Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains

Journal of Biological Chemistry

Volumn 279, Issue 31, 2004, Pages 32134-32141

  Yamada, Shuhei ^a,b   Busse, Marta ^a   Ueno, Momoyo ^b   Kelly, Olivia G ^c   Skarnes, William C ^c   Sugahara, Kazuyuki ^b   Kusche Gullberg, Marion ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DATA ACQUISITION; POLYSACCHARIDES;

HEPARAN SULFATE; HUMAN DISORDER;

GENES;

DISACCHARIDE; GLYCOSYLTRANSFERASE; HEPARAN SULFATE; POLYSACCHARIDE; PROTEOHEPARAN SULFATE;

ANIMAL CELL; ARTICLE; AUTOSOMAL DISORDER; CELL CULTURE; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; EXOSTOSIS; EXT1 GENE; EXT2 GENE; FIBROBLAST; GENE; GENE DISRUPTION; GENE MUTATION; GENE TRAP MUTATION; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; MOLECULAR SIZE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; SULFATION;

ANIMALS; ANIONS; BLOTTING, NORTHERN; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISACCHARIDES; DNA MUTATIONAL ANALYSIS; FIBROBLASTS; GENETIC TECHNIQUES; GROWTH SUBSTANCES; HEPARITIN SULFATE; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; MICE; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTAGENESIS; MUTATION; N-ACETYLGLUCOSAMINYLTRANSFERASES; NITROUS ACID; POLYSACCHARIDES; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS;

ANIMALIA; MAMMALIA;

EID: 3543041815     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312624200     Document Type: Article

References (47)

