메뉴 건너뛰기




Volumn 10, Issue 1, 2011, Pages 119-132

The emerging role of melatonin agonists in the treatment of major depression: Focus on agomelatine

Author keywords

Agomelatine; Circadian rhythms; Efficacy; Major depressive disorder; Melatonin; Tolerability; Treatment

Indexed keywords

AGOMELATINE; FLUOXETINE; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; PAROXETINE; PLACEBO; SERTRALINE; VENLAFAXINE; ACETAMIDE DERIVATIVE; ANTIDEPRESSANT AGENT;

EID: 79954633976     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/187152711794488674     Document Type: Review
Times cited : (64)

References (153)
  • 1
    • 38049081662 scopus 로고    scopus 로고
    • Major depressive disorder
    • Belmaker, R.H.; Agam, G. Major depressive disorder. N. Engl. J. Med., 2008, 358, 55-68
    • (2008) N. Engl. J. Med , vol.358 , pp. 55-68
    • Belmaker, R.H.1    Agam, G.2
  • 2
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler, R.C.; Berglund, P.; Demler, O.; Jin, R.; Merikangas, K.R.; Walters, E.E. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry, 2005, 62, 593-602
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 3
    • 20344374645 scopus 로고    scopus 로고
    • Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler, R.C.; Chiu, W.T.; Demler, O.; Merikangas, K.R.; Walters, E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry, 2005, 62, 617-627
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 617-627
    • Kessler, R.C.1    Chiu, W.T.2    Demler, O.3    Merikangas, K.R.4    Walters, E.E.5
  • 4
    • 76149083587 scopus 로고    scopus 로고
    • Severe depression: Genes and the environment
    • Gorwood P. Severe depression: genes and the environment. Encephale, 2009, 35(Suppl 7), 306-309
    • (2009) Encephale , vol.35 , Issue.7 SUPPL. , pp. 306-309
    • Gorwood, P.1
  • 5
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan, V.; Nestler, E.J. The molecular neurobiology of depression. Nature, 2008, 16, 894-902
    • (2008) Nature , vol.16 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 6
    • 77951224423 scopus 로고    scopus 로고
    • The efficacy, tolerability, and safety of contemporary antidepressants
    • Papakostas, G.I. The efficacy, tolerability, and safety of contemporary antidepressants. J. Clin. Psychiatry, 2010, 71(Suppl E1), e03
    • (2010) J. Clin. Psychiatry , vol.71 , Issue.1 SUPPL.
    • Papakostas, G.I.1
  • 9
    • 67649289851 scopus 로고    scopus 로고
    • Treatment-emergent sexual dysfunction related to antidepressants: A meta-analysis
    • Serretti, A.; Chiesa, A. Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis. J. Clin. Psychopharmacol., 2009, 29, 259-266
    • (2009) J. Clin. Psychopharmacol , vol.29 , pp. 259-266
    • Serretti, A.1    Chiesa, A.2
  • 12
    • 77955128272 scopus 로고    scopus 로고
    • Agomelatine, a melatonin agonist with antidepressant properties
    • Dubovsky, S.L.; Warren, C. Agomelatine, a melatonin agonist with antidepressant properties. Expert Opin. Investig. Drugs, 2009, 18, 1533-1540
    • (2009) Expert Opin. Investig. Drugs , vol.18 , pp. 1533-1540
    • Dubovsky, S.L.1    Warren, C.2
  • 13
    • 70350736706 scopus 로고    scopus 로고
    • Neurobiology of circadian systems
    • Schulz, P.; Steimer, T. Neurobiology of circadian systems. CNS Drugs, 2009, 23(Suppl 2), 3-13
    • (2009) CNS Drugs , vol.23 , Issue.1 SUPPL. , pp. 3-13
    • Schulz, P.1    Steimer, T.2
  • 14
    • 70449382547 scopus 로고    scopus 로고
    • The regulation of central and peripheral circadian clocks in humans
    • Cermakian, N.; Boivin, D.B. The regulation of central and peripheral circadian clocks in humans. Obes. Rev., 2009, 10(Suppl 2), 25-36
    • (2009) Obes. Rev , vol.10 , Issue.1 SUPPL. , pp. 25-36
    • Cermakian, N.1    Boivin, D.B.2
  • 15
    • 14644435678 scopus 로고    scopus 로고
    • The hypothalamic integrator for circadian rhythms
    • Saper, C.B.; Lu, J.; Chou, T.C.; Gooley, J. The hypothalamic integrator for circadian rhythms. Trends Neurosci., 2005, 28, 152-157
    • (2005) Trends Neurosci , vol.28 , pp. 152-157
    • Saper, C.B.1    Lu, J.2    Chou, T.C.3    Gooley, J.4
  • 16
    • 54749103977 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus and melatonin: Reciprocal interactions and clinical correlations
    • Benarroch, E.E. Suprachiasmatic nucleus and melatonin: reciprocal interactions and clinical correlations. Neurology, 2008, 71, 594-598
    • (2008) Neurology , vol.71 , pp. 594-598
    • Benarroch, E.E.1
  • 17
    • 0031040501 scopus 로고    scopus 로고
    • Circadian rhythms: Basic neurobiology and clinical applications
    • Moore, R.Y. Circadian rhythms: basic neurobiology and clinical applications. Annu. Rev. Med., 1997, 48, 253-266
    • (1997) Annu. Rev. Med , vol.48 , pp. 253-266
    • Moore, R.Y.1
  • 18
    • 70450173299 scopus 로고    scopus 로고
    • Weather and seasons together demand complex biological clocks
    • Troein, C.; Locke, J.C.; Turner, M.S.; Millar, A.J. Weather and seasons together demand complex biological clocks. Curr. Biol., 2009, 19, 1961-1964
    • (2009) Curr. Biol , vol.19 , pp. 1961-1964
    • Troein, C.1    Locke, J.C.2    Turner, M.S.3    Millar, A.J.4
  • 19
    • 33846239400 scopus 로고    scopus 로고
    • The brain's master circadian clock: Implications and opportunities for therapy of sleep disorders
    • Zee, P.C.; Manthena, P. The brain's master circadian clock: implications and opportunities for therapy of sleep disorders. Sleep Med. Rev., 2007, 11, 59-70
    • (2007) Sleep Med. Rev , vol.11 , pp. 59-70
    • Zee, P.C.1    Manthena, P.2
  • 20
    • 0038042355 scopus 로고    scopus 로고
    • A phase response curve to single bright light pulses in human subjects
    • Khalsa, S.B.; Jewett, M.E.; Cajochen, C.; Czeisler, C.A. A phase response curve to single bright light pulses in human subjects. J. Physiol., 2003, 549, 945-952
    • (2003) J. Physiol , vol.549 , pp. 945-952
    • Khalsa, S.B.1    Jewett, M.E.2    Cajochen, C.3    Czeisler, C.A.4
  • 21
    • 73649092106 scopus 로고    scopus 로고
    • The crosstalk between physiology and circadian clock proteins
    • Duguay, D.; Cermakian, N. The crosstalk between physiology and circadian clock proteins. Chronobiol. Int., 2009, 26, 1479-1513
    • (2009) Chronobiol. Int , vol.26 , pp. 1479-1513
    • Duguay, D.1    Cermakian, N.2
  • 22
    • 0141509017 scopus 로고    scopus 로고
    • Peripheral circadian oscillators in mammals: Time and food
    • Schibler, U.; Ripperger, J.; Brown, S.A. Peripheral circadian oscillators in mammals: time and food. J. Biol. Rhythms, 2003, 18, 250-260
