메뉴 건너뛰기




Volumn 63, Issue 11, 1997, Pages 1574-1578

Cholestatic effects of cyclosporine in the rat

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BILE SALT; BILIRUBIN; CHOLESTEROL; CREMOPHOR; CYCLOSPORIN A; PHOSPHOLIPID; SODIUM CHLORIDE;

EID: 0031007210     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199706150-00006     Document Type: Article
Times cited : (34)

References (38)
  • 1
    • 0027170712 scopus 로고
    • Cyclosporin: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders
    • Faulds D, Gao KL, Benfield P. Cyclosporin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs 1993; 45: 953.
    • (1993) Drugs , vol.45 , pp. 953
    • Faulds, D.1    Gao, K.L.2    Benfield, P.3
  • 2
    • 0016756836 scopus 로고
    • Bile composition and bile cast formation after transplantation of the liver in man
    • Waldram R, Williams R, Calne RY. Bile composition and bile cast formation after transplantation of the liver in man. Transplantation 1975; 19: 382.
    • (1975) Transplantation , vol.19 , pp. 382
    • Waldram, R.1    Williams, R.2    Calne, R.Y.3
  • 3
    • 0025991962 scopus 로고
    • Bile compositional changes and cholesterol stone formation following orthotopic liver transplantation
    • Farouk M, Branum GD, Watters CR, et al. Bile compositional changes and cholesterol stone formation following orthotopic liver transplantation. Transplantation 1991; 52: 727.
    • (1991) Transplantation , vol.52 , pp. 727
    • Farouk, M.1    Branum, G.D.2    Watters, C.R.3
  • 4
    • 0023103679 scopus 로고
    • Complications of cyclosporine-prednisone immunosuppression in 402 renal transplant recipients exclusively followed by a single center from one to five years
    • Kahn BD, Flechner SM, Lorber MI, Golden D, Conley S, Van Buren CT. Complications of cyclosporine-prednisone immunosuppression in 402 renal transplant recipients exclusively followed by a single center from one to five years. Transplantation 1987; 43: 197.
    • (1987) Transplantation , vol.43 , pp. 197
    • Kahn, B.D.1    Flechner, S.M.2    Lorber, M.I.3    Golden, D.4    Conley, S.5    Van Buren, C.T.6
  • 5
    • 0026338009 scopus 로고
    • Biliary secretion of bile acids, lipids, and bilirubin by the transplanted liver: A quantitative study in patients on cyclosporine
    • Theilman L, Otto G, Arnold J, Gmelin K, Stiehl A. Biliary secretion of bile acids, lipids, and bilirubin by the transplanted liver: a quantitative study in patients on cyclosporine. Transplantation 1991; 52: 1020.
    • (1991) Transplantation , vol.52 , pp. 1020
    • Theilman, L.1    Otto, G.2    Arnold, J.3    Gmelin, K.4    Stiehl, A.5
  • 6
    • 0010535140 scopus 로고
    • The bile acid independent flow is reduced in the transplanted liver
    • Friman S, Persson H, Karlberg I, Svanvik J The bile acid independent flow is reduced in the transplanted liver. Transpl Int 1992; 5 (suppl): S163.
    • (1992) Transpl Int , vol.5 , Issue.SUPPL.
    • Friman, S.1    Persson, H.2    Karlberg, I.3    Svanvik, J.4
  • 7
    • 0028305735 scopus 로고
    • Bile acid metabolism and biliary secretion in patients receiving orthotopic liver transplants: Differing effects of cyclosporine and FK506
    • McCashland TM, Donovan JP, Amelsberg A, et al. Bile acid metabolism and biliary secretion in patients receiving orthotopic liver transplants: differing effects of cyclosporine and FK506. Hepatology 1994; 19: 1381.
    • (1994) Hepatology , vol.19 , pp. 1381
    • McCashland, T.M.1    Donovan, J.P.2    Amelsberg, A.3
  • 8
    • 0023222218 scopus 로고
    • Cyclosporine A-induced cholestasis: The mechanism in a rat model
    • Stone BG, Udani M, Sanghyi A, et al. Cyclosporine A-induced cholestasis: the mechanism in a rat model. Gastroenterology 1987; 93: 344.
    • (1987) Gastroenterology , vol.93 , pp. 344
    • Stone, B.G.1    Udani, M.2    Sanghyi, A.3
  • 9
    • 0023684797 scopus 로고
    • Cholestatic effect of cyclosporine in the rat: An inhibition of bile acid secretion
    • Le Thai B, Dumont M, Nichel A, Erlinger S, Houssin D. Cholestatic effect of cyclosporine in the rat: an inhibition of bile acid secretion. Transplantation 1988; 46: 510.
