Polymorphisms in the endothelin-1 and endothelin A receptor genes and survival in patients with locoregionally advanced nasopharyngeal carcinoma

Clinical Cancer Research

Volumn 17, Issue 8, 2011, Pages 2451-2458

  Wen, Yue Feng ^a,b   Qi, Bin ^a,b   Liu, Huai ^a,b   Mo, Hao Yuan ^a,b   Chen, Qiu Yan ^a,b   Li, Juan ^a,b   Huang, Pei Yu ^a,b   Ye, Yan Fang ^a,b   Zhang, Ying ^a,b   Deng, Man Quan ^a,b   Guo, Xiang ^a,b   Hong, Ming Huang ^a,b   Cao, Ka Jia ^a,b   Mai, Hai Qiang ^a,b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; FLUOROURACIL;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CHEMORADIOTHERAPY; CONTROLLED STUDY; ENDOTHELIN 1 GENE; ENDOTHELIN A RECEPTOR GENE; FEMALE; GENE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MEGAVOLTAGE RADIOTHERAPY; MULTIPLE CYCLE TREATMENT; NASOPHARYNX CARCINOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; REPEATED DRUG DOSE; WILD TYPE;

ADOLESCENT; ADULT; AGED; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOTHELIN-1; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NASOPHARYNGEAL NEOPLASMS; OUTCOME ASSESSMENT (HEALTH CARE); POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECEPTOR, ENDOTHELIN A; RISK FACTORS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 79954613624     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-10-2264     Document Type: Article

References (48)

