Effect of Methylphenidate on Motivation in Children With Attention-Deficit/Hyperactivity Disorder

Experimental and Clinical Psychopharmacology

Volumn 19, Issue 2, 2011, Pages 145-153

  Chelonis, John J ^a   Johnson, Teresa A ^b   Ferguson, Sherry A ^a   Berry, Kimberly J ^a   Kubacak, Brian ^b   Edwards, Mark C ^b   Paule, Merle G ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b ARKANSAS CHILDREN S HOSPITAL   (United States)

Author keywords

Attention Deficit Hyperactivity Disorder; Children; Methylphenidate; Motivation; Progressive ratio

Indexed keywords

METHYLPHENIDATE;

ANALYTIC METHOD; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; MOTIVATION; PROGRESSIVE RATIO TASK; SCHOOL CHILD;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; HUMANS; METHYLPHENIDATE; MOTIVATION;

EID: 79954484121     PISSN: 10641297     EISSN: 19362293     Source Type: Journal    
DOI: 10.1037/a0022794     Document Type: Article

References (66)

1. Aberman J.E., Ward S.J., Salamone J.D. Effects of dopamine antagonists and accumbens dopamine depletions on time-constrained progressive-ratio performance. Pharmacology, Biochemistry, and Behavior 1998, 61(4):341-348.
2. Antrop I., Stock P., Verté S., Wiersema J.R., Baeyens D., Roeyers H. ADHD and delay aversion: The influence of non-temporal stimulation on choice for delayed rewards. Journal of Child Psychology and Psychiatry 2006, 47(11):1152-1158.
3. Baldwin R.L., Chelonis J.J., Flake R.A., Edwards M.C., Feild C.R., Meaux J.B., Paule M.G. Effect of methylphenidate on time perception in children with Attention-Deficit/Hyperactivity Disorder. Experimental and Clinical Psychopharmacology 2004, 12(1):57-64.
4. Barbano M., Le Saux M., Cador M. Involvement of dopamine and opioids in the motivation to eat: Influence of palatability, homeostatic state, and behavioral paradigms. Psychopharmacology 2009, 203(3):475-487.
5. Barkley R.A. Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD. Psychological Bulletin 1997, 121(1):65-94.
6. Barkley R.A., Fischer M., Edelbrock C., Smallish L. The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. Journal of the American Academy of Child & Adolescent Psychiatry 1990, 29(4):546-557.
7. Barkley R.A., Koplowitz S., Anderson T., McMurray M.B. Sense of time in children with ADHD: Effects of duration, distraction, and stimulant medication. Journal of the International Neuropsychological Society 1997, 3(4):359-369.
8. Baron A., Derenne A. Progressive-ratio schedules: Effects of later schedule requirements on earlier performances. Journal of the Experimental Analysis of Behavior 2000, 73(3):291-304.
9. Bedard A.C., Ickowicz A., Logan G.D., Hogg-Johnson S., Schachar R., Tannock R. Selective inhibition in children with Attention-Deficit Hyperactivity Disorder off and on stimulant medication. Journal of Abnormal Child Psychology 2003, 31(3):315-327.
10. Bezzina G., den Boon F.S., Hampson C.L., Cheung T.H., Body S., Bradshaw C.M., Deakin J.F.W. Effect of quinolinic acid-induced lesions of the nucleus accumbens core on performance on a progressive ratio schedule of reinforcement: Implications for inter-temporal choice. Psychopharmacology 2008, 197(2):339-350.
11. Biederman J., Seidman L.J., Petty C.R., Fried R., Doyle A.E., Cohen D.R., Faraone S.V. Effects of stimulant medication on neuropsychological functioning in young adults with attention-deficit/hyperactivity disorder. Journal of Clinical Psychiatry 2008, 69(7):1150-1156.
12. Carlson C.L., Mann M., Alexander D.K. Effects of reward and response cost on the performance and motivation of children with ADHD. Cognitive Therapy and Research 2000, 24(1):87-98.
