Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: Antagonism by aspirin and protein kinase inhibitors

FASEB Journal

Volumn 25, Issue 4, 2011, Pages 1417-1427

  Esser, Julia ^a   Gehrmann, Ulf ^a   Salvado, M Dolores ^a   Wetterholm, Anders ^a   Haeggström, Jesper Z ^a   Samuelsson, Bengt ^a   Gabrielsson, Susanne ^a   Scheynius, Annika ^a   Rådmark, Olof ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Acetylsalicylic acid; Eicosanoids; Macrophages; Toll like receptor 2

Indexed keywords

4,5 BIS(4 FLUOROANILINO)PHTHALIMIDE; ACETYLSALICYLIC ACID; CYCLIC AMP DEPENDENT PROTEIN KINASE; LEUKOTRIENE A4; LEUKOTRIENE C4 SYNTHASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE INHIBITOR; RAPAMYCIN; S6 KINASE; STAUROSPORINE; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG; WORTMANNIN; ZYMOSAN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; REGULATORY MECHANISM; UPREGULATION;

ASPIRIN; CELL DIFFERENTIATION; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; GLUTATHIONE TRANSFERASE; HUMANS; LEUKOTRIENE C4; MACROPHAGES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RECEPTORS, PROSTAGLANDIN E; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIROLIMUS; STAUROSPORINE; TOLL-LIKE RECEPTOR 2; ZYMOSAN;

EID: 79954584873     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-175828     Document Type: Article

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