    • (2003) J. Biol. Rhythms , vol.18 , pp. 250-260
    • Schibler, U.1    Ripperger, J.2    Brown, S.A.3
  • 23
  • 25
    • 10444245917 scopus 로고    scopus 로고
    • Human pineal physiology and functional significance of melatonin
    • Macchi, M.M.; Bruce, J.N. Human pineal physiology and functional significance of melatonin. Front. Neuroendocrinol., 2004, 25, 177-195
    • (2004) Front. Neuroendocrinol , vol.25 , pp. 177-195
    • Macchi, M.M.1    Bruce, J.N.2
  • 26
    • 36749066274 scopus 로고    scopus 로고
    • In search of novel and therapeutically significant melatoninergic ligands
    • Mody, S.M.; Hu, Y.; Ho, M.K.; Wong, Y.H. In search of novel and therapeutically significant melatoninergic ligands. Recent Pat. CNS Drug. Discov., 2007, 2, 241-245
    • (2007) Recent Pat. CNS Drug. Discov , vol.2 , pp. 241-245
    • Mody, S.M.1    Hu, Y.2    Ho, M.K.3    Wong, Y.H.4
  • 27
    • 0029972613 scopus 로고    scopus 로고
    • Melatonin receptors step into the light: Cloning and classification of subtypes
    • Reppert, S.M.; Weaver, D.R.; Godson, C. Melatonin receptors step into the light: cloning and classification of subtypes. Trends Pharmacol. Sci., 1996, 17, 100-102
    • (1996) Trends Pharmacol. Sci , vol.17 , pp. 100-102
    • Reppert, S.M.1    Weaver, D.R.2    Godson, C.3
  • 28
    • 3242662870 scopus 로고    scopus 로고
    • Molecular pharmacology, regulation and function of mammalian melatonin receptors
    • Dubocovich, M.L.; Rivera-Bermudez, M.A.; Gerdin, M.J.; Masana, M.I. Molecular pharmacology, regulation and function of mammalian melatonin receptors. Front. Biosci., 2003, 8, 101-108
    • (2003) Front. Biosci , vol.8 , pp. 101-108
    • Dubocovich, M.L.1    Rivera-Bermudez, M.A.2    Gerdin, M.J.3    Masana, M.I.4
  • 29
    • 0037418623 scopus 로고    scopus 로고
    • Melatonin receptors and their regulation: Biochemical and structural mechanisms
    • Witt-Enderby, P.A.; Bennett, J.; Jarzynka, M.J.; Firestine, S.; Melan, M.A. Melatonin receptors and their regulation: biochemical and structural mechanisms. Life Sci., 2003, 72, 2183-2198
    • (2003) Life Sci , vol.72 , pp. 2183-2198
    • Witt-Enderby, P.A.1    Bennett, J.2    Jarzynka, M.J.3    Firestine, S.4    Melan, M.A.5
  • 30
    • 0030761518 scopus 로고    scopus 로고
    • Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock
    • Liu, C.; Weaver, D.R.; Jin, X.; Shearman, L.P.; Pieschl, R.L.; Gribkoff, V.K.; Reppert, S.M. Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron, 1997, 19, 91-102
    • (1997) Neuron , vol.19 , pp. 91-102
    • Liu, C.1    Weaver, D.R.2    Jin, X.3    Shearman, L.P.4    Pieschl, R.L.5    Gribkoff, V.K.6    Reppert, S.M.7
  • 31
    • 0035834811 scopus 로고    scopus 로고
    • Melatonin generates an outward potassium current in rat suprachiasmatic nucleus neurones in vitro independent of their circadian rhythm
    • Van den Top, M.; Buijs, R.M.; Ruijter, J.M.; Delagrange, P.; Spanswick, D.; Hermes, M.L. Melatonin generates an outward potassium current in rat suprachiasmatic nucleus neurones in vitro independent of their circadian rhythm. Neuroscience, 2001, 107, 99-108
    • (2001) Neuroscience , vol.107 , pp. 99-108
    • van den Top, M.1    Buijs, R.M.2    Ruijter, J.M.3    Delagrange, P.4    Spanswick, D.5    Hermes, M.L.6
  • 32
    • 38949209106 scopus 로고    scopus 로고
    • Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus
    • von Gall, C.; Weaver, D.R. Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus. Neurobiol. Aging, 2008, 29, 464-470
    • (2008) Neurobiol. Aging , vol.29 , pp. 464-470
    • von Gall, C.1    Weaver, D.R.2
  • 33
    • 0029788185 scopus 로고    scopus 로고
    • Melatonin effects on behavior: Possible mediation by the central GABAergic system
    • Golombek, D.A.; Pévet, P.; Cardinali, D.P. Melatonin effects on behavior: possible mediation by the central GABAergic system. Neurosci. Biobehav. Rev., 1996, 20, 403-412
    • (1996) Neurosci. Biobehav. Rev , vol.20 , pp. 403-412
    • Golombek, D.A.1    Pévet, P.2    Cardinali, D.P.3
  • 34
    • 67651151194 scopus 로고    scopus 로고
    • Physiology and pharmacology of melatonin in relation to biological rhythms
    • Zawilska, J.B.; Skene, D.J.; Arendt, J. Physiology and pharmacology of melatonin in relation to biological rhythms. Pharmacol. Rep., 2009, 61, 383-410
    • (2009) Pharmacol. Rep , vol.61 , pp. 383-410
    • Zawilska, J.B.1    Skene, D.J.2    Arendt, J.3
  • 35
    • 0032161469 scopus 로고    scopus 로고
    • Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
    • Dubocovich, M.L.; Yun, K.; Al-Ghoul, W.M.; Benloucif, S.; Masana, M.I. Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J., 1998, 12, 1211-1220
    • (1998) FASEB J , vol.12 , pp. 1211-1220
    • Dubocovich, M.L.1    Yun, K.2    Al-Ghoul, W.M.3    Benloucif, S.4    Masana, M.I.5
  • 36
    • 0035008125 scopus 로고    scopus 로고
    • Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock
    • Hunt, A.E.; Al-Ghoul, W.M.; Gillette, M.U.; Dubocovich, M.L. Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock. Am. J. Physiol. Cell Physiol., 2001, 280, 110-118
    • (2001) Am. J. Physiol. Cell Physiol , vol.280 , pp. 110-118
    • Hunt, A.E.1    Al-Ghoul, W.M.2    Gillette, M.U.3    Dubocovich, M.L.4
  • 37
    • 0033621791 scopus 로고    scopus 로고
    • Circadian rhythm of MT1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse
    • Masana, M.I.; Benloucif, S.; Dubocovich, M.L. Circadian rhythm of MT1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse. J. Pineal Res., 2000, 28, 185-192
    • (2000) J. Pineal Res , vol.28 , pp. 185-192
    • Masana, M.I.1    Benloucif, S.2    Dubocovich, M.L.3
  • 38
    • 0037047464 scopus 로고    scopus 로고
    • MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei
    • Poirel, V.J.; Masson-Pévet, M.; Pevét, P.; Gauer, F. MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei. Brain Res., 2002, 946, 64-71
    • (2002) Brain Res , vol.946 , pp. 64-71
    • Poirel, V.J.1    Masson-Pévet, M.2    Pevét, P.3    Gauer, F.4
  • 39
    • 0344442759 scopus 로고    scopus 로고
    • The suprachiasmatic nucleus: A clock of multiple components
    • Lee, H.S.; Billings, H.J.; Lehman, M.N. The suprachiasmatic nucleus: a clock of multiple components. J. Biol. Rhythms, 2003, 18, 435-449
    • (2003) J. Biol. Rhythms , vol.18 , pp. 435-449
    • Lee, H.S.1    Billings, H.J.2    Lehman, M.N.3
  • 40
    • 36348977007 scopus 로고    scopus 로고
