Matrix vesicles in osteomalacic hypophosphatasia bone contain apatite- like mineral crystals

American Journal of Pathology

Volumn 151, Issue 6, 1997, Pages 1555-1561

  Anderson, H Clarke ^a   Hsu, Howard H ^a   Morris, David C ^a,d   Fedde, Kenton N ^b   Whyte, Michael P ^b,c  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

^c SHRINERS HOSPITAL FOR CHILDREN   (United States)

^d GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE ISOENZYME; APATITE; MINERAL;

ARTICLE; BONE MATRIX; BONE MINERALIZATION; CALCIFICATION; CLINICAL ARTICLE; CRYSTAL; ENZYME DEFICIENCY; FEMALE; FETUS; HUMAN; HUMAN TISSUE; HYPOPHOSPHATEMIA; MALE; NEWBORN; OSTEOMALACIA; PRIORITY JOURNAL; RICKETS;

APATITES; BONE AND BONES; BONE MATRIX; CARTILAGE; CRYSTALLIZATION; FEMALE; GROWTH PLATE; HUMANS; HYPOPHOSPHATASIA; INFANT, NEWBORN; MALE; OSTEOMALACIA; PREGNANCY;

EID: 0030696783     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Weiss MJ, Henthorn PS, Lafferty MK, Slaughter C, Raducha M, Harris H: Isolation and characterization of a cDNA encoding a human liver/ bone/kidney-type alkaline phosphatase. Proc Natl Acad Sci USA 1986, 83:7182-7186
2. Anderson HC, Sajdera SW: Calcification of rachitic cartilage to study matrix vesicle function. Fed Proc 1976, 35:148-153
3. Gutman AB, Yu TF: A concept of the role of enzymes in endochondral calcification. Metabolic Interrelations, vol 2. New York, Josiah Macy Jr Foundation 1950, pp 167-190
4. Matsuzawa T, Anderson HC: Phosphatases of epiphyseal cartilage studied with electron microscopic cytochemical methods. J Histochem Cytochem 1971, 19:801-808
5. Robison R, Rosenheim AH: Calcification of hypertrophic cartilage in vitro. Biochem J 1934, 28:684-698
6. Anderson HC, Morris DC: Mineralization. Handbook Exp Pharmacol 1993, 107:267-298
7. Bellows CG, Rubin JE, Heersch JNM: Initiation and progression of mineralization of bone nodules formed in vitro: the role of alkaline phosphatase and organic phosphate. Bone Miner 1991, 14:27-40
8. Fallon MD, Whyte MP, Teitelbaum SL: Stereospecific inhibition of alkaline phosphatase by L-tetramisole prevents in vitro cartilage calcification. Lab Invest 1980, 43:489-494
9. Hsu HHT, Anderson HC: A simple and defined method to study calcification by isolated matrix vesicles: effect of ATP and vesicle phosphatase. Biochem Biophys Acta 1977, 500:162-172
10. McCance RA, Fairweather DV, Barrett AM, Morrison AB: Genetic, clinical, biochemical and pathological features of hypophosphatasia. Q J Med 1956, 25:523-538
11. Whyte MP, Magill HL, Fallon MD, Herrod HG: Infantile hypophosphatasia: normalization of circulating bone alkaline phosphatase activity followed by skeletal remineralization. J Pediatr 1986, 108:82-88
12. Anderson HC: Vesicles associated with calcification in the matrix of epiphyseal cartilage. J Cell Biol 1969, 41:59-72
13. Ali SY, Sajdera SW, Anderson HC: Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage. Proc Natl Acad Sci USA 1970, 67:1513-1520
14. +-ATPase) in growth plate cartilage. J Histochem Cytochem 1985, 33:925-932
15. Low JG: Biochemistry of the glycosyl-phosphatidylinositol membrane protein anchors. Biochem J 1987, 224:1-13
16. 45Ca calcium ions by matrix vesicles isolated from calcifying cartilage. Biochem J 1973, 134:647-650
17. Hsu HHT, Andersen HC: A role for ATPase in the mechanisms of ATP-dependent Ca and phosphate deposition by isolated rachitic matrix vesicles. Int J Biochem Cell Biol 1995, 27:1349-1356
18. Ornoy A, Adomian GE, Rimoin DL: Histologic and ultrastructural studies on the mineralization process in hypophosphatasia. Am J Med Genet 1985, 22:743-758
19. Terada S, Suzuki N, Ueno H, Uchid K, Kohama T: A congenital lethal form of hypophosphatasia: histologic and ultrastructural study. Acta Obstet Gynecol Scand 1996. 75:502-505
20. Caswell AM, Whyte MP, Russell RGG: Hypophosphatasia and the extracellular metabolism of inorganic pyrophosphate: clinical and laboratory aspects. Crit Rev Clin Lab Sci 1991, 28:175-232
21. Whyte MP: Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocr Rev 1994, 15:439-461
22. Swallow DM, Porvey S, Parkar M: Mapping for the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1. Ann Hum Genet 1986, 50:229-235
23. Fleisch H, Bisaz S: Mechanism of calcification: inhibitory role of pyrophosphate. Nature 1962, 195:911
24. Whyte MP, Walkenhorst DA, Fedde KN, Henthorn PS, Hill CS: Hypophosphatasia: levels of bone alkaline phosphatase immunoreactivity in serum reflect disease severity. J Clin Endocrinol Metab 1996, 81:2142-2148
25. Fedde KN, Henthorn PS, Whyte MP: Aberrant properties of alkaline phosphatase in patient fibroblasts correlate with clinical expressivity in severe forms of hypophosphatasia. J Clin Endocrinol Metab 1996, 81:2587-2594
26. Henthorn PS, Raducha M, Fedde KN, Lafferty MA, Whyte MP: Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia, Proc Natl Acad Sci USA 1992, 89: 9924-9928
27. Ozona K, Yamagata M, Michigami T, Nakaiima S, Sakai N, Satomurak, Yasui N, Okada S, Nakayama M: Identification of novel missense mutations (Phe 310 Leu and Gly 439 Ang) in a neonatal case of hypophosphatasia. J Clin Endocrinol Metab 1996, 81:4458-4461
28. Weiss MJ, Cole DEC, Ray K, Whyte MP, Lafferty MS, Mulivor RA, Harris H: A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a form of lethal hypophosphatasia, Proc Natl Acad Sci USA 1988, 85:7666-7669
29. Termine JD, Conn KM: Inhibition of apatite formation by phosphorylated metabolites and macromolecules. Calcif Tissue Res 1976, 22: 149-157
30. Wu LNY, Genge BR, Lloyd GC, Wuthier RE: Collagen binding proteins in collagenase-released matrix vesicles from cartilage. J Biol Chem 1991, 266:1195-1203