Impact of portal branch ligation on tissue regeneration, microcirculatory response and microarchitecture in portal blood-deprived and undeprived liver tissue

Microvascular Research

Volumn 81, Issue 3, 2011, Pages 274-280

  Gock, Michael ^a   Eipel, Christian ^a   Linnebacher, Michael ^a   Klar, Ernst ^a   Vollmar, Brigitte ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Intravital microscopy; Liver blood flow; Liver regeneration; Shear stress; VEGF

Indexed keywords

CYCLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BLOOD FLOW VELOCITY; CONTROLLED STUDY; ERYTHROCYTE CIRCULATION TIME; ERYTHROCYTE PARAMETERS; FLUORESCENCE MICROSCOPY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTRAVITAL MICROSCOPY; LEUKOCYTE AGGREGATION; LIVER BLOOD FLOW; LIVER BLOOD VESSEL; LIVER CIRCULATION; LIVER HYPERTROPHY; LIVER NECROSIS; LIVER PERFUSION; LIVER REGENERATION; LIVER SINUSOID; LIVER WEIGHT; MICROCIRCULATION; MICROSCOPY; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHEAR STRESS; VASOCONSTRICTION; VEIN LIGATION;

ANIMALS; APOPTOSIS; ATROPHY; BLOOD FLOW VELOCITY; BODY WEIGHT; CELL ADHESION; CELL PROLIFERATION; ENDOTHELIAL CELLS; ERYTHROCYTES; HEPATOCYTES; LEUKOCYTES; LIGATION; LIVER; LIVER CIRCULATION; LIVER REGENERATION; MICROCIRCULATION; NECROSIS; ORGAN SIZE; PORTAL VEIN; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, SPRAGUE-DAWLEY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 79954598742     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2011.03.005     Document Type: Article

References (48)