    • Entrainment of the suprachiasmatic clockwork in diurnal and nocturnal mammals
    • Challet, E. Entrainment of the suprachiasmatic clockwork in diurnal and nocturnal mammals. Endocrinology, 2007, 148, 5648-5655
    • (2007) Endocrinology , vol.148 , pp. 5648-5655
    • Challet, E.1
  • 42
    • 34948847559 scopus 로고    scopus 로고
    • From circadian rhythms to clock genes in depression
    • Turek, F.W. From circadian rhythms to clock genes in depression. Int. Clin. Psychopharmacol., 2007, 22(Suppl 2), 1-8
    • (2007) Clin. Psychopharmacol , vol.22 , Issue.1 SUPPL. , pp. 1-8
    • Turek, F.W.1
  • 44
    • 33748179340 scopus 로고    scopus 로고
    • The social zeitgeber theory, circadian rhythms, and mood disorders: Review and evaluation
    • Grandin, L.D.; Alloy, L.B.; Abramson, L.Y. The social zeitgeber theory, circadian rhythms, and mood disorders: review and evaluation. Clin. Psychol. Rev., 2006, 26, 679-694
    • (2006) Clin. Psychol. Rev , vol.26 , pp. 679-694
    • Grandin, L.D.1    Alloy, L.B.2    Abramson, L.Y.3
  • 45
    • 34447292291 scopus 로고    scopus 로고
    • Diurnal mood variation in depression: A signal of disturbed circadian function
    • Murray, G. Diurnal mood variation in depression: a signal of disturbed circadian function? J. Affect. Disord., 2007, 102, 47-53
    • (2007) J. Affect. Disord , vol.102 , pp. 47-53
    • Murray, G.1
  • 46
    • 0025139158 scopus 로고
    • Circadian rhythms in depression. Part II: Circadian rhythms in inpatients with various mental disorders
    • Tsujimoto, T.; Yamada, N.; Shimoda, K.; Kanada, K.; Takahashi, S. Circadian rhythms in depression. Part II: circadian rhythms in inpatients with various mental disorders. J. Affect. Disord., 1990, 18, 199-210
    • (1990) J. Affect. Disord , vol.18 , pp. 199-210
    • Tsujimoto, T.1    Yamada, N.2    Shimoda, K.3    Kanada, K.4    Takahashi, S.5
  • 47
    • 70350703394 scopus 로고    scopus 로고
    • Disruption of the circadian timing systems: Molecular mechanisms in mood disorders
    • Mendlewicz, J. Disruption of the circadian timing systems: molecular mechanisms in mood disorders. CNS Drugs, 2009, 23(Suppl 2), 15-26
    • (2009) CNS Drugs , vol.23 , Issue.2 SUPPL. , pp. 15-26
    • Mendlewicz, J.1
  • 48
    • 0029941919 scopus 로고    scopus 로고
    • Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol
    • Van Cauter, E.; Leproult, R.; Kupfer, D.J. Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol. J. Clin. Endocrinol. Metab., 1996, 81, 2468-2473
    • (1996) J. Clin. Endocrinol. Metab , vol.81 , pp. 2468-2473
    • van Cauter, E.1    Leproult, R.2    Kupfer, D.J.3
  • 50
    • 0026710105 scopus 로고
    • NE uptake inhibition increases melatonin secretion, a measure of noradrenergic neurotransmission, in depressed patients
    • Palazidou, E.; Papadopoulos, A.; Ratcliff, H.; Dawling, S.; Checkley, S.A. NE uptake inhibition increases melatonin secretion, a measure of noradrenergic neurotransmission, in depressed patients. Psychol. Med., 1992, 22, 309-315
    • (1992) Psychol. Med , vol.22 , pp. 309-315
    • Palazidou, E.1    Papadopoulos, A.2    Ratcliff, H.3    Dawling, S.4    Checkley, S.A.5
  • 51
    • 74149087990 scopus 로고    scopus 로고
    • Good night and good luck: Norepinephrine in sleep pharmacology
    • Mitchell, H.A.; Weinshenker, D. Good night and good luck: norepinephrine in sleep pharmacology. Biochem. Pharmacol., 2009, 79(6), 801-809
    • (2009) Biochem. Pharmacol , vol.79 , Issue.6 , pp. 801-809
    • Mitchell, H.A.1    Weinshenker, D.2
  • 53
    • 33746678017 scopus 로고    scopus 로고
    • Melatonin levels in drug-free patients with major depression from the southern hemisphere
    • Carvalho, L.A.; Gorenstein, C.; Moreno, R.A.; Markus, R.P. Melatonin levels in drug-free patients with major depression from the southern hemisphere. Psychoneuroendocrinology, 2006, 31, 761-768
    • (2006) Psychoneuroendocrinology , vol.31 , pp. 761-768
    • Carvalho, L.A.1    Gorenstein, C.2    Moreno, R.A.3    Markus, R.P.4
  • 56
    • 0018559581 scopus 로고
    • Clinical importance of melatonin
    • Wetterberg, L. Clinical importance of melatonin. Prog. Brain Res., 1979, 52, 539-547
    • (1979) Prog. Brain Res , vol.52 , pp. 539-547
    • Wetterberg, L.1
  • 57
    • 0021636815 scopus 로고
    • A chronobiological study of melatonin and cortisol secretion in depressed subjects: Plasma melatonin, a biochemical marker in major depression
    • Claustrat, B.; Chazot, G.; Brun, J.; Jordan, D.; Sassolas, G. A chronobiological study of melatonin and cortisol secretion in depressed subjects: plasma melatonin, a biochemical marker in major depression. Biol. Psychiatry, 1984, 19, 1215-1228
    • (1984) Biol. Psychiatry , vol.19 , pp. 1215-1228
    • Claustrat, B.1    Chazot, G.2    Brun, J.3    Jordan, D.4    Sassolas, G.5
  • 59
    • 0021864818 scopus 로고
    • Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects
    • Brown, R.; Kocsis, J.H.; Caroff, S.; Amsterdam, J.; Winokur, A.; Stokes, P.E.; Frazer, A. Differences in nocturnal melatonin secretion between melancholic depressed patients and control subjects. Am. J. Psychiatry, 1985, 142, 811-816
    • (1985) Am. J. Psychiatry , vol.142 , pp. 811-816
    • Brown, R.1    Kocsis, J.H.2    Caroff, S.3    Amsterdam, J.4    Winokur, A.5    Stokes, P.E.6    Frazer, A.7
  • 60
    • 0021915998 scopus 로고
    • Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome
    • Beck-Friis, J.; Kjellman, B.F.; Aperia, B.; Undén, F.; von Rosen, D.; Ljunggren, J.G.; Wetterberg, L. Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome. Acta Psychiatr. Scand., 1985, 71, 319-330
    • (1985) Acta Psychiatr. Scand , vol.71 , pp. 319-330
    • Beck-Friis, J.1    Kjellman, B.F.2    Aperia, B.3    Undén, F.4    von Rosen, D.5    Ljunggren, J.G.6    Wetterberg, L.7
  • 61
    • 0024061143 scopus 로고
    • The phase-shift hypothesis of seasonal affective disorder
    • Lewy, A.J.; Sack, R.L. The phase-shift hypothesis of seasonal affective disorder. Am. J. Psychiatry, 1988, 145, 1041-1043
    • (1988) Am. J. Psychiatry , vol.145 , pp. 1041-1043
    • Lewy, A.J.1    Sack, R.L.2
  • 62
    • 0026710562 scopus 로고
    • Neuroendocrine aspects of primary endogenous depression. XI. Serum melatonin measures in patients and matched control subjects
    • Rubin, R.T.; Heist, E.K.; McGeoy, S.S.; Hanada, K.; Lesser, I.M. Neuroendocrine aspects of primary endogenous depression. XI. Serum melatonin measures in patients and matched control subjects. Arch. Gen. Psychiatry, 1992, 49, 558-567
