • Role of NAD(P)H oxidase in alcohol-induced impairment of endothelial nitric oxide synthase-dependent dilation of cerebral arterioles
    • Sun H, Zheng H, Molacek E, Fang Q, Patel KP, Mayhan WG. Role of NAD(P)H oxidase in alcohol-induced impairment of endothelial nitric oxide synthase-dependent dilation of cerebral arterioles. Stroke 37: 495-500, 2006.
    • (2006) Stroke , vol.37 , pp. 495-500
    • Sun, H.1    Zheng, H.2    Molacek, E.3    Fang, Q.4    Patel, K.P.5    Mayhan, W.G.6
  • 62
    • 0028322037 scopus 로고
    • Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats
    • Sun D, Huang A, Koller A, Kaley G. Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats. J Appl Physiol 76: 2241-2247, 1994.
    • (1994) J Appl Physiol , vol.76 , pp. 2241-2247
    • Sun, D.1    Huang, A.2    Koller, A.3    Kaley, G.4
  • 63
    • 0036092203 scopus 로고    scopus 로고
    • Impairment of neuronal nitric oxide synthase-dependent dilatation of cerebral arterioles during chronic alcohol consumption
    • Sun H, Patel KP, Mayhan WG. Impairment of neuronal nitric oxide synthase-dependent dilatation of cerebral arterioles during chronic alcohol consumption. Alcohol Clin Exp Res 26: 663-670, 2002.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 663-670
    • Sun, H.1    Patel, K.P.2    Mayhan, W.G.3
  • 67
    • 0033535969 scopus 로고    scopus 로고
    • Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids and oxidant stress
    • Varin R, Mulder P, Richard V, Tamion F, Devaux C, Henry JP, Lallemand F, Lerebours G, Thuillez C. Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids and oxidant stress. Circulation 99: 2951-2957, 1999.
    • (1999) Circulation , vol.99 , pp. 2951-2957
    • Varin, R.1    Mulder, P.2    Richard, V.3    Tamion, F.4    Devaux, C.5    Henry, J.P.6    Lallemand, F.7    Lerebours, G.8    Thuillez, C.9
  • 68
    • 0142186830 scopus 로고    scopus 로고
    • Pain and the blood-brain barrier: Obstacles to drug delivery
    • Wolka AM, Huber JD, Davis TP. Pain and the blood-brain barrier: obstacles to drug delivery. Adv Drug Deliv Rev 55: 987-1006, 2003.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 987-1006
    • Wolka, A.M.1    Huber, J.D.2    Davis, T.P.3
  • 69
    • 15544381276 scopus 로고    scopus 로고
    • Exercise-induced increase in skeletal muscle vasodilatory responses in obese Zucker rats
    • Xiang L, Naik J, Hester RL. Exercise-induced increase in skeletal muscle vasodilatory responses in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol 288: R987-R991, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Xiang, L.1    Naik, J.2    Hester, R.L.3
  • 70
    • 0032587490 scopus 로고    scopus 로고
    • P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats
    • You J, Johnson TD, Marrelli SP, Mombouli JV, Bryan RM. P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats. Stroke 30: 1125-1133, 1999.
    • (1999) Stroke , vol.30 , pp. 1125-1133
    • You, J.1    Johnson, T.D.2    Marrelli, S.P.3    Mombouli, J.V.4    Bryan, R.M.5
  • 71
    • 0034731353 scopus 로고    scopus 로고
    • Insulin restores neuronal nitric oxide synthase expression in streptozotocin-induced diabetic rats
    • Yu WJ, Juang SW, Chin WT, Chi TC, Chang CJ, Cheng JT. Insulin restores neuronal nitric oxide synthase expression in streptozotocin-induced diabetic rats. Life Sci 68: 625-634, 2000.
    • (2000) Life Sci , vol.68 , pp. 625-634
    • Yu, W.J.1    Juang, S.W.2    Chin, W.T.3    Chi, T.C.4    Chang, C.J.5    Cheng, J.T.6
  • 72
    • 0032853801 scopus 로고    scopus 로고
    • Decrease of nitric oxide synthase in the cerebrocortex of streptozotocin-induced diabetic rats
    • Yu WJ, Juang SW, Chin WT, Chi TC, Wu TJ, Cheng JT. Decrease of nitric oxide synthase in the cerebrocortex of streptozotocin-induced diabetic rats. Neurosci Lett 272: 99-102, 1999.
    • (1999) Neurosci Lett , vol.272 , pp. 99-102
    • Yu, W.J.1    Juang, S.W.2    Chin, W.T.3    Chi, T.C.4    Wu, T.J.5    Cheng, J.T.6
  • 73
    • 18044372661 scopus 로고    scopus 로고
    • Exercise training improves endogenous nitric oxide mechanisms within the paraventricular nucleus in rats with heart failure
    • Zheng H, Li YF, Cornish KG, Zucker IH, Patel KP. Exercise training improves endogenous nitric oxide mechanisms within the paraventricular nucleus in rats with heart failure. Am J Physiol Heart Circ Physiol 288: H2332-H2341, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Zheng, H.1    Li, Y.F.2    Cornish, K.G.3    Zucker, I.H.4    Patel, K.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.