Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow

Life Sciences

Volumn 88, Issue 17-18, 2011, Pages 753-760

  Erdem, Ş Remzi ^a   Emre Aydingöz, Selda ^b   Atilla, Pergin ^c   Çakar, A Nur ^c   Dalkara, Turgay ^c   Bolay, Hayrunnisa ^d   Tuncer, Meral ^a  

^a BASKENT UNIVERSITY   (Turkey)

^b Edita Medical Writing and Editing ^*  (Turkey)

^c HACETTEPE UNIVERSITY   (Turkey)

^d GAZI UNIVERSITY   (Turkey)

Author keywords

Cyclosporine A; Endothelin; Guinea pigs; Hepatotoxicity; Laser Doppler flowmeter

Indexed keywords

BOSENTAN; CREMOPHOR; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); CYCLOSPORIN A; ENDOTHELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE REDUCTION; GUINEA PIG; HEMODYNAMICS; HISTOPATHOLOGY; IN VIVO STUDY; LIVER BLOOD FLOW; LIVER TOXICITY; MEAN ARTERIAL PRESSURE; NONHUMAN;

ANIMALS; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELINS; FEMALE; GLYCEROL; GUINEA PIGS; LIVER; LIVER CIRCULATION; MALE; PEPTIDES, CYCLIC; SULFONAMIDES;

ANIMALIA; CAVIA;

EID: 79954609807     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.02.015     Document Type: Article

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