Cyclooxygenase-2 contributes to functional changes seen on experimental hemorrhagic cystitis induced by ifosfamide in rat urinary bladder

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 4, 2011, Pages 935-943

  MacEdo, Francisco Y B ^a   Mourão, Lívia T C ^a   Palheta Jr , Raimundo C ^a   Jucá, Davi M ^a   Lima Jr , Roberto C P ^a   De Sá C Neto, José ^a   Magalhães, Pedro J C ^a   Santos, Armênio A ^a   Souza, Marcellus H L P ^a   Brito, Gerly A C ^a   Ribeiro, Ronaldo A ^a,b  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b Instituto do Cancer do Ceara   (Brazil)

Author keywords

Cyclooxygenase 2; Cystitis; Etoricoxib; Ifosfamide; Mesna

Indexed keywords

CARBACHOL; CYCLOOXYGENASE 2; ETORICOXIB; HOLOXANE; IFOSFAMIDE; INDOMETACIN; MESNA; POTASSIUM CHLORIDE; PROSTAGLANDIN E1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER PRESSURE; CONTROLLED STUDY; CYSTOMETRY; HEMORRHAGIC CYSTITIS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE CONTRACTILITY; URINARY FREQUENCY;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYSTITIS; DINOPROSTONE; DISEASE MODELS, ANIMAL; HEMORRHAGE; IFOSFAMIDE; INFLAMMATION; MALE; MESNA; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; URINATION;

EID: 79954438745     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1392-z     Document Type: Article

References (25)