13. Carlson C.L., Tamm L. Responsiveness of children with attention deficit-hyperactivity disorder to reward and response cost: Differential impact on performance and motivation. Journal of Consulting and Clinical Psychology 2000, 68(1):73-83.
14. Chelonis J.J., Edwards M.C., Schulz E.G., Baldwin R., Blake D.J., Wenger A., Paule M.G. Stimulant medication improves recognition memory in children diagnosed with attention-deficit/hyperactivity disorder. Experimental and Clinical Psychopharmacology 2002, 10(4):400-407.
15. Conners K. Conners' Rating Scales-Revised 1997, Multi-Health Systems, Toronto, Canada.
16. Crossman E.K. Pause relationships in multiple and chained fixed-ratio schedules. Journal of Experimental Analysis of Behavior 1968, 48:395-406.
17. DeVito E.E., Blackwell A.D., Clark L., Kent L., Dezsery A.M., Turner D.C., Sahakian B.J. Methylphenidate improves response inhibition but not reflection-impulsivity in children with attention deficit hyperactivity disorder (ADHD). Psychopharmacology 2009, 202(1-3):531-539.
18. DiScala C., Lescohier I., Barthel M., Li G. Injuries to children with Attention Deficit Hyperactivity Disorder. Pediatrics 1998, 102(6):1415.
19. Douglas V.I., Parry P.A. Effects of reward on delayed reaction time task performance of hyperactive children. Journal of Abnormal Child Psychology 1983, 11(2):313-326.
20. Douglas V.I., Parry P.A. Effects of reward and nonreward on frustration and attention in attention deficit disorder. Journal of Abnormal Child Psychology 1994, 22(3):281-302.
21. Ferguson S.A., Paule M.G. Progressive ratio performance varies with body weight in rats. Behavioural Processes 1997, 40(2):177-182.
22. Freibergs V., Douglas V.I. Concept learning in hyperactive and normal children. Journal of Abnormal Psychology 1969, 74(3):388-395.
23. Gadow K.D., Sprafkin J. Child Symptom Inventory-4: Norms manual 1997, Checkmate Plus, Stony Brook, NY.
24. Gittelman R., Mannuzza S., Shenker R., Bonagura N. Hyperactive boys almost grown up: I. Psychiatric status. Archives of General Psychiatry 1985, 42(10):937-947.
25. Haenlein M., Caul W.F. Attention Deficit Disorder with Hyperactivity: A specific hypothesis of reward dysfunction. Journal of the American Academy of Child & Adolescent Psychiatry 1987, 26(3):356-362.
26. Hamill S., Trevitt J.T., Nowend K.L., Carlson B.B., Salamone J.D. Nucleus accumbens dopamine depletions and time-constrained progressive ratio performance: Effects of different ratio requirements. Pharmacology, Biochemistry and Behavior 1999, 64(1):21-27.
27. Hodos W. Progressive ratio as a measure of reward strength. Science 1961, 134(3483):943-944.
28. Hodos W., Kalman G. Effects of increment size and reinforcer volume on progressive ratio performance. Journal of the Experimental Analysis of Behavior 1963, 6(3):387-392.
29. Kaufman A.S., Kaufman N.L. Kaufman Brief Intelligence Test 1990, American Guidance Services, Circle Pines, MN.
30. Keesey R.E., Goldstein M.D. Use of progressive fixed-ratio procedures in the assessment of intracranial reinforcement. Journal of the Experimental Analysis of Behavior 1968, 11(3):293-301.
31. Kempton S., Vance A., Maruff P., Luk E., Costin J., Pantelis C. Executive function and Attention Deficit Hyperactivity Disorder: Stimulant medication and better executive function performance in children. Psychological Medicine: A Journal of Research in Psychiatry and the Allied Sciences 1999, 29(3):527-538.
32. Kerns K.A., McInerney R.J., Wilde N.J. Time reproduction, working memory, and behavioral inhibition in children with ADHD. Child Neuropsychology 2001, 7(1):21-31.
