Methylphenidate improves response inhibition but not reflection-impulsivity in children with attention deficit hyperactivity disorder (ADHD)

Psychopharmacology

Volumn 202, Issue 1-3, 2009, Pages 531-539

  Devito, Elise E ^a   Blackwell, Andrew D ^a   Clark, Luke ^b,c   Kent, Lindsey ^a,d   Dezsery, Anna Maria ^d   Turner, Danielle C ^a,c   Aitken, Michael R F ^b,c   Sahakian, Barbara J ^a,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UK   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

ADHD; Cognition; Cognitive enhancement; Decision making; Disinhibition; Impulsivity; Methylphenidate; Reflection impulsivity; Response inhibition; Stop signal

Indexed keywords

METHYLPHENIDATE; PLACEBO;

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DECISION MAKING; DOUBLE BLIND PROCEDURE; HUMAN; IMPULSIVENESS; INFORMATION SAMPLING TASK; LATENT PERIOD; MALE; MENTAL TASK; PRIORITY JOURNAL; SCHOOL CHILD; STOP SIGNAL TASK; TASK PERFORMANCE;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; CROSS-OVER STUDIES; DECISION MAKING; DOUBLE-BLIND METHOD; HUMANS; IMPULSIVE BEHAVIOR; INHIBITION (PSYCHOLOGY); MALE; METHYLPHENIDATE; NEUROPSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE; QUESTIONNAIRES;

EID: 59449099227     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-008-1337-y     Document Type: Article

References (40)