    • (1988) Transplantation , vol.46 , pp. 510
    • Le Thai, B.1    Dumont, M.2    Nichel, A.3    Erlinger, S.4    Houssin, D.5
  • 10
  • 11
    • 0025294874 scopus 로고
    • Inhibition of hepatocytary vesicular transport by cyclosporin a in the rat: Relationship with cholestasis and hyperbilirubinemia
    • Roman ID, Monte MJ, Gonzalez-Buitrago JM, Esteller A, Jimenez R. Inhibition of hepatocytary vesicular transport by cyclosporin A in the rat: relationship with cholestasis and hyperbilirubinemia. Hepatology 1990; 12: 83.
    • (1990) Hepatology , vol.12 , pp. 83
    • Roman, I.D.1    Monte, M.J.2    Gonzalez-Buitrago, J.M.3    Esteller, A.4    Jimenez, R.5
  • 12
    • 0028924774 scopus 로고
    • Influence of liver transplantation and cyclosporine on bile secretion: An experimental study in the rat
    • Svensson G, Holmberg SB, Friman S. Influence of liver transplantation and cyclosporine on bile secretion: an experimental study in the rat. Transpl Int 1995; 8: 27.
    • (1995) Transpl Int , vol.8 , pp. 27
    • Svensson, G.1    Holmberg, S.B.2    Friman, S.3
  • 13
    • 0027320960 scopus 로고
    • Inhibition by cyclosporin a of adenosine triphosphate-dependent transport from the hepatocyte into bile
    • Kadmon M, Klunemann C, Bohme M, et al. Inhibition by cyclosporin A of adenosine triphosphate-dependent transport from the hepatocyte into bile. Gastroenterology 1993; 104: 1507.
    • (1993) Gastroenterology , vol.104 , pp. 1507
    • Kadmon, M.1    Klunemann, C.2    Bohme, M.3
  • 14
    • 0025845457 scopus 로고
    • Cyclosporine a blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis
    • Princen HMG, Meijer P, Wolthers BG, Vonk RJ, Kuipers F. Cyclosporine A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis. Biochem J 1991; 275: 501.
    • (1991) Biochem J , vol.275 , pp. 501
    • Princen, H.M.G.1    Meijer, P.2    Wolthers, B.G.3    Vonk, R.J.4    Kuipers, F.5
  • 15
    • 0017687615 scopus 로고
    • Biliary lipid secretion in cholesterol gallstone disease: The effect of cholecystectomy and obesity
    • Shaffer EA, Small DM. Biliary lipid secretion in cholesterol gallstone disease: the effect of cholecystectomy and obesity. J Clin Invest 1977; 59: 828.
    • (1977) J Clin Invest , vol.59 , pp. 828
    • Shaffer, E.A.1    Small, D.M.2
  • 16
    • 0024443616 scopus 로고
    • Cholestasis in the rat by means of intravenous administration of cyclosporine vehicle, Cremophor EL
    • Roman ID, Monte MJ, Esteller A, Jimenez R. Cholestasis in the rat by means of intravenous administration of cyclosporine vehicle, Cremophor EL. Transplantation 1989; 48: 554.
    • (1989) Transplantation , vol.48 , pp. 554
    • Roman, I.D.1    Monte, M.J.2    Esteller, A.3    Jimenez, R.4
  • 17
    • 0026641666 scopus 로고
    • Inhibition of biliary lipid and protein secretion by cyclosporine a in the rat
    • Galan AI, Roman ID, Munoz ME, et al. Inhibition of biliary lipid and protein secretion by cyclosporine A in the rat. Biochem Pharmacol 1992; 44: 1105.
    • (1992) Biochem Pharmacol , vol.44 , pp. 1105
    • Galan, A.I.1    Roman, I.D.2    Munoz, M.E.3
  • 18
    • 0027458713 scopus 로고
    • The effect of cyclosporine and liver autotransplantation on bile flow and composition in dogs
    • Sutherland FR, Preshaw RM, Shaffer EA. The effect of cyclosporine and liver autotransplantation on bile flow and composition in dogs. Transplantation 1993; 55: 237.