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 558-567
    • Rubin, R.T.1    Heist, E.K.2    McGeoy, S.S.3    Hanada, K.4    Lesser, I.M.5
  • 64
    • 0030900711 scopus 로고    scopus 로고
    • Neuroendocrine aspects of primary endogenous depression. XV: Mathematical modeling of nocturnal melatonin secretion in major depressives and normal controls
    • Sekula, L.K.; Lucke, J.F.; Heist, E.K.; Czambel, R.K.; Rubin, R.T. Neuroendocrine aspects of primary endogenous depression. XV: Mathematical modeling of nocturnal melatonin secretion in major depressives and normal controls. Psychiatry Res., 1997, 69, 143-153
    • (1997) Psychiatry Res , vol.69 , pp. 143-153
    • Sekula, L.K.1    Lucke, J.F.2    Heist, E.K.3    Czambel, R.K.4    Rubin, R.T.5
  • 66
    • 85047689184 scopus 로고    scopus 로고
    • A forced desynchrony study of circadian pacemaker characteristics in seasonal affective disorder
    • Koorengevel, K.M.; Beersma, D.G.; den Boer, J.A.; van den Hoofdakker, R.H. A forced desynchrony study of circadian pacemaker characteristics in seasonal affective disorder. J. Biol. Rhythms, 2002, 17, 463-475
    • (2002) J. Biol. Rhythms , vol.17 , pp. 463-475
    • Koorengevel, K.M.1    Beersma, D.G.2    den Boer, J.A.3    van den Hoofdakker, R.H.4
  • 67
    • 1942436030 scopus 로고    scopus 로고
    • Etiology, pathogenesis, and treatment of seasonal and nonseasonal mood disorders: Possible role of circadian rhythm abnormalities related to developmental alcohol exposure
    • Sher, L. Etiology, pathogenesis, and treatment of seasonal and nonseasonal mood disorders: possible role of circadian rhythm abnormalities related to developmental alcohol exposure. Med. Hypotheses, 2004, 62, 797-801
    • (2004) Med. Hypotheses , vol.62 , pp. 797-801
    • Sher, L.1
  • 68
    • 34247600816 scopus 로고    scopus 로고
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder, American Psychiatric Press: Washington, DC
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorder, Text Revision (DSM-IV-TR); American Psychiatric Press: Washington, DC, 2000
    • (2000) Text Revision (DSM-IV-TR)
  • 69
    • 24144462496 scopus 로고    scopus 로고
    • Update on the biology of seasonal affective disorder
    • Sohn, C.H.; Lam, R.W. Update on the biology of seasonal affective disorder. CNS Spectr., 2005, 10, 635-646
    • (2005) CNS Spectr , vol.10 , pp. 635-646
    • Sohn, C.H.1    Lam, R.W.2
  • 70
    • 0036483407 scopus 로고    scopus 로고
    • Differences in prevalence of seasonal affective disorder that are not explained by either genetic or latitude differences
    • Axelsson, J.; Káradóttir, R.; Karlsson, M.M. Differences in prevalence of seasonal affective disorder that are not explained by either genetic or latitude differences. Int. J. Circumpolar Health, 2002, 61, 17-20
    • (2002) J. Circumpolar Health , vol.61 , pp. 17-20
    • Axelsson, J.1    Káradóttir, R.2    Karlsson, M.M.3
  • 71
    • 0037275237 scopus 로고    scopus 로고
    • Seasonal affective disorder: An overview
    • Magnusson, A.; Boivin, D. Seasonal affective disorder: an overview. Chronobiol. Int., 2003, 20, 189-207
    • (2003) Chronobiol. Int. , vol.20 , pp. 189-207
    • Magnusson, A.1    Boivin, D.2
  • 73
    • 0032535994 scopus 로고    scopus 로고
    • Melatonin treatment of winter depression: A pilot study
    • Lewy, A.J.; Bauer, V.K.; Cutler, N.L.; Sack, R.L. Melatonin treatment of winter depression: a pilot study. Psychiatry Res., 1998, 77, 57-61
    • (1998) Psychiatry Res , vol.77 , pp. 57-61
    • Lewy, A.J.1    Bauer, V.K.2    Cutler, N.L.3    Sack, R.L.4
  • 74
    • 0025309724 scopus 로고
    • Morning vs evening light treatment for winter depression. Evidence that the therapeutic effects of light are mediated by circadian phase shifts
    • Sack, R.L.; Lewy, A.J.; White, D.M.; Singer, C.M.; Fireman, M.J.; Vandiver, R. Morning vs evening light treatment for winter depression. Evidence that the therapeutic effects of light are mediated by circadian phase shifts. Arch. Gen. Psychiatry, 1990, 47, 343-351
    • (1990) Arch. Gen. Psychiatry , vol.47 , pp. 343-351
    • Sack, R.L.1    Lewy, A.J.2    White, D.M.3    Singer, C.M.4    Fireman, M.J.5    Vandiver, R.6
  • 79
    • 11844293488 scopus 로고    scopus 로고
    • Melatonin as a chronobiotic
    • Arendt, J.; Skene, D.J. Melatonin as a chronobiotic. Sleep Med. Rev., 2005, 9, 25-39
    • (2005) Sleep Med. Rev , vol.9 , pp. 25-39
    • Arendt, J.1    Skene, D.J.2
  • 80
    • 33645498696 scopus 로고    scopus 로고
    • The use of chronobiotics in the resynchronization of the sleep-wake cycle
    • Cardinali, D.P.; Furio, A.M.; Reyes, M.P.; Brusco, L.I. The use of chronobiotics in the resynchronization of the sleep-wake cycle. Cancer Causes Control, 2006, 17, 601-609
    • (2006) Cancer Causes Control , vol.17 , pp. 601-609
    • Cardinali, D.P.1    Furio, A.M.2    Reyes, M.P.3    Brusco, L.I.4
  • 81
    • 0035140797 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome
    • Kayumov, L.; Brown, G.; Jindal, R.; Buttoo, K.; Shapiro, C.M. A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome. Psychosom. Med., 2001, 63, 40-48
    • (2001) Psychosom. Med , vol.63 , pp. 40-48
    • Kayumov, L.1    Brown, G.2    Jindal, R.3    Buttoo, K.4    Shapiro, C.M.5
  • 82
    • 57449090148 scopus 로고    scopus 로고
    • Agomelatine treatment of major depressive disorder
    • Dolder, C.R.; Nelson, M.; Snider, M. Agomelatine treatment of major depressive disorder. Ann. Pharmacother., 2008, 42, 1822-1831
    • (2008) Ann. Pharmacother , vol.42 , pp. 1822-1831
    • Dolder, C.R.1    Nelson, M.2    Snider, M.3
  • 85
    • 0041932292 scopus 로고    scopus 로고
    • The novel melatonin agonist agomelatine (S20098) is an antagonist at 5- hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways
    • Millan, M.J.; Gobert, A.; Lejeune, F.; Dekeyne, A.; Newman- Tancredi, A.; Pasteau, V.; Rivet, J.M.; Cussac, D. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5- hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J. Pharmacol. Exp. Ther., 2003, 306, 954-964
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , pp. 954-964
    • Millan, M.J.1    Gobert, A.2    Lejeune, F.3    Dekeyne, A.4    Newman-Tancredi, A.5    Pasteau, V.6    Rivet, J.M.7    Cussac, D.8
  • 86
    • 0031024060 scopus 로고    scopus 로고
    • Evidence for expression of the 5- hydroxy-trypamine-2B receptor profile in the rat central nervous system
