nNOS-dependent reactivity of cerebral arterioles in Type 1 diabetes

Brain Research

Volumn 1184, Issue 1, 2007, Pages 365-371

  Arrick, Denise M ^a   Sharpe, Glenda M ^a   Sun, Hong ^a   Mayhan, William G ^a  

^a NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Brain; Diabetes; Kainate; Nitric oxide; NMDA; Superoxide anion

Indexed keywords

CITRATE SODIUM; GLYCERYL TRINITRATE; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; NEURONAL NITRIC OXIDE SYNTHASE; STREPTOZOCIN; SUPEROXIDE; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BRAIN MICROCIRCULATION; CONTROLLED STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; VASODILATATION;

ANIMALS; CEREBRAL ARTERIES; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; KAINIC ACID; MALE; N-METHYLASPARTATE; NITRIC OXIDE SYNTHASE; NITROGLYCERIN; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; SUPEROXIDES;

RATTUS;

EID: 36348930541     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.10.004     Document Type: Article

References (51)

1. Abbott R.D., Donahue R.P., MacMahon S.W., Reed D.M., and Yano K. Diabetes and the risk of stroke. J. Am. Med. Assoc. 257 (1987) 949-952
2. Agullo L., and Garcia A. Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture. Biochem. Biophys. Res. Commun. 182 (1992) 1362-1368
3. Arrick D.M., Sharpe G.M., Sun H., and Mayhan W.G. Diabetes-induced cerebrovascular dysfunction: role of poly(ADP-ribose) polymerase. Microvasc. Res. 73 (2007) 1-6
4. Barrett-Connor E., and Khaw K.T. Diabetes mellitus: an independent risk factor for stroke?. Am. J. Epidemiol. 128 (1988) 116-123
5. Boger R.H., Bode-Boger S.M., Szuba A., Tsao P.S., Chan J.R., Tangphao O., Blaschke T.F., and Cooke J.P. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 98 (1998) 1842-1847
6. Busija D.W., and Leffler C.W. Dilator effects of amino acid neurotransmitters on piglet pial arterioles. Am. J. Physiol. 257 (1989) H1200-H1203
7. Didion S.P., and Faraci F.M. Effects of NADH and NADPH on superoxide levels and cerebral vascular tone. Am. J. Physiol. 282 (2002) H688-H695
8. Didion S.P., and Faraci F.M. Angiotensin II produces superoxide-mediated impairment of endothelial function in cerebral arterioles. Stroke 34 (2003) 2038-2042
9. Didion S.P., Ryan M.J., Didion L.A., Fegan P.E., Sigmund C.D., and Faraci F.M. Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice. Circ. Res. 91 (2002) 938-944
10. Fang Q., Sun H., and Mayhan W.G. Impairment of nitric oxide synthase-dependent dilatation of cerebral arterioles during infusion of nicotine. Am. J. Physiol, Heart Circ. Physiol. 284 (2003) H528-H534
11. Faraci F.M., and Breese K.R. Nitric oxide mediates vasodilatation in response to activation of N-methyl-d-aspartate receptors in brain. Circ. Res. 72 (1993) 476-480
12. Faraci F.M., and Brian J.E. Nitric oxide and the cerebral circulation. Stroke 25 (1994) 692-703
13. Faraci F.M., and Brian J.E. 7-nitroindazole inhibits brain nitric oxide synthase and cerebral vasodilatation in response to N-methyl-d-aspartate. Stroke 26 (1995) 2172-2176
14. Faraci F.M., Breese K.R., and Heistad D.D. Responses of cerebral arterioles to kainate. Stroke 25 (1994) 2080-2084
15. Fergus A., and Lee K.S. Regulation of cerebral microvessels by glutamatergic mechanisms. Brain Res. 754 (1997) 35-45