1. Min HQ. Nasopharyngeal carcinoma. In: Gun GY, editor. Epidemiology. Beijing, China: People's Medical Press; 1996. p. 280-5.
2. Altun M, Fandi A, Dupuis O, Cvitkovic E, Krajina Z, Eschwege F. Undifferentiated nasopharyngeal cancer (UCNT): current diagnostic and therapeutic aspects. Int J Radiat Oncol Biol Phys 1995;32:859-77.
3. Huncharek M, Kupelnick B. Combined chemoradiation versus radiation therapy alone in locally advanced nasopharyngeal carcinoma: results of a meta-analysis of 1, 528 patients from six randomized trials. Am J Clin Oncol 2002;25:219-23. (Pubitemid 34602538)
4. Langendijk JA, Leemans CR, Buter J, Berkhof J, Slotman BJ. The additional value of chemotherapy to radiotherapy in locally advanced nasopharyngeal carcinoma: a meta-analysis of the published literature. J Clin Oncol 2004;22:4604-12. (Pubitemid 41185128)
5. Grant K, Loizidou M, Taylor I. Endothelin-1: a multifunctional molecule in cancer. Br J Cancer 2003;88:163-6.
6. Nelson J, Bagnato A, Battistini B, Nisen P. The endothelin axis: emerging role in cancer. Nat Rev Cancer 2003;3:110-6. (Pubitemid 37328878)
7. Grant K, Knowles J, Dawas K, Burnstock G, Taylor I, Loizidou M. Mechanisms of endothelin 1-stimulated proliferation in colorectal cancer cell lines. Br J Surg 2007;94:106-12. (Pubitemid 46142740)
8. Zhang WM, Zhou J, Ye QJ. Endothelin-1 enhances proliferation of lung cancer cells by increasing intracellular free Ca2+. Life Sci 2008;82:764-71.
9. Wülfing P, Kersting C, Tio J, Fischer RJ, Wülfing C, Poremba C, et al. Endothelin-1-, endothelin-A-, and endothelin-B-receptor expression is correlated with vascular endothelial growth factor expression and angiogenesis in breast cancer. Clin Cancer Res 2004;10:2393-400. (Pubitemid 38445698)
10. Knowles J, Loizidou M, Taylor I. Endothelin-1 and angiogenesis in cancer. Curr Vasc Pharmacol 2005;3:309-14. (Pubitemid 41264282)
11. Wilson JL, Burchell J, Grimshaw MJ. Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1. Cancer Res 2006;66:11802-7. (Pubitemid 46094191)
12. Rosanò L, Cianfrocca R, Masi S, Spinella F, Di Castro V, Biroccio A, et al. Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci U S A 2009;106:2806-11.
13. Nelson JB, Udan MS, Guruli G, Pflug BR. Endothelin-1 inhibits apoptosis in prostate cancer. Neoplasia 2005;7:631-7. (Pubitemid 41099416)
14. Del Bufalo D, Di Castro V, Biroccio A, Varmi M, Salani D, Rosanò L, et al. Endothelin-1 protects ovarian carcinoma cells against paclitaxelinduced apoptosis: requirement for Akt activation. Mol Pharmacol 2002;61:524-32. (Pubitemid 34171918)
15. Mai HQ, Zeng ZY, Zhang CQ, Feng KT, Guo X, Mo HY, et al. Elevated plasma big ET-1 is associated with distant failure in patients with advanced-stage nasopharyngeal carcinoma. Cancer 2006;106:1548-53.
16. Mai HQ, Zeng ZY, Zhang HZ, Hou JH, Mo HY, Guo X, et al. Correlation of endothelin A receptor expression to prognosis of nasopharyngeal carcinoma. Chin J Cancer 2005;24:611-5.
17. Mai HQ, Zeng ZY, Feng KT, Ye YL, Zhang CQ, Liang WJ, et al. Therapeutic targeting of the endothelin a receptor in human nasopharyngeal carcinoma. Cancer Sci 2006;97:1388-95.
18. Kim SH, Kim JY, Kim DM, Ko HS, Kim SY, Yoo T, et al. Investigations on the association between normal tension glaucoma and single nucleotide polymorphisms of the endothelin-1 and endothelin receptor genes. Mol Vis 2006;12:1016-21. (Pubitemid 44309183)
19. Colombo MG, Ciofini E, Paradossi U, Bevilacqua S, Biagini A. ET-1 Lys198Asn and ET (A) receptor H323H polymorphisms in heart failure. A case-control study. Cardiology 2006;105:246-52. (Pubitemid 43725780)
20. Herrmann S, Schmidt-Petersen K, Pfeifer J, Perrot A, Bit-Avragim N, Eichhorn C, et al. A polymorphism in the endothelin-A receptor gene predicts survival in patients with idiopathic dilated cardiomyopathy. Eur Heart J 2001;22:1948-53. (Pubitemid 33054675)
21. Telgmann R, Harb BA, Ozcelik C, Perrot A, Schönfelder J, Nonnenmacher A, et al. The G-231A polymorphism in the endothelin-A receptor gene is associated with lower aortic pressure in patients with dilated cardiomyopathy. Am J Hypertens 2007;20:32-7. (Pubitemid 46014068)
22. Li H, Louey JW, Choy KW, Liu DT, Chan WM, Chan YM, et al. EDN1 Lys198Asn is associated with diabetic retinopathy in type 2 diabetes. Mol Vis 2008;14:1698-704.
23. Yasuda H, Kamide K, Takiuchi S, Matayoshi T, Hanada H, Kada A, et al. Association of single nucleotide polymorphisms in endothelin family genes with the progression of atherosclerosis in patients with essential hypertension. J Hum Hypertens 2007;21:883-92. (Pubitemid 350020340)
