Fused heterocyclic amido compounds as anti-hepatitis C virus agents

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 8, 2011, Pages 2675-2687

  Aoyama, Hiroshi ^a   Sugita, Kazuyuki ^a   Nakamura, Masahiko ^a   Aoyama, Atsushi ^a   Salim, Mohammed T A ^b   Okamoto, Mika ^b   Baba, Masanori ^b   Hashimoto, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

1,3 Dioxolyl; Anti HCV agent; Hepatitis C virus; Methoxy; Phenanthridine

Indexed keywords

2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 5 (2 METHOXYETHYL)PHENANTHRIDIN 6(5H) ONE; 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 5 (2 NAPHTHYLMETHYL)PHENANTHRIDIN 6(5H) ONE; 2 (4 BUTYLAMINO 2 FLUOROPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 2 (4 BUTYLAMINO 2 METHOXYPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 2 (4 BUTYLAMINO 2 METHYLPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 2 (4 BUTYLAMINO 3 FLUOROPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 2 (4 BUTYLAMINO 3 METHOXYPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 2 (4 BUTYLAMINO 3 METHYLPHENYL) 1,1,1,3,3,3 HEXAFLUOROPROPAN 2 OL; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 1,4 DIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 1,4,8 TRIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 10 METHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3 FLUOROPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3 METHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3,4 DIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3,4,8 TRIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3,8 DIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 4 FLUOROPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 4 METHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 4,8 DIMETHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 7 METHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 8 METHOXYPHENANTHRIDIN 6(5H) ONE; 5 BUTYL 2 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 9 METHOXYPHENANTHRIDIN 6(5H) ONE; HETEROCYCLIC COMPOUND; N BUTYL N [2 FLUORO 4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL)PHENYL] 2 IODOBENZAMIDE; N BUTYL N [3 FLUORO 4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL)PHENYL] 2 IODOBENZAMIDE; N BUTYL N [4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 2 METHOXYPHENYL] 2 IODOBENZAMIDE; N BUTYL N [4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 2 METHYLPHENYL] 2 IODOBENZAMIDE; N BUTYL N [4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3 METHOXYPHENYL] 2 IODOBENZAMIDE; N BUTYL N [4 (1,1,1,3,3,3 HEXAFLUORO 2 HYDROXYPROPAN 2 YL) 3 METHYLPHENYL] 2 IODOBENZAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS C; NONHUMAN; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION;

ANTIVIRAL AGENTS; HEPACIVIRUS; HETEROCYCLIC COMPOUNDS; HUMANS; PHENANTHRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS C VIRUS;

EID: 79954422198     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.03.002     Document Type: Article

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