1. Abdalla E.K., Vauthey J.N., Ellis L.M., Ellis V., Pollock R., Broglio K.R. Recurrence and outcomes following hepatic resection, radiofrequency ablation, and combined resection/ablation for colorectal liver metastases. Ann. Surg. 2004, 239:818-825.
2. Akbulut H., Altuntas F., Akbulut K.G., Ozturk G., Cindoruk M., Unal E., Icli F. Prognostic role of serum vascular endothelial growth factor, basic fibroblast growth factor and nitric oxide in patients with colorectal carcinoma. Cytokine 2002, 20:184-190.
3. Ando J., Tsuboi H., Korenaga R., Takada Y., Toyama S.N., Miyasaka M., Kamiya A. Shear stress inhibits adhesion of cultured mouse endothelial cells to lymphocytes by downregulating VCAM-1 expression. Am. J. Physiol. 1994, 267:679-687.
4. Bilodeau M., Aubry M.C., Houle R., Burnes P.N., Ethier C. Evaluation of hepatocyte injury following partial ligation of the left portal vein. J. Hepatol. 1999, 30:29-37.
5. Bismuth H., Castaing D., Houssin D. Hepatic and Portal Surgery in the Rat. Masson Paris 1980, 1980:27-44.
6. Blindenbacher A., Wang X., Langer I., Savino R., Terracciano L., Heim M.H. Interleukin 6 is important for survival after partial hepatectomy in mice. Hepatology 2003, 38:674-682.
7. Choti M.A., Sitzmann J.V., Tiburi M.F., Sumetchotimetha W., Rangsin R., Schulick R.D. Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann. Surg. 2002, 235:759-766.
8. De Jong K.P., Lont H.E., Bijma A.M., Brouwers M.A., de Vries E.G., van Veen M.L. The effect of partial hepatectomy on tumor growth in rats: in vivo and in vitro studies. Hepatology 1995, 22:1263-1272.
9. Eipel C., Bordel R., Nickels R.M., Menger M.D., Vollmar B. Impact of leukocytes and platelets in mediating hepatocyte apoptosis in a rat model of systemic endotoxemia. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286:769-776.
10. Eipel C., Glanemann M., Nuessler A.K., Menger M.D., Neuhaus P., Vollmar B. Ischemic preconditioning impairs liver regeneration in extended reduced-size livers. Ann. Surg. 2005, 241:477-484.
11. Elias D., De Baere T., Roche A., Ducreux M., Leclere J., Lasser P. During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma. Br. J. Surg. 1999, 86:784-788.
12. Ferrara N., Gerber H.P., LeCouter J. The biology of VEGF and its receptors. Nat. Med. 2003, 9:669-676.
13. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1995, 1:27-31.
14. Gross J.F., Aroesty J. Mathematical models of capillary flow: a critical review. Biorheology 1972, 9:225-264.
15. Gardi C., Arezzini B., Monaco B., De Montis M.G., Vecchio D., Comporti M. F2-isoprostane receptors on hepatic stellate cells. M. Lab. Invest. 2008, 88:124-131.
16. Gujral J.S., Bucci T.J., Farhood A., Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?. Hepatology 2001, 33:397-405.
17. Herman B., Nieminen A.L., Gores G.J., Lemasters J.J. Irreversible injury in anoxic hepatocytes precipitated by an abrupt increase in plasma membrane permeability. FASEB J. 1988, 2:146-151.
18. Huwer H., Nikoloudakis N., Rissland J., Vollmar B., Menger M.D., Schäfers H.J. In vivo analysis of microvascular injury after myocardial cryothermia. J. Surg. Res. 1998, 79:1-7.
19. Jeffery, G.M., Hickey, B.E., Hider, P., 2002. Follow-up strategies for patients treated for non-metastatic colorectal cancer. The Cochrane Database of Systematic Reviews Issue 1. Art. No.: CD002200.
20. Kawasaki S., Makuuchi M., Miyagawa S., Kakazu T. Radical operation after portal embolization for tumor of hilar bile duct. J. Am. Coll. Surg. 1994, 178:480-486.
21. Kerr J.F., Gobe G.C., Winterford C.M., Harmon B.V. Anatomical methods in cell death. Meth. Cell Biol. 1995, 46:1-27.
22. Kinoshita H., Sakai K., Hirohashi K., Igawa S., Yamazaki O., Kubo S. Preoperative portal vein embolization for hepatocellular carcinoma. World J. Surg. 1986, 10:803-808.
23. Kokudo N., Tada K., Seki M., Ohta H., Azekura K., Ueno M. Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization. Hepatology 2001, 34:267-272.
24. Kollmar O., Corsten M., Scheuer C., Vollmar B., Schilling M.K., Menger M.D. Portal branch ligation induces a hepatic arterial buffer response, microvascular remodeling, normoxygenation, and cell proliferation in portal blood-deprived liver tissue. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292:1534-1542.
25. Kollmar O., Rupertus K., Scheuer C., Nickels R.M., Haberl G.C., Tilton B., Menger M.D., Schilling M.K. CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1. Int. J. Cancer 2010, 126:1302-1315.