16. Fujii K., Heistad D.D., and Faraci F.M. Effect of diabetes mellitus on flow-mediated and endothelium-dependent dilatation of the rat basilar artery. Stroke 23 (1992) 1494-1498
17. Garthwaite J., Garthwaite G., Plamer R.M.J., and Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur. J. Pharmacol. 172 (1989) 413-416
18. Garthwaite J., Southam E., and Anderton M. A kainate receptor linked to nitric oxide synthesis from arginine. J. Neurochem. 53 (1989) 1952-1954
19. Kim D.E., Suh Y.S., Lee M.S., Kim K.Y., Lee J.H., Lee H.S., Hong K.W., and Kim C.D. Vascular NAD(P)H oxidase triggers delayed cerebral vasospasm after subarachnoid hemorrhage in rats. Stroke 33 (2002) 2687-2691
20. Kissela B.M., Khoury J., Kleindorfer D., Woo D., Schneider A., Alwell K., Miller R., Ewing I., Moomaw C.J., Szaflarski J.P., Gebel J., Shukla R., and Broderick J.P. Epidemiology of ischemic stroke in patients with diabetes: the greater Cincinnati/Northern Kentucky Stroke Study. Diabetes Care 28 (2005) 355-359
21. Kontos H.A. Oxygen radicals in cerebral vascular injury. Circ. Res. 57 (1985) 508-516
22. Koo J.R., and Vaziri N.D. Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species. Kidney Int. 63 (2003) 195-201
23. Landmesser U., Dikalov S., Price S.R., McCann L., Fukai T., Holland S.M., Mitch W.E., and Harrison D.G. Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J. Clin. Invest. 111 (2003) 1201-1209
24. Landmesser U., Harrison D.G., and Drexler H. Oxidant stress-a major cause of reduced endothelial nitric oxide availability in cardiovascular disease. Eur. J. Clin. Pharmacol. 62 Suppl 13 (2006) 13-19
25. Mayhan W.G. Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus. Am. J. Physiol. 256 (1989) H621-H625
26. Mayhan W.G. Impairment of endothelium-dependent dilatation of the basilar artery during diabetes mellitus. Brain Res. 580 (1992) 297-302
27. Mayhan W.G. Responses of cerebral arterioles to activation of b-adrenergic receptors during diabetes mellitus. Stroke 25 (1994) 141-146
28. Mayhan W.G. Superoxide dismutase partially restores impaired dilatation of the basilar artery during diabetes mellitus. Brain Res. 760 (1997) 204-209
29. Mayhan W.G., and Faraci F.M. Responses of cerebral arterioles in diabetic rats to activation of ATP-sensitive potassium channels. Am. J. Physiol. 265 (1993) H152-H157
30. Mayhan W.G., and Heistad D.D. Permeability of blood-brain barrier to various sized molecules. Am. J. Physiol. 248 (1985) H712-H718
31. Mayhan W.G., Simmons L.K., and Sharpe G.M. Mechanism of impaired responses of cerebral arterioles during diabetes mellitus. Am. J. Physiol. 260 (1991) H319-H326
32. Mayhan W.G., Arrick D.M., Sharpe G.M., Patel K.P., and Sun H. Inhibition of NAD(P)H oxidase alleviates impaired NOS-dependent responses of pial arterioles in Type 1 diabetes mellitus. Microcirculation 13 (2006) 567-575
33. Murphy S., Simmons M.L., Agullo L., Garcia A., Feinstein D.L., Galea E., Reis D.J., Minc-Golomb D., and Schwartz J.P. Synthesis of nitric oxide in CNS glial cells. TINS 16 (1993) 323-328
34. Pelligrino D.A., and Albrecht R.F. Chronic hyperglycemic diabetes in the rat is associated with a selective impairment of cerebral vasodilatory responses. J. Cereb. Blood Flow Metab. 11 (1991) 667-677
35. Pelligrino D.A., Miletich D.J., and Albrecht R.F. Diminished muscarinic receptor-mediated cerebral blood flow response in streptozotocin-treated rats. Am. J. Physiol. 262 (1992) E447-E454