    • Duxon, M.S.; Flanigan, T.P.; Reavley, A.C.; Baxter, G.S.; Blackburn, T.P.; Fone, K.C. Evidence for expression of the 5- hydroxy-trypamine-2B receptor profile in the rat central nervous system. Neuroscience, 1997, 76, 323-329
    • (1997) Neuroscience , vol.76 , pp. 323-329
    • Duxon, M.S.1    Flanigan, T.P.2    Reavley, A.C.3    Baxter, G.S.4    Blackburn, T.P.5    Fone, K.C.6
  • 87
    • 33745795154 scopus 로고    scopus 로고
    • Drug evaluation: Agomelatine targets a range of major depressive disorder symptoms
    • Dubocovich, M.L. Drug evaluation: agomelatine targets a range of major depressive disorder symptoms. Curr. Opin. Investig. Drugs, 2006, 7, 670-680
    • (2006) Curr. Opin. Investig. Drugs , vol.7 , pp. 670-680
    • Dubocovich, M.L.1
  • 88
    • 34948820516 scopus 로고    scopus 로고
    • Asymmetric expression of melatonin receptor mRNA in bilateral paravertebral muscles in adolescent idiopathic scoliosis
    • Wu, L.; Qiu, Y.; Wang, B.; Yu, Y.; Zhu, Z. Asymmetric expression of melatonin receptor mRNA in bilateral paravertebral muscles in adolescent idiopathic scoliosis. Stud. Health Technol. Inform., 2006, 123, 129-134
    • (2006) Stud. Health Technol. Inform , vol.123 , pp. 129-134
    • Wu, L.1    Qiu, Y.2    Wang, B.3    Yu, Y.4    Zhu, Z.5
  • 89
    • 0023724123 scopus 로고
    • The electrophysiological effects of melatonin and a putative melatonin antagonist (N-acetyltryptamine) on rat suprachiasmatic neurones in vitro
    • Mason, R.; Brooks, A. The electrophysiological effects of melatonin and a putative melatonin antagonist (N-acetyltryptamine) on rat suprachiasmatic neurones in vitro. Neurosci. Lett., 1988, 95, 296-301
    • (1988) Neurosci. Lett , vol.95 , pp. 296-301
    • Mason, R.1    Brooks, A.2
  • 90
    • 11844277100 scopus 로고    scopus 로고
    • The basic physiology and pathophysiology of melatonin
    • Claustrat, B.; Brun, J.; Chazot, G. The basic physiology and pathophysiology of melatonin. Sleep. Med. Rev., 2005, 9, 11-24
    • (2005) Sleep. Med. Rev , vol.9 , pp. 11-24
    • Claustrat, B.1    Brun, J.2    Chazot, G.3
  • 91
    • 0033609683 scopus 로고    scopus 로고
    • Immunohistochemical localization of serotonin receptors in the rat suprachiasmatic nucleus
    • Moyer, R.W.; Kennaway, D.J. Immunohistochemical localization of serotonin receptors in the rat suprachiasmatic nucleus. Neurosci. Lett., 1999, 271, 147-150
    • (1999) Neurosci. Lett , vol.271 , pp. 147-150
    • Moyer, R.W.1    Kennaway, D.J.2
  • 93
    • 30344467797 scopus 로고    scopus 로고
    • Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety
    • Papp, M.; Litwa, E.; Gruca, P.; Mocaer, E. Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety. Behav. Pharmacol., 2006, 17, 9-18
    • (2006) Behav. Pharmacol , vol.17 , pp. 9-18
    • Papp, M.1    Litwa, E.2    Gruca, P.3    Mocaer, E.4
  • 94
    • 0038050606 scopus 로고    scopus 로고
    • Effect of agomelatine in the chronic mild stress model of depression in the rat
    • Papp, M.; Gruca, P.; Boyer, P.A.; Mocaer, E. Effect of agomelatine in the chronic mild stress model of depression in the rat. Neuropsychopharmacology, 2003, 28, 694-703
    • (2003) Neuropsychopharmacology , vol.28 , pp. 694-703
    • Papp, M.1    Gruca, P.2    Boyer, P.A.3    Mocaer, E.4
  • 95
    • 33645452696 scopus 로고    scopus 로고
    • Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
    • Millan, M.J. Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application. Pharmacol. Ther., 2006, 110, 135-370
    • (2006) Pharmacol. Ther , vol.110 , pp. 135-370
    • Millan, M.J.1
  • 96
    • 33845482495 scopus 로고    scopus 로고
    • Agomelatine: A preliminary review of a new antidepressant
    • Zupancic, M.; Guilleminault, C. Agomelatine: a preliminary review of a new antidepressant. CNS Drugs, 2006, 20, 981-992
    • (2006) CNS Drugs , vol.20 , pp. 981-992
    • Zupancic, M.1    Guilleminault, C.2
  • 97
    • 4544281385 scopus 로고    scopus 로고
    • Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain
    • Hanoun, N.; Mocaer, E.; Boyer, P.A.; Hamon, M.; Lanfumey, L. Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology, 2004, 47, 515-526
    • (2004) Neuropharmacology , vol.47 , pp. 515-526
    • Hanoun, N.1    Mocaer, E.2    Boyer, P.A.3    Hamon, M.4    Lanfumey, L.5
  • 98
    • 51449124059 scopus 로고    scopus 로고
    • Agomelatine: A novel mechanism of antidepressant action involving the melatonergic and the serotonergic system
    • San, L.; Arranz, B. Agomelatine: a novel mechanism of antidepressant action involving the melatonergic and the serotonergic system. Eur. Psychiatry, 2008, 23, 396-402
    • (2008) Eur. Psychiatry , vol.23 , pp. 396-402
    • San, L.1    Arranz, B.2
  • 99
    • 33646692559 scopus 로고    scopus 로고
    • Effect of agomelatine on the sleep EEG in patients with major depressive disorders (MDD)
    • Quera-Salva, M.A.; Vanier, B.; Chapotot, F. Effect of agomelatine on the sleep EEG in patients with major depressive disorders (MDD). Eur. Neuropsychopharmacol., 2005, 15(Suppl. 3), 435
    • (2005) Eur. Neuropsychopharmacol , vol.15 , Issue.1 SUPPL. , pp. 435
    • Quera-Salva, M.A.1    Vanier, B.2    Chapotot, F.3
  • 100
    • 33845509861 scopus 로고    scopus 로고
    • Cycling alternating pattern, in the NREM sleep of patients within major depressive disorder: Baseline results, and change overtime with a new antidepressant
    • Lopes, M.C.; Quera-Salva, M.A.; Guilleminault, C. Cycling alternating pattern, in the NREM sleep of patients within major depressive disorder: baseline results, and change overtime with a new antidepressant. Sleep Med., 2005, 6(Suppl 2), 87
    • (2005) Sleep Med , vol.6 , Issue.1 SUPPL. , pp. 87
    • Lopes, M.C.1    Quera-Salva, M.A.2    Guilleminault, C.3
  • 101
    • 67650594924 scopus 로고    scopus 로고
    • Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine
    • Pandi-Perumal, S.R.; Moscovitch, A.; Srinivasan, V.; Spence, D.W.; Cardinali, D.P.; Brown, G.M. Bidirectional communication between sleep and circadian rhythms and its implications for depression: lessons from agomelatine. Prog. Neurobiol., 2009, 88, 264-271
    • (2009) Prog. Neurobiol , vol.88 , pp. 264-271
    • Pandi-Perumal, S.R.1    Moscovitch, A.2    Srinivasan, V.3    Spence, D.W.4    Cardinali, D.P.5    Brown, G.M.6
  • 102
    • 0026588221 scopus 로고
    • Combined effects of diazepam and melatonin in two tests for anxiolytic activity in the mouse
    • Guardiola-Lemaitre, B.; Lenegre, A.; Porsolt, R.D. Combined effects of diazepam and melatonin in two tests for anxiolytic activity in the mouse. Pharmacol. Biochem. Behav., 1992, 41, 405-408