33. Killeen P.R., Posadas-Sanchez D., Johansen E., Thrailkill E.A. Progressive ratio schedules of reinforcement. Journal of Experimental Psychology: Animal Behavior Processes 2009, 35(1):35-50.
34. Konrad K., Gauggel S., Manz A., Schöll M. Lack of inhibition: A motivational deficit in children with attention deficit/hyperactivity disorder and children with traumatic brain injury. Child Neuropsychology 2000, 6(4):286-296.
35. Luman M., Oosterlaan J., Sergeant J.A. The impact of reinforcement contingencies on AD/HD: A review and theoretical appraisal. Clinical Psychology Review 2005, 25(2):183-213.
36. Mayes R., Bagwell C., Erkulwater J. ADHD and the rise in stimulant use among children. Harvard Review of Psychiatry 2008, 16(3):151-166.
37. McInerney R.J., Kerns K.A. Time reproduction in children with ADHD: Motivation matters. Child Neuropsychology 2003, 9(2):91-108.
38. Milberger S., Biederman J., Faraone S.V., Chen L., Jones J. Further evidence of an association between attention-deficit/hyperactivity disorder and cigarette smoking: Findings from a high-risk sample of siblings. The American Journal on Addictions 1997, 6(3):205-217.
39. Mintz D.E., Mourer D.J., Gofseyeff M. Sequential effects in fixed-ratio postreinforcement pause duration. Psychonomic Science 1967, 9:387-388.
40. Neef N.A., Marckel J., Ferreri S.J., Bicard D.F., Endo S., Aman M.G., Armstrong N. Behavioral Assessment of Impulsivity: A comparison of children with and without Attention Deficit Hyperactivity Disorder. Journal of Applied Behavior Analysis 2005, 38(1):23-37.
41. O'Driscoll G.A., Dépatie L., Holahan A.V., Savion-Lemieux T., Barr R.G., Jolicoeur C., Douglas V.I. Executive functions and methylphenidate response in subtypes of Attention-Deficit/Hyperactivity Disorder. Biological Psychiatry 2005, 57(11):1452-1460.
42. Parry P.A., Douglas V.I. Effects of reinforcement on concept identification in hyperactive children. Journal of Abnormal Child Psychology 1983, 11(2):327-340.
43. Pastor P.N., Reuben C.A. Diagnosed Attention Deficit Hyperactivity Disorder and learning disability: United States, 2004-2006. National Center for Health Statistics. Vital Health Stat 2008, 10(237).
44. Paule M.G., Chelonis J.J., Buffalo E.A., Blake D.J., Casey P.H. Operant test battery performance in children: Correlation with IQ. Neurotoxicology and Teratology 1999, 21(3):223-230.
45. Paule M.G., Cranmer J.M., Wilkins J.D., Stern H.P., Hoffman E.L. Quantitation of complex brain function in children: Preliminary evaluation using a nonhuman primate behavioral test battery. Neurotoxicology 1988, 9(3):367-378.
46. Pennington B.F., Ozonoff S. Executive functions and developmental psychopathology. Journal of Child Psychology and Psychiatry 1996, 37(1):51-87.
47. Pliszka S.R., Greenhill L.L., Crimson M.L., Sedillo A., Carlson C., Conners C.K., Toprac M.G. The Texas Children's Medication Algorithm Project: Report of the Texas Consensus Conference Panel on medication treatment of Childhood Attention-Deficit/Hyperactivity Disorder. Part I. Journal of the American Academy of Child & Adolescent Psychiatry 2000, 39(7):908-919.
48. Polanczyk G., deLima M.S., Horta B.L., Biederman J., Rohde L.A. The worldwide prevalence of ADHD: A systematic review and metaregression analysis. American Journal of Psychiatry 2007, 164(6):942-948.
49. Rapport M. Hyperactivity and frustration: The influence of control over and size of rewards in delaying gratification. Journal of Abnormal Child Psychology 1986, 14(2):191-204.
