Oxidation of NADPH on Kvβ1 inhibits ball-and-chain type inactivation by restraining the chain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 14, 2011, Pages 5885-5890

  Pan, Yaping ^a   Weng, Jun ^a   Levin, Elena J ^a   Zhou, Ming ^a  

^a Columbia University ^*  (United States)

Author keywords

Aldo keto reductase; Double mutant cycle analysis; Electrostatic interactions; Voltage dependent potassium channel

Indexed keywords

POTASSIUM CHANNEL KVBETA1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; POTASSIUM CHANNEL KV1.1; PRIMER DNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; RAT; REDOX STRESS; ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; DNA SEQUENCE; ELECTROPHYSIOLOGY; GENE VECTOR; GENETICS; METABOLISM; MOLECULAR CLONING; OXIDATION REDUCTION REACTION; POLYMERASE CHAIN REACTION; SPECTROFLUOROMETRY;

ANALYSIS OF VARIANCE; ANIMALS; CLONING, MOLECULAR; DNA PRIMERS; ELECTROPHYSIOLOGY; GENETIC VECTORS; KV1.1 POTASSIUM CHANNEL; NADP; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; RATS; SEQUENCE ANALYSIS, DNA; SPECTROMETRY, FLUORESCENCE;

EID: 79955036368     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1100316108     Document Type: Article

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