Progesterone administration modulates cortical TLR4/NF-B signaling pathway after subarachnoid hemorrhage in male rats

Mediators of Inflammation

Volumn 2011, Issue , 2011, Pages

  Fang, Qi ^a   Wang, Zhong ^a   Zuo, Gang ^a   Shi, Xiao Yong ^a   Zhang, Jian ^a   Chen, Gang ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROGESTERONE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; MONOCYTE CHEMOATTRACTANT PROTEIN 1 (66 77); MONOCYTE CHEMOATTRACTANT PROTEIN 1 (66-77); PEPTIDE FRAGMENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN EDEMA; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; UPREGULATION; ANIMAL; BRAIN; DISEASE MODEL; DRUG EFFECT; METABOLISM; PATHOLOGY;

ANIMALIA; RATTUS;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN EDEMA; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; NF-KAPPA B; PEPTIDE FRAGMENTS; PROGESTERONE; RATS; SIGNAL TRANSDUCTION; SUBARACHNOID HEMORRHAGE; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 79954989995     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2011/848309     Document Type: Article

References (35)

1. Cahill W. J., Calvert J. H., Zhang J. H., Mechanisms of early brain injury after subarachnoid hemorrhage Journal of Cerebral Blood Flow and Metabolism 2006 26 11 1341 1353 (Pubitemid 44629883)
2. Ostrowski R. P., Colohan A. R., Zhang J. H., Molecular mechanisms of early brain injury after subarachnoid hemorrhage Neurological Research 2006 28 4 399 414 (Pubitemid 43967787)
3. Ma C. X., Yin W. N., Cai B. O. W., Wu J., Wang J. Y., He M., Sun H., Ding J. L., You C., Toll-like receptor 4/nuclear factor-kappa B signaling detected in brain after early subarachnoid hemorrhage Chinese Medical Journal 2009 122 13 1575 1581
4. Ma C. X., Yin W. N., Cai B. W., Activation of TLR4/NF-kappaB signaling pathway in early brain injury after subarachnoid hemorrhage. Neurological Research. In press
5. Johnson G. B., Brunn G. J., Platt J. L., Activation of mammalian Toll-like receptors by endogenous agonists Critical Reviews in Immunology 2003 23 1-2 15 44 (Pubitemid 36875472)
6. Lee S. J., Lee S., Toll-like receptors and inflammation in the CNS Curr Drug Targets Inflamm Allergy 2002 1 2 181 191
7. Gibson C. L., Murphy S. P., Progesterone enhances functional recovery after middle cerebral artery occlusion in male mice Journal of Cerebral Blood Flow and Metabolism 2004 24 7 805 813 (Pubitemid 38880226)
8. Shahrokhi N., Khaksari M., Soltani Z., Mahmoodi M., Nakhaee N., Effect of sex steroid hormones on brain edema, intracranial pressure, and neurologic outcomes after traumatic brain injury Canadian Journal of Physiology and Pharmacology 2010 88 4 414 421
9. Chen G., Shi J., Jin W., Wang L., Xie W., Sun J., Hang C., Progesterone administration modulates TLRS/NF- B signaling pathway in rat brain after cortical contusion Annals of Clinical and Laboratory Science 2008 38 1 65 74 (Pubitemid 351323727)
10. Chen G., Shi J., Ding Y., Yin H., Hang C., Progesterone prevents traumatic brain injury-induced intestinal nuclear factor kappa B activation and proinflammatory cytokines expression in male rats Mediators of Inflammation 2007 2007 7
11. Wang Z., Chen G., Zhu W. W., Bian J. Y., Shen X. O., Zhou D., Influence of simvastatin on microthrombosis in the brain after subarachnoid hemorrhage in rats: a preliminary study Annals of Clinical and Laboratory Science 2010 40 1 32 42
12. Zhang J., Zhu Y., Zhou D., Wang Z., Chen G., Recombinant human erythropoietin (rhEPO) alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Nrf2-ARE pathway Cytokine 2010 52 3 252 257
13. Wang Z., Fang QI., Chen G., Zhu W., Dong W., Influence of melatonin on cerebrovascular proinflammatory mediators expression and oxidative stress following subarachnoid hemorrhage in rabbits Mediators of Inflammation 2009 2009 6
14. Yamaguchi M., Zhou C., Nanda A., Zhang J. H., Ras protein contributes to cerebral vasospasm in a canine double-hemorrhage model Stroke 2004 35 7 1750 1755 (Pubitemid 38823659)
15. Attella M. J., Nattinville A., Stein D. G., Hormonal state affects recovery from frontal cortex lesions in adult female rats Behavioral and Neural Biology 1987 48 3 352 367 (Pubitemid 17167117)