50. Richardson N.R., Roberts D.C.S. Progressive ratio schedules in drug self-administration studies in rats- a method to evaluate reinforcing efficacy. Journal of Neuroscience Methods 1996, 66(1):1-11.
51. Roane H.S. On the applied use of progressive-ratio schedules of reinforcement. Journal of Applied Behavior Analysis 2008, 41(2):155-161.
52. Roberts D.C. Breaking points on a progressive ratio schedule reinforced by intravenous apomorphine increase daily following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacology, Biochemistry and Behavior 1989, 32(1):43-47.
53. Salamone J.D., Correa M., Mingote S.M., Weber S.M., Farrar A.M. Nucleus accumbens dopamine and the forebrain circuitry involved in behavioral activation and effort-related decision making: Implications for understanding anergia and psychomotor slowing in depression. Current Psychiatry Reviews 2006, 2(2):267-280.
54. Schweitzer J.B., Sulzer-Azaroff B. Self-control in boys with attention deficit hyperactivity disorder: Effects of added stimulation and time. Journal of Child Psychology and Psychiatry 1995, 36(4):671-686.
55. Shiels K., Hawk L.W., Reynolds B., Mazzullo R., Rhodes J.J., Pelham W.E., Gangloff B.P. Effects of methylphenidate on discounting of delayed rewards in Attention Deficit/Hyperactivity Disorder. Experimental and Clinical Psychopharmacology 2009, 17(5):291-301.
56. Skjoldager P., Pierre P., Mittleman G. Reinforcer magnitude and progressive ratio responding in the rat: Effects of increased effort, prefeeding, and extinction. Learning and Motivation 1993, 24(3):303-343.
57. Solanto M.V., Abikoff H., Sonuga-Barke E., Schachar R., Logan G.D., Wigal T., Turkel E. The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: A Suppl. to the NIMH Multimodal Treatment Study of AD/HD. Journal of Abnormal Child Psychology 2001, 29(3):215-228.
58. Sonuga-Barke E., Taylor E., Sembi S., Smith J. Hyperactivity and delay aversion: I. The effect of delay on choice. Journal of Child Psychology and Psychiatry 1992, 33(2):387-398.
59. Spencer S.V., Hawk L.W., Richards J.B., Shiels K., Pelham W.E., Waxmonsky J.G. Stimulant treatment reduced lapses in attention among children on intra-individual response time distributions. Journal of Abnormal Child Psychology 2009, 37:805-816.
60. Tripp G., Alsop B. Sensitivity to reward delay in children with attention deficit hyperactivity disorder (ADHD). Journal of Child Psychology and Psychiatry 2001, 42(5):691-698.
61. Tripp G., Wickens J.R. Dopamine transfer deficit: A neurobiological theory of altered reinforcement mechanisms in ADHD. Journal of Child Psychology and Psychiatry 2008, 49(7):691-704.
62. Volkow N.D., Fowler J.S., Wang G., Ding Y., Gatley S.J. Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: Results from imaging studies. European Neuropsychopharmacology 2002, 12(6):557-566.
63. Volkow N.D., Wang G., Kollins S.H., Wigal T.L., Newcorn J.H., Telang F., Swanson J.M. Evaluating dopamine reward pathway in ADHD: Clinical implications. JAMA: Journal of the American Medical Association 2009, 302(10):1084-1091.
64. Wigal T., Swanson J.M., Regino R., Lerner M.A., Soliman I., Steinhoff K., Wigal S.B. Stimulant medications for the treatment of ADHD: Efficacy and limitations. Mental Retardation and Developmental Disabilities Research Reviews 1999, 5(3):215-224.
65. Wilkison P.C., Kircher J.C., McMahon W.M., Sloane H.N. Effects of methylphenidate on reward strength in boys with Attention-Deficit Hyperactivity Disorder. Journal of the American Academy of Child & Adolescent Psychiatry 1995, 34(7):897-901.
66. Wise R.A. Dopamine, learning and motivation. Nature Reviews Neuroscience 2004, 5(6):483-494.