    • (1992) Pharmacol. Biochem. Behav , vol.41 , pp. 405-408
    • Guardiola-Lemaitre, B.1    Lenegre, A.2    Porsolt, R.D.3
  • 103
    • 0033046212 scopus 로고    scopus 로고
    • The effects of melatonin on the behavioural disturbances induced by chronic mild stress in C3H/He mice
    • Kopp, C.; Vogel, E.; Rettori, M. C.; Delagrange, P.; Misslin, R. The effects of melatonin on the behavioural disturbances induced by chronic mild stress in C3H/He mice. Behav. Pharmacol., 1999, 10, 73-83
    • (1999) Behav. Pharmacol , vol.10 , pp. 73-83
    • Kopp, C.1    Vogel, E.2    Rettori, M.C.3    Delagrange, P.4    Misslin, R.5
  • 104
    • 0034097926 scopus 로고    scopus 로고
    • Anxiolytic-like properties of melatonin receptor agonists in mice: Involvement of MT1 and/or MT2 receptors in the regulation of emotional responsiveness
    • Kopp, C.; Vogel, E.; Rettori, M.C.; Delagrange, P.; Misslin, R. Anxiolytic-like properties of melatonin receptor agonists in mice: involvement of MT1 and/or MT2 receptors in the regulation of emotional responsiveness. Neuropharmacology, 2000, 39, 1865-1871
    • (2000) Neuropharmacology , vol.39 , pp. 1865-1871
    • Kopp, C.1    Vogel, E.2    Rettori, M.C.3    Delagrange, P.4    Misslin, R.5
  • 105
    • 0035815551 scopus 로고    scopus 로고
    • Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat
    • Kennaway, D.J.; Moyer, R.W.; Voultsios, A.; Varcoe, T.J. Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat. Brain Res., 2001, 897, 36-43
    • (2001) Brain Res , vol.897 , pp. 36-43
    • Kennaway, D.J.1    Moyer, R.W.2    Voultsios, A.3    Varcoe, T.J.4
  • 106
    • 0032576022 scopus 로고    scopus 로고
    • Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms
    • Kennaway, D.J.; Moyer, R.W. Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms. Brain Res., 1998, 806, 257-270
    • (1998) Brain Res , vol.806 , pp. 257-270
    • Kennaway, D.J.1    Moyer, R.W.2
  • 107
    • 0036175640 scopus 로고    scopus 로고
    • Dissociable hormonal, cognitive and mood responses to neuroendocrine challenge: Evidence for receptor-specific serotonergic dysregulation in depressed mood
    • Riedel, W.J.; Klaassen, T.; Griez, E.; Honig, A.; Menheere, P.P.C.A.; Van Praag, H.M. Dissociable hormonal, cognitive and mood responses to neuroendocrine challenge: evidence for receptor-specific serotonergic dysregulation in depressed mood. Neuropsychopharmacology, 2002, 26, 358-367
    • (2002) Neuropsychopharmacology , vol.26 , pp. 358-367
    • Riedel, W.J.1    Klaassen, T.2    Griez, E.3    Honig, A.4    Menheere, P.P.C.A.5    van Praag, H.M.6
  • 108
    • 33751003505 scopus 로고    scopus 로고
    • Drug and region-specific effects of protracted antidepressant and cocaine treatment on the content of melatonin MT1 and MT2 receptor mRNA in the mouse brain
    • Imbesi, M.; Uz, T.; Yildiz, S.; Arslan, A.D.; Manev, H. Drug and region-specific effects of protracted antidepressant and cocaine treatment on the content of melatonin MT1 and MT2 receptor mRNA in the mouse brain. Int. J. Neuroprot. Neuroregener., 2006, 2, 185-189
    • (2006) Int. J. Neuroprot. Neuroregener , vol.2 , pp. 185-189
    • Imbesi, M.1    Uz, T.2    Yildiz, S.3    Arslan, A.D.4    Manev, H.5
  • 110
    • 0036738228 scopus 로고    scopus 로고
    • Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: A placebo-controlled dose range study
    • Loo, H.; Hale, A.; D'Haenen, H. Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study. Int. Clin. Psychopharmacol., 2002, 17, 239-247
    • (2002) Int. Clin. Psychopharmacol , vol.17 , pp. 239-247
    • Loo, H.1    Hale, A.2    D'Haenen, H.3
  • 111
    • 0030218832 scopus 로고    scopus 로고
    • Entrainment of circadian rhythms by S 20098, a melatonin agonist, is dose and plasma concentration dependent
    • Martinet, L.; Guardiola-Lemaitre, B.; Mocaer, E. Entrainment of circadian rhythms by S 20098, a melatonin agonist, is dose and plasma concentration dependent. Pharmacol. Biochem. Behav., 1996, 54, 713-718
    • (1996) Pharmacol. Biochem. Behav , vol.54 , pp. 713-718
    • Martinet, L.1    Guardiola-Lemaitre, B.2    Mocaer, E.3
  • 113
    • 33646686569 scopus 로고    scopus 로고
    • Efficacy and tolerance profile of agomelatine and practical use in depressed patients
    • Rouillon, F. Efficacy and tolerance profile of agomelatine and practical use in depressed patients. Int. Clin. Psychopharmacol., 2006, 21(Suppl 1), 31-35
    • (2006) Int. Clin. Psychopharmacol , vol.21 , Issue.1 SUPPL. , pp. 31-35
    • Rouillon, F.1
  • 114
    • 33749515230 scopus 로고    scopus 로고
    • Major depressive disorders: Clinical efficacy and tolerability of agomelatine, a new melatonergic agonist
    • Montgomery, S.A. Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist. Eur. Neuropsychopharmacol., 2006, 16, 633-638
    • (2006) Eur. Neuropsychopharmacol , vol.16 , pp. 633-638
    • Montgomery, S.A.1
  • 115
    • 31344471423 scopus 로고    scopus 로고
    • Placebo-controlled trial of agomelatine in the treatment of major depressive disorder
    • Kennedy, S.H.; Emsley, R. Placebo-controlled trial of agomelatine in the treatment of major depressive disorder. Eur. Neuropsychopharmacol., 2006, 16, 93-100
    • (2006) Eur. Neuropsychopharmacol , vol.16 , pp. 93-100
    • Kennedy, S.H.1    Emsley, R.2
  • 116
    • 37049039648 scopus 로고    scopus 로고
    • Improvement in subjective sleep in major depressive disorder with a novel antidepressant, agomelatine: Randomized, double-blind comparison with venlafaxine
    • Lemoine, P.; Guilleminault, C.; Alvarez, E. Improvement in subjective sleep in major depressive disorder with a novel antidepressant, agomelatine: randomized, double-blind comparison with venlafaxine. J. Clin. Psychiatry, 2007, 68, 1723-1732
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 1723-1732
    • Lemoine, P.1    Guilleminault, C.2    Alvarez, E.3
  • 117
    • 51449112441 scopus 로고    scopus 로고
    • A double-blind comparison of sexual functioning, antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR
    • Kennedy, S.H.; Rizvi, S.; Fulton, K.; Rasmussen, J. A double-blind comparison of sexual functioning, antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR. J. Clin. Psychopharmacol., 2008, 28, 329-333
    • (2008) J. Clin. Psychopharmacol , vol.28 , pp. 329-333
    • Kennedy, S.H.1    Rizvi, S.2    Fulton, K.3    Rasmussen, J.4
  • 118
    • 4344715163 scopus 로고    scopus 로고
