Ischemic preconditioning impairs liver regeneration in extended reduced-size livers

Annals of Surgery

Volumn 241, Issue 3, 2005, Pages 477-484

  Eipel, Christian ^a   Glanemann, Matthias ^b   Nuessler, Andreas K ^b   Menger, Michael D ^c   Neuhaus, Peter ^b   Vollmar, Brigitte ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN;

ANIMAL MODEL; ARTICLE; CELL CYCLE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPE; HEMODYNAMICS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LASER DOPPLER FLOWMETRY; LIVER BLOOD FLOW; LIVER HYPERPERFUSION; LIVER INJURY; LIVER ISCHEMIA; LIVER MICROCIRCULATION; LIVER PROTECTION; LIVER REGENERATION; LIVER REMNANT; LIVER RESECTION; LIVER SIZE; LIVER VEIN OBSTRUCTION; MALE; MICROCIRCULATION; MITOSIS; NONHUMAN; PORTAL HYPERTENSION; PRIORITY JOURNAL; RAT; REDUCED SIZE LIVER; REPERFUSION INJURY; SHEAR STRESS; SURVIVAL;

ANIMALS; CELL DIVISION; HEPATECTOMY; IMMUNOENZYME TECHNIQUES; ISCHEMIC PRECONDITIONING; KI-67 ANTIGEN; LASER-DOPPLER FLOWMETRY; LIVER; LIVER CIRCULATION; LIVER REGENERATION; MALE; MICROCIRCULATION; MICROSCOPY, FLUORESCENCE; RATS; RATS, WISTAR;

EID: 14544308915     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000154264.41201.51     Document Type: Article

References (51)