    • (1993) Transplantation , vol.55 , pp. 237
    • Sutherland, F.R.1    Preshaw, R.M.2    Shaffer, E.A.3
  • 19
    • 0022385999 scopus 로고
    • Pharmacokinetic profiles of cyclosporine in rats: Influence of route of administration and dosage
    • Wassef R, Cohen Z, Langer B. Pharmacokinetic profiles of cyclosporine in rats: influence of route of administration and dosage. Transplantation 1985; 40: 489.
    • (1985) Transplantation , vol.40 , pp. 489
    • Wassef, R.1    Cohen, Z.2    Langer, B.3
  • 20
    • 0016659973 scopus 로고
    • Circadian rhythm of biliary excretion and its control mechanisms in rats with chronic biliary drainage
    • Ho KJ, Drummond JL. Circadian rhythm of biliary excretion and its control mechanisms in rats with chronic biliary drainage. Am J Physiol 1975; 229: 1427.
    • (1975) Am J Physiol , vol.229 , pp. 1427
    • Ho, K.J.1    Drummond, J.L.2
  • 21
    • 72849179070 scopus 로고
    • Enzymatic analysis of steroid hormones
    • Talalay P. Enzymatic analysis of steroid hormones. Methods Biochem Anal 1960; 8: 119.
    • (1960) Methods Biochem Anal , vol.8 , pp. 119
    • Talalay, P.1
  • 22
    • 0016951805 scopus 로고
    • Bilirubin secretion and conjugation in the Crigler-Najjar syndrome type II
    • Gordon ER, Shaffer EA, Sass-Kortsak A. Bilirubin secretion and conjugation in the Crigler-Najjar syndrome type II. Gastroenterology 1976; 70: 761.
    • (1976) Gastroenterology , vol.70 , pp. 761
    • Gordon, E.R.1    Shaffer, E.A.2    Sass-Kortsak, A.3
  • 23
    • 0028130226 scopus 로고
    • Effects of obesity on bile formation and biliary lipid secretion in the genetically obese JCR:LA-corpulent rat
    • St. George CM, Russell JC, Shaffer EA. Effects of obesity on bile formation and biliary lipid secretion in the genetically obese JCR:LA-corpulent rat. Hepatology 1994; 20: 1541.
    • (1994) Hepatology , vol.20 , pp. 1541
    • St. George, C.M.1    Russell, J.C.2    Shaffer, E.A.3
  • 24
    • 0029092641 scopus 로고
    • Effects of liver transplantation on bile formation and biliary lipid secretion in the Sprague-Dawley rat
    • Chan FKL, Zhang Y, Sutherland FR, Shaffer EA. Effects of liver transplantation on bile formation and biliary lipid secretion in the Sprague-Dawley rat. Hepatology 1995; 22: 1254.
    • (1995) Hepatology , vol.22 , pp. 1254
    • Chan, F.K.L.1    Zhang, Y.2    Sutherland, F.R.3    Shaffer, E.A.4
  • 25
    • 0018092980 scopus 로고
    • Critical tables for calculating the cholesterol saturation of native bile
    • Carey MC. Critical tables for calculating the cholesterol saturation of native bile. J Lipid Res 1978; 19: 945.
    • (1978) J Lipid Res , vol.19 , pp. 945
    • Carey, M.C.1
  • 26
    • 0022504623 scopus 로고
    • Rapid computation with the personal computer of the percent cholesterol saturation of bile samples
    • Kuroki S, Cohen BI, Carey MC, Mosbach EH. Rapid computation with the personal computer of the percent cholesterol saturation of bile samples. J Lipid Res 1986; 27: 442.
    • (1986) J Lipid Res , vol.27 , pp. 442
    • Kuroki, S.1    Cohen, B.I.2    Carey, M.C.3    Mosbach, E.H.4
  • 27
    • 0024548006 scopus 로고
    • Cholestasis of total parenteral nutrition: Bile acid and bile lipid metabolism in parenterally nourished rats
    • Lirussi F, Vaja S, Murphy GM, Dowling RH. Cholestasis of total parenteral nutrition: bile acid and bile lipid metabolism in parenterally nourished rats. Gastroenterology 1989; 96: 493.
    • (1989) Gastroenterology , vol.96 , pp. 493
    • Lirussi, F.1    Vaja, S.2    Murphy, G.M.3    Dowling, R.H.4
  • 28
    • 0026497882 scopus 로고
    • Glutathione as a primary osmotic driving force in hepatic bile formation
    • Ballatori N, Truong A. Glutathione as a primary osmotic driving force in hepatic bile formation. Am J Physiol 1992; 26: G617.