1. D Higgs C Nagy LH Einhorn 1989 Ifosfamide: a clinical review Semin Oncol Nurs 5 70 77 2657933 10.1016/0749-2081(89)90084-3 1:STN:280:DyaL1M3ms1ajsA%3D%3D
2. GP Kaijser A Korst JH Beijnen A Bult WJ Underberg 1993 The analysis of ifosfamide and its metabolites Anticancer Res 13 1311 1324 8239501 1:CAS:528:DyaK2cXktVSjsb4%3D (Pubitemid 23334755)
3. JP Kehrer SS Biswal 2000 The molecular effects of acrolein Toxicol Sci 57 6 15 10966506 10.1093/toxsci/57.1.6 1:CAS:528:DC%2BD3cXmslyls7g%3D
4. TJ Stillwell RC Benson 1988 Cyclophosphamide-induced hemorrhagic cystitis: a review of 100 patients Cancer 61 451 457 3338015 10.1002/1097-0142(19880201)61:3<451::AID-CNCR2820610308>3.0.CO;2-G 1:STN:280:DyaL1c7gvFahsw%3D%3D (Pubitemid 18039357)
5. RA Ribeiro HC Freitas MC Campos CC Santos FC Figueiredo GA Brito FQ Cunha 2002 Tumor necrosis factor-alpha and interleukin-1beta mediate the production of nitric oxide involved in the pathogenesis of ifosfamide induced hemorrhagic cystitis in mice J Urol 167 2229 2234 11956484 10.1016/S0022-5347(05)65134-8 1:CAS:528:DC%2BD38XjtlWju70%3D (Pubitemid 34309711)
6. MM Vieira GA Brito JN Belarmino-Filho FY Macedo EA Nery FQ Cunha RA Ribeiro 2003 Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis Int J Urol 10 595 602 14633084 10.1046/j.1442-2042.2003.00709.x 1:CAS:528:DC%2BD2cXhvFKjsA%3D%3D (Pubitemid 37506135)
7. CK Batista JM Mota ML Souza BT Leitão MH Souza GA Brito FQ Cunha RA Ribeiro 2007 Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis Cancer Chemother Pharmacol 59 71 77 16708234 10.1007/s00280-006-0248-z 1:CAS:528:DC%2BD28Xht1entLzP (Pubitemid 44796104)
8. FY Macedo F Baltazar PR Almeida F Távora FV Ferreira FC Schmitt GA Brito RA Ribeiro 2008 Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats J Cancer Res Clin Oncol 134 19 27 17638016 10.1007/s00432-007-0237-6 1:CAS:528:DC%2BD2sXht1KrurvM (Pubitemid 350064247)
9. FY Macedo F Baltazar LC Mourao 2008 Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis Exp Toxicol Pathol 59 425 430 18234483 10.1016/j.etp.2007.10.010 1:CAS:528:DC%2BD1cXmsVyltLw%3D
10. HS Büyüknacar EK Kumcu C Göçmen S Onder 2008 Effect of phosphodiesterase type 4 inhibitor rolipram on cyclophosphamide-induced cystitis in rats Eur J Pharmacol 31 293 299 10.1016/j.ejphar.2008.02.022
11. YC Chuang N Yoshimura CC Huang M Wu PH Chiang MB Chancellor 2009 Intravesical botulinum toxin A administration inhibits COX-2 and EP4 expression and suppresses bladder hyperactivity in cyclophosphamide-induced cystitis in rats Eur Urol 56 159 166 18514386 10.1016/j.eururo.2008.05.007 1:CAS:528:DC%2BD1MXhsVamsbnP
12. E Bressan CR Tonussi 2008 Antiinflammatory effects of etoricoxib alone and combined with NSAIDs in LPS-induced reactive arthritis Inflamm Res 57 586 592 19109739 10.1007/s00011-008-8029-2 1:CAS:528:DC%2BD1cXhsFChtLbF
13. S Matsuura JW Downie 2000 Effect of anesthetics on reflex micturition in the chronic cannula-implanted rat Neurourol Urodyn 19 87 99 10602250 10.1002/(SICI)1520-6777(2000)19:1<87::AID-NAU9>3.0.CO;2-O 1:CAS:528:DC%2BD3cXlt12lsg%3D%3D (Pubitemid 30038856)
14. VY Hu S Malley A Dattilio JB Folsom P Zvara MA Vizzard 2003 COX-2 and prostanoid expression in micturition pathways after cyclophosphamide-induced cystitis in the rat Am J Physiol Regul Integr Comp Physiol 284 R574 R585 12388444 1:CAS:528:DC%2BD3sXhtlOqt7c%3D
15. CA Maggi 1992 Prostanoids as local modulators of reflex micturition Pharmacol Res 25 13 20 1738753 10.1016/S1043-6618(05)80059-3 1:CAS:528:DyaK38XhsVeqtb8%3D
16. O Ishizuka A Mattiasson KE Andersson 1995 Prostaglandin E2-induced bladder hyperactivity in normal, conscious rats: involvement of tachykinins? J Urol 153 2034 2038 7752389 10.1016/S0022-5347(01)67397-X 1:STN:280: DyaK2M3ntFyhug%3D%3D
17. MI Bultitude NH Hills KED Shuttleworth 1976 Clinical and experimental studies on the action of prostaglandins and their synthesis inhibitors on detrusor muscle in vitro and in vivo Br J Urol 48 631 637 1016837 10.1111/j.1464-410X.1976.tb06711.x 1:CAS:528:DyaE2sXktVSmt7Y%3D (Pubitemid 8031581)
18. N Yoshimura WC De Groat 1999 Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation J Neurosci 19 4644 4653 10341262 1:CAS:528:DyaK1MXjsFags7s%3D (Pubitemid 29241112)
19. A Lecci LA Birder S Meini RM Catalioto M Tramontana S Giuliani M Criscuoli CA Maggi 2000 Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis in rats Br J Pharmacol 130 331 338 10807670 10.1038/sj.bjp.0703309 1:CAS:528: DC%2BD3cXjsl2murw%3D (Pubitemid 30261043)
20. P Lagos G Ballejo 2004 Role of spinal nitric oxide synthase-dependent processes in the initiation of the micturition hyperreflexia associated with cyclophosphamide-induced cystitis Neuroscience 125 663 670 15099680 10.1016/j.neuroscience.2003.10.048 1:CAS:528:DC%2BD2cXjt1antbk%3D (Pubitemid 38510176)
21. MH Mok GE Knight PL Andrews CH Hoyle G Burnstock 2000 The effects of cyclophosphamide on neurotransmission in the urinary bladder of Suncus murinus, the house musk shrew J Auton Nerv Syst 80 130 136 10785278 10.1016/S0165- 1838(00)00085-0 1:CAS:528:DC%2BD3cXislartbw%3D (Pubitemid 30227497)
22. D Giglio P Aronsson L Eriksson G Tobin 2007 In vitro characterization of parasympathetic and sympathetic responses in cyclophosphamide-induced cystitis in the rat Basic Clin Pharmacol Toxicol 100 96 108 17244258 10.1111/j.1742-7843. 2007.00014.x 1:CAS:528:DC%2BD2sXjt1Gkt7w%3D (Pubitemid 46146713)
23. JA Mitchell P Akarasereenont C Thiemermann RJ Flower JR Vane 1993 Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase Proc Natl Acad Sci USA 90 11693 11697 8265610 10.1073/pnas.90.24.11693 1:CAS:528:DyaK2cXmvFSltw%3D%3D (Pubitemid 24008705)
24. D Riendeau MD Percival C Brideau S Charleson D Dubé D Ethier JP Falgueyret RW Friesen R Gordon G Greig J Guay J Mancini M Ouellet E Wong L Xu S Boyce D Visco Y Girard P Prasit R Zamboni IW Rodger M Gresser AW Ford-Hutchinson RN Young CC Chan 2001 Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2 J Pharmacol Exp Ther 296 558 566 11160644 1:CAS:528:DC%2BD3MXosleisg%3D%3D (Pubitemid 32112486)
25. A Lecci S Meini R Patacchini M Tramontana S Giuliani M Criscuoli CA Maggi 1999 Effect of dexamethasone on cyclophosphamide-induced cystitis in rats: lack of relation with bradykinin B1 receptor-mediated motor responses Eur J Pharmacol 369 99 106 10204687 10.1016/S0014-2999(99)00052-7 1:CAS:528: DyaK1MXhvVCmt70%3D (Pubitemid 29129546)