Internalization of biotinylated compounds into cancer cells is promoted by a molecular Trojan horse based upon core streptavidin and clostridial C2 toxin

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 3, 2011, Pages 263-273

  Fahrer, Jörg ^a   Funk, Joschua ^a   Lillich, Maren ^a   Barth, Holger ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

Biotin; C2 toxin; Cancer cells; Cargo; Delivery system; Streptavidin

Indexed keywords

BIOCYTIN; BIOTIN; C2IN STV13 FUSION PROTEIN; HYBRID PROTEIN; STAUROSPORINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; BIOTINYLATION; CANCER CELL; CELL PROLIFERATION; CELL VIABILITY; CYTOSOL; CYTOTOXICITY; DNA SEQUENCE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; BIOTIN; BIOTINYLATION; BOTULINUM TOXINS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSOL; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; ENDOSOMES; FLUORESCENT DYES; HELA CELLS; HEP G2 CELLS; HUMANS; JURKAT CELLS; LYSINE; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; STREPTAVIDIN; VERO CELLS;

EID: 79954571598     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0585-7     Document Type: Article

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