1. Achenbach TM (1991) Integrative guide to the 1991 CBCL/4-18, YSR, and TRF profiles. Department of Psychology, University of Vermont, Burlington, VT
2. APA (1994) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
3. AR Aron RA Poldrack 2005 The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder Biol Psychiatry 57 1285 1292
4. AR Aron JH Dowson BJ Sahakian TW Robbins 2003 Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder Biol Psychiatry 54 1465 1468
5. RA Barkley 1997 Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD Psychol Bull 121 65 94
6. CW Berridge DM Devilbiss ME Andrzejewski AF Arnsten AE Kelley B Schmeichel C Hamilton RC Spencer 2006 Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function Biol Psychiatry 60 1111 1120
7. J Block JH Block DM Harrington 1974 Some misgivings about the matching familiar figures test as a measure of reflection impulsivity Dev Psychol 10 611 632
8. RT Brown EK Sleator 1979 Methylphenidate in hyperkinetic children: differences in dose effects on impulsive behaviour Pediatrics 64 408 411
9. S Chamberlain BJ Sahakian 2006 Attention deficit hyperactivity disorder has serious and immediate implications Educ J 94 35 37
10. T Clark C Feehan C Tinline P Vostanis 1999 Autistic symptoms in children with attention deficit-hyperactivity disorder Eur Child Adolesc Psychiatry 8 50 55
11. L Clark TW Robbins KD Ersche BJ Sahakian 2006 Reflection impulsivity in current and former substance users Biol Psychiatry 60 515 522
12. Clark L, Roiser JP, Robbins TW, Sahakian BJ (2008) Disrupted 'reflection' impulsivity in cannabis users but not current or former ecstasy users. J Psychopharmacol (in press)
13. Conners C (1989) Conners rating scales: CPRS-39, CTRS-39. Multi-Health Systems, North Tonawanda, NY
14. EE DeVito AD Blackwell L Kent KD Ersche L Clark CH Salmond AM Dezsery BJ Sahakian 2008 The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder Biol Psychiatry 64 636 639
15. DM Drake 1970 Perceptual correlates of impulsive and reflective behaviour Dev Psychol 2 202 214
16. WP Dunlap JM Cortina JB Vaslow MJ Burke 1996 Meta-analysis of experiments with matched groups or repeated measures designs Psychol Methods 1 170 177
17. JL Evenden 1999 Varieties of impulsivity Psychopharmacology (Berl) 146 348 61
18. SBG Eysenck 1981 Impulsiveness and antisocial behaviour in children Curr Psychol Res 1 31 37
19. JM Halperin JH Newcorn K Matier G Bedi S Hall V Sharma 1995 Impulsivity and the initiation of fights in children with disruptive behavior disorders J Child Psychol Psychiatry 36 1199 1211
20. J Kagan 1966 Reflection-impulsivity: the generality and dynamics of conceptual tempo J Abnorm Psychology 71 17 24
21. K Konrad T Gunther C Hanisch B Herpertz-Dahlmann 2004 Differential effects of methylphenidate on attentional functions in children with attention-deficit/hyperactivity disorder J Am Acad Child Adolesc Psych 43 191 198
22. M Lijffijt EM Bekker EH Quik J Bakker JL Kenemans MN Verbaten 2004 Differences between low and high trait impulsivity are not associated with differences in inhibitory motor control J Atten Disord 8 25 32
23. M Lijffijt JL Kenemans A ter Wal EH Quik C Kemner H Westenberg MN Verbaten H van Engeland 2006 Dose-related effect of methylphenidate on stopping and changing in children with attention-deficit/hyperactivity disorder Eur Psychiatry 21 544 547
24. GD Logan 1994
25. GD Logan WB Cowan KA Davis 1984 On the ability to inhibit simple and choice reaction time responses: a model and a method J Exp Psychol Hum Percept Perform 10 276 291
26. SB Messer 1976 Reflection-impulsivity: a review Psychol Bull 83 1026 1052
27. JT Nigg 2000 On inhibition/disinhibition in developmental psychopathology: views from cognitive and personality psychology and a working inhibition taxonomy Psychol Bull 126 220 246
28. A Osman S Kornblum DE Meyer 1990 Does motor programming necessitate response execution? J Exp Psychol Hum Percept Perform 16 183 198
29. B Reynolds 2006 A review of delay-discounting research with humans: relations to drug use and gambling Behav Pharmacol 17 651 667
30. HE Rosvold JM Delgado 1956 The effect on delayed-alternation test performance of stimulating or destroying electrically structures within the frontal lobes of the monkey's brain J Comp Physiol Psychol 49 365 372
31. J Sandoval 1977 The measurement of the hyperkinetic syndrome in children Rev Educ Res 47 293 318
32. A Scheres M Dijkstra E Ainslie J Balkan B Reynolds E Sonuga-Barke FX Castellanos 2006 Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptoms Neuropsychologia 44 2092 2103
33. JB Schweitzer B Sulzer-Azaroff 1995 Self-control in boys with attention deficit hyperactivity disorder: effects of added stimulation and time J Child Psychol Psychiatry 36 671 686
34. Solanto MV, Arnsten AFT, Castellanos FX (2001) Stimulant drugs and ADHD. Oxford University Press, Oxford
35. EJ Sonuga-Barke E Taylor S Sembi J Smith 1992 Hyperactivity and delay aversion-I. The effect of delay on choice J Child Psychol Psychiatry 33 387 398
36. AC Swann JM Bjork FG Moeller DM Dougherty 2002 Two models of impulsivity: relationship to personality traits and psychopathology Biol Psychiatry 51 988 994
37. R Tannock RJ Schachar RP Carr D Chajczyk GD Logan 1989 Effects of methylphenidate on inhibitory control in hyperactive children J Abnorm Child Psychol 17 473 491
38. JV Taylor Tavares L Clark DM Cannon K Erickson WC Drevets BJ Sahakian 2007 Distinct profiles of neurocognitive function in unmedicated unipolar depression and bipolar II depression Biol Psychiatry 62 917 924
39. ND Volkow JS Fowler G Wang Y Ding SJ Gatley 2002 Mechanism of action of methylphenidate: insights from PET imaging studies J Atten Disord 6 Suppl 1 S31 S43
40. A Wood L Kroll A Moore R Harrington 1995 Properties of the mood and feelings questionnaire in adolescent psychiatric outpatients: a research note J Child Psychol Psychiatry 36 327 334