36. Phillips S.A., Drenjancevic-Peric I., Frisbee J.C., and Lombard J.H. Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries. Am. J. Physiol, Heart Circ. Physiol. 287 (2004) H545-H552
37. Phillips S.A., Sylvester F.A., and Frisbee J.C. Oxidant stress and constrictor reactivity impair cerebral artery dilation in obese Zucker rats. Am. J. Physiol., Regul. Integr. Comp. Physiol. 288 (2005) R522-R530
38. Rodella L., Bianchi M., Corsetti G., Rezzani R., and Bianchi R. Neuronal nitric oxide synthase decreases in the peripheral but not the central nervous system of diabetic rats. Neurosci. Res. Commun. 27 (2000) 183-189
39. Rosenblum W.I. Effects of free radical generation on mouse pial arterioles: probable role of hydroxyl radicals. Am. J. Physiol. 245 (1983) H139-H142
40. Sasaki T., Yasuda H., Maeda K., and Kikkawa R. Hyperalgesia and decreased neuronal nitric oxide synthase in diabetes rats. NeuroReport 9 (1998) 243-247
41. Sun H., and Mayhan W.G. Temporal effect of alcohol consumption on reactivity of pial arterioles: role of oxygen radicals. Am. J. Physiol. 280 (2001) H992-H1001
42. Sun H., Patel K.P., and Mayhan W.G. Impairment of neuronal nitric oxide synthase-dependent dilatation of cerebral arterioles during chronic alcohol consumption. Alcohol., Clin. Exp. Res. 26 (2002) 663-670
43. Sun H., Molacek E., Zheng H., Fang Q., Patel K.P., and Mayhan W.G. Alcohol-induced impairment of neuronal nitric oxide synthase (nNOS)-dependent dilation of cerebral arterioles: role of NAD(P)H oxidase. J. Mol. Cell. Cardiol. 40 (2006) 321-328
44. Takeda M., Mori F., Yoshida A., Takamiya A., Nakagomi S., Sato E., and Kiyama H. Constitutive nitric oxide synthase is associated with retinal vascular permeability in early diabetic rats. Diabetologia 44 (2001) 1043-1050
45. Vernet D., Cai L., Garban H., Babbitt M.L., Murray F.T., Rajfer J., and Gonzalez-Cadavid N.F. Reduction of penile nitric oxide synthase in diabetic BB/WOR (type I) and BBZ/WOR (type II) rats with erectile dysfunction. Endocrinology 136 (1995) 5709-5717
46. Wei E.P., Christman C.W., Kontos H.A., and Povlishock J.T. Effects of oxygen radicals on cerebral arterioles. Am. J. Physiol. 248 (1985) H157-H162
47. Yu W.J., Juang S.W., Chin W.T., Chi T.C., Wu T.J., and Cheng J.T. Decrease of nitric oxide synthase in the cerebrocortex of streptozotocin-induced diabetic rats. Neurosci. Lett. 272 (1999) 99-102
48. Yu W.J., Juang S.W., Chin W.T., Chi T.C., Chang C.J., and Cheng J.T. Insulin restores neuronal nitric oxide synthase expression in streptozotocin-induced diabetic rats. Life Sci. 68 (2000) 625-634
49. Zheng H., Mayhan W.G., Bidasee K.R., and Patel K.P. Blunted nitric oxide-mediated inhibition of sympathetic nerve activity within the paraventricular nucleus in diabetic rats. Am. J. Physiol., Regul. Integr. Comp. Physiol. 290 (2006) R992-R1002
50. Zheng H., Bidasee K.R., Mayhan W.G., and Patel K.P. Lack of central nitric oxide triggers erectile dysfunction in diabetes. Am. J. Physiol., Regul. Integr. Comp. Physiol. 292 (2007) R1158-R1164
51. Zhu J., Mori T., Huang T., and Lombard J.H. Effect of high-salt diet on NO release and superoxide production in rat aorta. Am. J. Physiol, Heart Circ. Physiol. 286 (2004) H575-H583