16. Groswasser Z., Cohen M., Keren O., Female TBI patients recover better than males Brain Injury 1998 12 9 805 808 (Pubitemid 28425306)
17. Al-Dahan M. I., Thalmann R. H., Progesterone regulates gamma-aminobutyric acid B (GABAB) receptors in the neocortex of female rats Brain Research 1996 727 1-2 40 48 (Pubitemid 26246812)
18. Concas A., Follesa P., Barbaccia M. L., Purdy R. H., Biggio G., Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites European Journal of Pharmacology 1999 375 13 225 235 (Pubitemid 29317607)
19. Bergeron R., De Montigny C., Debonnel G., Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors Journal of Neuroscience 1996 16 3 1193 1202 (Pubitemid 26140876)
20. Roof R. L., Hoffman S. W., Stein D. G., Progesterone protects against lipid peroxidation following traumatic brain injury in rats Molecular and Chemical Neuropathology 1997 31 1 1 11 (Pubitemid 27328632)
21. Duvdevani R., Roof R. L., Fulop Z., Hoffman S. W., Stein D. G., Blood-brain barrier breakdown and edema formation following frontal cortical contusion: does hormonal status play a role? Journal of Neurotrauma 1995 12 1 65 75
22. Roof R. L., Duvdevani R., Stein D. G., Progesterone treatment attenuates brain edema following contusion injury in male and female rats Restorative Neurology and Neuroscience 1992 4 7 425 427 (Pubitemid 23001029)
23. Roof R. L., Duvdevani R., Heyburn J. W., Stein D. G., Progesterone rapidly decreases brain edema: treatment delayed up to 24 hours is still effective Experimental Neurology 1996 138 2 246 251 (Pubitemid 26132712)
24. Roof R. L., Duvdevani R., Braswell L., Stein D. G., Progesterone facilitates cognitive recovery an reduces secondary neuronal loss caused by cortical contusion injury in male rats Experimental Neurology 1994 129 1 64 69 (Pubitemid 24344157)
25. Wright D. W., Ritchie J. C., Mullins R. E., Kellermann A. L., Denson D. D., Steady-state serum concentrations of progesterone following continuous intravenous infusion in patients with acute moderate to severe traumatic brain injury Journal of Clinical Pharmacology 2005 45 6 640 648 (Pubitemid 40696206)
26. Wright D. W., Kellermann A. L., Hertzberg V. S., Clark P. L., Frankel M., Goldstein F. C., Salomone J. P., Dent L. L., Harris O. A., Ander D. S., Lowery D. W., Patel M. M., Denson D. D., Gordon A. B., Wald M. M., Gupta S., Hoffman S. W., Stein D. G., ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury Annals of Emergency Medicine 2007 49 4 391 e2
27. Medzhitov R., Toll-like receptors and innate immunity Nature Reviews Immunology 2001 1 2 135 145 (Pubitemid 33741967)
28. Karik K., Weissman D., Welsh F. A., Inhibition of Toll-like receptor and cytokine signalinga unifying theme in ischemic tolerance Journal of Cerebral Blood Flow and Metabolism 2004 24 11 1288 1304 (Pubitemid 39482492)
29. Laflamme N., Rivest S., Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components FASEB Journal 2001 15 1 155 163 (Pubitemid 32061666)
30. Lehnardt S., Massillon L., Follett P., Jensen F. E., Ratan R., Rosenberg P. A., Volpe J. J., Vartanian T., Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway Proceedings of the National Academy of Sciences of the United States of America 2003 100 14 8514 8519 (Pubitemid 36842576)
31. Cristofaro P., Opal S. M., The Toll-like receptors and their role in septic shock Expert Opinion on Therapeutic Targets 2003 7 5 603 612 (Pubitemid 37258839)
32. Miettinen M., Sareneva T., Julkunen I., Matikainen S., IFNs activate toll-like receptor gene expression in viral infections Genes and Immunity 2001 2 6 349 355 (Pubitemid 33674248)
33. Aravalli R. N., Peterson P. K., Lokensgard J. R., Toll-like receptors in defense and damage of the central nervous system Journal of Neuroimmune Pharmacology 2007 2 4 297 312
34. Anderson M., Matthews K. B., Stuart J., Coagulation and fibrinolytic activity of cerebrospinal fluid Journal of Clinical Pathology 1978 31 5 488 492 (Pubitemid 8333050)
35. Klinge P. M., Beck H., Brinker T., Walter G. F., Samii M., Induction of heat shock protein 70 in the rat brain following intracisternal infusion of autologous blood: evaluation of acute neuronal damage Journal of Neurosurgery 1999 91 5 843 850 (Pubitemid 30053158)