24. Fleming ID, Cooper JS, Henson DE, et al. editors. AJCC Cancer Staging Manual. 5th ed. Philadelphia: Lippincott-Raven; 1997. p. 31-9.
25. Sobin LH, Wittekind C, editors. UICC TNM Classification of Malignant Tumours. 5th ed. New York: Wiley-Liss; 1997. p. 26-30.
26. Shanmugaratnam K, Sobin LH, editors. World Health Organization. International Histological Classification: Histological Typing of Tumors of the Upper Respiratory Tract and Ear. 2nd ed. Berlin, Germany: Springer-Verlag; 1991.
27. Ma J, Mai HQ, Hong MH, Cui NJ, Lu TX, Lu LX, et al. Is the 1997 AJCC staging system for nasopharyngeal carcinoma prognostically useful for Chinese patient populations? Int J Radiat Oncol Biol Phys 2001;50:1181-9. (Pubitemid 32727794)
28. Khanna M, Cao W, Zirvi M, Paty P, Barany F. Ligase detection reaction for identification of low abundance mutations. Clin Biochem 1999;32:287-90. (Pubitemid 29385661)
29. Consolandi C, Busti E, Pera C, Delfino L, Ferrara GB, Bordoni R, et al. Detection of HLA polymorphisms by ligase detection reaction and a universal array format: a pilot study for low resolution genotyping. Hum Immunol 2003;64:168-78. (Pubitemid 36109826)
30. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63. (Pubitemid 14203433)
31. Shi YY, He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 2005;15:97-8. (Pubitemid 41653949)
32. Fallin D, Cohen A, Essioux L, Chumakov I, Blumenfeld M, Cohen D, et al. Genetic analysis of case/control data using estimated haplotype frequencies: application to APOE locus variation and Alzheimer's disease. Genome Res 2001;11:143-51. (Pubitemid 32117960)
33. Graziano F, Ruzzo A, Santini D, Humar B, Tonini G, Catalano V, et al. Prognostic role of interleukin-1beta gene and interleukin-1 receptor antagonist gene polymorphisms in patients with advanced gastric cancer. J Clin Oncol 2005;23:2339-45. (Pubitemid 46218727)
34. Moore SW, Zaahl MG. Association of endothelin-beta receptor (EDNRB) gene variants in anorectal malformations. J Pediatr Surg 2007;42:1266-70. (Pubitemid 47017302)
35. Kim JH, Yoon KO, Kim H, Kim JK, Kim JW, Lee SK, et al. New variations of the EDNRB gene and its association with sporadic Hirschsprung's disease in Korea. J Pediatr Surg 2006;41:1708-12. (Pubitemid 44441375)
36. Taillé C, Guénégou A, Almolki A, Piperaud M, Leynaert B, Vuillaumier S, et al. ETB receptor polymorphism is associated with airway obstruction. BMC Pulm Med 2007;7:5.
37. Lo KW, Tsang YS, Kwong J, To KF, Teo PM, Huang DP. Promoter hypermethylation of the EDNRB gene in nasopharyngeal carcinoma. Int J Cancer 2002;98:651-5. (Pubitemid 34225614)
38. Zhou L, Feng X, Shan W, Zhou W, Liu W, Wang L, et al. Epigenetic and genetic alterations of the EDNRB gene in nasopharyngeal carcinoma. Oncology 2007;72:357-63. (Pubitemid 351238150)
39. Komar AA. Silent SNPs: impact on gene function and phenotype. Pharmacogenomics 2007;8:1075-80. (Pubitemid 47423694)
40. Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmöller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A 2000;97:3473-8. (Pubitemid 30183327)
41. Kimchi-Sarfaty C, Oh JM, Kim IW, Sauna ZE, Calcagno AM, Ambudkar SV, et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 2007;315:525-8. (Pubitemid 46175758)
42. Barden AE, Herbison CE, Beilin LJ, Michael CA, Walters BN, Van Bockxmeer FM. Association between the endothelin-1 gene Lys198Asn polymorphism blood pressure and plasma endothelin-1 levels in normal and pre-eclamptic pregnancy. J Hypertens 2001;19:1775-82. (Pubitemid 32924943)
43. Bagnato A, Rosano L. The endothelin axis in cancer. Int J Biochem Cell Biol 2008;40:1443-51.
44. Wülfing P, Tio J, Kersting C, Sonntag B, Buerger H, Wülfing C, et al. Expression of endothelin-A-receptor predicts unfavourable response to neoadjuvant chemotherapy in locally advanced breast cancer. Br J Cancer 2004;91:434-40. (Pubitemid 39093560)
45. Sonveaux P, Dessy C, Martinive P, Havaux X, Jordan BF, Gallez B, et al. Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment. Cancer Res 2004;64:3209-14. (Pubitemid 38581424)
46. Yang KM, Russell J, Lupu ME, Cho H, Li XF, Koutcher JA, et al. Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model. Cancer Biol Ther 2009;8:1940-6.
47. Carducci MA, Padley RJ, Breul J, Vogelzang NJ, Zonnenberg BA, Daliani DD, et al. Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. J Clin Oncol 2003;21:679-89. (Pubitemid 46621903)
48. Nelson JB, Love W, Chin JL, Saad F, Schulman CC, Sleep DJ, et al. Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008;113:2478-87.