    • (1992) Am J Physiol , vol.26
    • Ballatori, N.1    Truong, A.2
  • 30
    • 0016417052 scopus 로고
    • Biliary lipid output during three meals and an overnight fast: Part II. Effect of chenodeoxycholic acid treatment in gallstone subjects
    • Northfield TC, LaRusso NF, Hoffmann AF, Thistle JL. Biliary lipid output during three meals and an overnight fast: Part II. Effect of chenodeoxycholic acid treatment in gallstone subjects. Gut 1975; 16: 12.
    • (1975) Gut , vol.16 , pp. 12
    • Northfield, T.C.1    LaRusso, N.F.2    Hoffmann, A.F.3    Thistle, J.L.4
  • 31
    • 0021145408 scopus 로고
    • Rapid kinetic analysis of the bile salt-dependent secretion of phospholipid, cholesterol and a plasma membrane enzyme into bile
    • Lowe PJ, Barnwell SG, Coleman R. Rapid kinetic analysis of the bile salt-dependent secretion of phospholipid, cholesterol and a plasma membrane enzyme into bile. Biochem J 1984; 222: 631.
    • (1984) Biochem J , vol.222 , pp. 631
    • Lowe, P.J.1    Barnwell, S.G.2    Coleman, R.3
  • 32
    • 0023280162 scopus 로고
    • Biochemistry of bile secretion
    • Coleman R. Biochemistry of bile secretion. Biochem J 1987; 244: 249.
    • (1987) Biochem J , vol.244 , pp. 249
    • Coleman, R.1
  • 33
    • 0025000828 scopus 로고
    • Bile acid secretion, bile flow and biliary lipid secretion in humans
    • Hofmann AF. Bile acid secretion, bile flow and biliary lipid secretion in humans. Hepatology 1990; 12 (suppl): 17S.
    • (1990) Hepatology , vol.12 , Issue.SUPPL.
    • Hofmann, A.F.1
  • 34
    • 0017927811 scopus 로고
    • Mechanisms of secretion of biliary lipids: Role of a microtubular system in hepatocellular transport of biliary lipids in the rat
    • Gregory DH, Vlahcevic ZR, Prugh MF, Swell L. Mechanisms of secretion of biliary lipids: role of a microtubular system in hepatocellular transport of biliary lipids in the rat. Gastroenterology 1978; 74: 93.
    • (1978) Gastroenterology , vol.74 , pp. 93
    • Gregory, D.H.1    Vlahcevic, Z.R.2    Prugh, M.F.3    Swell, L.4
  • 35
    • 0001203098 scopus 로고
    • Lipid alteration in the hepatocyte basolateral sinusoidal membrane (BLM) domain may explain cyclosporine (CsA) induced cholestasis in the rat Abstract
    • Whitington PF, Dudeja P, Hecht JR, Whitington SH, Brasitus TA. Lipid alteration in the hepatocyte basolateral sinusoidal membrane (BLM) domain may explain cyclosporine (CsA) induced cholestasis in the rat Abstract. Hepatology 1988; 8: 1363.
    • (1988) Hepatology , vol.8 , pp. 1363
    • Whitington, P.F.1    Dudeja, P.2    Hecht, J.R.3    Whitington, S.H.4    Brasitus, T.A.5
  • 36
    • 0020639821 scopus 로고
    • Binding of cyclosporine by human lymphocytes and phospholipid vesicles
    • Le Grue, Friedman AW, Kahan BD. Binding of cyclosporine by human lymphocytes and phospholipid vesicles. J Immunol 1983; 131: 712.
    • (1983) J Immunol , vol.131 , pp. 712
    • Le Grue1    Friedman, A.W.2    Kahan, B.D.3
  • 37
    • 0019351564 scopus 로고
    • Effects of sulfobromophthalein excretion on biliary lipid secretion in humans and dogs
    • Shaffer EA, Preshaw RM. Effects of sulfobromophthalein excretion on biliary lipid secretion in humans and dogs. Am J Physiol 1981; 240: G85.
    • (1981) Am J Physiol , vol.240
    • Shaffer, E.A.1    Preshaw, R.M.2
  • 38
    • 0025147358 scopus 로고
    • The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat
    • Henkjan JK, Wolbers MJ, Havinga R, et al. The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat. Gastroenterology 1990; 99: 1485.
    • (1990) Gastroenterology , vol.99 , pp. 1485
    • Henkjan, J.K.1    Wolbers, M.J.2    Havinga, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.