26. Marsden P.A., Heng H.H., Scherer S.W., Stewart R.J., Hall A.V., Shi X.M., Tsui L.C., Schappert K.T. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem. 1993, 268:17478-17488.
27. Mueller L., Goettsche J., Abdulgawad A., Vashist Y.K., Meyer J., Wilms C., Hillert C., Rogiers X., Broering D.C. Tumor growth-promoting cellular host response during liver atrophy after portal occlusion. Liver Int. 2005, 25:994-1001.
28. Nordlinger B., Vaillant J.C., Guiguet M., Balladur P., Paris F., Bachellier P., Jaeck D. Survival benefit of repeat liver resections for recurrent colorectal metastases: 143 cases Association Francaise de Chirurgie. J. Clin. Oncol. 1994, 12:1491-1496.
29. Ohno M., Cooke J.P., Dzau V.Z., Gibbons G.H. Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production Modulation by potassium channel blockade. J. Clin. Invest. 1995, 95:1363-1369.
30. Oyama T., Sadamori H., Matsukawa H., Murata H., Umeda Y., Watanabe Y., Ozaki M., Iwagaki H., Tanaka N., Yagi T. Small liver graft regenerates through immediate increase of HGF and IL-6-possible involvement of sinusoidal tensile/shear stress in small liver graft. Hepatogastroenterology 2007, 54:2078-2083.
31. Pawlik T.M., Izzo F., Cohen D.S., Morris J.S., Curley S.A. Combined resection and radiofrequency ablation for advanced hepatic malignancies: results in 172 patients. Ann. Surg. Oncol. 2003, 10:1059-1069.
32. Rappaport A.M. The microcirculatory hepatic unit. Microvasc. Res. 1973, 6:212-228.
33. Richter S., Vollmar B., Muecke I., Post S., Menger M.D. Hepatic arteriolo-portal venular shunting guarantees maintenance of nutritional microvascular supply in hepatic arterial buffer response of rat livers. J. Physiol. 2001, 531:193-201.
34. Reynaert H., Thompson M.G., Thomas T., Geerts A. Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension. Gut 2002, 50:571-581.
35. Rocheleau B., Ethier C., Houle R., Huet P.M., Bilodeau M. Hepatic artery buffer response following left portal vein ligation: its role in liver tissue homeostasis. Am. J. Physiol. Gastrointest. Liver Physiol. 1999, 277:1000-1007.
36. Rockey D.C. Hepatic blood flow regulation by stellate cells in normal and injured liver. Semin. Liver Dis. 2001, 21:337-349.
37. Rozga J., Jeppsson B., Bengmark S. Portal branch ligation in the rat. Reevaluation of a model. Am. J. Pathol. 1986, 125:300-308.
38. Sato Y., Koyama S., Tsukada K., Hatakeyama K. Acute portal hypertension reflecting shear stress is a trigger of liver regeneration following partial hepatectomy. Surg. Today 1997, 27:518-526.
39. Schäfer T., Scheuer C., Roemer K., Menger M.D., Vollmar B. Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death. FASEB J. 2003, 17:660-667.
40. Selzner N., Selzner M., Odermatt B., Tian Y., Van Rooijen N., Clavien P.A. ICAM-1 triggers liver regeneration through leukocyte recruitment and Kupffer cell-dependent release of TNF-alpha/IL-6 in mice. Gastroenterology 2003, 124:692-700.
41. Takahashi Y., Kitadai Y., Bucana C.D., Cleary K.R., Ellis L.M. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res. 1995, 55:3964-3968.
42. Um S.H., Nishida O., Tokubayashi M., Kimura F., Takimoto Y., Yoshioka H., Inque R., Kita T. Hemodynamic changes after ligation of a major branch of the portal vein in rats: comparison with rats with portal vein constriction. Hepatology 1994, 19:202-209.
43. Vollmar B., Glasz J., Leiderer R., Post S., Menger M.D. Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion. Am. J. Pathol. 1994, 145:1421-1431.
44. Vollmar B., Menger M.D., Glasz J., Leiderer R., Messmer K. Impact of leukocyte-endothelial cell interaction in hepatic ischemia reperfusion injury. Am. J. Physiol. Gastrointest. Liver Physiol. 1994, 267:786-793.
45. Warren R.S., Yuan H., Matli M.R., Gillett N.A., Ferrara N. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J. Clin. Invest. 1995, 95:1789-1797.
46. Windberger U., Bartholovitsch A., Plasenzotti R., Korak K.J., Heinze G. Whole blood viscosity, plasma viscosity and erythrocyte aggregation in nine mammalian species: reference values and comparison of data. Exp. Physiol. 2003, 88:431-440.
47. Xu H., Korneszczuk K., Karaa A., Lin T., Clemens M., Zhang J. Thromboxane A2 from Kupffer cells contributes to the hyperresponsiveness of hepatic portal circulation to endothelin-1 in endotoxemic rats. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 288:277-283.
48. Zhao H., Hiroi T., Hansen B.S., Rade J.J. Cyclic stretch induces cyclooxygenase-2 gene expression in vascular endothelial cells via activation of nuclear factor kappa-beta. Biochem. Biophys. Res. Commun. 2009, 389:599-601.