1. Bilzer M, Gerbes AL. Preservation injury of the liver: mechanisms and novel therapeutic strategies. J Hepatol. 2000;32:508-515.
2. Serracino-Inglott F, Habib NA, Mathie RT. Hepatic ischemia-reperfusion injury. Am J Surg. 2001;181:160-166.
3. Belghiti J, Noun R, Malafosse R, et al. Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg. 1999;229:369-375.
4. Huguet C, Gavelli A, Bona S. Hepatic resection with ischemia of the liver exceeding one hour. J Am Coll Surg. 1994;178:454-458.
5. Lemasters JJ, Thurman RG. Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol. 1997;37:327-338.
6. Arii S, Teramoto K, Kawamura T. Current progress in the understanding of and therapeutic strategies for ischemia and reperfusion injury of the liver. J Hepatobiliary Pancreat Surg. 2003;10:189-194.
7. Teoh NC, Farrell GC. Hepatic ischemia reperfusion injury: pathogenic mechanisms and basis for hepatoprotection. J Gastroenterol Hepatol. 2003;18:891-902.
8. Selzner M, Clavien PA. Fatty liver in liver transplantation and surgery. Semin Liver Dis. 2001;21:105-113.
9. Ezaki T, Seo Y, Tomoda H, et al. Partial hepatic resection under intermittent hepatic inflow occlusion in patients with chronic liver disease. Br J Surg. 1992;79:224-226.
10. Glanemann M, Langrehr JM, Stange BJ, et al. Clinical implications of hepatic preservation injury after adult liver transplantation. Am J Transplant. 2003;3:1003-1009.
11. Carini R, Albano E. Recent insights on the mechanisms of liver preconditioning. Gastroenterology. 2003;125:1480-1491.
12. Koti RS, Seifalian AM, Davidson BR. Protection of the liver by ischemic preconditioning: a review of mechanisms and clinical applications. Dig Surg. 2003;20:383-396.
13. Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol. 2003;284:G15-26.
14. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986; 74:1124-1136.
15. Carden DL, Granger DN. Pathophysiology of ischaemia-reperfusion injury. J Pathol. 2000;190:255-266.
16. Glanemann M, Vollmar B, Nussler AK, et al. Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-state. J Hepatol. 2003;38:59-66.
17. Yoshizumi T, Yanaga K, Soejima Y, et al. Amelioration of liver injury by ischaemic preconditioning. Br J Surg. 1998;85:1636-1640.
18. Yadav SS, Sindram D, Perry DK, et al. Ischemic preconditioning protects the mouse liver by inhibition of apoptosis through a caspase-dependent pathway. Hepatology. 1999;30:1223-1231.
19. Teoh N, Dela Pena A, Farrell G. Hepatic ischemic preconditioning in mice is associated with activation of NF-kappaB, p38 kinase, and cell cycle entry. Hepatology. 2002;36:94-102.
20. Clavien PA, Selzner M, Rudiger HA, et al. A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning. Ann Surg. 2003;238:843-850.
21. Troisi R, Cammu G, Militemo G, et al. Modulation of portal graft inflow: a necessity in adult living-donor liver transplantation? Ann Surg. 2003;237:429-436.
22. Man K, Fan ST, Lo CM, et al. Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression. Ann Surg. 2003;237:256-264.
23. Man K, Lo CM, Ng IO, et al. Liver transplantation in rats using small-for-size grafts: a study of hemodynamic and morphological changes. Arch Surg. 2001;136:280-285.
24. Glanemann M, Strenziok R, Kuntze R, et al. Ischemic preconditioning and methylprednisolone both equally reduce hepatic ischemia/reperfusion injury. Surgery. 2004;135:203-214.
25. Higgins GM, Anderson RM. Experimental pathology of the liver. Arch Pathol. 1931;12:186-202.
26. Gerlach C, Sakkab DY, Scholzen T, et al. Ki-67 expression during rat liver regeneration after partial hepatectomy. Hepatology. 1997;26:573-578.
27. Kazuo H, Nishida T, Seiyama A, et al. Recovery of blood flow and oxygen transport after temporary ischemia of rat liver. Am J Physiol. 1998;275:H243-249.
28. Nishida T, Ueshima S, Kazuo H, et al. Vagus nerve is involved in lack of blood reflow into sinusoids after rat hepatic ischemia. Am J Physiol Heart Circ Physiol. 2000;278:H1565-1570.
29. Eipel C, Bordel R, Nickels RM, et al. Impact of leukocytes and platelets in mediating hepatocyte apoptosis in a rat model of systemic endotoxemia. Am J Physiol Gastrointest Liver Physiol. 2004;286:G769-776.
30. Schäfer T, Scheuer C, Roemer K, et al. Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death. FASEB J. 2003;17:660-667.
31. Rappaport AM. The microcirculatory hepatic unit. Microvasc Res. 1973;6:212-228.
32. Richter S, Vollmar B, Mucke I, et al. Hepatic arteriolo-portal venular shunting guarantees maintenance of nutritional microvascular supply in hepatic arterial buffer response of rat livers. J Physiol. 2001;531:193-201.
33. Gross JF, Aroesty J. Mathematical models of capillary flow: a critical review. Biorheology. 1972;9:225-264.
34. Selzner N, Rudiger H, Graf R, et al. Protective strategies against ischemic injury of the liver. Gastroenterology. 2003;125:917-936.
35. Peralta C, Closa D, Hotter G, et al. Liver ischemic preconditioning is mediated by the inhibitory action of nitric oxide on endothelin. Biochem Biophys Res Commun. 1996;229:264-270.
36. Nilsson B, Friman S, Gustafsson BI, et al. Preconditioning protects against ischemia/reperfusion injury of the liver. J Gastrointest Surg. 2000;4:44-49.
37. Zapletal C, Maksan SM, Lehmann T, et al. Ischemic preconditioning improves liver microcirculation after ischemia/reperfusion. Transplant Proc. 1999;31:3260-3262.
38. Wang HH, Lautt WW. Evidence of nitric oxide, a flow-dependent factor, being a trigger of liver regeneration in rats. Can J Physiol Pharmacol. 1998;76:1072-1079.
39. Sato Y, Tsukada K, Hatakeyama K. Role of shear stress and immune responses in liver regeneration after a partial hepatectomy. Surg Today. 1999;29:1-9.
40. Niiya T, Murakami M, Aoki T, et al. Immediate increase of portal pressure, reflecting sinusoidal shear stress, induced liver regeneration after partial hepatectomy. J Hepatobiliary Pancreat Surg. 1999;6:275-280.
41. Eguchi S, Yanaga K, Sugiyama N, et al. Relationship between portal venous flow and liver regeneration in patients after living donor right-lobe liver transplantation. Liver Transpl. 2003;9:547-551.
42. Marcos A, Olzinski AT, Ham JM, et al. The interrelationship between portal and arterial blood flow after adult to adult living donor liver transplantation. Transplantation. 2000;70:1697-1703.
43. Troisi R, de Hemptinne B. Clinical relevance of adapting portal vein flow in living donor liver transplantation in adult patients. Liver Transpl. 2003;9:S36-41.
44. Goldstein MJ, Salame E, Kapur S, et al. Analysis of failure in living donor liver transplantation: differential outcomes in children and adults. World J Surg. 2003;27:356-364.
45. Kiuchi T, Kasahara M, Uryuhara K, et al. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors. Transplantation. 1999;67:321-327.
46. Lo CM, Fan ST, Liu CL, et al. Minimum graft size for successful living donor liver transplantation. Transplantation. 1999;68:1112-1116.
47. Kiuchi T, Tanaka K, Ito T, et al. Small-for-size graft in living donor liver transplantation: how far should we go? Liver Transpl. 2003;9:S29-35.
48. Panis Y, McMullan DM, Emond JC. Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection. Surgery. 1997;121:142-149.
49. Yamada F, Abe T, Saito T, et al. Ischemic preconditioning enhances regenerative capacity of hepatocytes after prolonged ischemia. Transplant Proc. 2001;33:956.
50. Ishii S, Abe T, Saito T, et al. Effects of preconditioning on ischemia/reperfusion injury of hepatocytes determined by immediate early gene transcription. J Hepatobiliary Pancreat Surg. 2001;8:461-468.
51. Kountouras J, Boura P, Lygidakis NJ. Liver regeneration after hepatectomy. Hepatogastroenterology. 2001;48:556-562.