Identification of spontaneous mutations within the long-range limb-specific Sonic hedgehog enhancer (ZRS) that alter Sonic hedgehog expression in the chicken limb mutants oligozeugodactyly and silkie breed

Developmental Dynamics

Volumn 240, Issue 5, 2011, Pages 1212-1222

  Maas, Sarah A ^a,b,c   Suzuki, Takayuki ^b,d,e   Fallon, John F ^b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c BRISTOL MYERS SQUIBB RESEARCH AND DEVELOPMENT   (United States)

^d NAGOYA UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Acheiropodia (ACHP); Cis enhancer; Dorking Breed chicken; Limb bud prepattern; Limb development; Mammals fishes conserved sequence 1 (MFCS 1); Oligozeugodactyly (ozd); Preaxial polydactyly (PPD); Reporter analysis; Silkie Breed chicken; Sonic hedgehog (SHH), LMBR1; Zone of polarizing activity (ZPA); ZPA regulatory sequence (ZRS)

Indexed keywords

BETA GALACTOSIDASE; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHICKEN; CONTROLLED STUDY; ELECTROPORATION; EMBRYO; GENE CONTROL; GENE DELETION; GENETIC IDENTIFICATION; IN VIVO GENE TRANSFER; LIMB BUD; NONHUMAN; OLIGOZEUGODACTYLY; POLYDACTYLY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY SEQUENCE; SPONTANEOUS MUTATION; ZONE OF POLARIZING ACTIVITY REGULATORY SEQUENCE;

ANIMALS; CHICK EMBRYO; CHICKENS; ENHANCER ELEMENTS, GENETIC; EXTREMITIES; HEDGEHOG PROTEINS; LIMB BUDS; MUTATION; POLYDACTYLY;

ERINACEIDAE; MAMMALIA; PISCES;

EID: 79954988557     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22634     Document Type: Article

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