    • Absence of discontinuation symptoms with agomelatine and occurrence of discontinuation symptoms with paroxetine: A randomized, double- blind, placebo-controlled discontinuation study
    • Montgomery, S.A.; Kennedy, S.H.; Burrows, G.D.; Lejoyeux, M.; Hindmarch, I. Absence of discontinuation symptoms with agomelatine and occurrence of discontinuation symptoms with paroxetine: a randomized, double- blind, placebo-controlled discontinuation study. Int. Clin. Psychopharmacol., 2004, 19, 271-280
    • (2004) Int. Clin. Psychopharmacol , vol.19 , pp. 271-280
    • Montgomery, S.A.1    Kennedy, S.H.2    Burrows, G.D.3    Lejoyeux, M.4    Hindmarch, I.5
  • 120
    • 34548446414 scopus 로고    scopus 로고
    • Agomelatine adjunctive therapy for acute bipolar depression: Preliminary open data
    • Calabrese, J.R.; Guelfi, J.D.; Perdrizet-Chevallier, C. Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data. Bipolar Disord., 2007, 9, 628-635
    • (2007) Bipolar Disord , vol.9 , pp. 628-635
    • Calabrese, J.R.1    Guelfi, J.D.2    Perdrizet-Chevallier, C.3
  • 121
    • 70449730247 scopus 로고    scopus 로고
    • Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults
    • Howland, R.H. Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults. Neuropsychiatr. Dis. Treat., 2009, 5, 563-576
    • (2009) Neuropsychiatr. Dis. Treat , vol.5 , pp. 563-576
    • Howland, R.H.1
  • 122
    • 33749684662 scopus 로고    scopus 로고
    • Pharmacological profile of antidepressants: A likely basis for their efficacy and side effects
    • Hamon, M.; Bourgoin, S. Pharmacological profile of antidepressants: a likely basis for their efficacy and side effects? Eur. Neuropsychopharmacol., 2006, 16, 625-632
    • (2006) Eur. Neuropsychopharmacol , vol.16 , pp. 625-632
    • Hamon, M.1    Bourgoin, S.2
  • 123
    • 18644386303 scopus 로고    scopus 로고
    • Antidepressants and sleep. A qualitative review of the literature
    • Wilson, S. Antidepressants and sleep. A qualitative review of the literature. Drugs, 2005, 65, 927-947
    • (2005) Drugs , vol.65 , pp. 927-947
    • Wilson, S.1
  • 124
    • 33749673149 scopus 로고    scopus 로고
    • Melatonin and S-20098 improve sleep disorder and life expectancy in an animal model of sleeping sickness
    • Mechanisms and Applications; Touitou, Y., Ed.; Elsevier Science: Amsterdam
    • Grassi-Zucconi, G.; Semprevivo, M.; Carandente, F.; Mocaer, E.; Kristensson, K.; Bentivoglio, M. Melatonin and S-20098 improve sleep disorder and life expectancy in an animal model of sleeping sickness. In: Biological Clocks. Mechanisms and Applications; Touitou, Y., Ed.; Elsevier Science: Amsterdam, 1998, pp. 305-308
    • (1998) Biological Clocks , pp. 305-308
    • Grassi-Zucconi, G.1    Semprevivo, M.2    Carandente, F.3    Mocaer, E.4    Kristensson, K.5    Bentivoglio, M.6
  • 125
    • 33646689322 scopus 로고    scopus 로고
    • Sleep disturbances and depression: A challenge for antidepressants
    • Lam, R.W. Sleep disturbances and depression: a challenge for antidepressants. Int. Clin. Psychopharmacol., 2006, 21, 25-29
    • (2006) Int. Clin. Psychopharmacol , vol.21 , pp. 25-29
    • Lam, R.W.1
  • 127
    • 33646672157 scopus 로고    scopus 로고
    • Pharmacology of a new antidepressant: Benefit of the implication of the melatonergic system
    • Fuchsa, E.; Simon, M.; Schmelting, B. Pharmacology of a new antidepressant: benefit of the implication of the melatonergic system. Int. Clin. Psychopharmacol., 2006, 21, 17-20
    • (2006) Int. Clin. Psychopharmacol , vol.21 , pp. 17-20
    • Fuchsa, E.1    Simon, M.2    Schmelting, B.3
  • 129
    • 34547781887 scopus 로고    scopus 로고
    • Severe depression and antidepressants: Focus on a pooled analysis of placebo-controlled studies on agomelatine
    • Montgomery, S.A.; Kasper, S. Severe depression and antidepressants: focus on a pooled analysis of placebo-controlled studies on agomelatine. Int. Clin. Psychopharmacol., 2007, 22, 283-291
    • (2007) Int. Clin. Psychopharmacol , vol.22 , pp. 283-291
    • Montgomery, S.A.1    Kasper, S.2
  • 131
    • 70449835855 scopus 로고    scopus 로고
    • Agomelatine, an innovative pharmacological response to unmet needs
    • Le Strat, Y.; Gorwood, P. Agomelatine, an innovative pharmacological response to unmet needs. J. Psychopharmacol., 2008, 22, 4-8
    • (2008) J. Psychopharmacol , vol.22 , pp. 4-8
    • Le, S.Y.1    Gorwood, P.2
  • 132
    • 0034044051 scopus 로고    scopus 로고
    • Reciprocal autoreceptor and heteroreceptor control of serotonergic dopaminergic and noradrenergic transmission in the frontal cortex: Relevance to the actions of antidepressant agents
    • Millan, M.J.; Lejeune, F.; Gobert, A. Reciprocal autoreceptor and heteroreceptor control of serotonergic dopaminergic and noradrenergic transmission in the frontal cortex: relevance to the actions of antidepressant agents. J. Psychopharmacol., 2008, 14, 114-138
    • (2008) J. Psychopharmacol , vol.14 , pp. 114-138
    • Millan, M.J.1    Lejeune, F.2    Gobert, A.3
  • 133
    • 67650642499 scopus 로고    scopus 로고
    • Melatonin receptor agonist agomelatine: A new drug for treating unipolar depression
    • Bourin, M.; Prica, C. Melatonin receptor agonist agomelatine: a new drug for treating unipolar depression. Curr. Pharm. Des., 2009, 15, 1675-1682
    • (2009) Curr. Pharm. Des , vol.15 , pp. 1675-1682
    • Bourin, M.1    Prica, C.2
  • 134
    • 2342459611 scopus 로고    scopus 로고
    • Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: Involvement of melatonin and serotonin receptors
    • Bourin, M.; Mocaer, E.; Porsolt, R. Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: Involvement of melatonin and serotonin receptors. J. Psychiatry Neurosci., 2004, 29, 126-133
    • (2004) J. Psychiatry Neurosci , vol.29 , pp. 126-133
    • Bourin, M.1    Mocaer, E.2    Porsolt, R.3
  • 135
    • 44249109659 scopus 로고    scopus 로고
    • Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity
    • Gressens, P.; Schwendimann, L.; Husson, I.; Sarkozy, G.; Mocaer, E.; Vamecq, J.; Spedding, M. Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity. Eur. J. Pharmacol., 2008, 588, 58-63
    • (2008) Eur. J. Pharmacol , vol.588 , pp. 58-63
    • Gressens, P.1    Schwendimann, L.2    Husson, I.3    Sarkozy, G.4    Mocaer, E.5    Vamecq, J.6    Spedding, M.7
  • 136
    • 33744919791 scopus 로고    scopus 로고
    • Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis
    • Banasr, M.; Soumier, A.; Hery, M.; Mocaer, E.; Daszuta, A. Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol. Psychiatry, 2006, 59, 1087-1096
