Solamargine, a steroidal alkaloid glycoside, induces oncosis in human K562 leukemia and squamous cell carcinoma KB cells

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 4, 2011, Pages 813-821

  Sun, Lingmei ^a   Zhao, Ying ^a   Yuan, Huiqing ^a   Li, Xia ^b   Cheng, Aixia ^a   Lou, Hongxiang ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Actin; Alkaloidal saponins; Membrane blebs; Microtubule; Solamargine

Indexed keywords

EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; LACTATE DEHYDROGENASE; MACROGOL; MULTIDRUG RESISTANCE PROTEIN 1; PROPIDIUM IODIDE; SOLAMARGINE;

ARTICLE; CALCIUM CELL LEVEL; CELL DAMAGE; CELL MEMBRANE PERMEABILITY; CELL PERMEABILIZATION; CELL STRAIN K 562; CELL STRAIN KB; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME RELEASE; HUMAN; HUMAN CELL; LEUKEMIA CELL; ONCOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLISTER; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL MEMBRANE; CYTOSKELETON; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; K562 CELLS; KB CELLS; L-LACTATE DEHYDROGENASE; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; SOLANACEOUS ALKALOIDS; TIME FACTORS;

EID: 79954448902     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1387-9     Document Type: Article

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