1. Bernfield, M., Gotte, M., Park, P. W., Reizes, O., Fitzgerald, M. L., Lincecum, J., and Zako, M. (1999) Annu. Rev. Biochem. 68, 729-777
2. Ornitz, D. M. (2000) Bioessays 22, 108-112
3. Selva, E. M., and Perrimon, N. (2001) Adv. Cancer Res. 83, 67-80
4. Forsberg, E., and Kjellen, L. (2001) J. Clin. Invest. 108, 175-180
5. Nybakken, K., and Perrimon, N. (2002) Biochim. Biophys. Acta 1573, 280-291
6. Sugahara, K., and Kitagawa, H. (2000) Curr. Opin. Struct. Biol. 10, 518-527
7. Lindahl, U., Kusche-Gullberg, M., and Kjellén, L. (1998) J. Biol. Chem. 273, 24979-24982
8. Esko, J. D., and Lindahl, U. (2001) J. Clin. Invest. 108, 169-173
9. Esko, J. D., and Selleck, S. B. (2002) Annu. Rev. Biochem. 71, 435-471
10. Salomon, L. (1963) J. Bone Jt. Surg. Br. 45, 292-304
11. Cook, A., Raskind, W., Blanton, S. H., Pauli, R. M., Gregg, R. G., Francomano, C. A., Puffenberger, E., Conrad, E. U., Schmale, G., Schellenberg, G., Wijsman, E., Hecht, J. T., Wells, D., and Wagner, M. J. (1993) Am. J. Hum. Genet. 53, 71-79
12. Hecht, J. T., Hogue, D., Strong, L. C., Hansen, M. F., Blanton, S. H., and Wagner, M. (1995) Am. J. Hum. Genet. 56, 1125-1131
13. Le Merrer, M., Legeai-Mallet, L., Jeannin, P. M., Horsthemke, B., Schinzel, A., Plauchu, H., Toutain, A., Achard, F., Munnich, A., and Maroteaux, P. (1994) Hum. Mol. Genet. 3, 717-722
14. Van Hul, W., Wuyts, W., Hendrickx, J., Speleman, F., Wauters, J., De Boulle, K, Van Roy, N., Bossuyt, P., and Willems, P. J. (1998) Genomics 47, 230-237
15. Wise, C. A., Clines, G. A., Massa, H., Trask, B. J., and Lovett, M. (1997) Genome Res. 7, 10-16
16. Wuyts, W., Van Hul, W., Hendrickx, J., Speleman, F., Wauters, J., De Boulle, K., Van Roy, N., Van Agtmael, T., Bossuyt, P., and Willems, P. J. (1997) Eur. J. Hum. Genet. 5, 382-389
17. Lind, T., Tufaro, F., McCormick, C., Lindahl, U., and Lidholt, K. (1998) J. Biol. Chem. 273, 26265-26268
18. McCormick, C., Leduc, Y., Martindale, D., Mattison, K., Esford, L., Dyer, A., and Tufaro, F. (1998) Nat. Genet. 19, 158-161
19. Kobayashi, S.-i., Morimoto, K.-i., Shimizu, T., Takahashi, M., Kurosawa, H., and Shirasawa, T. (2000) Biochem. Biophys. Res. Commun. 268, 860-867
20. McCormick, C., Duncan, G., Goutsos, K. T., and Tufaro, F. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 668-673
21. Senay, C., Lind, T., Muguruma, K., Tone, Y., Kitagawa, H., Sugahara, K., Lidholt, K., Lindahl, U., and Kusche-Gullberg, M. (2000) EMBO Reports 1, 282-286
22. Wei, G., Bai, X., Gabb, M. M., Bame, K. J., Koshy, T. I., Spear, P. G., and Esko, J. D. (2000) J. Biol. Chem. 275, 27733-27740
23. Kitagawa, H., Shimakawa, H., and Sugahara, K. (1999) J. Biol. Chem. 274, 13933-13937
24. Kim, B. T., Kitagawa, H., Tamura, J., Saito, T., Kusche-Gullberg, M., Lindahl, U., and Sugahara, K. (2001) Proc. Natl. Acad. Sci. U. S. A. 88, 7176-7181
25. Takei, Y., Ozawa, Y., Sato, M., Watanabe, A., and Tabata, T. (2004) Development 131, 73-82
26. Han, C., Belenkaya, T. Y., Khodoun, M., Tauchi, M., Lin, X., and Lin, X. (2004) Development 131, 1563-1575
27. Lin, X., Wei, G., Shi, Z., Dryer, L., Esko, J. D., Wells, D. E., and Matzuk, M. M. (2000) Dev. Biol. 224, 299-311
28. Toyoda, H., Kinoshita-Toyoda, A., and Selleck, S. B. (2000) J. Biol. Chem. 275, 2269-2275
29. Mitchell, K. J., Pinson, K. I., Kelly, O. G., Brennan, J., Zupicich, J., Scherz, P., Leighton, P. A., Goodrich, L. V., Lu, X., Avery, B. J., Tate, P., Dill, K., Pangilinan, E., Wakenight, P., Tessier-Lavigne, M., and Skarnes, W. C. (2001) Nat. Genet. 28, 241-249
30. Pejler, G., Bäckström, G., Lindahl, U., Paulsson, M., Dziadek, M., Fujiwara, S., and Timpl, R. (1987) J. Biol. Chem. 262, 5036-5043
31. Hagner-McWhirter, A., Hannesson, H. H., Campbell, P., Westley, J., Roden, L., Lindahl, U., and Li, J. P. (2000) Glycobiology 10, 159-171
32. Shively, J. E., and Conrad, H. E. (1976) Biochemistry 15, 3932-3942
33. Cheung, W.-F., Eriksson, I., Kusche-Gullberg, M., Lindahl, U., and Kjellén, L. (1996) Biochemistry 35, 5250-5256
34. Jat, P. S., Cepko, C. L., Mulligan, R. C., and Sharp, P. A. (1986) Mol. Cell. Biol. 6, 1204-1217
35. Maccarana, M., Sakura, Y., Twada, A., Yoshida, K., and Lindahl, U. (1996) J. Biol. Chem. 271, 17804-17810
36. Kishibe, J., Yamada, S., Okada, Y., Sato, J., Ito, A., Miyazaki, K., and Sugahara, K. (2000) J. Biol. Chem. 275, 15321-15329
37. Kure, S., and Yoshie, O. (1986) J. Immunol. 137, 3900-3908
38. Lin, X., Gan, L., Klein, W. H., and Wells, D. (1998) Biochem. Biophys. Res. Commun. 248, 738-743
39. Bullock, S. L., Fletcher, J. M., Beddington, R. S. P., and Wilson, V. A. (1998) Genes Dev. 12, 1897-1906
40. Forsberg, E., Pejler, G., Ringvall, M., Lunderius, C., Tomasini-Johansson, B., Kusche-Gullberg, M., Eriksson, I., Ledin, J., Hellman, L., and Kjellén, L. (1999) Nature 400, 773-776
41. Ringvall, M., Ledin, J., Holmborn, K., van Kuppevelt, T., Ellin, F., Eriksson, I., Olofsson, A. M., Kjellen, L., and Forsberg, E. (2000) J. Biol. Chem. 275, 25926-25930
42. Inatani, M., Irie, F., Plump, A. S., Tessier-Lavigne, M., and Yamaguchi, Y. (2003) Science 302, 1044-1046
43. Li, J. P., Gong, F., Hagner-McWhirter, A., Forsberg, E., Abrink, M., Kisilevsky, R., Zhang, X., and Lindahl, U. (2003) J. Biol. Chem. 278, 28363-28366
44. Zak, B. M., Crawford, B. E., and Esko, J. D. (2002) Biochim. Biophys. Acta 1573, 346-355
45. Esko, J., and Zhang, L. (1996) Curr. Opin. Struct. Biol. 6, 663-670
46. The, I., Bellaiche, Y., and Perrimon, N. (1999) Mol. Cell 4, 633-639
47. Kramer, K. L., and Yost, H. J. (2003) Annu. Rev. Genet. 37, 461-484