    • (2006) Biol. Psychiatry , vol.59 , pp. 1087-1096
    • Banasr, M.1    Soumier, A.2    Hery, M.3    Mocaer, E.4    Daszuta, A.5
  • 137
    • 5044229846 scopus 로고    scopus 로고
    • Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat
    • Kodama, M.; Fujioka, T.; Duman, R.S. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol. Psychiatry, 2004, 56, 570-580
    • (2004) Biol. Psychiatry , vol.56 , pp. 570-580
    • Kodama, M.1    Fujioka, T.2    Duman, R.S.3
  • 138
    • 77649107717 scopus 로고    scopus 로고
    • Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration
    • Molteni
    • Molteni, R.; Calabrese, F.; Pisoni, S.; Gabriel, C.; Mocaer, E.; Racagni, G.; Riva, M.A. Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration. World J. Biol. Psychiatry, 2010, 11, 148-153
    • (2010) World J. Biol. Psychiatry , vol.11 , pp. 148-153
    • Molteni, R.1    Calabrese, F.2    Pisoni, S.3    Gabriel, C.4    Mocaer, E.5    Racagni, G.6    Riva, M.A.7
  • 139
    • 34948841405 scopus 로고    scopus 로고
    • Efficacy of agomelatine, a MT1/MT2 receptor agonist with 5-HT2C antagonistic properties, in major depressive disorder
    • Olie, J.P.; Kasper, S. Efficacy of agomelatine, a MT1/MT2 receptor agonist with 5-HT2C antagonistic properties, in major depressive disorder. Int. J. Neuropsychopharmacol., 2007, 10, 661-673
    • (2007) Int. J. Neuropsychopharmacol , vol.10 , pp. 661-673
    • Olie, J.P.1    Kasper, S.2
  • 140
    • 77649107286 scopus 로고    scopus 로고
    • Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: A randomized, double-blind comparison with sertraline
    • Kasper, S.; Hajak, G.; Wulff, K.; Hoogendijk, W.J.; Montejo, A.L.; Smeraldi, E.; Rybakowski, J.K.; Quera-Salva, M.A.; Wirz-Justice, A.M.; Picarel-Blanchot, F.; Baylé, F.J. Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: a randomized, double-blind comparison with sertraline. J. Clin. Psychiatry, 2010, 71, 109-120
    • (2010) J. Clin. Psychiatry , vol.71 , pp. 109-120
    • Kasper, S.1    Hajak, G.2    Wulff, K.3    Hoogendijk, W.J.4    Montejo, A.L.5    Smeraldi, E.6    Rybakowski, J.K.7    Quera-Salva, M.A.8    Wirz-Justice, A.M.9    Picarel-Blanchot, F.10    Baylé, F.J.11
  • 142
    • 77952156000 scopus 로고    scopus 로고
    • Efficacy and safety of agomelatine in the treatment of major depressive disorder. a multicenter, randomized, double-blind, placebo-controlled trial
    • Zajecka, J.; Schatzberg, A.; Stahl, S.M.; Shah, A.; Caputo, A.; Post, A. Efficacy and safety of agomelatine in the treatment of major depressive disorder. a multicenter, randomized, double-blind, placebo-controlled trial. J. Clin. Psychopharmacol., 2010, 30, 135-144
    • (2010) J. Clin. Psychopharmacol , vol.30 , pp. 135-144
    • Zajecka, J.1    Schatzberg, A.2    Stahl, S.M.3    Shah, A.4    Caputo, A.5    Post, A.6
  • 143
    • 77952646342 scopus 로고    scopus 로고
    • Agomelatine in the treatment of major depressive disorder: An 8- week, multicenter, randomized, placebo-controlled trial
    • Stahl, S.M.; Fava, M.; Trivedi, M.H.; Caputo, A.; Shah, A.; Post, A. Agomelatine in the treatment of major depressive disorder: an 8- week, multicenter, randomized, placebo-controlled trial. J. Clin. Psychiatry, 2010, 71(5), 616-626
    • (2010) J. Clin. Psychiatry , vol.71 , Issue.5 , pp. 616-626
    • Stahl, S.M.1    Fava, M.2    Trivedi, M.H.3    Caputo, A.4    Shah, A.5    Post, A.6
  • 144
    • 70349570733 scopus 로고    scopus 로고
    • Agomelatine prevents relapse in patients with major depressive disorder without evidence of a discontinuation syndrome: A 24-week randomized, double-blind, placebo-controlled trial
    • Goodwin, Agomelatine Study Group
    • Goodwin, G.M.; Emsley, R.; Rembry, S.; Rouillon, F.; Agomelatine Study Group. Agomelatine prevents relapse in patients with major depressive disorder without evidence of a discontinuation syndrome: a 24-week randomized, double-blind, placebo-controlled trial. J. Clin. Psychiatry, 2009, 70, 1128-1137
    • (2009) J. Clin. Psychiatry , vol.70 , pp. 1128-1137
    • Goodwin, G.M.1    Emsley, R.2    Rembry, S.3    Rouillon, F.4
  • 145
    • 84969752458 scopus 로고    scopus 로고
    • National Institutes of Health [Accessed April 8, 2010
    • National Institutes of Health. ClinicalTrials.gov. Search for clinical trials. http://www.clinicaltrials.gov/ct2/results?term=agomelatine [Accessed April 8, 2010]
    • ClinicalTrials.gov. Search For Clinical Trials
  • 147
    • 36549050728 scopus 로고    scopus 로고
    • Non-REM sleep instability in patients with major depressive disorder: Subjective improvement and improvement of non-REM sleep instability with treatment (agomelatine)
    • Lopes, M.C.; Quera-Salva, M.A.; Guilleminault, C. Non-REM sleep instability in patients with major depressive disorder: subjective improvement and improvement of non-REM sleep instability with treatment (agomelatine). Sleep Med., 2007, 9, 33-41
    • (2007) Sleep Med , vol.9 , pp. 33-41
    • Lopes, M.C.1    Quera-Salva, M.A.2    Guilleminault, C.3
  • 149
    • 58149129754 scopus 로고    scopus 로고
    • Efficacy of agomelatine in generalized anxiety disorder: A randomized, double-blind, placebo-controlled study
    • Stein, D.J.; Ahokas, A.A.; de Bodinat, C. Efficacy of agomelatine in generalized anxiety disorder: A randomized, double-blind, placebo-controlled study. J. Clin. Psychopharmacol., 2008, 28, 561-566
    • (2008) J. Clin. Psychopharmacol , vol.28 , pp. 561-566
    • Stein, D.J.1    Ahokas, A.A.2    de Bodinat, C.3
  • 150
    • 77956202090 scopus 로고    scopus 로고
    • Agomelatine in the treatment of mood and anxiety disorders
    • Baldwin, D.S.; Lopes, A.T. Agomelatine in the treatment of mood and anxiety disorders. Br. J. Hosp. Med., 2010, 71, 153-156
    • (2010) Br. J. Hosp. Med , vol.71 , pp. 153-156
    • Baldwin, D.S.1    Lopes, A.T.2
  • 152
    • 70350717700 scopus 로고    scopus 로고
    • Agomelatine: Innovative pharmacological approach in depression
    • Popoli, M. Agomelatine: innovative pharmacological approach in depression. CNS Drugs, 2009, 23(Suppl 2), 27-34
    • (2009) CNS Drugs , vol.23 , Issue.1 SUPPL. , pp. 27-34
    • Popoli, M.1
  • 153
    • 70350706600 scopus 로고    scopus 로고
    • Agomelatine: Efficacy at each phase of antidepressant treatment
    • Kennedy, S.H. Agomelatine: efficacy at each phase of antidepressant treatment. CNS Drugs, 2009, 23(Suppl 2), 41-47.
    • (2009) CNS Drugs , vol.23 , Issue.1 SUPPL. , pp. 41-47
    • Kennedy, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.