Simultaneous determination of O6-methyl-2′-deoxyguanosine, 8-oxo-7,8-dihydro-2′-deoxyguanosine, and 1,N6-etheno-2′- deoxyadenosine in DNA using on-line sample preparation by HPLC column switching coupled to ESI-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 830, Issue 2, 2006, Pages 255-261

  Brink, Andreas ^a   Lutz, Ursula ^a   Völkel, Wolfgang ^a   Lutz, Werner K ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Background DNA damage; DNA adducts; Lipid peroxidation; Mass spectrometry; Methylation; Oxidation; Oxidative stress; Rat liver

Indexed keywords

BIOLOGICAL MATERIALS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVING SYSTEMS STUDIES; MASS SPECTROMETRY; OXIDATION; SYNTHESIS (CHEMICAL);

BACKGROUND DNA DAMAGE; DNA ADDUCTS; LIPID PEROXIDATION; METHYLATION; OXIDATIVE STRESS; RAT LIVER;

DNA;

1,N 6 ETHENO 2' DEOXYADENOSINE; 8 HYDROXYDEOXYGUANOSINE; DEOXYADENOSINE DERIVATIVE; DEOXYGUANOSINE DERIVATIVE; O 6 METHYL 2' DEOXYGUANOSINE; PROMUTAGEN; UNCLASSIFIED DRUG; 1,N(6) ETHENODEOXYADENOSINE; 1,N(6)-ETHENODEOXYADENOSINE; 8 OXO 7 HYDRODEOXYGUANOSINE; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE; DNA; DRUG DERIVATIVE; O(6) METHYL 2' DEOXYGUANOSINE; O(6)-METHYL-2'-DEOXYGUANOSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; DNA ADDUCT; DNA DAMAGE; DNA DETERMINATION; DNA METHYLATION; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS; TANDEM MASS SPECTROMETRY; ANIMAL; CHEMISTRY; INSTRUMENTATION; ISOLATION AND PURIFICATION; METHODOLOGY; REPRODUCIBILITY;

ANIMALIA;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYADENOSINES; DEOXYGUANOSINE; DNA; DNA ADDUCTS; RATS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 30444432956     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.10.046     Document Type: Article

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